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Authors whose works are in public domain in at least one jurisdiction

List of works by Joaquin Martinez-Lopez

A Next-Generation Sequencing Strategy for Evaluating the Most Common Genetic Abnormalities in Multiple Myeloma.

scientific article published on 15 November 2016

A Novel Evolutionary Pattern Revealed Using Deep Sequencing of Immunoglobulin Loci at Diagnosis and over the Course of Treatment in Multiple Myeloma Patients

scientific article published in 2016

A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis.

scientific article published on 18 July 2016

A novel deep targeted sequencing method for minimal residual disease monitoring in acute myeloid leukemia

scientific article published on 09 August 2018

A novel ex vivo high-throughput assay reveals antiproliferative effects of idelalisib and ibrutinib in chronic lymphocytic leukemia.

scientific article

A novel nano-immunoassay method for quantification of proteins from CD138-purified myeloma cells: biological and clinical utility

scientific article published on 15 March 2018

A novel targeted RNA-Seq panel identifies a subset of adult patients with acute lymphoblastic leukemia with BCR-ABL1-like characteristics

scientific article published on 24 April 2020

Absence of Contribution to a Differential Outcome of the Stringent Complete Response IMWG Category Respect to the Conventional CR in Multiple Myeloma. a Validation Analysis Based on the Pethema/GEM2012MENOS65 Phase III Clinical Trial ⬇️

scholarly article

Abstract CT080: Melflufen and dexamethasone (dex) plus bortezomib (BTZ) or daratumumab (dara) in patients (pts) with relapsed/refractory multiple myeloma (RRMM) (OP-104)

scholarly article

Acute myeloid leukemia and transcription factors: role of erythroid Krüppel-like factor (EKLF).

scientific article

Age at onset should be a major criterion for subclassification of colorectal cancer.

scientific article

Analysis of SNP Array Abnormalities in Patients with DE NOVO Acute Myeloid Leukemia with Normal Karyotype

scientific article published on 03 April 2020

Analysis of renal impairment in MM-003, a phase III study of pomalidomide + low - dose dexamethasone versus high - dose dexamethasone in refractory or relapsed and refractory multiple myeloma

scientific article published on 14 April 2016

Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry.

scientific article

Analytical and clinical validation of a novel in-house deep-sequencing method for minimal residual disease monitoring in a phase II trial for multiple myeloma

scientific article published on 17 February 2017

Antiphospholipid syndrome in a patient suffering from congenital dyserythropoietic anemia type III

scientific article published on 22 April 2015

Application of self-quenched JH consensus primers for real-time quantitative PCR of IGH gene to minimal residual disease evaluation in multiple myeloma.

scientific article

Bendamustine, bortezomib and prednisone for the treatment of patients with newly diagnosed multiple myeloma: results of a prospective phase 2 Spanish/PETHEMA trial.

scientific article published on 24 April 2015

Biological and clinical significance of dysplastic hematopoiesis in patients with newly-diagnosed multiple myeloma

scientific article published on 16 April 2020

Biomarkers for Predicting Long-Term Disease Control in Transplant-Ineligible Multiple Myeloma Patients: The Presence of an MGUS- like Signature Is the Most Relevant Predictor ⬇️

scholarly article

Bortezomib and thalidomide maintenance after stem cell transplantation for multiple myeloma: a PETHEMA/GEM trial

scientific article published on 23 January 2017

Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple m

scientific article published on 23 August 2010

Busulfan 12 mg/kg plus melphalan 140 mg/m2 versus melphalan 200 mg/m2 as conditioning regimens for autologous transplantation in newly diagnosed multiple myeloma patients included in the PETHEMA/GEM2000 study.

