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List of works by Alan F List

A Multi-Institution Phase I Trial of Ruxolitinib in Patients with Chronic Myelomonocytic Leukemia (CMML)

scientific article

A Phase II Study of CLAG Regimen Combined With Imatinib Mesylate for Relapsed or Refractory Acute Myeloid Leukemia

scientific article

A Phase II Study to Determine the Safety and Efficacy of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase (IDO) Enzyme INCB024360 in Patients with Myelodysplastic Syndromes

scientific article published on 20 December 2018

A close association of autoimmune-mediated processes and autoimmune disorders with chronic myelomonocytic leukemia: observation from a single institution

scientific article published on 20 November 2014

A decade of progress in myelodysplastic syndrome with chromosome 5q deletion

scientific article published on 30 January 2018

A hypothesis for the pathogenesis of myelodysplastic syndromes: implications for new therapies.

scientific article

A model for prediction of FLT3-ITD and NPM1 (without FLT3-ITD) positivity in patients with newly diagnosed acute myeloid leukaemia

scientific article published on 6 July 2013

A multicenter, phase II study of maintenance azacitidine in older patients with acute myeloid leukemia in complete remission after induction chemotherapy.

scientific article

A multivariate analysis of the relationship between response and survival among patients with higher-risk myelodysplastic syndromes treated within azacitidine or conventional care regimens in the randomized AZA-001 trial ⬇️

scientific article published on April 12, 2013

A phase 2 study of lenalidomide monotherapy in patients with deletion 5q acute myeloid leukemia: Southwest Oncology Group Study S0605.

scientific article

A phase I study of oral ARRY-614, a p38 MAPK/Tie2 dual inhibitor, in patients with low or intermediate-1 risk myelodysplastic syndromes

scientific article

A phase I trial of 14-day continuous intravenous infusion mitoxantrone ⬇️

scientific article published on June 1, 1991

A phase I trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia.

scientific article

A phase II multicenter rabbit anti-thymocyte globulin trial in patients with myelodysplastic syndromes identifying a novel model for response prediction. ⬇️

scientific article

A randomized phase 2 study of PBPC mobilization by stem cell factor and filgrastim in heavily pretreated patients with Hodgkin's disease or non-Hodgkin's lymphoma

scientific article published on 01 September 2000

A randomized placebo-controlled trial of lisofylline in HLA-identical, sibling-donor, allogeneic bone marrow transplant recipients. The Lisofylline Marrow Transplant Study Group

scientific article published on 01 February 2000

ASXL1 frameshift mutations drive inferior outcomes in CMML without negative impact in MDS.

scientific article published on 27 November 2017

Aberrant overexpression of CD14 on granulocytes sensitizes the innate immune response in mDia1 heterozygous del(5q) MDS.

scientific article

Acanthocytosis associated with myelodysplasia

scientific article published on 01 October 1989

Acute nonlymphocytic leukemia after treatment of small cell lung cancer

scientific article published on 01 December 1986

Acute vascular ischemic events after cisplatin-based combination chemotherapy for germ-cell tumors of the testis

scientific article published on 01 July 1986

Advancements in the molecular pathogenesis of myelodysplastic syndrome.

scientific article published on March 2009

Advances in the management of myelofibrosis

scientific article

Age-related inflammatory bone marrow microenvironment induces ineffective erythropoiesis mimicking del(5q) MDS.

scientific article published on 16 November 2017

Alpha-interferon in the treatment of idiopathic myelofibrosis

scientific article published on April 1, 1992

Altered naive and memory CD4+ T-cell homeostasis and immunosenescence characterize younger patients with myelodysplastic syndrome

scientific article published on 12 March 2009

Alternative treatments for myelodysplastic syndromes.

scientific article

Amifostine protects normal tissues from paclitaxel toxicity while cytotoxicity against tumour cells is maintained

scientific article published on 01 September 1997

Amifostine protects primitive hematopoietic progenitors against chemotherapy cytotoxicity

scientific article published on 01 August 1996

Amifostine stimulates formation of multipotent and erythroid bone marrow progenitors

scientific article published on 01 October 1998

Amifostine: a tonic or toxin to myeloid progenitors

scientific article published on 01 December 2000

An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms.

