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List of works by Nia J Bryant

16K Fractionation of 3T3-L1 Adipocytes to Produce a Crude GLUT4-Containing Vesicle Fraction

scientific article published on March 2016

A role for the syntaxin N-terminus.

scientific article published on February 2009

Alternative routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4.

scientific article

Arabidopsis Sec1/Munc18 protein SEC11 is a competitive and dynamic modulator of SNARE binding and SYP121-dependent vesicle traffic.

scientific article published on 9 April 2013

Autoinhibition of SNARE complex assembly by a conformational switch represents a conserved feature of syntaxins.

scientific article

BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation.

scientific article published on March 2011

Building GLUT4 Vesicles: CHC22 Clathrin's Human Touch

scientific article published on 30 June 2020

CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis

scientific article published on 01 January 2020

Cellular levels of the syntaxin Tlg2p are regulated by a single mode of binding to Vps45p.

scientific article published on 25 September 2007

Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes

scientific article published on 05 March 2020

Characterization of VAMP isoforms in 3T3-L1 adipocytes: implications for GLUT4 trafficking.

scientific article

Characterization of two distinct binding modes between syntaxin 4 and Munc18c

scientific article published on 01 May 2009

Complete Membrane Fractionation of 3T3-L1 Adipocytes

scientific article published on February 2016

EFR3 and phosphatidylinositol 4-kinase IIIα regulate insulin-stimulated glucose transport and GLUT4 dispersal in 3T3-L1 adipocytes

scientific article published in 2022

Endosomal sorting of GLUT4 and Gap1 is conserved between yeast and insulin-sensitive cells.

scientific article

Functional homology of mammalian syntaxin 16 and yeast Tlg2p reveals a conserved regulatory mechanism

scientific article published on 9 June 2009

GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in Syntaxins 6 and 16 but not TGN38: involvement of an acidic targeting motif

scientific article

Homotypic vacuole fusion in yeast requires organelle acidification and not the V-ATPase membrane domain.

scientific article published in November 2013

Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13.

scientific article

Insulin stimulated GLUT4 translocation - Size is not everything!

scientific article published on 14 March 2020

Insulin stimulates syntaxin4 SNARE complex assembly via a novel regulatory mechanism

scientific journal article

Insulin-regulated trafficking of GLUT4 requires ubiquitination

scientific article

Iodixanol Gradient Centrifugation to Separate Components of the Low-Density Membrane Fraction from 3T3-L1 Adipocytes

scientific article published on February 2016

Large scale, single-cell FRET-based glucose uptake measurements within heterogeneous populations

scientific article published on 03 March 2022

Localization of a protein A-tagged Kex2 protein to the vacuole of Saccharomyces cerevisiae allows rapid purification of vacuolar membranes

scientific article published on 01 March 1995

Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking.

scientific article published on 10 August 2006

Negative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c in vitro

scientific article

Posttranslational modifications of GLUT4 affect its subcellular localization and translocation

scientific article published on 10 May 2013

Preparation of a Total Membrane Fraction from 3T3-L1 Adipocytes

scientific article published on March 2016

Proximity Ligation Assay to Study the GLUT4 Membrane Trafficking Machinery

scientific article published in January 2018

Recombinant expression of Munc18c in a baculovirus system and interaction with syntaxin4.

scientific article published on October 2003

Regulated transport of the glucose transporter GLUT4

scientific article (publication date: April 2002)

SNARE phosphorylation: a control mechanism for insulin-stimulated glucose transport and other regulated exocytic events.

scientific article published on 3 November 2017

SNARE proteins underpin insulin-regulated GLUT4 traffic.

scientific article published on 08 February 2011

Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45

scientific article published on 05 June 2013

Studies of the regulated assembly of SNARE complexes in adipocytes.

scientific article

Syntaxin 16 controls the intracellular sequestration of GLUT4 in 3T3-L1 adipocytes

scientific article published on 30 June 2006

Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells

scientific article (publication date: 8 June 2001)

The N-terminal peptide of the syntaxin Tlg2p modulates binding of its closed conformation to Vps45p.

scholarly article

The Sec1/Munc18 protein Vps45 regulates cellular levels of its SNARE binding partners Tlg2 and Snc2 in Saccharomyces cerevisiae

scientific article

The Sec1p/Munc18 (SM) protein, Vps45p, cycles on and off membranes during vesicle transport

scientific article

The Sec1p/Munc18 (SM) protein, Vps45p, cycles on and off membranes during vesicle transport.

scientific article published in November 2012

The Sec1p/Munc18 protein Vps45p binds its cognate SNARE proteins via two distinct modes.

scientific article

The Thr224Asn mutation in the VPS45 gene is associated with the congenital neutropenia and primary myelofibrosis of infancy

scientific article

The deubiquitinating enzyme USP25 binds tankyrase and regulates trafficking of the facilitative glucose transporter GLUT4 in adipocytes

scientific article published on 18 March 2019

The membrane protein alkaline phosphatase is delivered to the vacuole by a route that is distinct from the VPS-dependent pathway.

scientific article

The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins.

scientific article

The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion.

scientific article published on January 2003

Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation

scientific article (publication date: 12 September 2003)

Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4

scientific article

VPS21 controls entry of endocytosed and biosynthetic proteins into the yeast prevacuolar compartment.

scientific article

Vacuole biogenesis in Saccharomyces cerevisiae: protein transport pathways to the yeast vacuole

scientific article

mVps45 knockdown selectively modulates VAMP expression in 3T3-L1 adipocytes.

scientific article

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