scientific article

CALR mutations screening should not be studied in splanchnic vein thrombosis

scientific article published on 02 February 2015

CD20-Tcb (RG6026), a Novel "2:1" Format T-Cell-Engaging Bispecific Antibody, Induces Complete Remissions in Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma: Preliminary Results from a Phase I First in Human Trial ⬇️

scholarly article

Characterization of Subclonal Changes Along Progression in Multiple Myeloma. ⬇️

scholarly article

Circulating tumor cells for comprehensive and multiregional non-invasive genetic characterization of multiple myeloma

scientific article published on 01 June 2020

Clinical Features Associated with COVID-19 Outcome in MM: First Results from International Myeloma Society Dataset

scientific article published on 06 November 2020

Clinical Outcomes of Patients with Relapsed/Refractory Follicular Lymphoma Treated with Tisagenlecleucel: Phase 2 Elara 3-Year Follow-up

scholarly article

Clinical Significance of Sensitive Flow-MRD Monitoring in Elderly Multiple Myeloma Patients on the Pethema/GEM2010MAS65 Trial ⬇️

scholarly article

Clinical and biological characterization of patients with low (0.1-2%) JAK2V617F allele burden at diagnosis

scientific article

Clinical applicability and prognostic significance of molecular response assessed by fluorescent-PCR of immunoglobulin genes in multiple myeloma. Results from a GEM/PETHEMA study.

scientific article

Clinical characteristics of patients with central nervous system relapse in BCR-ABL1-positive acute lymphoblastic leukemia: the importance of characterizing ABL1 mutations in cerebrospinal fluid

scientific article

Clinical relevance of Minimal residual Disease assessment by NGS in Multiple Myeloma ⬇️

scholarly article

Clinical significance of CD81 expression by clonal plasma cells in high-risk smoldering and symptomatic multiple myeloma patients

scientific article published on 15 February 2012

Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia

scientific article published on 01 February 2009

Clinical value of measurable residual disease testing for assessing depth, duration, and direction of response in multiple myeloma

scientific article published on 01 July 2020

Collaborative intelligence and gamification for on-line malaria species differentiation

scientific article published on 24 January 2019

Comparison of Sequential Vs Alternating Administration of Bortezomib, Melphalan, Prednisone (VMP) and Lenalidomide Plus Dexamethasone (Rd) in Elderly Pts with Newly Diagnosed Multiple Myeloma (MM) Patients: GEM2010MAS65 Trial ⬇️

scholarly article

Comparison of immunofixation, serum free light chain, and immunophenotyping for response evaluation and prognostication in multiple myeloma

scientific article published on 14 March 2011

Comparison of next-generation sequencing (NGS) and next-generation flow (NGF) for minimal residual disease (MRD) assessment in multiple myeloma

scientific article published on 30 October 2020

Comparison of the MagNA pure LC automated system and the RiboPure-Blood RNA manual method for RNA extraction from multiple myeloma bone marrow samples conserved in an RNA stabilizer.

scientific article published in April 2007

Concurrent progressive multifocal leukoencephalopathy and central nervous system infiltration by multiple myeloma: A case report.

scientific article

Conditioning regimens in autologous stem cell transplantation for multiple myeloma: a comparative study of efficacy and toxicity from the Spanish Registry for Transplantation in Multiple Myeloma

scientific article published on 01 April 2000

Copy number profiling of adult relapsed B-cell precursor acute lymphoblastic leukemia reveals potential leukemia progression mechanisms

scientific article published on 30 July 2017

Correction: Mutations in the DNA methylation pathway and number of driver mutations predict response to azacitidine in myelodysplastic syndromes

scientific article published on 20 July 2018

Corrigendum: Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients

scientific article published on 9 December 2015

Cost-Effectiveness Of Midostaurin In The Treatment Of Acute Myeloid Leukemia With The FLT3 Mutation In Spain

scientific article published on 13 November 2019

Critical analysis of the stringent complete response in multiple myeloma: contribution of sFLC and bone marrow clonality.

scientific article

Critical evaluation of ASO RQ-PCR for minimal residual disease evaluation in multiple myeloma. A comparative analysis with flow cytometry.

scientific article published on 17 July 2013

Current opinion and consensus statement regarding the diagnosis, prognosis, and treatment of patients with essential thrombocythemia: a survey of the Spanish Group of Ph-negative Myeloproliferative Neoplasms (GEMFIN) using the Delphi method.

scientific article published on 22 February 2016

Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to Bortezomib, Thalidomide and Dexamethasone (VTD) As Induction Therapy for the Treatment of Transplant Eligible Multiple Myeloma ⬇️

scholarly article

Cytogenetics and long-term survival of patients with refractory or relapsed and refractory multiple myeloma treated with pomalidomide and low-dose dexamethasone.

