Search filters

List of works by Xandra O. Breakefield

A chimeric fusion protein of cytochrome CYP4B1 and green fluorescent protein for detection of pro-drug activating gene delivery and for gene therapy in malignant glioma

scientific article

A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study

scientific article

A comparison of the proliferative and replicative life span kinetics of cell cultures derived from monozygotic twins

scientific article published on 01 January 1981

A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons

scientific article published in September 1988

A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons

scientific article published in 1988

A genetic linkage map of human chromosome 9q

scientific article published on November 1, 1992

A heteroplasmic mitochondrial complex I gene mutation in adult-onset dystonia

scientific article published on 17 May 2003

A highly sensitive assay for monitoring the secretory pathway and ER stress

scientific article

A major locus for myoclonus-dystonia maps to chromosome 7q in eight families

scientific article

A mutation in the Norrie disease gene (NDP) associated with X-linked familial exudative vitreoretinopathy

scientific article

A new RFLP for D18S3(B74) an anonymous genomic clone localized to 18p113.

scientific article

A novel 'piggyback' packaging system for herpes simplex virus amplicon vectors

scientific article published on October 1996

A novel imaging-compatible sciatic nerve schwannoma model ⬇️

scientific article published on November 24, 2010

A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe

scientific article published on March 2004

A secreted luciferase for ex vivo monitoring of in vivo processes

scientific article published on 20 January 2008

A syndrome of autosomal dominant alternating hemiplegia: clinical presentation mimicking intractable epilepsy; chromosomal studies; and physiologic investigations

scientific article (publication date: December 1992)

Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A

scientific article

Adenoassociated virus serotype 9-mediated gene therapy for x-linked adrenoleukodystrophy

scientific article

Adult onset idiopathic torsion dystonia is excluded from the DYT 1 region (9q34) in a Swedish family ⬇️

scientific article published on August 1, 1995

Advances in therapeutic applications of extracellular vesicles

scientific article published on 01 May 2019

Altered nerve growth factor in fibroblasts from patients with familial dysautonomia ⬇️

scientific article published on February 1, 1980

Alzheimer's Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

Alzheimer's Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

scientific article published on 01 December 2018

An experimental model of retrovirus gene therapy for malignant brain tumors

scientific article published on July 1993

Analysis of MAOA mutations in humans.

scientific article published on January 1995

Analysis of extracellular mRNA in human urine reveals splice variant biomarkers of muscular dystrophies

scientific article published in Nature Communications

Animal models for drug discovery in dystonia ⬇️

scientific article published on January 1, 2008

Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase

scientific article published on September 1, 1994

Are MAO-A deficiency states in the general population and in putative high-risk populations highly uncommon? ⬇️

scientific article published on January 1, 1998

Artifactual presence of beta-nerve growth factor in adult mouse brain

scientific article published on 01 March 1984

Association of a missense change in the D2 dopamine receptor with myoclonus dystonia

scientific article

Astrocytes retrovirally transduced with BDNF elicit behavioral improvement in a rat model of Parkinson's disease

scientific article published in September 1995

Authentic and artifactual detection of the E. coli lacZ gene product in the rat brain by histochemical methods

scientific article published on December 1, 1992

Autocrine differentiation of PC12 cells mediated by retroviral vectors.

scientific article published in January 1990

BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles.

scientific article published on 23 July 2013

Banl RFLP atAK1locus (9q34) ⬇️

scientific article published on October 25, 1991

Benefits and risks of hosting animal cells in the human brain.

scientific article published on September 1997

Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model

scientific article

Biochemical and cellular analysis of human variants of the DYT1 dystonia protein, TorsinA/TOR1A

scientific article

Biochemistry and genetics of monoamine oxidase

scientific article

Bone marrow transplantation restores immune system function and prevents lymphoma in Atm-deficient mice

scientific article published on 25 March 2004

Brain tumor microvesicles: insights into intercellular communication in the nervous system

scientific article published on 08 May 2011

CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease.

scientific article

Cathechol‐O‐methyltransferase activity in cultured human skin fibroblasts from controls and patients with dystonia musculorum deformans ⬇️

scientific article published on 01 January 1981

Cell Biology and Signaling

scholarly article

Cell-mediated delivery of neurotrophic factors and neuroprotection in the neostriatum and substantia nigra

scientific article published on 01 January 1995

Characterization and mapping of the mouse NDP (Norrie disease) locus (Ndp).

scientific article published on February 1996

Characterization of a YAC containing part or all of the Norrie disease locus

scientific article

Characterization of a mutation within the NDP gene in a family with a manifesting female carrier

scientific article

Characterization of monoamine oxidase activity during early stages of quail embryogenesis

scientific article published on 01 January 1983

Characterization of single microvesicles in plasma from glioblastoma patients

scientific article published on 01 May 2019

Chemical enhancement of torsinA function in cell and animal models of torsion dystonia

scientific article

Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma

scientific article

Clinical and genetic evaluation of a family with a mixed dystonia phenotype from south tyrol ⬇️

scientific article published on 01 September 1998

Clinical findings of a myoclonus-dystonia family with two distinct mutations

scientific article published on 01 October 2002

Clinical-genetic spectrum of primary dystonia

scientific article published on 01 January 1998

Co-factor insufficiency in dystonia-parkinsonian syndrome

scientific article published on 01 November 1994

Coding and noncoding landscape of extracellular RNA released by human glioma stem cells.