scientific article published on September 2015

An international consortium proposal of uniform response criteria for myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in adults

scientific article published on 26 January 2015

An international data set for CMML validates prognostic scoring systems and demonstrates a need for novel prognostication strategies.

scientific article published on 31 July 2015

Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells.

scientific article published on September 1994

Applying synthetic lethality for the selective targeting of cancer.

scientific article published in October 2014

Assessment of ASC specks as a putative biomarker of pyroptosis in myelodysplastic syndromes: an observational cohort study.

scientific article published on 30 July 2018

Association of EZH2 protein expression by immunohistochemistry in myelodysplasia related neoplasms with mutation status, cytogenetics and clinical outcomes.

scientific article

Autoimmune diseases and myelodysplastic syndromes

scientific article

Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia

scientific article

Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study ⬇️

scientific article published on December 1, 2001

Between a rux and a hard place: evaluating salvage treatment and outcomes in myelofibrosis after ruxolitinib discontinuation

scientific article published on 30 November 2017

Biology and pathogenesis of the myelodysplastic syndromes

scientific article published on February 1, 1992

Biology and treatment of the 5q- syndrome.

scientific article published on February 2011

Bone marrow cellularity at day 14 is the most important predictive factor for response in patients with AML who require double-induction chemotherapy: Analysis from a large, single institution experience.

scientific article published on 22 December 2016

Burkitt's lymphoma in a homosexual

scientific article published on 01 May 1982

Challenges in myelodysplastic syndromes: raising awareness and promoting new insight in therapeutic options

scientific article published on 01 October 2008

Challenges of phase III trial design for novel treatments in diseases with no standard treatment: the AZA-001 myelodysplasia study model.

scientific article published on 27 October 2013

Cladribine, cytarabine, filgrastim, and mitoxantrone (CLAG-M) compared to standard induction in acute myeloid leukemia from myelodysplastic syndrome after azanucleoside failure.

scientific article published on 25 December 2013

Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study

scientific article

Combined treatment with lenalidomide and epoetin alfa in lower-risk patients with myelodysplastic syndrome.

scientific article

Comparative pharmacokinetic study of high-dose etoposide and etoposide phosphate in patients with lymphoid malignancy receiving autologous stem cell transplantation ⬇️

scientific article published on April 1, 2003

Comparison of clinical outcomes and prognostic utility of risk stratification tools in patients with therapy-related vs de novo myelodysplastic syndromes: a report on behalf of the MDS Clinical Research Consortium

scientific article

Comparison of four cytokine regimens for mobilization of peripheral blood stem cells: IL-3 alone and combined with GM-CSF or G-CSF

scientific article published on 01 February 1996

Comparison of risk stratification tools in predicting outcomes of patients with higher-risk myelodysplastic syndromes treated with azanucleosides.

scientific article published on 14 October 2015

Complete hematologic remission with oral etoposide in a patient with chronic myelomonocytic leukemia and profound dyserythropoiesis

scientific article published on 01 May 1994

Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes

scientific article published on 10 January 2011

Correlation of clinical response and response duration with miR-145 induction by lenalidomide in CD34+ cells from patients with del(5q) myelodysplastic syndrome ⬇️

scientific article published on August 28, 2012

Cost effectiveness of lenalidomide in the treatment of transfusion-dependent myelodysplastic syndromes in the United States

scientific article published on 01 December 2006

Cutaneous manifestations in CMML: Indication of disease acceleration or transformation to AML and review of the literature.

scientific article published on 22 July 2011

Cyclosporine inhibition of P-glycoprotein in chronic myeloid leukemia blast phase.

scientific article published in September 2002

Cytogenetic and molecular predictors of response in patients with myeloid malignancies without del[5q] treated with lenalidomide.

scientific article published on 5 March 2012

Cytogenetics and P-glycoprotein (PGP) are independent predictors of treatment outcome in acute myeloid leukemia (AML).

scientific article published in February 1996

Cytokine targets in the treatment of myelodysplastic syndromes.

scientific article published on November 2005

Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis

scientific article published on 03 April 2019

Deferasirox reduces serum ferritin and labile plasma iron in RBC transfusion-dependent patients with myelodysplastic syndrome

scientific article published on 30 April 2012

Deficient tumor-infiltrating T-lymphocyte response in malignant lymphoma: relationship to HLA expression and host immunocompetence

scientific article published on 01 March 1993

Deletion 5q MDS: molecular and therapeutic implications.

