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List of works by Diane E Handy

A genome-wide positioning systems network algorithm for in silico drug repurposing

scientific article published on 02 August 2019

Aldosterone Inactivates the Endothelin-B Receptor via a Cysteinyl Thiol Redox Switch to Decrease Pulmonary Endothelial Nitric Oxide Levels and Modulate Pulmonary Arterial Hypertension ⬇️

scientific article published on July 11, 2012

Alpha 2 adrenergic receptor subtypes expressed in Chinese hamster ovary cells activate differentially mitogen-activated protein kinase by a p21ras independent pathway

scientific article published on 01 February 1995

Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation.

scientific article published on 14 December 2005

Autosomal dominant orthostatic hypotensive disorder maps to chromosome 18q.

scientific article published in November 1998

Bone morphogenetic protein-2 activates NADPH oxidase to increase endoplasmic reticulum stress and human coronary artery smooth muscle cell calcification.

scientific article published on 30 August 2011

Both maximal expression of selenoproteins and selenoprotein deficiency can promote development of type 2 diabetes-like phenotype in mice

scientific article

Cloning and expression of a rat brain alpha 2B-adrenergic receptor ⬇️

scientific article published on February 1, 1991

DNA sequences of the genes that encode the CTL-defined HLA-A2 variants M7 and DK1.

scientific article published in January 1987

Diverse tissue expression of rat alpha 2-adrenergic receptor genes.

scientific article published in June 1993

Epigenetic modifications: basic mechanisms and role in cardiovascular disease.

scientific article

Evidence for cell-specific regulation of transcription of the rat alpha2A-adrenergic receptor gene.

scientific article

Expression of alpha2-adrenergic receptors in normal and atherosclerotic rabbit aorta

scientific article published on 01 August 1998

Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II

scientific journal article

Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities ⬇️

scientific article published on April 10, 2011

Glutathione Peroxidase-3 Deficiency Promotes Platelet-Dependent Thrombosis In Vivo ⬇️

scientific article published on April 25, 2011

Glutathione peroxidase deficiency exacerbates ischemia-reperfusion injury in male but not female myocardium: insights into antioxidant compensatory mechanisms

scientific article published on 02 October 2009

Glutathione peroxidase-1 deficiency augments proinflammatory cytokine-induced redox signaling and human endothelial cell activation.

scientific article

High glucose-induced ubiquitination of G6PD leads to the injury of podocytes

scientific article published on 20 February 2019

Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress ⬇️

scientific article published on December 29, 2011

Hypoxia-induced suppression of c-Myc by HIF-2α in human pulmonary endothelial cells attenuates TFAM expression

scientific article published on 12 July 2017

Identification of a human salivary amylase gene. Partial sequence of genomic DNA suggests a mode of regulation different from that of mouse, Amy1

scientific article

Identification of a polymorphic glutamic acid stretch in the α2b-adrenergic receptor and lack of linkage with essential hypertension

scientific article published on 01 September 1999

Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression

scientific article

Models of experimental hypertension in mice.

scientific article

Network-based approach to prediction and population-based validation of in silico drug repurposing.

scientific article published on 12 July 2018

Pre-clinical model of severe glutathione peroxidase-3 deficiency and chronic kidney disease results in coronary artery thrombosis and depressed left ventricular function

scientific article published on 13 December 2017

Promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic stroke among young adults and children.

scientific article published on 22 November 2006

Reciprocal regulation of 11β-hydroxysteroid dehydrogenase 1 and glucocorticoid receptor expression by dexamethasone inhibits human coronary artery smooth muscle cell proliferation in vitro ⬇️

scientific article published on October 5, 2010

Regulation of alpha(2)-adrenoceptors in human vascular smooth muscle cells.

scientific article

Role of the Q10 class I regulatory element region 1 in controlling tissue-specific expression in vivo

scientific article published on 01 August 1993

Role of the postsynaptic α2-adrenergic receptor subtypes in catecholamine-induced vasoconstriction

scientific article published in February 2000

Role of the α 2B -Adrenergic Receptor in the Development of Salt-Induced Hypertension

scientific article published in January 1999

S-adenosylhomocysteine induces inflammation through NFkB: A possible role for EZH2 in endothelial cell activation

scientific article published on 23 October 2015

Selenoprotein Gene Nomenclature

scientific article published on 19 September 2016

Signals controlling alternative splicing of major histocompatibility complex H-2 class I pre-mRNA

scientific article published on 01 January 1988

Site-specific mutagenesis of the class I regulatory element the Q10 gene allows expression in non-liver tissues

scientific article published on 01 February 1989

The effect of L-arginine and creatine on vascular function and homocysteine metabolism. ⬇️

scientific article

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