scientific article published on 26 October 2017

Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo

scientific article

Combined HSV-1 recombinant and amplicon piggyback vectors: replication-competent and defective forms, and therapeutic efficacy for experimental gliomas

scientific article

Combining CNS transplantation and gene transfer

scientific article

Comparative efficacy of expression of genes delivered to mouse sensory neurons with herpes virus vectors.

scientific article published in January 1994

Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain.

scientific article published on December 1995

Correction of acid beta-galactosidase deficiency in GM1 gangliosidosis human fibroblasts by retrovirus vector-mediated gene transfer: higher efficiency of release and cross-correction by the murine enzyme

scientific article

Correction: Dopa-Responsive Dystonia: Functional Analysis of Single Nucleotide Substitutions within the 5’ Untranslated Region

Correction: Stochastic Model of Tsc1 Lesions in Mouse Brain

scientific article published on 7 November 2013

Correction: dtorsin, the Drosophila Ortholog of the Early-Onset Dystonia TOR1A (DYT1), Plays a Novel Role in Dopamine Metabolism

scientific article published on 31 October 2011

Creation of transgenic mice that overexpress monoamine oxidase-B neuronally

scientific article published on May 1992

Critical issues in gene therapy for neurologic disease

scientific article

DNA polymorphisms for the nerve growth factor receptor gene exclude its role in familial dysautonomia

article

De Novo Mutations (GAG Deletion) in the DYT1 Gene in Two Non-Jewish Patients with Early-onset Dystonia ⬇️

scientific article published on July 1, 1998

Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells

scientific article published on 14 January 2016

Degradation of fibrillar collagen in a human melanoma xenograft improves the efficacy of an oncolytic herpes simplex virus vector

scientific article published in March 2006

Delivery of Therapeutic Proteins via Extracellular Vesicles: Review and Potential Treatments for Parkinson's Disease, Glioma, and Schwannoma.

scientific article published on 26 March 2016

Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption

scientific article

Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2.

scientific article

Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients

scientific article

Developmental patterns of torsinA and torsinB expression

scientific article

Dexamethasone selectively increases monoamine oxidase type a in human skin fibroblasts ⬇️

scientific article published on February 12, 1981

Differences in A and B forms of monoamine oxidase revealed by limited proteolysis and peptide mapping ⬇️

scientific article published on October 25, 1979

Differences in monoamine oxidase activity between cultured noradrenergic and cholinergic sympathetic neurons

scientific article published on 01 March 1987

Differences in the Structure of A and B Forms of Human Monoamine Oxidase ⬇️

scientific article published on 01 August 1981

Differences in the structures of monoamine oxidases A and B in rat clonal cell lines.

scientific article published in February 1983

Diffusible cytotoxic metabolites contribute to the in vitro bystander effect associated with the cyclophosphamide/cytochrome P450 2B1 cancer gene therapy paradigm.

scientific article published in October 1995

Dinucleotide repeat polymorphism (D16S285) on human chromosome 16

scientific article

Dinucleotide repeat polymorphism for the hexabrachion gene (HXB) on chromosome 9q32–34 ⬇️

scientific article published on May 1, 1992

Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain.

scientific article

Discovery and Verification of Extracellular miRNA Biomarkers for Non-invasive Prediction of Pre-eclampsia in Asymptomatic Women

scientific article published on 01 May 2020

Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1.

scientific article published on 11 December 2017

Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly

scientific article published in February 2018

Distinct forms of monoamine oxidase expressed in hepatoma and HeLa cells in culture ⬇️

scientific article published on January 1, 1979

Distribution and ultrastructural localization of torsinA immunoreactivity in the human brain

scientific article published in October 2003

Distribution of the mRNAs encoding torsinA and torsinB in the normal adult human brain

scientific article published on November 1999

Dopa-responsive dystonia: functional analysis of single nucleotide substitutions within the 5' untranslated GCH1 region

scientific article

Dopamine release is impaired in a mouse model of DYT1 dystonia

scientific article

Dopamine transmission in DYT1 dystonia

scientific article published on January 1, 2004

Dopamine transmission in DYT1 dystonia: a biochemical and autoradiographical study

scientific article published in August 2002

Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2

scientific article

Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway

scientific article published on 24 August 2009

Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter

scientific article published on 09 January 2014

Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors.

scientific article published in December 2002

Dystonia in Ashkenazi Jews: clinical characterization of a founder mutation

scientific article published on 01 November 1994

Dystonia-causing mutant torsinA inhibits cell adhesion and neurite extension through interference with cytoskeletal dynamics

scientific article

Effect of riboflavin on monoamine oxidase activity in cultured neuroblastoma cells

scientific article published on 01 December 1981

Effects of biologically delivered NGF, BDNF and bFGF on striatal excitotoxic lesions

scientific article published on April 1993

Effects of genetic variations in the dystonia protein torsinA: identification of polymorphism at residue 216 as protein modifier

scientific article published on 14 March 2006

Electrophoretic analysis of 3H-pargyline-labeled monoamine oxidases A and B from human and rat cells.

scientific article published in March 1980

Electrophoretic characterization of monoamine oxidase by [3H]pargyline binding in rat hepatoma cells with A and B activity ⬇️

scientific article published on 01 July 1979

Elevation of neuronal MAO-B activity in a transgenic mouse model does not increase sensitivity to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

scientific article published on 01 September 1994

Emerging roles of extracellular vesicles in the nervous system

scientific article

Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.

scientific article published on 12 January 2018

Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells

scientific article

Epsilon-sarcoglycan mutations found in combination with other dystonia gene mutations

scientific article (publication date: November 2002)