scientific article published on 16 October 2013

Deletions of Xp22.2 including PIG-A locus lead to paroxysmal nocturnal hemoglobinuria

scientific article published on 30 November 2010

Demonstration of additional benefit in adding lenalidomide to azacitidine in patients with higher-risk myelodysplastic syndromes

scientific article published on 01 January 2011

Diagnostic testing, treatment, cost of care, and survival among registered and non-registered patients with myelodysplastic syndromes ⬇️

scientific article published on August 17, 2011

Disparity in perceptions of disease characteristics, treatment effectiveness, and factors influencing treatment adherence between physicians and patients with myelodysplastic syndromes

scientific article published on 27 February 2014

Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation

scientific article published on 01 February 1997

Donor-derived constitutional chromosomal abnormalities after allogeneic hematopoietic cell transplantation: a single-center experience and a review of the literature.

scientific article

Durable long-term responses in patients with myelodysplastic syndromes treated with lenalidomide.

scientific article

ETV6 and signaling gene mutations are associated with secondary transformation of myelodysplastic syndromes to chronic myelomonocytic leukemia

scientific article published on June 2014

Efficacy and safety of lenalidomide in patients with myelodysplastic syndrome with chromosome 5q deletion.

scientific article published on April 2012

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

scientific article

Eltrombopag Use in Patients With Chronic Myelomonocytic Leukemia (CMML): A Cautionary Tale.

scientific article

Emerging immunosuppressive drugs in myelodysplastic syndromes.

scientific article

Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001-2004, using data from the NAACCR and SEER programs.

scientific article

Erythropoietin Receptor Signaling Is Membrane Raft Dependent ⬇️

scientific article published on April 3, 2012

Erythropoietin Receptor Signaling and Lipid Rafts.

scientific article published on 23 March 2017

Estimating the impact of new clinical trial proven cancer therapy and cancer chemoprevention on population mortality: the Karnofsky Memorial lecture.

scientific article published in December 2003

Evidence for Selective Benefit of Sequential Treatment With Hypomethylating Agents in Patients With Myelodysplastic Syndrome

scientific article published on 10 January 2017

Evolving applications of lenalidomide in the management of anemia in myelodysplastic syndromes.

scientific article published on December 2006

Evolving trends in the treatment of low-risk myelodysplastic syndromes: immunomodulation and beyond--9th European Hematology Association Congress Geneva, Switzerland, 10-13 June 2004

scientific article published on 01 June 2007

Expansion of effector memory regulatory T cells represents a novel prognostic factor in lower risk myelodysplastic syndrome.

scientific article published on 8 August 2012

Expression of the multidrug resistance gene product (P-glycoprotein) in myelodysplasia is associated with a stem cell phenotype ⬇️

scientific article published on May 1, 1991

Extended survival and reduced risk of AML progression in erythroid-responsive lenalidomide-treated patients with lower-risk del(5q) MDS

scientific article published on 01 December 2015

Extratesticular lesions: a radiological and pathological correlation

scientific article published on 01 May 1994

First-in-man study of CPX-351: a liposomal carrier containing cytarabine and daunorubicin in a fixed 5:1 molar ratio for the treatment of relapsed and refractory acute myeloid leukemia.

scientific article published on 31 January 2011

Fulminant Kaposi's sarcoma complicating long-term corticosteroid therapy.

scientific article

Functional hyposplenism

scientific article published on 01 August 1987

GM-CSF-dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia.

scientific article

Gastrostomy-biliary drainage in a patient with bile duct cancer: a basis for multimodality treatment

scientific article published on 01 July 1989

Genetic testing in the myelodysplastic syndromes: molecular insights into hematologic diversity.

