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List of works by William E Hughes

A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton

scientific article (publication date: 13 June 2003)

A Critical Role for β-Catenin in Modulating Levels of Insulin Secretion from β-Cells by Regulating Actin Cytoskeleton and Insulin Vesicle Localization.

scientific article published on 24 October 2016

A Subset of Interleukin-21+ Chemokine Receptor CCR9+ T Helper Cells Target Accessory Organs of the Digestive System in Autoimmunity

scientific article published on 01 April 2011

A multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences.

scientific article

An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake

scientific article published on 01 January 2016

An actin filament population defined by the tropomyosin Tpm3.1 regulates glucose uptake

scientific article

Annexin A6 is a scaffold for PKCα to promote EGFR inactivation ⬇️

scientific article published on July 16, 2012

Application of the IMM-JPDA filter to multiple target tracking in total internal reflection fluorescence microscopy images

scientific article published on 01 January 2012

Beta 2 glycoprotein I is a substrate of thiol oxidoreductases

scientific article published on 01 September 2010

Chronic effects of fatty acids on pancreatic beta-cell function: new insights from functional genomics.

scientific article published on February 2004

Detecting protein-phospholipid interactions. Epidermal growth factor-induced activation of phospholipase D1b in situ

scientific article published on 11 April 2002

Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise.

scientific article published in January 2018

Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes

scientific article

I-motif DNA structures are formed in the nuclei of human cells.

scientific article published on 23 April 2018

IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2.

scientific article published on 17 March 2017

Identification of RhoGAP22 as an Akt-Dependent Regulator of Cell Motility in Response to Insulin ⬇️

scientific article published on October 3, 2011

Identification of a distal GLUT4 trafficking event controlled by actin polymerization

scientific article

Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis.

scientific article published on October 2005

Inhibition of H-Ras and MAPK is compensated by PKC-dependent pathways in annexin A6 expressing cells.

scientific article published on 23 September 2005

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

scientific article published on 10 November 2017

Measuring phospholipase D activity in insulin-secreting pancreatic beta-cells and insulin-responsive muscle cells and adipocytes.

scientific article

Mutations in the Saccharomyces cerevisiae gene SAC1 cause multiple drug sensitivity

scientific article published on 01 August 1999

Novel systems for dynamically assessing insulin action in live cells reveals heterogeneity in the insulin response.

scientific article published on 18 January 2013

PI4KIIα phosphorylation by GSK3 directs vesicular trafficking to lysosomes.

scientific article published in November 2014

Phospholipase D1 regulates secretagogue-stimulated insulin release in pancreatic beta-cells.

scientific article published on 14 April 2004

Phospholipid signalling through phospholipase D and phosphatidic acid.

scientific article published on August 2006

Redox control of β2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1 ⬇️

scientific article published on August 1, 2010

SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases.

scientific article

Sac phosphatase domain proteins.

scientific article

Site-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis.

scientific article

The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2.

scientific article published on 16 November 2007

The Role of Phosphoinositide 3-Kinase C2α in Insulin Signaling

scientific article published in Journal of Biological Chemistry

The Sac phosphatase domain

scientific article published on 01 April 2001

The myotubularin phosphatase MTMR4 regulates sorting from early endosomes

scientific article published on 24 August 2010

Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment.

scientific article

β-catenin is important for the development of an insulin responsive pool of GLUT4 glucose transporters in 3T3-L1 adipocytes

scientific article published on 11 March 2018

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