Evaluation of the role of the D2 dopamine receptor in myoclonus dystonia.

scientific article published in March 2000

Exclusion of autosomal dominant dystonia gene from large regions of chromosomes 11p, 13q, and 21q by multi-point linkage analysis

scientific article published on 01 January 1987

Exclusion of chromosome regions 6p12 and 15q11, but not chromosome region 7p11, in a German family with autosomal dominant congenital nystagmus

scientific article published on 01 November 1998

Exclusion of familial dysautonomia from more than 60% of the genome

scientific article

Exogenous loading of extracellular vesicles, virus-like particles, and lentiviral vectors with supercharged proteins

scientific article published in 2022

Exosome-based liquid biopsies in cancer: opportunities and challenges

Exosome/microvesicle content is altered in leucine-rich repeat kinase 2 mutant induced pluripotent stem cell-derived neural cells

scientific article published on 30 November 2019

Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene

scientific article published in August 1994

Exploring Predictors of Response to Dacomitinib in EGFR-Amplified Recurrent Glioblastoma

scientific article published on 08 June 2020

Expression of human ATM cDNA in Atm-deficient mouse brain mediated by HSV-1 amplicon vector

scientific article published on 30 June 2006

Expression of monoamine oxidase A and B activities in mouse cybrids and hybrids

scientific article published on 01 January 1981

Expression of the early-onset torsion dystonia gene (DYT1) in human brain.

scientific article

Extensive conjugation of dopamine (3,4-dihydroxyphenethylamine) metabolites in cultured human skin fibroblasts and rat hepatoma cells ⬇️

scientific article published on October 15, 1978

Extracellular RNA mediates and marks cancer progression

scientific article published on 28 April 2014

Extracellular Vesicle-Mediated Bilateral Communication between Glioblastoma and Astrocytes

scientific article published on 21 November 2020

Extracellular Vesicles and Their Convergence with Viral Pathways ⬇️

scientific article published on July 25, 2012

Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity

scientific article published on 24 March 2016

Extracellular Vesicles: Composition, Biological Relevance, and Methods of Study

scientific article published on 26 June 2015

Extracellular Vesicles: Unique Intercellular Delivery Vehicles

scientific article published on 12 December 2016

Extracellular vesicles and intercellular communication within the nervous system

scientific article published on April 2016

Extracellular vesicles derived from human vestibular schwannomas associated with poor hearing damage cochlear cells

scientific article published on 18 May 2016

Extracellular vesicles: biology and emerging therapeutic opportunities.

scientific article published on 15 April 2013

Extracellular vesicles: emerging targets for cancer therapy.

scientific article published on 03 April 2014

FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice

scientific article

FGF-2 regulation of neurogenesis in adult hippocampus after brain injury

scientific article published on 24 April 2001

Fine localization of the torsion dystonia gene (DYT1) on human chromosome 9q34: YAC map and linkage disequilibrium

scientific article

Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo

scientific article published on 01 July 1999

Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: implications for noninvasive imaging of transgene expression

scientific article published on June 1999

Gene Delivery to the Nervous System: NINDS Workshop on Gene Delivery to the Nervous System Washington, DC, 12-13 November 2007

Gene Transfer into Hepatocytes Mediated by Helper Virus-Free HSV/AAV Hybrid Vectors ⬇️

scientific article published on December 1, 1997

Gene delivery into the brain using virus vectors

scientific article published in March 1993

Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line

scientific article published on November 1990

Gene delivery to mouse sensory neurons with herpes simplex virus: a model for postherpetic neuralgia and its treatment?

scientific article published in December 1995

Gene delivery to the nervous system

scientific article published on April 2008

Gene for monoamine oxidase type A assigned to the human X chromosome

scientific article published on 01 February 1981

Gene therapy for brain tumors

scientific article published on 01 October 1995

Gene therapy for metastatic brain tumors by vaccination with granulocyte-macrophage colony-stimulating factor-transduced tumor cells

scientific article

Gene therapy for the nervous system: challenges and new strategies

scientific article

Gene therapy in the CNS.

scientific article

Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells

scientific article published on November 1, 1992

Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors

scientific article published in February 1994

Gene transfer into mammalian central nervous system using herpes virus vectors: extended expression of bacterial lacZ in neurons using the neuron-specific enolase promoter

scientific article published on October 1, 1992

Gene transfer into the mammalian inner ear using HSV-1 and vaccinia virus vectors

scientific article published in August 1999

Gene transfer into the nervous system

scientific article published on January 1987

Gene transfer to sensory neurons using herpes virus vectors.

scientific article published in January 1994

Gene transfer to the nigrostriatal system by hybrid herpes simplex virus/adeno-associated virus amplicon vectors

scientific article published in October 1999

Generation of stable retrovirus packaging cell lines after transduction with herpes simplex virus hybrid amplicon vectors

scientific article published on May 2002

Genetic analysis of idiopathic torsion dystonia in Ashkenazi Jews and their recent descent from a small founder population

scientific article

Genetic analysis of three patients with an 18p- syndrome and dystonia

scientific article published in February 1999

Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene

article

Genetic linkage studies in autosomal dominant parkinsonism: evaluation of seven candidate genes

scientific article published on 01 September 1994

Genetic linkage studies in autosomal dominantly inherited L-DOPA responsive parkinsonism. Evaluation of candidate genes

scientific article published on 01 January 1996

Genetic testing for early-onset torsion dystonia (DYT1): introduction of a simple screening method, experiences from testing of a large patient cohort, and ethical aspects