scientific article

Genetically inspired prognostic scoring system (GIPSS) outperforms dynamic international prognostic scoring system (DIPSS) in myelofibrosis patients

scientific article published on 25 November 2018

Granulocytic sarcoma in myelodysplastic syndromes: clinical marker of disease acceleration

scientific article published on 01 February 1991

Hematopoietic progenitor cell content of bone marrow harvests: relative contributions of blood and bone marrow

scientific article published on 01 January 1994

Hematopoietic stimulation by amifostine and sodium phenylbutyrate: what is the potential in MDS? ⬇️

scientific article published on 01 May 1998

Heterogeneous expression of cytokines accounts for clinical diversity and refines prognostication in CMML

scientific article published on 19 July 2018

High rate of uncaptured myelodysplastic syndrome cases and an improved method of case ascertainment.

scientific article

Hyperleukocytosis complicating lonafarnib treatment in patients with chronic myelomonocytic leukemia.

scientific article published in February 2005

Hypoalbuminemia is an independent prognostic factor for overall survival in myelodysplastic syndromes ⬇️

scientific article published on August 1, 2012

Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening

scientific article

Identification of a risk dependent microRNA expression signature in myelodysplastic syndromes

scientific article

Immune Dysregulation in Myelodysplastic Syndrome ⬇️

scientific article published on January 26, 2010

Immunohistochemical pattern of p53 is a measure of TP53 mutation burden and adverse clinical outcome in myelodysplastic syndromes and secondary acute myeloid leukemia.

scientific article published on 14 April 2016

Immunomodulation in myelodysplastic syndromes.

scientific article published on January 2006

Immunomodulatory derivatives induce PU.1 down-regulation, myeloid maturation arrest, and neutropenia.

scientific article published on 25 November 2009

Immunomodulatory drugs.

scientific article

Immunosuppressive Therapy: Exploring an Underutilized Treatment Option for Myelodysplastic Syndrome

scientific article

Impact of Specimen Heterogeneity on Biomarkers in Repository Samples from Patients with Acute Myeloid Leukemia: A SWOG Report

scientific article published on 27 November 2017

Impact of TP53 mutation variant allele frequency on phenotype and outcomes in myelodysplastic syndromes.

scientific article

Impact of baseline cytogenetic findings and cytogenetic response on outcome of high-risk myelodysplastic syndromes and low blast count AML treated with azacitidine

scientific article

Impact of tobacco usage on disease outcome in myelodysplastic syndromes.

scientific article published on 7 April 2015

Improved intra-array and interarray normalization of peptide microarray phosphorylation for phosphorylome and kinome profiling by rational selection of relevant spots

scientific article published on 26 May 2016

Incidence of the myelodysplastic syndromes using a novel claims-based algorithm: high number of uncaptured cases by cancer registries.

scientific article

Induction of myelodysplasia by myeloid-derived suppressor cells.

scientific article

Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity

scientific article published on 06 December 2018

Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitors.

scientific article published on 29 August 2006

Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.

scientific article published on 12 May 2008

Intrapatient functional clonality deconvoluted by coupling intracellular flow cytometry and next-generation sequencing in human leukemia

scientific article

Introduction: myeloproliferative disorders

scientific article published on 01 August 1995

JAK2-V617F-mediated signalling is dependent on lipid rafts and statins inhibit JAK2-V617F-dependent cell growth

scientific article published on 15 November 2012

KG-1 and KG-1a model the p15 CpG island methylation observed in acute myeloid leukemia patients.

scientific article

Lenalidomide (Revlimid, CC-5013) in myelodysplastic syndromes: Is it any good?

scientific article published on 01 March 2006

Lenalidomide (Revlimid, CC-5013) in myelodysplastic syndromes: is it any good?

scientific article

Lenalidomide Stabilizes the Erythropoietin Receptor by Inhibiting the E3 Ubiquitin Ligase RNF41.

scientific article published on 06 April 2016

Lenalidomide Treatment for Lower Risk Nondeletion 5q Myelodysplastic Syndromes Patients Yields Higher Response Rates When Used Before Azacitidine.

scientific article

Lenalidomide does not increase AML progression risk in RBC transfusion-dependent patients with Low- or Intermediate-1-risk MDS with del(5q): a comparative analysis.

scientific article published on 21 December 2012

Lenalidomide for treatment of myelodysplastic syndromes.

scientific article published on January 2012

Lenalidomide for treatment of myelodysplastic syndromes: current status and future directions.

scientific article published on April 2010

Lenalidomide in myelodysplastic syndromes.