scientific article

Daratumumab plus carfilzomib and dexamethasone in patients with relapsed or refractory multiple myeloma

scientific article published on 21 May 2019

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard and high risk myeloma

scientific article published on 21 July 2020

Deep Response in Multiple Myeloma: A Critical Review

scientific article

Depth of Response in Multiple Myeloma: A Pooled Analysis of Three PETHEMA/GEM Clinical Trials

scientific article published on 12 May 2017

Detailed Phenotypic, Molecular and Functional Profiling of Myeloid Derived Suppressor Cells (MDSCs) in the Tumor Immune Microenvironment (TIME) of Multiple Myeloma (MM) ⬇️

scholarly article

Detailed characterization of MLH1 p.D41H and p.N710D variants coexisting in a Lynch syndrome family with conserved MLH1 expression tumors.

scientific article published on 16 September 2014

Development and evaluation of a secondary reference panel for BCR-ABL1 quantification on the International Scale

scientific article published on 25 April 2016

Differential expression of JAK2 and Src kinase genes in response to hydroxyurea treatment in polycythemia vera and essential thrombocythemia.

scientific article

Differentiation stage of myeloma plasma cells: biological and clinical significance.

scientific article

Discontinuation of tyrosine kinase inhibitor therapy in chronic myeloid leukaemia (EURO-SKI): a prespecified interim analysis of a prospective, multicentre, non-randomised, trial

scientific article

Do chronic myeloid leukemia patients with late "warning" responses benefit from "watch and wait" or switching therapy to a second generation tyrosine kinase inhibitor?

scientific article published on 27 August 2014

Do myeloproliferative neoplasms and multiple myeloma share the same genetic susceptibility loci?

scientific article published on 10 October 2020

Downregulation of specific miRNAs in hyperdiploid multiple myeloma mimics the oncogenic effect of IgH translocations occurring in the non-hyperdiploid subtype.

scientific article published on 22 October 2012

Droplet Microfluidics for the ex Vivo Expansion of Human Primary Multiple Myeloma Cells

scientific article published on 29 February 2020

Drug Discovery Testing Compounds in Patient Samples by Automated Flow Cytometry

scientific article published on 24 March 2017

Dual CD20-Targeted Therapy With Concurrent CD20-TCB and Obinutuzumab Shows Highly Promising Clinical Activity and Manageable Safety in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma: Preliminary Results From a Phase Ib Trial ⬇️

scholarly article

Dual PAK4-NAMPT Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldenström Macroglobulinemia

scientific article published on 11 September 2018

Early mortality in multiple myeloma: the time-dependent impact of comorbidity: A population-based study in 621 real-life patients

scientific article published on 28 April 2016

Early myeloma-related death in elderly patients: development of a clinical prognostic score and evaluation of response sustainability role

scientific article published on 23 February 2018

Effect of folic acid treatment on carotid intima-media thickness of patients with coronary disease

scientific article published on 17 October 2006

Efficacy and Safety Of Pomalidomide Plus Low-Dose Dexamethasone In Advanced Multiple Myeloma: Results Of Randomized Phase 2 and 3 Trials (MM-002/MM-003) ⬇️

scholarly article

Efficacy and Safety of Dasatinib in Late Suboptimal Response CML Patients a Its Relation with Lymphocytosis, Lymphocyte Migration and Chemokine Receptor Expression ⬇️

scholarly article

Elotuzumab in combination with thalidomide and low-dose dexamethasone: a phase 2 single-arm safety study in patients with relapsed/refractory multiple myeloma

scientific article published on 19 July 2016

Epigenomic profiling in polycythaemia vera and essential thrombocythaemia shows low levels of aberrant DNA methylation

scientific article published on 06 August 2011

Evaluating gene expression profiling by quantitative polymerase chain reaction to develop a clinically feasible test for outcome prediction in multiple myeloma

scientific article

Evaluation of minimal residual disease in multiple myeloma patients by fluorescent-polymerase chain reaction: the prognostic impact of achieving molecular response.

scientific article

Evaluation of the potential therapeutic benefits of macrophage reprogramming in multiple myeloma.

scientific article published on 13 September 2016

Evolving treatment patterns and outcomes in older patients (≥60 years) with AML: changing everything to change nothing?

scientific article published on 19 October 2020

Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma.