scientific article published in January 1999

Genetic therapy for the nervous system ⬇️

scientific article published on March 23, 2011

Genetically Engineered Microvesicles Carrying Suicide mRNA/Protein Inhibit Schwannoma Tumor Growth ⬇️

scientific article published on August 21, 2012

Genetically Modified Astrocytes Secreting Beta-Nerve Growth Factor (β-NGF) Support Adrenal Chromaffin Cells Grafted into the Striatum

scientific article published in October 1992

Genetically modified fibroblasts producing NGF protect hippocampal neurons after ischemia in the rat ⬇️

scientific article published on March 7, 1995

Genetics of primary dystonia

scientific article

Gesicles: Microvesicle "cookies" for transient information transfer between cells

scientific article published on September 2011

Glial growth factor-like activity in Schwann cell tumors

scientific article

GlioM&M: Web-based tool for studying circulating and infiltrating monocytes and macrophages in glioma

scientific article published on 18 June 2020

Glioblastoma hijacks microglial gene expression to support tumor growth

scientific article published on 16 April 2020

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

scientific article

Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21

scientific article published on 01 September 2019

Glioblastomas exploit truncated O-linked glycans for local and distant immune modulation via the macrophage galactose-type lectin

scientific article published on 04 February 2020

Glioma EVs Contribute to Immune Privilege in the Brain

scientific article published on 04 June 2019

Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression.

scientific article

Glioma-Derived miRNA-Containing Extracellular Vesicles Induce Angiogenesis by Reprogramming Brain Endothelial Cells

scientific article published on 01 February 2020

Grafting genetically modified cells into the rat brain: characteristics of E. coli beta-galactosidase as a reporter gene

scientific article published in June 1989

Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

scientific article published in December 1988

Green fluorescent protein as a reporter for retrovirus and helper virus-free HSV-1 amplicon vector-mediated gene transfer into neural cells in culture and in vivo.

scientific article published in December 1997

HSV amplicon vectors for cancer therapy

scientific article published on June 2006

HSV-1 Vectors for Gene Therapy of Experimental CNS Tumors

scientific article published on January 1, 2000

HSV-1 amplicon peptide display vector

scientific article published on January 2003

HSV-1 amplicon vector-mediated expression of ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype

scientific article

HSV-1 amplicon vectors

scientific article published on January 2002

HSV-1 amplicon vectors are a highly efficient gene delivery system for skeletal muscle myoblasts and myotubes

scientific article published in March 2000

HSV-1 amplicon vectors--simplicity and versatility

scientific article

HSV-1 virions engineered for specific binding to cell surface receptors

scientific article published on March 2004

HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part I. HSV-1 structure, replication and pathogenesis

scientific article

HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part II. Vector systems and applications

scientific article

HSV/AAV hybrid amplicon vectors extend transgene expression in human glioma cells.

scientific article published in February 1997

Haplotype analysis at the DYT1 locus in Ashkenazi Jewish patients with occupational hand dystonia

scientific article

Healing genes in the nervous system

scientific article

Helper virus-free herpes simplex virus type 1 amplicon vectors for granulocyte-macrophage colony-stimulating factor-enhanced vaccination therapy for experimental glioma

scientific article published on July 2000

Heparin affinity purification of extracellular vesicles

scientific article published on 19 May 2015

Heparin blocks transfer of extracellular vesicles between donor and recipient cells

scientific article published on 4 September 2013

Herpes simplex virus for gene delivery to neurons.

scientific article

Herpes simplex virus type 1 DNA amplified as bacterial artificial chromosome in Escherichia coli: rescue of replication-competent virus progeny and packaging of amplicon vectors

scientific article published on December 1998

Herpes simplex virus type 1 amplicon vector-mediated gene transfer to muscle

scientific article published in January 2002

Herpes simplex virus type 1 amplicons and their hybrid virus partners, EBV, AAV, and retrovirus

scientific article

Herpes simplex virus type 1-based amplicon vector systems

scientific article

Herpes simplex virus type 1/adeno-associated virus rep(+) hybrid amplicon vector improves the stability of transgene expression in human cells by site-specific integration

scientific article

Herpes simplex virus/adeno-associated virus hybrid vectors for gene transfer to neurons. Preparation and use.

scientific article

Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors.

scientific article published in February 1996

Herpesvirus-mediated gene delivery into the rat brain: specificity and efficiency of the neuron-specific enolase promoter

scientific article published on 01 October 1993

High levels of AAV vector integration into CRISPR-induced DNA breaks

scientific article published on 30 September 2019

High-affinity [3H]choline accumulation in cultured human skin fibroblasts

scientific article published on 01 February 1981

Highly polymorphic (GT)n repeat sequence in intron II of the human MAOB gene ⬇️

scientific article published on 01 January 1992

Human monoamine oxidase A gene determines levels of enzyme activity ⬇️

scientific article published on August 1, 1991

Human skin fibroblasts in neuropsychiatric disorders.

scientific article published in January 1980

Hybrid vector designs to control the delivery, fate and expression of transgenes

scientific article

Hybrid vectors: a new generation of virus-based vectors designed to control the cellular fate of delivered genes ⬇️

scientific article published on December 1, 1997

Identification of a highly polymorphic microsatellite VNTR within the argininosuccinate synthetase locus: exclusion of the dystonia gene on 9q32-34 as the cause of dopa-responsive dystonia in a large kindred

scientific article

Identification of a novel gene (HSN2) causing hereditary sensory and autonomic neuropathy type II through the Study of Canadian Genetic Isolates

scientific article

Imaging and therapy of experimental schwannomas using HSV amplicon vector-encoding apoptotic protein under Schwann cell promoter

scientific article published on 16 October 2009

Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours

scientific article published on 21 March 2019

Imaging gene delivery in a mouse model of congenital neuronal ceroid lipofuscinosis ⬇️

scientific article published on September 8, 2011

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles.