scientific article published in April 2008

Lenalidomide induces lipid raft assembly to enhance erythropoietin receptor signaling in myelodysplastic syndrome progenitors

scientific article

Lenalidomide--a transforming therapeutic agent in myelodysplastic syndromes.

scientific article

Lenalidomide--the phoenix rises.

scientific article published in November 2007

Lenalidomide: Myelodysplastic syndromes with del(5q) and beyond.

scientific article

Lenalidomide: from bench to bedside (part 1)

scientific article published on 01 December 2006

Lenalidomide: targeted anemia therapy for myelodysplastic syndromes.

scientific article

Limited erythropoietic response to combined treatment with recombinant human interleukin 3 and erythropoietin in myelodysplastic syndrome

scientific article published on 01 January 1999

Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks

scientific article published on 15 July 2019

Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis

scientific article

Low itraconazole serum concentrations following administration of itraconazole suspension to critically ill allogeneic bone marrow transplant recipients

scientific article published on 01 February 1995

Lung cancer after exposure to radon daughters

scientific article published on 01 September 1984

Lung cancer in Hodgkin's disease: association with previous radiotherapy

scientific article published on 01 February 1985

Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes

scientific article published on 01 January 2020

Malignant hypercalcemia. The choice of therapy

scientific article published on 01 March 1991

Management of RBC-transfusion dependence.

scientific article published on January 2007

Management of lower-risk myelodysplastic syndromes: the art and evidence.

scientific article published on June 2011

Mast cell growth factor (c-kit ligand) restores growth of multipotent progenitors in myelodysplastic syndrome

scientific article published on 01 May 1994

Metastatic giant-cell bone tumor in a man positive for HIV

scientific article published on 01 February 1988

Methyltransferase inhibitors: changing the treatment algorithm for myelodysplastic syndromes.

scientific article

Molecular pathogenesis of myelodysplastic syndromes with deletion 5q

scientific article published on 16 January 2019

Molecular predictors of response in patients with myeloid neoplasms treated with lenalidomide.

scientific article published on 18 August 2016

Monoclonal gammopathy of undetermined significance disguised as chronic neutrophilic leukemia.

scientific article

Monocyte subset analysis accurately distinguishes CMML from MDS and is associated with a favorable MDS prognosis

scientific article published on 3 February 2017

Multidrug resistance in acute leukemia: a conserved physiologic function

scientific article published on September 1, 1992

Multikinase inhibitors for treating high-risk myelodysplastic syndromes: can this be brought into clinical practice?

scientific article

Multiple mechanisms deregulate EZH2 and histone H3 lysine 27 epigenetic changes in myeloid malignancies.

scientific article published on 14 March 2013

Mutational correlates of response to hypomethylating agent therapy in acute myeloid leukemia.

scientific article published on 14 July 2016

Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A.

scientific article

Mutations of e3 ubiquitin ligase cbl family members constitute a novel common pathogenic lesion in myeloid malignancies.

scientific article

Mutations of the myeloid transcription factor CEBPA are not associated with the blast crisis of chronic myeloid leukaemia.

scientific article published on May 2006

Myelodysplastic Syndromes in Adolescent Young Adults: One Institution's Experience.

scientific article published on August 2016

Myelodysplastic syndromes

scientific article published on 01 August 1989

Myelodysplastic syndromes.

scientific article

Myelodysplastic syndromes: introduction

scientific article published on 01 February 1992

Naive T-cells in myelodysplastic syndrome display intrinsic human telomerase reverse transcriptase (hTERT) deficiency.

scientific article

New approaches to the treatment of myelodysplasia.

scientific article

New therapeutics for myelodysplastic syndromes.

scientific article published on 07 September 2012

Non-Hodgkin's lymphoma of the gastrointestinal tract: an analysis of clinical and pathologic features affecting outcome ⬇️

scientific article published on July 1, 1988

Non-P-glycoprotein drug export mechanisms of multidrug resistance.

scientific article published on October 1997

Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies

scientific article published on 19 August 2010

Novel therapeutic approach to improve hematopoiesis in low risk MDS by targeting MDSCs with the Fc-engineered CD33 antibody BI 836858

scientific article published on 18 January 2017

On the use of lonafarnib in myelodysplastic syndrome and chronic myelomonocytic leukemia.