scientific article

Expression quantitative trait loci of genes predicting outcome are associated with survival of multiple myeloma patients

scientific article published on 15 July 2021

Fatal graft-versus-host disease after allogeneic stem cell transplantation in a patient recently exposed to nivolumab.

scientific article published in January 2017

Filanesib in combination with pomalidomide and dexamethasone in refractory MM patients: safety and efficacy, and association with alpha 1-acid glycoprotein (AAG) levels. Phase Ib/II Pomdefil clinical trial conducted by the Spanish MM group

scientific article published on 05 June 2020

Final Analysis, Cytogenetics, Long-Term Treatment, and Long-Term Survival In MM-003, A Phase 3 Study Comparing Pomalidomide + Low-Dose Dexamethasone (POM + LoDEX) Vs High-Dose Dexamethasone (HiDEX) In Relapsed/Refractory Multiple Myeloma (RRMM) ⬇️

scholarly article

First-in-Human Phase I Study of ABBV-838, an Antibody-Drug Conjugate Targeting SLAMF7/CS1 in Patients with Relapsed and Refractory Multiple Myeloma

scientific article published on 22 January 2020

Flow cytometry for fast screening and automated risk assessment in systemic light-chain amyloidosis

scientific article published on 12 December 2018

Fragment length analysis screening for detection of CEBPA mutations in intermediate-risk karyotype acute myeloid leukemia ⬇️

scientific article published on May 3, 2011

Frequency and clinical impact of CDKN2A/ARF/CDKN2B gene deletions as assessed by in-depth genetic analyses in adult T cell acute lymphoblastic leukemia

scientific article published on 24 July 2018

Frequency and prognostic value of resistance/intolerance to hydroxycarbamide in 890 patients with polycythaemia vera.

scientific article published on 21 December 2015

Frontline treatment of follicular lymphoma with fludarabine, cyclophosphamide, and rituximab followed by rituximab maintenance: toxicities overcome its high antilymphoma effect. Results from a Spanish Cooperative Trial (LNHF-03).

scientific article published on 28 January 2011

Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.

scientific article published on 17 January 2017

GEM2005 trial update comparing VMP/VTP as induction in elderly multiple myeloma patients: do we still need alkylators?

scientific article published on 01 September 2014

Genetic Profiling and Novel Recurrent Chromosomal Alterations in Patients with Light Chain Amyloidosis ⬇️

scholarly article

Genetic Variants and Multiple Myeloma Risk: IMMEnSE Validation of the Best Reported Associations--An Extensive Replication of the Associations from the Candidate Gene Era

article

Genetic polymorphisms associated with telomere length and risk of developing myeloproliferative neoplasms

scientific article published on 01 September 2020

Genetic polymorphisms in genes of class switch recombination and multiple myeloma risk and survival: an IMMEnSE study

article

Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients.

scientific article

Haploidentical IL-15/41BBL activated and expanded natural killer cell infusion therapy after salvage chemotherapy in children with relapsed and refractory leukemia

scientific article published on 23 February 2018

Hierarchy of mono- and biallelic TP53 alterations in multiple myeloma cell fitness

scientific article published on 24 July 2019

High-risk cytogenetics and persistent minimal residual disease by multiparameter flow cytometry predict unsustained complete response after autologous stem cell transplantation in multiple myeloma

scientific article published on 29 November 2011

How do we manufacture clinical-grade interleukin-15-stimulated natural killer cell products for cancer treatment?

scientific article published on 14 March 2018

Hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C-->T and 1298A-->C mutations in patients with inflammatory bowel disease.

scientific article published in July 2005

IKZF1/3 and CRL4-CRBN E3 ubiquitin ligase mutations and IMiD resistance in multiple myeloma

scientific article published on 26 September 2019

Identification of miRSNPs associated with the risk of multiple myeloma.

scientific article

Imaging and bone marrow assessments improve minimal residual disease prediction in multiple myeloma

scientific article published on 09 June 2019

Immunogenetic characterization of clonal plasma cells in systemic light-chain amyloidosis

scientific article published on 19 March 2020

Immunogenomic identification and characterization of granulocytic myeloid derived suppressor cells in multiple myeloma

scientific article published on 23 April 2020

Impact of genotype on leukaemic transformation in polycythaemia vera and essential thrombocythaemia

scientific article

Impact of hematologic malignancy and type of cancer therapy on COVID-19 severity and mortality: lessons from a large population-based registry study

scientific article published on 08 October 2020

Impact of prior treatment and depth of response on survival in MM-003, a randomized phase 3 study comparing pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone in relapsed/refractory multiple myeloma.