scientific article

Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons

scientific article

Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation.

scientific article published on June 2005

Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat.

scientific article

Improved HSV-1 amplicon packaging system using ICP27-deleted, oversized HSV-1 BAC DNA.

scientific article published on January 2003

Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome

scientific article published in April 2001

Improvement in reproductive parameters in hypogonadal female mice by regulated gene replacement therapy in the central nervous system

scientific article published on 3 May 2007

In vitro translation of proteins with terminal deletions by SP6 RNA polymerase-mediated transcription of PCR products ⬇️

scientific article published on 01 November 1992

In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas

scientific article

In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis.

scientific article published in June 2005

In vivo tomographic imaging of red-shifted fluorescent proteins

scientific article

In vivo tracking of neural progenitor cell migration to glioblastomas

scientific article

Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy

scientific article published in May 2004

Inherited levels of A and B types of monoamine oxidase activity

scientific article

Inhibition of N-linked glycosylation prevents inclusion formation by the dystonia-related mutant form of torsinA.

scientific article

Integration of active human beta-galactosidase gene (100 kb) into genome using HSV/AAV amplicon vector

scientific article published on 26 April 2007

Intra-arterial virus and nonvirus vector-mediated gene transfer to experimental rat brain tumors

scientific article published in January 1999

Intraarterial delivery of adenovirus vectors and liposome-DNA complexes to experimental brain neoplasms

scientific article published in January 1999

Intracerebral implantation of nerve growth factor-producing fibroblasts protects striatum against neurotoxic levels of excitatory amino acids ⬇️

scientific article published on January 1, 1991

Intrafamilial phenotypic variability of the DYT1 dystonia: from asymptomatic TOR1A gene carrier status to dystonic storm

scientific article published on 01 March 2002

Intravascular delivery of neural stem cell lines to target intracranial and extracranial tumors of neural and non-neural origin.

scientific article

Introduction of a foreign gene (Escherichia coli lacZ) into rat neostriatal neurons using herpes simplex virus mutants: A light and electron microscopic study ⬇️

scientific article published on March 1, 1992

Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake

scientific article published on 6 April 2016

Isolation and characterization of a candidate gene for Norrie disease

scientific article published in June 1992

Isolation of the mRNA encoding rat liver catechol-O-methyltransferase

scientific article published on 01 February 1989

Isolation, characterization, and recovery of small peptide phage display epitopes selected against viable malignant glioma cells.

scientific article

Large and small extracellular vesicles released by glioma cells in vitro and in vivo

scientific article published on 27 November 2019

Linkage analysis in a family with dominantly inherited torsion dystonia: exclusion of the pro-opiomelanocortin and glutamic acid decarboxylase genes and other chromosomal regions using DNA polymorphisms

scientific article published on 01 May 1986

Linkage analysis in juvenile neuronal ceroid lipofuscinosis

scientific article published on February 1992

Linkage disequilibrium between the juvenile neuronal ceroid lipofuscinosis gene and marker loci on chromosome 16p 12.1.

scientific article published on January 1994

Live visualization of herpes simplex virus type 1 compartment dynamics

scientific article published on 12 March 2008

Local protective effects of nerve growth factor-secreting fibroblasts against excitotoxic lesions in the rat striatum

scientific article published on February 1993

Localization of human monoamine oxidase-A gene to Xp11.23-11.4 by in situ hybridization: Implications for norrie disease

article

Localization of juvenile, but not late-infantile, neuronal ceroid lipofuscinosis on chromosome 16

scientific article

Localization of the gene for familial dysautonomia on chromosome 9 and definition of DNA markers for genetic diagnosis

scientific article published in June 1993

Long-Term Therapeutic Efficacy of Intravenous AAV-Mediated Hamartin Replacement in Mouse Model of Tuberous Sclerosis Type 1

scientific article published on 16 August 2019

Long-term expression of the gene encoding green fluorescent protein in murine hematopoietic cells using retroviral gene transfer ⬇️

scientific article published on May 15, 1998

Long-term survival in a rodent brain tumor model by bradykinin-enhanced intra-arterial delivery of a therapeutic herpes simplex virus vector

scientific article published on May 1, 1998

Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment.

scientific article published in October 1996

Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene.

scientific article

Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery

scientific article published on December 2005

Mapping theIn VivoDistribution of Herpes Simplex Virions ⬇️

scientific article published on July 20, 1998

Marked amine and amine metabolite changes in Norrie disease patients with an X-chromosomal deletion affecting monoamine oxidase

scientific article published in January 1990

Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium

scientific article

Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles

scientific article published on 22 November 2019

Metabolic biotinylation of cell surface receptors for in vivo imaging

scientific article published in May 2006

Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles

MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development

scientific article

Microfluidic isolation and transcriptome analysis of serum microvesicles

scientific article

Microfluidic platform to evaluate migration of cells from patients with DYT1 dystonia

scientific article published on 29 May 2014

Microvesicle-associated AAV vector as a novel gene delivery system

scientific article published on 7 February 2012

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Models for inherited susceptibility to cancer in the nervous system: a molecular-genetic approach to neurofibromatosis

scientific article published on January 1987

Modified herpes simplex virus delivery of enhanced GFP into the central nervous system.

