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List of works by Mary Roberts

A Role for Weak Electrostatic Interactions in Peripheral Membrane Protein Binding

scientific article published on March 2016

A molecular-imprint nanosensor for ultrasensitive detection of proteins

scientific article

An iron-dependent bacterial phospholipase D reminiscent of purple acid phosphatases

scientific article

Antigen receptor-mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth

scientific article published on 31 January 2006

Asymmetric Syntheses of L,L- and L,D-di-myo-inositol-1,1'-phosphate and their behavior as stabilizers of enzyme activity at extreme temperatures

scientific article

Avoidance of autophagy mediated by PlcA or ActA is required for Listeria monocytogenes growth in macrophages

scientific article

Ca2+-independent binding of anionic phospholipids by phospholipase C δ1 EF-hand domain

scientific article

Cation-π interactions as lipid-specific anchors for phosphatidylinositol-specific phospholipase C

scientific article published on 08 April 2013

Chemistry and biology of deoxy-myo-inositol phosphates: stereospecificity of substrate interactions within an archaeal and a bacterial IMPase

scientific article published in December 2004

Cloning, overexpression, and characterization of a bacterial Ca2+-dependent phospholipase D

scientific article

Compatible solute effects on thermostability of glutamine synthetase and aspartate transcarbamoylase from Methanococcus jannaschii.

scientific article published on 25 August 2005

Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity

scientific article

Correlation of vesicle binding and phospholipid dynamics with phospholipase C activity: insights into phosphatidylcholine activation and surface dilution inhibition

scientific article published on 31 March 2009

Cross-linking phosphatidylinositol-specific phospholipase C traps two activating phosphatidylcholine molecules on the enzyme

scientific article

Crystal Structure of a Trapped Catalytic Intermediate Suggests that Forced Atomic Proximity Drives the Catalysis of mIPS ⬇️

scientific article published on December 7, 2011

Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop

scientific article

Crystal structure of the tetrameric inositol 1-phosphate phosphatase (TM1415) from the hyperthermophile, Thermotoga maritima

scientific article

Cutting edge: IL-4-mediated protection of primary B lymphocytes from apoptosis via Stat6-dependent regulation of glycolytic metabolism

scientific article published in October 2007

Cytotoxic amphiphiles and phosphoinositides bind to two discrete sites on the Akt1 PH domain

scientific article published on 10 January 2014

Defining a Viral Membrane-Remodeling Complex on an Atomic Level

scientific article published on January 2017

Defining specific lipid binding sites for a peripheral membrane protein in situ using subtesla field-cycling NMR.

scientific article

Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C

scientific article

Dissection of the steps of phospholipase C beta 2 activity that are enhanced by G beta gamma subunits

scientific article published in February 2005

Does changing the predicted dynamics of a phospholipase C alter activity and membrane binding?

scientific article published on 8 January 2013

Dynamic Characteristics of Guanosine-5'-monophosphate Reductase Complexes Revealed by High-Resolution 31P Field-Cycling NMR Relaxometry.

scientific article published on 16 March 2018

Enzyme-substrate-cofactor dynamical networks revealed by high resolution field cycling relaxometry

scientific article published on 01 June 2020

Enzymology with a spin-labeled phospholipase C: soluble substrate binding by 31P NMR from 0.005 to 11.7 T

scientific article

Expression and characterization of a heterodimer of Streptomyces chromofuscus phospholipase D.

scientific article published in December 2004

Fluorescence correlation spectroscopy of phosphatidylinositol-specific phospholipase C monitors the interplay of substrate and activator lipid binding

scientific article published on July 2009

Fluorinated Aromatic Amino Acids Distinguish Cation-π Interactions from Membrane Insertion

scientific article published on 19 June 2015

Genomic identification and in vitro reconstitution of a complete biosynthetic pathway for the osmolyte di-myo-inositol-phosphate.

scholarly article

High-resolution 31p field cycling NMR as a probe of phospholipid dynamics

scientific article published in October 2004

High-resolution field-cycling NMR studies of a DNA octamer as a probe of phosphodiester dynamics and comparison with computer simulation

scientific article

Identification of hydrophobic interactions between proteins and lipids: free fatty acids activate phospholipase C delta1 via allosterism

scientific article

Inhibition of phosphatidylinositol 3-kinase-mediated glucose metabolism coincides with resveratrol-induced cell cycle arrest in human diffuse large B-cell lymphomas

scientific article published on 15 September 2006

Inositol in bacteria and archaea

scientific article published on January 2006

Insights into the structural specificity of the cytotoxicity of 3-deoxyphosphatidylinositols

scientific article

Interfacial Aromatics Mediating Cation-π Interactions with Choline-Containing Lipids Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted below the Phosphates

scientific article published on 03 July 2019

Interfacial Choline-Aromatic Cation-Pi Interactions Can Contribute as Much to Peripheral Protein Affinity for Membranes as Aromatics Inserted Below the Phosphates

scholarly article published 5 June 2019

Investigating the interfacial binding of bacterial phosphatidylinositol-specific phospholipase C.