scientific article

Improving the prediction of acute myeloid leukaemia outcomes by complementing mutational profiling with ex vivo chemosensitivity

scientific article published on 18 February 2020

In vivo adhesion of malignant B cells to bone marrow microvasculature is regulated by α4β1 cytoplasmic-binding proteins.

scientific article published on 10 December 2015

Influence of GST Gene Polimorphisms in the Develovement of Liver Sinusoidal Obstructive Syndrome in Patients with Multiple Myeloma Undergoing Hematopoietic Stem Cell Transplantation. ⬇️

scholarly article

Inherited variation in the xenobiotic transporter pathway and survival of multiple myeloma patients

scientific article published on 06 August 2018

Inhibition of related JAK/STAT pathways with molecular targeted drugs shows strong synergy with ruxolitinib in chronic myeloproliferative neoplasm ⬇️

scientific article published on April 5, 2013

JAK2 exon 12 mutations were not found in liver transplant recipients with or without pretransplant portal vein thrombosis

scientific article published on 01 March 2014

Karyotype and prognosis in adult Spanish acute lymphoblastic leukemia.

scientific article published in April 2001

Kinetics of Response to Bortezomib/Thalidomide/Dexamethasone (VTD) in Multiple Myeloma: Implications for the Choice and Design of Pretransplantation Induction Regimens ⬇️

scholarly article

Living donor liver transplantation: usefulness of hemostatic and prothrombotic screening in potential donors.

scientific article published in November 2009

Long-term follow-up of donor chimerism and tolerance after human liver transplantation

scientific article published on 01 June 2009

Long-term prognostic significance of response in multiple myeloma after stem cell transplantation.

scientific article published on 11 April 2011

Longitudinal Immunogenomic Profiling of Tumor and Immune Cells for Minimally-Invasive Monitoring of Smoldering Multiple Myeloma (SMM): The Immunocell Study

scientific article published on 06 February 2021

Low expression of CD39 and CD73 genes in centenarians compared with octogenarians.

scientific article

MEK inhibition enhances the response to tyrosine kinase inhibitors in acute myeloid leukemia

scientific article published on 09 December 2019

Maintenance therapy with bortezomib plus thalidomide or bortezomib plus prednisone in elderly multiple myeloma patients included in the GEM2005MAS65 trial

scientific article published on 13 August 2012

Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma

scientific article published on 26 November 2019

Measurement of PTCH1 Expression at Diagnosis Is an Appropriate Tool for Tyrosine Kinase Inhibitors Selection in Chronic Myeloid Leukemia Patients in Chronic Phase ⬇️

scholarly article

Memory T Cells Expressing an NKG2D-CAR Efficiently Target Osteosarcoma Cells.

scientific article

Minimal Residual Disease Monitoring with Next-Generation Sequencing Methodologies in Hematological Malignancies

scientific article published on 10 June 2019

Minimal residual disease monitoring and immune profiling in multiple myeloma in elderly patients

scientific article

Molecular profiling refines minimal residual disease-based prognostic assessment in adults with Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia

scientific article published on 07 August 2019

Monitoring of clonal evolution of acute myeloid leukemia identifies the leukemia subtype, clinical outcome and potential new drug targets for post-remission strategies or relapse

scientific article published on 30 July 2020

Multidimensional Immunophenotyping Identifies Hallmarks of Systemic Light-Chain Amyloidosis (AL) and Maps the Disease in the Crossroad between MGUS and Multiple Myeloma (MM) ⬇️

scholarly article

Multiple myeloma and SARS-CoV-2 infection: clinical characteristics and prognostic factors of inpatient mortality

scientific article published on 19 October 2020

Multiple myeloma patients have a specific serum metabolomic profile that changes after achieving complete remission

scientific article published on 19 July 2013

Mutational screening of newly diagnosed multiple myeloma patients by deep targeted sequencing

scientific article published on 28 June 2018

Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia.