scientific article published on 12 June 2008

Opportunities for Trisenox (arsenic trioxide) in the treatment of myelodysplastic syndromes.

scientific article

Outcome of azacitidine treatment in patients with therapy-related myeloid neoplasms with assessment of prognostic risk stratification models.

scientific article published on 16 January 2013

Outcome of patients with low-risk and intermediate-1-risk myelodysplastic syndrome after hypomethylating agent failure: a report on behalf of the MDS Clinical Research Consortium

scientific article

Outcome of patients with myelodysplastic syndromes in the Veterans Administration population.

scientific article published on 14 April 2009

Outcomes after induction chemotherapy in patients with acute myeloid leukemia arising from myelodysplastic syndrome.

scientific article

Outcomes of patients with myelodysplastic syndromes who achieve stable disease after treatment with hypomethylating agents

scientific article published on 22 December 2015

PP2A: The Achilles Heal in MDS with 5q Deletion

scientific article

Paroxysmal nocturnal hemoglobinuria and concurrent JAK2(V617F) mutation.

scientific article published on 23 March 2012

Perceptions of disease state, treatment outcomes, and prognosis among patients with myelodysplastic syndromes: results from an internet-based survey

scientific article published on 8 April 2011

Persistent malignant stem cells in del(5q) myelodysplasia in remission

scientific article

Pharmacological differentiation and anti-apoptotic therapy in myelodysplastic syndromes.

scientific article

Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TLK199 tablets), a novel glutathione analog prodrug, in patients with myelodysplastic syndrome.

scientific article

Phase 1 study of PTK787/ZK 222584, a small molecule tyrosine kinase receptor inhibitor, for the treatment of acute myeloid leukemia and myelodysplastic syndrome

scientific article published on 01 June 2006

Phase 2 study of the lenalidomide and azacitidine combination in patients with higher-risk myelodysplastic syndromes ⬇️

scientific article published on August 22, 2012

Phase I Clinical Trial of Selinexor in Combination with Daunorubicin and Cytarabine in Previously Untreated Poor-Risk Acute Myeloid Leukemia

scientific article published on 21 October 2019

Phase I clinical trial of oral rigosertib in patients with myelodysplastic syndromes.

scientific article published on 21 June 2013

Phase I clinical, pharmacokinetic, and pharmacodynamic study of the Akt-inhibitor triciribine phosphate monohydrate in patients with advanced hematologic malignancies

scientific article

Phase I/II study of the P-glycoprotein modulator PSC 833 in patients with acute myeloid leukemia.

scientific article published in March 2001

Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia

scientific article published on 01 September 1993

Phase II clinical study of erlotinib for treatment of myelodysplastic syndromes.

scientific article

Phase II pilot study of oral dasatinib in patients with higher-risk myelodysplastic syndrome (MDS) who failed conventional therapy ⬇️

scientific article published on December 27, 2012

Poor Outcome of Patients With Myelodysplastic Syndrome After Azacitidine Treatment Failure

scientific article published on 17 September 2013

Post-transplantation T-cell lymphoblastic lymphoma

scientific article published on 01 January 1988

Preclinical investigations of drug resistance

scientific article published on January 1, 1995

Predictive factors of response and survival among chronic myelomonocytic leukemia patients treated with azacitidine

scientific article published on 12 February 2013

Predominance of chromosome 5 deletions in myeloid neoplasia associated with solid tumors managed by surgical excision.

scientific article

Pretransplantation 5-azacitidine in high-risk myelodysplastic syndrome

scientific article published on 15 February 2014

Prevalence and prognostic significance of allelic imbalance by single-nucleotide polymorphism analysis in low-risk myelodysplastic syndromes

scientific article published on 18 July 2007

Primary brain lymphoma in the immunocompetent host: relation to Epstein-Barr virus.

scientific article published in September 1990

Problematic WHO reclassification of myelodysplastic syndromes. Members of the International MDS Study Group.

scientific article published in October 2000

Prognostic factors and risk models in myelodysplastic syndromes.

scientific article published on September 2013

Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies

scientific article

Prognostic significance of NPM1 mutations in the absence of FLT3-internal tandem duplication in older patients with acute myeloid leukemia: a SWOG and UK National Cancer Research Institute/Medical Research Council report

scientific article

Proposal for a new risk model in myelodysplastic syndrome that accounts for events not considered in the original International Prognostic Scoring System

scientific article

Randomized, dose-escalation study of the p38α MAPK inhibitor SCIO-469 in patients with myelodysplastic syndrome.