scientific article published in December 2002

Molecular cloning and expression of rat torsinA in the normal and genetically dystonic (dt) rat.

scientific article published in May 2002

Molecular genetic approaches to neurologic and psychiatric diseases

scientific article

Molecular genetic insights into neurologic diseases

scientific article published in January 1987

Molecular genetics of an autosomal dominant form of torsion dystonia

scientific article published on 01 January 1988

Molecular genetics of the monoamine oxidases

scientific article published on July 1989

Molecular imaging of gene therapy for cancer

scientific article published on August 2004

Molecular pathways in dystonia ⬇️

scientific article published on 04 December 2010

Monoamine Oxidase Activity Decreased in Cells Lacking Hypoxanthine Phosphoribosyltransferase Activity ⬇️

scientific article published on 01 June 1976

Monoamine oxidase (MAO) activity as a determinant in human neurophysiology ⬇️

scientific article published on February 1, 1982

Monoamine oxidase A and B in cultured cells ⬇️

scientific article published on June 1, 1978

Monoamine oxidase and catechol-O-methyltransferase activities in cultured fibroblasts and blood cells from children with autism and the Gilles de la Tourette syndrome

scientific article published in May 1980

Monoamine oxidase and catechol-O-methyltransferase activities in cultured human skin fibroblasts

scientific article published on 01 December 1976

Monoamine oxidase type a in fibroblasts from patients with bipolar depressive illness

scientific article published on 01 July 1980

Monoamine oxidases A and B are differentially regulated by glucocorticoids and "aging" in human skin fibroblasts

scientific article

MspI RFLP for human MAOA gene

scientific article published on December 1989

Multidimensional communication in the microenvirons of glioblastoma

scientific article published on 01 August 2018

Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies

scientific article published in August 1999

Multiplexed Profiling of Single Extracellular Vesicles.

scientific article published on 29 December 2017

Mutant Allele-Specific CRISPR Disruption in DYT1 Dystonia Fibroblasts Restores Cell Function

scientific article published on 15 May 2020

Mutant human torsinA, responsible for early-onset dystonia, dominantly suppresses GTPCH expression, dopamine levels and locomotion in Drosophila melanogaster

scientific article

Mutant sodium channel for tumor therapy.

scientific article

Mutant torsinA in the heterozygous DYT1 state compromises HSV propagation in infected neurons and fibroblasts

scientific article published on 2 February 2018

Mutant torsinA interferes with protein processing through the secretory pathway in DYT1 dystonia cells

scholarly article

Mutant torsinA, responsible for early-onset torsion dystonia, forms membrane inclusions in cultured neural cells

scientific journal article

Mutational analysis of the human MAOA gene

scientific article published on 01 February 1996

Mutations in DYT1: extension of the phenotypic and mutational spectrum

scientific article published in February 2004

Mutations in the Norrie disease gene

scientific article

Nerve growth factor released by transgenic astrocytes enhances the function of adrenal chromaffin cell grafts in a rat model of Parkinson's disease

scientific article published on 01 September 1994

Neural precursor cells and their role in neuro-oncology

scientific article

Neural precursor cells for delivery of replication-conditional HSV-1 vectors to intracerebral gliomas

scientific article published in April 2000

Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas

scientific article published in November 2000

Neurotransmitter metabolism in cell culture ⬇️

scientific article published on November 1, 1976

Neurotransmitter metabolism in murine neuroblastoma cells ⬇️

scientific article published on February 1, 1976

New Prodrug Activation Gene Therapy for Cancer Using Cytochrome P450 4B1 and 2-Aminoanthracene/4-Ipomeanol ⬇️

scientific article published on June 10, 1998

New Technologies for Analysis of Extracellular Vesicles

scientific article published on 31 January 2018

New methods for investigation of neuronal migration in embryonic brain explants

scientific article

Noninvasive in vivo monitoring of extracellular vesicles

scientific article published in January 2014

Norrie disease and MAO genes: nearest neighbors

scientific article published on January 1995

Norrie disease gene: characterization of deletions and possible function

scientific article

Novel mutation in the TOR1A (DYT1) gene in atypical early onset dystonia and polymorphisms in dystonia and early onset parkinsonism.

scientific article

Organization of the human monoamine oxidase genes and long-range physical mapping around them

scientific article

P06.07 Immune evasion mediated by PD-L1 on glioblastoma derived extracellular vesicles.

scientific article

Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: expanding the phenotype

scientific article published in July 2000

Perinuclear biogenesis of mutant torsin-A inclusions in cultured cells infected with tetracycline-regulated herpes simplex virus type 1 amplicon vectors

scientific article published on January 2004

Peripherin gene is linked to keratin 18 gene on human chromosome 12

scientific article published on 01 January 1995

Phenotypic variability in a large kindred (Family LA) with deletions in the parkin gene

scientific article published on 01 March 2002

Phenylalanine hydroxylase in melanoma cells ⬇️

scientific article published on March 1, 1978

Physical fine-mapping of a deletion spanning the Norrie gene

scientific article published on December 1989

Plasma amine oxidase activities in Norrie disease patients with an X-chromosomal deletion affecting monoamine oxidase

scientific article published on 01 January 1991

Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo.