scientific article published on 30 May 2017

Mutations in the DNA methylation pathway and number of driver mutations predict response to azacitidine in myelodysplastic syndromes

scientific article published on 27 October 2017

Myeloablative treatments for multiple myeloma: update of a comparative study of different regimens used in patients from the Spanish registry for transplantation in multiple myeloma.

scientific article published in January 2002

Myeloproliferative neoplasm in a thalassaemic patient: response to treatment with a JAK inhibitor.

scientific article

NKG2D-CAR Transduced Primary Natural Killer Cells Efficiently Target Multiple Myeloma Cells ⬇️

scholarly article

Natural killer cell lines preferentially kill clonogenic multiple myeloma cells and decrease myeloma engraftment in a bioluminescent xenograft mouse model.

scientific article

Networking for advanced molecular diagnosis in acute myeloid leukemia patients is possible: the PETHEMA NGS-AML project

scientific article published on 12 November 2020

Next Generation Flow for highly sensitive and standardized detection of minimal residual disease in multiple myeloma.

scientific article published on 20 January 2017

No Evidence that CD33 rs12459419 Polymorphism Predicts Gemtuzumab Ozogamicin Response in Consolidation Treatment of Acute Myeloid Leukemia Patients: Experience of the PETHEMA Group

scientific article published in 2022

Non-Invasive Genetic Profiling Is Highly Applicable in Multiple Myeloma (MM) through Characterization of Circulating Tumor Cells (CTCs) ⬇️

scholarly article

Novel treatment strategy with autologous activated and expanded natural killer cells plus anti-myeloma drugs for multiple myeloma

scientific article

Obesity is an independent risk factor for pre-transplant portal vein thrombosis in liver recipients ⬇️

scientific article published on August 21, 2012

Ocena minimalnej choroby resztkowej w szpiczaku plazmocytowym

scholarly article published on 23 November 2017

Oncogenic targets, magnitude of benefit, and market pricing of antineoplastic drugs

scientific article published on 23 May 2011

Outcomes with two different schedules of bortezomib, melphalan, and prednisone (VMP) for previously untreated multiple myeloma: matched pair analysis using long-term follow-up data from the phase 3 VISTA and PETHEMA/GEM05 trials

scientific article

PTCH1 is a reliable marker for predicting imatinib response in chronic myeloid leukemia patients in chronic phase

scientific article published on 13 July 2017

Papain-treated panels are a simple method for the identification of alloantibodies in multiple myeloma patients treated with anti-CD38-based therapies

scientific article

Performance of the myelofibrosis secondary to PV and ET-prognostic model (MYSEC-PM) in a series of 262 patients from the Spanish registry of myelofibrosis.

scientific article published on 22 September 2017

Persistent Benefit of VTD (Bortezomib/Thalidomide/Dexamethasone) As Pretransplant Induction Therapy for Multiple Myeloma: Long-Term Follow-up of a Randomized Phase 3 Pethema/GEM Study ⬇️

scholarly article

Phenotypic, transcriptomic, and genomic features of clonal plasma cells in light-chain amyloidosis

scientific article published on 11 April 2016

Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, open-label, phase 3 trial

scientific article

Population Pharmacological Profiles Of AML Treatments In Patient Samples By Automated Flow Cytometry; A Bridge To Individualized Medicine ⬇️

scholarly article

Predicting long-term disease control in transplant-ineligible patients with multiple myeloma: impact of an MGUS-like signature

scientific article published on 18 March 2019

Prediction of peripheral neuropathy in multiple myeloma patients receiving bortezomib and thalidomide: a genetic study based on a single nucleotide polymorphism array.

scientific article published on 8 September 2016

Predictive factors for anemia response to erythropoiesis-stimulating agents in myelofibrosis

scientific article published on 23 December 2016

Preliminary Results from a Phase I Study of Isatuximab (ISA) in Combination with Bortezomib, Lenalidomide, Dexamethasone (VRd), and in Patients with Newly Diagnosed Multiple Myeloma (NDMM) Non-Eligible for Transplant ⬇️

scholarly article

Prognostic Value Of Deep Sequencing Approach For Minimal Residual Disease (MRD) Detection In Multiple Myeloma Patients ⬇️

scholarly article

Prognostic risk models for transplant decision-making in myelofibrosis.

scientific article

Prognostic significance of copy number alterations in adolescent and adult patients with precursor B acute lymphoblastic leukemia enrolled in PETHEMA protocols.

