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List of works by Karst Hoogsteen

1-(substituted)benzyl-5-aminoimidazole-4-carboxamides are potent orally active inhibitors of Trypanosoma cruzi in mice

scientific article published in 1991

5,6,7,8-Tetrahydrofolic acid. Conformation of the tetrahydropyrazine ring ⬇️

scientific article published on January 25, 1978

5-Methyl-5,6,7,8-tetrahydrofolic acid. Conformation of the tetrahydropyrazine ring ⬇️

scientific article published on November 10, 1979

Chemistry and Biology of Cylindrols: Novel Inhibitors of Ras Farnesyl-Protein Transferase from Cylindrocarpon lucidum

scientific article published on 01 November 1996

Circular dichroism studies of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli

scientific article published on 01 December 1972

Crystallization of human neutrophil elastase.

scientific article

Crystallographic study of a beta-lactam inhibitor complex with elastase at 1.84 A resolution

scientific article published on May 1987

Dihydrofolate Reductase: X-ray Structure of the Binary Complex with Methotrexate ⬇️

scientific article published on July 29, 1977

Dihydrofolate reductase from a methotrexate-resistant Escherichia coli: proton magnetic resonance studies of complexes with folate and methotrexate ⬇️

scientific article published on November 3, 1975

Dihydrofolate reductase from trimethoprim-resistant Escherichia coli MB 3746 and MB 3747. Purification, amino acid composition, and some kinetic properties ⬇️

scientific article published on March 25, 1979

Dihydrofolate reductase. Purification and characterization of the enzyme from an amethopterin-resistant mutant of Escherichia coli

scientific article published on 01 March 1972

Drug-induced suppression of phospholipid synthesis in HeLa cells by inhibition of choline uptake

scientific article published on May 22, 1975

Epoxyexserohilone, a Novel Metabolite fromNigrospora sphaerica

scientific article

Evidence for two reduced triphosphopyridine nucleotide binding sites on dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli.

scientific article published in September 1973

Isolation and structure determination of pycnidione, A novel bistropolone stromelysin inhibitor from a Phoma sp.

scientific article published on 25 July 2002

Metabolic studies on diphenylsulfone derivatives in chick macrophages ⬇️

scientific article published on March 15, 1975

Methotrexate binding to dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli

scientific article published on 01 September 1973

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent ⬇️

scientific article

Models for the binding of methotrexate to Escherichia coli dihydrofolate reductase: direct effect of carboxylate of aspartic acid 27 upon ultraviolet spectrum of methotrexate

scientific article published on 01 July 1981

Mouse submaxillary gland renin. Purification and properties of minor forms, which include several differently processed forms of the major gene product and a second gene product

scientific article published on 01 July 1984

Nuclear magnetic resonance spectral studies on actinomycin D. Preliminary observations on the effect of complex formation with 5'-deoxyguanylic acid ⬇️

scientific article published on September 29, 1970

Pig pancreatic anhydro-elastase. Role of the serine-195 hydroxy group in the binding of inhibitors and substrate

scientific article published on February 1987

Preliminary X-ray crystallographic data on mouse submaxillary gland renin and renin-inhibitor complexes

scientific article published on October 1984

Proton NMR studies of E. coli MB 1428 dihydrofolate reductase ⬇️

scientific article published on December 31, 1973

Proton magnetic resonance studies on Escherichia coli dihydrofolate reductase. Assignment of histidine C-2 protons in binary complexes with folates on the basis of the crystal structure with methotrexate and on chemical modifications ⬇️

scientific article published on September 10, 1979

Purification and properties of renin and gamma-renin from the mouse submaxillary gland ⬇️

scientific article published on February 25, 1983

Renin cleavage of a human kidney renin substrate analogous to human angiotensinogen, H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Ser-OH, that is human renin specific and is resistant to cathepsin D.

scientific article

Stereospecific synthesis, assignment of absolute configuration, and biological activity of the enantiomers of 3-[[[3-[2-(7-chloroquinolin-2-yl)-(E)-ethenyl]phenyl] [[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid, a potent and specifi

scientific article published in October 1990

Structure and conformation of the cis and trans isomers of 1-(p-chlorobenzylidene)-2-methyl-5-methoxyindenylacetic acid ⬇️

scientific article published on 01 February 1970

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution

scientific article

Synthesis and in vitro biological profile of all four isomers of the potent muscarinic agonist 3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-azabicyclo[2.2.1]heptane

scientific article published on March 6, 1992

Synthesis, assignment of absolute configuration, and receptor binding studies relevant to the neuroleptic activities of a series of chiral 3-substituted cyproheptadine atropisomers ⬇️

scientific article published on October 1, 1979

The crystal and molecular structure of a hydrogen-bonded complex between 1-methylthymine and 9-methyladenine

article published in 1963

Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase

scientific article published on 01 October 1995

Tryptophan-derived NK1 antagonists: conformationally constrained heterocyclic bioisosteres of the ester linkage

scientific article published on 01 March 1995

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