scientific article published on 11 September 2012

Ranitidine-induced granulocytopenia: recurrence with cimetidine administration

scientific article published on 01 April 1988

Rational Approaches to Design of Therapeutics Targeting Molecular Markers ⬇️

scientific article published on January 1, 2001

Recurrent genetic defects on chromosome 5q in myeloid neoplasms.

scientific article published on 23 December 2016

Recurrent hemorrhagic choroidal detachment associated with disseminated intravascular coagulation

scientific article published on 01 February 1992

Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes.

scientific article

Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase

scientific article published on 28 December 2010

Remitting activity of lenalidomide in treatment-induced myelodysplastic syndrome

scientific article published on 29 March 2007

Reply to Goel et al. 'TP53 mutation allele-burden and disease outcome in MDS/AML'

scientific article published on 14 October 2016

Report of an unusual lymphoma arising from parafollicular B-lymphocytes (PBLs) or so-called "monocytoid" lymphocytes

scientific article published on 01 January 1987

Report of the relapsed/refractory cohort of SWOG S0919: A phase 2 study of idarubicin and cytarabine in combination with pravastatin for acute myelogenous leukemia (AML).

scientific article published on 31 January 2018

Reversal of T-cell tolerance in myelodysplastic syndrome through lenalidomide immune modulation.

scientific article published on 23 December 2011

Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML.

scientific article published on 2 June 2017

Role of lenalidomide in the treatment of myelodysplastic syndromes.

scientific article

Role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia.

scientific article published on June 1996

S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes

scientific article published on 08 February 2019

SOHO State of the Art Update and Next Questions: Biology and Treatment of Myelodysplastic Syndromes.

scientific article

SOHO State of the Art and Next Questions: Management of Myelodysplastic Syndromes With Deletion 5q

scientific article published on 30 July 2018

STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients

scientific article

STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia

scientific article published on 2 August 2012

SWOG0919: a Phase 2 study of idarubicin and cytarabine in combination with pravastatin for relapsed acute myeloid leukaemia

scientific article

Salvage chemotherapy regimens for acute myeloid leukemia: Is one better? Efficacy comparison between CLAG and MEC regimens.

scientific article published on 24 November 2010

Selective exclusion by the polyamine transporter as a mechanism for differential radioprotection of amifostine derivatives.

scientific article

Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia

scientific article

Seroreactivity to LGL leukemia-specific epitopes in aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria: results of a bone marrow failure consortium study

scientific article published on 2 March 2012

Severe hypoalbuminemia at day 90 predicts worse nonrelapse mortality and overall survival after allogeneic hematopoietic stem cell transplantation for acute myelogenous leukemia and myelodysplastic syndrome.

scientific article published on 22 July 2010

Short- and long-term benefits of lenalidomide treatment in patients with lower-risk del(5q) myelodysplastic syndromes

scientific article

Sotatercept with long-term extension for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes: a phase 2, dose-ranging trial

scientific article published on 10 January 2018

Spinal cord toxicity complicating treatment with cisplatin and etoposide

scientific article published on 01 June 1990

Src family kinases promote AML cell survival through activation of signal transducers and activators of transcription (STAT)

scientific article published on 07 January 2008

Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations

scientific article

Stimulation of hematopoiesis by amifostine in patients with myelodysplastic syndrome.

scientific article

Subsequent primary malignancies and acute myelogenous leukemia transformation among myelodysplastic syndrome patients treated with or without lenalidomide.

scientific article published on 20 April 2016

Suppressor of cytokine signaling-3 is overexpressed in erythroid precursors of myelodysplastic syndrome

scientific article published on 20 July 2006

T-cell large granular lymphocyte proliferation in myelodysplastic syndromes: Clinicopathological features and prognostic significance

scientific article published on 17 February 2016

TP53 and IDH2 Somatic Mutations Are Associated With Inferior Overall Survival After Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndrome

scientific article published on 16 June 2017

TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes.

scientific article published on 25 September 2015

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

scientific article published on 11 January 2019

TP53 suppression promotes erythropoiesis in del(5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients

scientific article published on 16 September 2013

Targeted resequencing analysis of 31 genes commonly mutated in myeloid disorders in serial samples from myelodysplastic syndrome patients showing disease progression.

scientific article published on 20 May 2015

Targeted therapies in myelodysplastic syndrome.