scientific article

Prognostic utility of serum free light chain ratios and heavy-light chain ratios in multiple myeloma in three PETHEMA/GEM phase III clinical trials

scientific article published in PLoS ONE

Prognostic value of antigen expression in multiple myeloma: a PETHEMA/GEM study on 1265 patients enrolled in four consecutive clinical trials.

scientific article

Prognostic value of deep sequencing method for minimal residual disease detection in multiple myeloma

scientific article

Prognostic value of tumoral ploidy in a series of spanish patients with acute lymphoblastic leukemia

scientific article published on 01 October 2000

Protein Carbonylation and Lipid Peroxidation in Hematological Malignancies

scientific article published on 01 December 2020

Protein Carbonylation in Patients with Myelodysplastic Syndrome: An Opportunity for Deferasirox Therapy

scientific article published on 24 October 2019

Proteomic analysis reveals heat shock protein 70 has a key role in polycythemia Vera.

scientific article

Quantitative assessment of PML-RARa and BCR-ABL by two real-time PCR instruments: multiinstitutional laboratory trial.

scientific article published in June 2004

Quantitative expression of Ikaros, IRF4, and PSMD10 proteins predicts survival in VRD-treated patients with multiple myeloma

scientific article published on 01 December 2020

Rapid detection of KIT mutations in core-binding factor acute myeloid leukemia using high-resolution melting analysis

scientific article published on 30 July 2009

Real Life Long-Term Survival Analysis in Patients with Chronic Myeloid Leukemia Treated with Tkis in Spain ⬇️

scholarly article

Real-time PCR quantification of haematopoietic chimerism after transplantation: a comparison between TaqMan and hybridization probes technologies

scientific article published on 12 May 2009

Recipient and donor thrombophilia and the risk of portal venous thrombosis and hepatic artery thrombosis in liver recipients.

scientific article

Recommendations for the evaluation and management of patients with rheumatic autoimmune and inflammatory diseases during the reproductive age, pregnancy, postpartum and breastfeeding.

scientific article published on 16 June 2016

Relationship between deoxycytidine kinase (DCK) genotypic variants and fludarabine toxicity in patients with follicular lymphoma ⬇️

scientific article published on October 27, 2010

Remission status defined by immunofixation vs. electrophoresis after autologous transplantation has a major impact on the outcome of multiple myeloma patients

scientific article published on 01 May 2000

Response rate to the treatment of Waldenström macroglobulinemia: A meta-analysis of the results of clinical trials.

scientific article

Response to imatinib mesylate in patients with hypereosinophilic syndrome.

scientific article

Restoring Innate and Adaptive Immune Repertoire in Multiple Myeloma for Therapeutic Application ⬇️

scholarly article

Results from HARMONY: an open-label, multicenter, 2-arm, phase 1b, dose-finding study assessing the safety and efficacy of the oral combination of ruxolitinib and buparlisib in patients with myelofibrosis

scientific article published on 09 May 2019

Risk of thrombosis according to need of phlebotomies in patients with polycythemia vera treated with hydroxyurea

scientific article published on 29 September 2016

Role of urine immunofixation in the complete response assessment of MM patients other than light-chain-only disease

scientific article published on 22 April 2019

Ruxolitinib in Combination with Nilotinib and Prednisolone, a New Synergistic Approach to Treat Myelofibrosis ⬇️

scholarly article

Ruxolitinib in combination with prednisone and nilotinib exhibit synergistic effects in human cells lines and primary cells from myeloproliferative neoplasms

scientific article published on 13 December 2018

Simplified in-House Deep Sequencing Method of Inmunoglobulin Genes for Minimal Residual Dissease Quantification and Risk Stratification in Multiple Myeloma ⬇️

scholarly article

Spectrum and functional validation of PSMB5 mutations in multiple myeloma

scientific article published on 19 July 2018

Surgical management of hereditary colorectal cancer: surgery based on molecular analysis and family history

scientific article published on 01 August 2009

Surgical resection of a solitary pancreatic metastasis from colorectal cancer: a new step to a cure?

scientific article published on 01 November 2008

Switching to second-generation tyrosine kinase inhibitor improves the response and outcome of frontline imatinib-treated patients with chronic myeloid leukemia with more than 10% of BCR-ABL/ABL ratio at 3 months.