scientific article

Itaconic acid is a mammalian metabolite induced during macrophage activation

scientific article published on 27 September 2011

Listeria monocytogenes phosphatidylinositol-specific phospholipase C: Kinetic activation and homing in on different interfaces

scientific article

Mobile loop mutations in an archaeal inositol monophosphatase: modulating three-metal ion assisted catalysis and lithium inhibition

scientific article published on February 2010

Modulation of Bacillus thuringiensis Phosphatidylinositol-specific Phospholipase C Activity by Mutations in the Putative Dimerization Interface

scientific article

Morphologic Patterns Formed by the Anomalous Fibers Occurring Along the Anterior Capsule of the Crystalline Lens in People With the Long Anterior Zonule Trait.

scientific article published on 14 February 2017

Mutagenesis of Putative Catalytic and Regulatory Residues of Streptomyces chromofuscus Phospholipase D Differentially Modifies Phosphatase and Phosphodiesterase Activities ⬇️

scientific article published on October 13, 2003

Mutation of two active-site residues converts a phosphatidylinositol-specific phospholipase C to a glucose phosphatase

scientific article published in February 2004

Non-HKD phospholipase D enzymes: new players in phosphatidic acid signaling?

scientific article

Optimizing the Interfacial Binding and Activity of a Bacterial Phosphatidylinositol-specific Phospholipase C ⬇️

scientific article published on April 24, 2003

Organic compatible solutes of halotolerant and halophilic microorganisms

scientific article

Osmoadaptation and osmoregulation in archaea: update 2004.

scientific article published in September 2004

Phosphatidylcholine "wobble" in vesicles assessed by high-resolution 13C field cycling NMR spectroscopy

scientific article published on March 2009

Phosphohydrolase and transphosphatidylation reactions of two Streptomyces phospholipase D enzymes: covalent versus noncovalent catalysis

scientific article

Phospholipid bilayer surface configuration probed quantitatively by (31)P field-cycling NMR.

scholarly article

Phospholipid reorientation at the lipid/water interface measured by high resolution 31P field cycling NMR spectroscopy

scientific article

Phospholipid-binding sites of phosphatase and tensin homolog (PTEN): exploring the mechanism of phosphatidylinositol 4,5-bisphosphate activation

scientific article

Probing the mechanism of the Archaeoglobus fulgidus inositol-1-phosphate synthase

scientific article published on 14 January 2005

Quantifying transient interactions between Bacillus phosphatidylinositol-specific phospholipase-C and phosphatidylcholine-rich vesicles.

scientific article published on 23 December 2014

Reaching for mechanistic consensus across life kingdoms: structure and insights into catalysis of the myo-inositol-1-phosphate synthase (mIPS) from Archaeoglobus fulgidus

scientific article published on 01 January 2005

Recombinant broad-range phospholipase C from Listeria monocytogenes exhibits optimal activity at acidic pH.

scientific article published on 11 March 2016

Reflections on the journey: six short stories ⬇️

scientific article published on November 7, 2011

Remnants of the anterior tunica vasculosa lentis and long anterior lens zonules

scientific article published on September 2014

Role of helix B residues in interfacial activation of a bacterial phosphatidylinositol-specific phospholipase C.

scientific article

Role of tryptophan residues in interfacial binding of phosphatidylinositol-specific phospholipase C.

scientific article published on 23 March 2002

Rotation of lipids in membranes: molecular dynamics simulation, 31P spin-lattice relaxation, and rigid-body dynamics

scientific article

Search and Subvert: Minimalist Bacterial Phosphatidylinositol-Specific Phospholipase C Enzymes

Solute accumulation in the deep-sea bacterium Photobacterium profundum

scientific article

Spectroscopic characterization of the EF-hand domain of phospholipase C delta1: identification of a lipid interacting domain.

scientific article published in August 2005

Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable π-Cation Latched Loop ⬇️

scientific article published on March 16, 2012

Structure of the inositol-1-phosphate cytidylyltransferase from Thermotoga maritima

scientific article

Substrate and Cofactor Dynamics on Guanosine Monophosphate Reductase Probed by High Resolution Field Cycling 31P NMR Relaxometry.

scientific article published on 9 September 2016

The Cation-  Box Is a Specific Phosphatidylcholine Membrane Targeting Motif

scientific article

The structure of the R184A mutant of the inositol monophosphatase encoded by suhB and implications for its functional interactions in Escherichia coli.

scientific article published on 25 July 2007

The temperature dependence of the inositol monophosphatase Km correlates with accumulation of di-myo-inositol 1,1'-phosphate in Archaeoglobus fulgidus

scientific article published in March 2006

Understanding the stereospecific interactions of 3-deoxyphosphatidylinositol derivatives with the PTEN phosphatase domain

scientific article published on 20 May 2010

Unexpected similarity in regulation between an archaeal inositol monophosphatase/fructose bisphosphatase and chloroplast fructose bisphosphatase

scientific article published on April 2003

Using O-(n-alkyl)-N-(N,N'-dimethylethyl)phosphoramidates to investigate the role of Ca2+ and interfacial binding in a bacterial phospholipase D

scientific article published on 01 July 2003

Water-miscible organic cosolvents enhance phosphatidylinositol-specific phospholipase C phosphotransferase as well as phosphodiesterase activity

scientific article

d-3-Deoxy-dioctanoylphosphatidylinositol induces cytotoxicity in human MCF-7 breast cancer cells via a mechanism that involves downregulation of the D-type cyclin-retinoblastoma pathway

scientific article published on 3 September 2016

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