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Telomere length in myelodysplastic syndromes.

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The 5q- Syndrome: Biology and Treatment ⬇️

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The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype ⬇️

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The Treatment Landscape of Myelofibrosis Before and After Ruxolitinib Approval.

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The central role of inflammatory signaling in the pathogenesis of myelodysplastic syndromes

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The clinical management of chronic myelomonocytic leukemia

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The effects of continued azacitidine treatment cycles on response in higher risk patients with myelodysplastic syndromes: an update.

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The effects of delta9-tetrahydrocannabinol and cannabidiol on the metabolism of gonadal steroids in the rat ⬇️

scientific article published on May 1, 1977

The efficacy of current prognostic models in predicting outcome of patients with myelodysplastic syndromes at the time of hypomethylating agent failure

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The hematopoietic growth factors in the myelodysplastic syndromes.

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The impact of lenalidomide exposure on response and outcomes in patients with lower-risk myelodysplastic syndromes and del(5q)

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The incidence of contrast medium induced acute tubular necrosis following arteriography

scientific article published on 01 January 1981

The myelodysplastic syndromes: biology and implications for management ⬇️

scientific article published on August 1, 1990

The prognostic significance of IRF8 transcripts in adult patients with acute myeloid leukemia

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The prognostic value of circulating myeloblasts in patients with myelodysplastic syndromes

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The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes

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The role of p53 in myelodysplastic syndromes and acute myeloid leukemia: molecular aspects and clinical implications.

scientific article published on 14 December 2016

The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in small-cell lung cancer.

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Thrombosis associated with procainamide-induced lupus anticoagulant

scientific article published on 01 January 1989

Treatment of deletion 5q acute myeloid leukemia with lenalidomide

scientific article published on 18 January 2007

Treatment with low-dose oral etoposide in patients with myelodysplastic syndromes ⬇️

scientific article published on January 1, 1998

Tumor lysis syndrome complicating treatment of chronic lymphocytic leukemia with fludarabine phosphate

scientific article published on 01 September 1990

Uncommon of the uncommon: low-grade myelodysplastic syndrome evolving into chronic myelogenous leukemia

scientific article published on 13 December 2010

Underreporting of Myeloid Malignancies by United States Cancer Registries ⬇️

scientific article published on January 11, 2012

Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype

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Unusual concurrence of T-cell large granular lymphocytic leukemia with Franklin disease (gamma heavy chain disease) manifested with massive splenomegaly ⬇️

scientific article published on July 9, 2012

Update on the pharmacotherapy for myelodysplastic syndromes.

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Urine Galactomannan-to-Creatinine Ratio for Detection of Invasive Aspergillosis in Patients with Hematological Malignancies

scientific article published on 23 December 2015

Validation of International Working Group response criteria in higher-risk myelodysplastic syndromes: A report on behalf of the MDS Clinical Research Consortium

scientific article published on 22 December 2020

Validation of the IPSS-R in lenalidomide-treated, lower-risk myelodysplastic syndrome patients with del(5q).

scientific article published on 29 August 2014

Validation of the Lower-Risk MD Anderson Prognostic Scoring System for Patients With Myelodysplastic Syndrome.

scientific article published on June 2015

Validation of the MD Anderson Prognostic Risk Model for patients with myelodysplastic syndrome.

scientific article published on 28 September 2011

Validation of the revised International Prognostic Scoring System in treated patients with myelodysplastic syndromes.

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Vascular Endothelial Growth Factor Signaling Pathway as an Emerging Target in Hematologic Malignancies ⬇️

scientific article published on January 1, 2001

Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes.

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WT1 vaccination in AML and MDS: A pilot trial with synthetic analog peptides

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When clinical heterogeneity exceeds genetic heterogeneity: thinking outside the genomic box in chronic myelomonocytic leukemia.

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miR-21 mediates hematopoietic suppression in MDS by activating TGF-β signaling

scientific article published on 6 February 2013

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