scientific article published on 10 March 2015

TYK2 Variants in B-Acute Lymphoblastic Leukaemia

scientific article published on 28 November 2020

Tandem transplants with different high-dose regimens improve the complete remission rates in multiple myeloma. Results of a Grupo Español de Síndromes Linfoproliferativos/Trasplante Autólogo de Médula Osea phase II trial.

scientific article published in January 2003

Targeted Genomic Mutation Panel (M3 P) Results from 504 Multiple Myeloma (MM) Patients ⬇️

scholarly article

The International Prognostic Scoring System does not accurately discriminate different risk categories in patients with post-essential thrombocythemia and post-polycythemia vera myelofibrosis

scientific article published on 31 January 2014

The OP-104 Anchor Study: A Phase 1/2 Study of Safety and Efficacy of Melflufen and Dexamethasone in Combination with Either Bortezomib or Daratumumab in Patients with Rrmm; First Report on Phase 1 Data ⬇️

scholarly article

The Presence of MDS-like Phenotypic Abnormalities (MDS-PA) Identifies Newly Diagnosed Multiple Myeloma (MM) Patients with MDS/AML-Related Somatic Mutations and Inferior Survival ⬇️

scholarly article

The clinical significance of stringent complete response in multiple myeloma is surpassed by minimal residual disease measurements

scientific article published on 31 August 2020

The poor prognosis of low hypodiploidy in adults with B-cell precursor acute lymphoblastic leukaemia is restricted to older adults and elderly patients

scientific article published on 27 March 2019

The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data

scientific article published on 26 October 2019

The use of fluorescent molecular beacons in real time PCR of IgH gene rearrangements for quantitative evaluation of multiple myeloma

article

Timing treatment for smoldering myeloma: is earlier better?

scientific article published on 04 April 2019

Tocilizumab for the treatment of adult patients with severe COVID-19 pneumonia: a single-center cohort study

scientific article published on 16 July 2020

Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination

scientific article published on 08 October 2019

Transcriptomic Profiling of Circulating Tumor Cells (CTCs) in Multiple Myeloma (MM): A New Model to Understand Disease Dissemination ⬇️

scholarly article

Treatment for patients with newly diagnosed multiple myeloma in 2015.

scientific article published on 12 June 2015

Two distinct molecular subtypes of chronic lymphocytic leukemia give new insights on the pathogenesis of the disease and identify novel therapeutic targets

scientific article published on 12 May 2015

Type 2 diabetes-related variants influence the risk of developing multiple myeloma: results from the IMMEnSE consortium

scientific article published on 22 June 2015

Typical chronic myelogenous leukemia with e19a2 BCR/ABL transcript. Report of two cases

scientific article published on 01 August 2002

Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas

scientific article published on 01 January 2020

Understanding the Cellular Origin and Pathogenic Transcriptional Programs in Multiple Myeloma (MM) and Light-Chain Amyloidosis (AL) through the Dissection of the Normal Plasma Cell (PC) Development ⬇️

scholarly article

Use of Sorafenib as an effective treatment in an AML patient carrying a new point mutation affecting the Juxtamembrane domain of FLT3.

scientific article published on 12 June 2012

Usefulness of Serum-Free-Light-Chains-Ratio (SFLCR) and Serum Heavy-Light-Chains-Ratio (SHLCR) in Multiple Myeloma in the Context of Three GEM/Pethema Clinical Trials ⬇️

scholarly article

VTD (Bortezomib/Thalidomide/Dexamethasone) As Pretransplant Induction Therapy for Multiple Myeloma: Definitive Results of a Randomized Phase 3 Pethema/GEM Study ⬇️

scholarly article

Validity test study of JAK2 V617F and allele burden quantification in the diagnosis of myeloproliferative diseases.

scientific article published on 25 June 2008

Whole-exome sequencing in splenic marginal zone lymphoma reveals mutations in genes involved in marginal zone differentiation.

scientific article

Wilms Tumor 1 gene expression levels improve risk stratification in AML patients. Results of a multicentre study within the Spanish Group for Molecular Biology in Haematology

scientific article published on 3 April 2017

hnRNP K Is a Haploinsufficient Tumor Suppressor that Regulates Proliferation and Differentiation Programs in Hematologic Malignancies.

scientific article

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