List of works by Ann Richmond

A Requirement for p120-catenin in the metastasis of invasive ductal breast cancer

scientific article published on 23 October 2020

A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells

scientific article published on 28 December 2001

A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets

scientific article

Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis

scientific article

Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling

scientific article

Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling

scientific article published on 16 July 2015

Adaptor protein2 (AP2) orchestrates CXCR2-mediated cell migration

scientific article published on April 2014

Altered CXCR2 signaling in beta-arrestin-2-deficient mouse models

scientific article published on October 2005

Antioxidants tiron and N-acetyl-L-cysteine differentially mediate apoptosis in melanoma cells via a reactive oxygen species-independent NF-kappaB pathway

scientific article published on 30 January 2007

Augmenting chemosensitivity of malignant melanoma tumors via proteasome inhibition: implication for bortezomib (VELCADE, PS-341) as a therapeutic agent for malignant melanoma

scientific article published on July 2004

BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways

scientific article published on February 2006

Bimodal analysis reveals a general scaling law governing nondirected and chemotactic cell motility.

scientific article

Bortezomib augments lymphocyte stimulatory cytokine signaling in the tumor microenvironment to sustain CD8+T cell antitumor function.

scientific article published on 29 December 2016

CCAAT displacement protein regulates nuclear factor-kappa beta-mediated chemokine transcription in melanoma cells

scientific article published on April 2007

CCR9 homes metastatic melanoma cells to the small bowel

scientific article published on 01 February 2008

CXC chemokines and their receptors: a case for a significant biological role in cutaneous wound healing

scientific article

CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer

scientific article

CXCR4 drives the metastatic phenotype in breast cancer through induction of CXCR2 and activation of MEK and PI3K pathways

scientific article

Cell surface heparan sulfate participates in CXCL1-induced signaling

scientific article (publication date: 4 February 2003)

Chemokine Regulation of Neutrophil Infiltration of Skin Wounds

scientific article

Chemokine modulation of the tumor microenvironment

scientific article published on 22 April 2010

Chemokine receptor internalization and intracellular trafficking

scientific article

Chemokine research moves on.

scientific article published on 15 January 2011

Chemokines Modulate Immune Surveillance in Tumorigenesis, Metastasis, and Response to Immunotherapy

Chemokines and chemokine receptors: new insights into cancer-related inflammation.

scientific article published on 15 February 2010

Chemokines in health and disease

scientific article published on 09 January 2011

Chemokines, macrophage inflammatory protein-2 and stromal cell-derived factor-1α, suppress amyloid β-induced neurotoxicity

scientific article published on 17 June 2011

Co-Clinical Imaging Resource Program (CIRP): Bridging the Translational Divide to Advance Precision Medicine

scientific article published on 01 September 2020

Combinatorial approach to cancer immunotherapy: strength in numbers

scientific article published on 2 June 2016

Combined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses

scientific article published on 19 March 2015

Combining an Aurora Kinase Inhibitor and a Death Receptor Ligand/Agonist Antibody Triggers Apoptosis in Melanoma Cells and Prevents Tumor Growth in Preclinical Mouse Models

scientific article

Conditional ablation of Ikkb inhibits melanoma tumor development in mice

scientific article

Connecting the Dots: Therapy-Induced Senescence and a Tumor-Suppressive Immune Microenvironment

scientific article published on 30 December 2015

Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-kappaB and tumor progression.

scientific article

Correlative studies investigating effects of PI3K inhibition on peripheral leukocytes in metastatic breast cancer: potential implications for immunotherapy

scientific article published on 07 August 2020

Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer

scientific article

Deletion of the COOH-terminal domain of CXC chemokine receptor 4 leads to the down-regulation of cell-to-cell contact, enhanced motility and proliferation in breast carcinoma cells

scientific article published on June 2006

Development of novel murine mammary imaging windows to examine wound healing effects on leukocyte trafficking in mammary tumors with intravital imaging

scientific article

Differential regulation of CXCR2 trafficking by Rab GTPases

scientific article published on 31 October 2002

Disparities in Uveal Melanoma: Patient Characteristics

scientific article

Effects of flow and diffusion on chemotaxis studies in a microfabricated gradient generator

scientific article

Engineered microfluidic bioreactor for examining the three-dimensional breast tumor microenvironment

scientific article published on 07 May 2018

Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment

scientific article published on 30 March 2016

Expression of activated Akt in benign nevi, Spitz nevi and melanomas

scientific article published in August 2007

Fine Tuning the Transcriptional Regulation of the CXCL1 Chemokine ⬇️

scientific article published on January 1, 2003

Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids

scientific article published on 24 July 2020

Functional characterization of chimpanzee cytomegalovirus chemokine, vCXCL-1(CCMV)

scientific article published on 11 April 2007

How do chemokine/chemokine receptor activations affect tumorigenesis?

scientific article published on January 2004

Hsc/Hsp70 interacting protein (hip) associates with CXCR2 and regulates the receptor signaling and trafficking ⬇️

scientific article

Hypoxia enhances CXCR4 expression in human microvascular endothelial cells and human melanoma cells

scientific article published on 26 June 2007

INK4a/ARF [corrected] inactivation with activation of the NF-κB/IL-6 pathway is sufficient to drive the development and growth of angiosarcoma

scientific article published on 26 July 2012

IQGAP1 is a novel CXCR2-interacting protein and essential component of the "chemosynapse".

scientific article

Impaired healing of nitrogen mustard wounds in CXCR2 null mice ⬇️

scientific article published on May 1, 2003

Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes

scientific article

LIM and SH3 protein-1 modulates CXCR2-mediated cell migration

scientific article

Loss of CXCR4 in Myeloid Cells Enhances Antitumor Immunity and Reduces Melanoma Growth through NK Cell and FASL Mechanisms

scientific article published on 14 August 2018

MDM2 Antagonists Counteract Drug-Induced DNA Damage.