scientific article published in April 2001

Potential Transfer of Polyglutamine and CAG-Repeat RNA in Extracellular Vesicles in Huntington's Disease: Background and Evaluation in Cell Culture

scientific article published on 07 March 2016

Potential of gene therapy for brain tumors

scientific article

Potentiated gene delivery to tumors using herpes simplex virus/Epstein-Barr virus/RV tribrid amplicon vectors

scientific article published on May 2003

Pre-existing herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector ⬇️

scientific article published on June 1, 1998

Precise genetic mapping and haplotype analysis of the familial dysautonomia gene on human chromosome 9q31

scientific article

Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma

scientific article published on 24 July 2017

Presence of free cyclic AMP receptor protein and regulation of its level by cyclic AMP in neuroblastoma-glioma hybrid cells ⬇️

scientific article published on July 1, 1979

Preventing growth of brain tumors by creating a zone of resistance

scientific article

Prodrug activation enzymes in cancer gene therapy

scientific article

Properties of monoamine oxidase in control and Lesch-Nyhan fibroblasts

scientific article published on 01 June 1980

Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

scientific article

Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy

scientific article

Quantitation of HSV mass distribution in a rodent brain tumor model.

scientific article published in October 2000

RESPONSE: Re: Folylpolyglutamyl Synthetase Gene Transfer and Glioma Antifolate Sensitivity in Culture and In Vivo

scientific article published on 01 December 1999

RFLP for human DBH (dopamine beta-hydroxylase)

scientific article published on January 1990

RNA delivery by extracellular vesicles in mammalian cells and its applications

scientific article published on 26 May 2020

RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls

scientific article

RNAi blocks DYT1 mutant torsinA inclusions in neurons

scientific article

Rapid-onset dystonia-parkinsonism

scientific article published on 01 December 1993

Rapid-onset dystonia-parkinsonism: a report of clinical, biochemical, and genetic studies in two families

scientific article published on 01 January 1998

Rapid-onset dystonia-parkinsonism: linkage to chromosome 19q13

scientific article (publication date: August 1999)

Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo

scientific article published in October 2003

Receptor binding activities of biotinylated derivatives of beta-nerve growth factor

scientific article published on 01 February 1986

Refined linkage to the RDP/DYT12 locus on 19q13.2 and evaluation of GRIK5 as a candidate gene

scientific article

Refocus the Recombinant DNA Advisory Committee ⬇️

scientific article published on 06 July 2012

Regression of schwannomas induced by adeno-associated virus-mediated delivery of caspase-1.

scientific article published on 30 January 2013

Regulated expression of the diphtheria toxin A gene in human glioma cells using prokaryotic transcriptional control elements

scientific article published on July 1997

Regulation of synthesis of guanosine 3′:5′-cyclic monophosphate in neuroblastoma cells ⬇️

scientific article published on October 15, 1978

Relationship between platelet monoamine oxidase B activity and alleles at the MAOB locus

scientific article published on 01 December 1992

Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV.

scientific article published on 9 January 2017

Reserpine sensitivity of catecholamine metabolism in murine neuroblastoma clone N1E-115 ⬇️

scientific article published on 01 December 1975

Retinal ganglion cell survival is promoted by genetically modified astrocytes designed to secrete brain-derived neurotrophic factor (BDNF).

scientific article published in May 1994

Retrograde axonal transport of herpes simplex virus: evidence for a single mechanism and a role for tegument

scientific article

Retroviral delivery and tetracycline-dependent expression of IL-1beta-converting enzyme (ICE) in a rat glioma model provides controlled induction of apoptotic death in tumor cells.

scientific article published in December 1996

Retrovirus-mediated gene therapy of experimental brain neoplasms using the herpes simplex virus-thymidine kinase/ganciclovir paradigm

scientific article published on March 1996

Retrovirus-mediated gene transfer of beta-nerve growth factor into mouse pituitary line AtT-20.

scientific article published in February 1988

Role of parkin mutations in 111 community-based patients with early-onset parkinsonism

scientific article published on 01 May 2002

SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions

scientific article

Screen for MAOA mutations in target human groups

scientific article published on February 1999

Search for a founder mutation in idiopathic focal dystonia from Northern Germany

scientific article

Search for the PARK3 founder haplotype in a large cohort of patients with Parkinson's disease from northern Germany

scientific article published on 01 July 1999

Secondary dystonia and the DYTI gene

scientific article published on 01 June 1997

Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells

scientific article published on 04 October 2018

Selection for neuroblastoma cells that synthesize certain transmitters

scientific article published on June 1974

Selective delivery of herpes virus vectors to experimental brain tumors using RMP-7.

scientific article published in January 1999

Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene

scientific article published on June 1991

Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms.

scientific article published in December 1995

Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells

scientific article published on January 1996

Single HSV-amplicon vector mediates drug-induced gene expression via dimerizer system.

scientific article published on June 2003

Single-step conversion of cells to retrovirus vector producers with herpes simplex virus-Epstein-Barr virus hybrid amplicons

scientific article

Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation

scientific article published on 01 April 2019

Soluble and particulate forms of rat catechol-O-methyltransferase distinguished by gel electrophoresis and immune fixation

scientific article published in February 1985

Specificity of antisera prepared against pure bovine MAO-B.

scientific article published in October 1983

Squid axoplasm supports the retrograde axonal transport of herpes simplex virus

scientific article

Stochastic model of Tsc1 lesions in mouse brain

scientific article

Striatal degeneration induced by mitochondrial blockade is prevented by biologically delivered NGF.

scientific article published on July 1993

Structural Features of Human Monoamine Oxidase A Elucidated from cDNA and Peptide Sequences ⬇️

scientific article published on 01 October 1988

Structural gene for beta-nerve growth factor not defective in familial dysautonomia ⬇️

scientific article published on July 1, 1984

Structure of the human gene for monoamine oxidase type A.

