Search filters

List of works by Eric E Swayze

A Constrained Tricyclic Nucleic Acid Analogue of α-l-LNA: Investigating the Effects of Dual Conformational Restriction on Duplex Thermal Stability ⬇️

scientific article published on 04 September 2013

Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAs

scientific article

An Exocyclic Methylene Group Acts As a Bioisostere of the 2′-Oxygen Atom in LNA ⬇️

scientific article published on October 27, 2010

Antibacterial activity of quinolone–Macrocycle conjugates ⬇️

scientific article published on May 19, 2003

Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7

article

Disaccharide mimetics of the aminoglycoside antibiotic neamine

scientific article

Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease

article

Improved synthesis and biological evaluation of an acyclic thiosangivamycin active against human cytomegalovirus

scientific article published on July 1, 1992

Insights from Crystal Structures into the Opposite Effects on RNA Affinity Caused by the S- and R-6′-Methyl Backbone Modifications of 3′-Fluoro Hexitol Nucleic Acid ⬇️

scientific article published on December 29, 2011

Lipid Nanoparticles Improve Activity of Single-Stranded siRNA and Gapmer Antisense Oligonucleotides in Animals ⬇️

scientific article published on May 2, 2013

Structural requirements for hybridization at the 5′-position are different in α-l-LNA as compared to β-d-LNA ⬇️

scientific article published on November 11, 2011

Structure Activity Relationships of α-L-LNA Modified Phosphorothioate Gapmer Antisense Oligonucleotides in Animals ⬇️

scientific article published on September 18, 2012

Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: A synergistic hydrophobic effect against resistant bacteria ⬇️

scientific article published on September 19, 2010

Synthesis and Biophysical Properties of Constrained d-Altritol Nucleic Acids (cANA) ⬇️

scientific article published on August 13, 2013

Synthesis and biophysical characterization of R-6′-Me-α-l-LNA modified oligonucleotides ⬇️

scientific article published on December 31, 2010

Synthesis and biophysical evaluation of 3′-Me-α-l-LNA – Substitution in the minor groove of α-l-LNA duplexes ⬇️

scientific article published on June 30, 2011

Synthesis of cis- and trans-α-l-[4.3.0]Bicyclo-DNA Monomers for Antisense Technology: Methods for the Diastereoselective Formation of Bicyclic Nucleosides ⬇️

scientific article published on September 4, 2013

Synthesis of linked carbohydrates and evaluation of Their binding for 16S RNA by mass spectrometry ⬇️

scientific article published on November 17, 2003

Synthesis, Duplex Stabilization and Structural Properties of a Fluorinated Carbocyclic LNA Analogue ⬇️

scientific article published on November 28, 2012

Synthesis, Improved Antisense Activity and Structural Rationale for the Divergent RNA Affinities of 3′-Fluoro Hexitol Nucleic Acid (FHNA and Ara-FHNA) Modified Oligonucleotides ⬇️

scientific article published on September 22, 2011

Trisaccharide mimetics of the aminoglycoside antibiotic neomycin

scientific article

ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy ⬇️

scientific article published on 09 August 2013

Paulina is supported by:

About Paulina

Help