scientific article

MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21

scientific article published on 01 August 2019

Mdm2 and aurora kinase a inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cells

scientific article

Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy.

scientific article

Metastatic Melanoma Patient-derived Xenografts Respond to MDM2 Inhibition as a Single Agent or in Combination with BRAF/MEK Inhibition

scientific article published on 31 March 2020

Microfluidic switching system for analyzing chemotaxis responses of wortmannin-inhibited HL-60 cells

scientific article published on August 2008

Micrometastatic Dormancy in Uveal Melanoma: A Comprehensive Review of the Evidence, Mechanisms, and Implications for Future Adjuvant Therapies

scientific article published on January 2017

Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy

scientific article

Monomeric and dimeric CXCL8 are both essential for in vivo neutrophil recruitment

scientific article (publication date: 2010)

Mouse xenograft models vs GEM models for human cancer therapeutics

scientific article

Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies

scientific article published on 02 January 2020

Myeloid IKKβ promotes antitumor immunity by modulating CCL11 and the innate immune response

scientific article published on 21 October 2014

NF-kappaB activation in melanoma

scientific article

NF-κB inducing kinase: A key regulator in the immune system and in cancer ⬇️

scientific article published on 03 August 2010

Nf-kappa B, chemokine gene transcription and tumour growth

scientific article

Opposing roles of murine duffy antigen receptor for chemokine and murine CXC chemokine receptor-2 receptors in murine melanoma tumor growth

scientific article

PAK1 kinase is required for CXCL1-induced chemotaxis.

scientific article

PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses

scientific article published on 21 December 2016

Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis

scientific article

Passage-dependent cancerous transformation of human mesenchymal stem cells under carcinogenic hypoxia

scientific article published on 08 April 2013

Pharmacokinetics, Tissue Localization, Toxicity, and Treatment Efficacy in the First Small Animal (Rabbit) Model of Intra-Arterial Chemotherapy for Retinoblastoma

scientific article published in January 2018

Phase II trial of bortezomib plus doxorubicin in hepatocellular carcinoma (E6202): a trial of the Eastern Cooperative Oncology Group

scientific article

Potential role for Duffy antigen chemokine-binding protein in angiogenesis and maintenance of homeostasis in response to stress

scientific article

Preparation of (-)-Nutlin-3 using enantioselective organocatalysis at decagram scale.

scientific article published on 15 October 2013

RAF265 inhibits the growth of advanced human melanoma tumors

scientific article published on 20 February 2012

Rab11-family interacting protein 2 and myosin Vb are required for CXCR2 recycling and receptor-mediated chemotaxis

scientific article

Rabbit Model of Intra-Arterial Chemotherapy Toxicity Demonstrates Retinopathy and Vasculopathy Related to Drug and Dose, Not Procedure or Approach

article

RhoB plays an essential role in CXCR2 sorting decisions

scientific article published on 03 April 2007

Role of CXCL1 in tumorigenesis of melanoma.

scientific article

Role of chemokines in tumor growth

scientific article

Role of nuclear factor-kappa B in melanoma

scientific article

Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials

scientific article (publication date: 2012)

Short tail with skin lesion phenotype occurs in transgenic mice with keratin-14 promoter-directed expression of mutant CXCR2.

scientific article

Study of Chemotaxis and Cell-Cell Interactions in Cancer with Microfluidic Devices

scientific article published on 24 November 2015

Systemic targeting inhibitor of kappaB kinase inhibits melanoma tumor growth

scientific article published on April 2007

Targeted Deletion of CXCR2 in Myeloid Cells Alters the Tumor Immune Environment to Improve Antitumor Immunity

scientific article published on 11 November 2020

Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence.

scientific article published on 25 November 2012

Th9 and Th17 cells: the controversial twins in cancer immunity

scientific article published on 02 June 2020

The C-terminal domain LLKIL motif of CXCR2 is required for ligand-mediated polarization of early signals during chemotaxis

scientific article

The Duffy antigen modifies systemic and local tissue chemokine responses following lipopolysaccharide stimulation

scientific article published on December 2006

The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity

scientific article

The IL sequence in the LLKIL motif in CXCR2 is required for full ligand-induced activation of Erk, Akt, and chemotaxis in HL60 cells

scientific article

The Yin/Yan of CCL2: a minor role in neutrophil anti-tumor activity in vitro but a major role on the outgrowth of metastatic breast cancer lesions in the lung in vivo

scientific article

The angiostatic activity of interferon-inducible protein-10/CXCL10 in human melanoma depends on binding to CXCR3 but not to glycosaminoglycan

scientific article published on June 2004

The carboxyl-terminal PDZ ligand motif of chemokine receptor CXCR2 modulates post-endocytic sorting and cellular chemotaxis

scientific article

The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions

scientific article

The dynamic yin-yang interaction of CXCR4 and CXCR7 in breast cancer metastasis

scientific article published on 26 January 2012

The good and the bad of chemokines/chemokine receptors in melanoma

scientific article published on 14 February 2009

The lymphotoxin-beta receptor is an upstream activator of NF-kappaB-mediated transcription in melanoma cells

scientific article published on 17 March 2008

The role of NF-kB in modulating antitumor immunity

scientific article published on 20 October 2015

The role of chemokines in intestinal inflammation and cancer

scientific article published on 04 September 2009

Tumor Characteristics, Genetics, Management, and the Risk of Metastasis in Uveal Melanoma

scientific article published on 29 April 2016

Using avatars to win the fight over BRAF inhibitor resistance.

scientific article

VASP is a CXCR2-interacting protein that regulates CXCR2-mediated polarization and chemotaxis

scientific article published on 12 May 2009

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