scientific article

Survival and differentiation within the adult mouse striatum of grafted rat pheochromocytoma cells (PC12) genetically modified to express recombinant beta-NGF.

scientific article published on May 1991

Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model.

scientific article published on 24 May 2015

Synergistic Anticancer Effects of Ganciclovir/Thymidine Kinase and 5-Fluorocytosine/Cytosine Deaminase Gene Therapies ⬇️

scientific article published on March 4, 1998

TAF1 Transcripts and Neurofilament Light Chain as Biomarkers for X-Linked Dystonia-Parkinsonism

scientific article published on 25 September 2020

TMIC-28. GLIOBLASTOMA EXPLOITS CELL SURFACE GLYCOSYLATION-MEDIATED IMMUNE REGULATORY CIRCUITS FOR IMMUNE ESCAPE

scientific article published on 5 November 2018

Tannous et al. Respond

scientific article published on August 2009

Targeted integration of functional human ATM cDNA into genome mediated by HSV/AAV hybrid amplicon vector

scientific article published on 13 November 2007

Targeted transgene integration into transgenic mouse fibroblasts carrying the full-length human AAVS1 locus mediated by HSV/AAV rep(+) hybrid amplicon vector.

scientific article published in September 2003

Targeting HSV amplicon vectors

scientific article published on June 2004

Targeting HSV-1 virions for specific binding to epidermal growth factor receptor-vIII-bearing tumor cells

scientific article

Targeting gene therapy vectors to CNS malignancies.

scientific article

Targeting of liposomes to cells bearing nerve growth factor receptors mediated by biotinylated nerve growth factor

scientific article published on 01 March 1987

Targeting transforming growth factor alpha expression to discrete loci of the neuroendocrine brain induces female sexual precocity

scientific article

Temperature-Sensitive Divisionless Mutant of Bacillus subtilis Defective in the Initiation of Septation ⬇️

scientific article published on February 1, 1973

The ASGCT in 2012: Charting a Path to Bring Novel Biologic Therapies to the Clinic

scientific article published in July 2012

The DYT1 phenotype and guidelines for diagnostic testing

scientific article

The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research

scientific article published on 01 April 2019

The GAG deletion of the DYT1 gene is infrequent in musicians with focal dystonia

scientific article

The Norrie disease gene maps to a 150 kb region on chromosome Xp11.3.

scientific article

The TOR1A (DYT1) gene family and its role in early onset torsion dystonia

scientific article

The autosomal dominant dystonias

scientific article published on October 1, 1992

The catechol estrogen, 2-hydroxyestradiol, inhibits catechol-O-methyltransferase activity in neuroblastoma cells

scientific article published on 01 July 1978

The early onset dystonia protein torsinA interacts with kinesin light chain 1

scientific article

The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein ⬇️

scientific article published on September 1, 1997

The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response

scientific article

The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response

The gelsolin (GSN) cDNA clone, from 9q32-34, identifies BclI and StuI RFLPs

scientific article published on June 1989

The gene (DYT1) for early-onset torsion dystonia encodes a novel protein related to the Clp protease/heat shock family

scientific article published on January 1, 1998

The human gene for neurotrophic tyrosine kinase receptor type 2 (NTRK2) is located on chromosome 9 but is not the familial dysautonomia gene

scientific article

The importance of gene dosage studies: mutational analysis of the parkin gene in early-onset parkinsonism

scientific article published on 01 August 2001

The launch of Journal of Extracellular Vesicles (JEV), the official journal of the International Society for Extracellular Vesicles - about microvesicles, exosomes, ectosomes and other extracellular vesicles

scientific article published on 16 April 2012

The neurobiology of Down syndrome

The pathophysiological basis of dystonias.

scientific article published on March 2008

The primary structure of bovine monoamine oxidase type A. Comparison with peptide sequences of bovine monoamine oxidase type B and other flavoenzymes ⬇️

scientific article published on April 1989

The role of the DYT1 gene in secondary dystonia

scientific article published on January 1, 1998

The role of ‘tumor suppressor’ genes in neural tumors ⬇️

scientific article published on January 1, 1990

Therapeutic applications of extracellular vesicles: clinical promise and open questions

scientific article published on 3 October 2014

Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy.

scientific article published in November 1997

TorsinA and early-onset torsion dystonia

scientific article published on January 1, 2004

TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation

scientific article published on November 2002

TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton

scientific article

TorsinA expression is detectable in human infants as young as 4 weeks old.

scientific article published on 9 April 2005

TorsinA in PC12 cells: localization in the endoplasmic reticulum and response to stress

scientific article

TorsinA in the nuclear envelope

scholarly article

TorsinA participates in endoplasmic reticulum-associated degradation

scientific article

TorsinA protein and neuropathology in early onset generalized dystonia with GAG deletion

scientific article published in February 2003

TorsinA: movement at many levels

scientific article

TorsinB expression in the developing human brain

scientific article

TorsinB--perinuclear location and association with torsinA

scientific article

Torsion dystonia genes in two populations confined to a small region on chromosome 9q32-34.

scientific article published on August 1991

Transcription factors in inner ear development

scientific article

Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants

scientific article published on August 1990

Transgene inheritance and retroviral infection contribute to the efficiency of gene expression in solid tumors inoculated with retroviral vector producer cells

scientific article

Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases

scientific article published in February 2013

Transplantation of a polymer-encapsulated cell line genetically engineered to release NGF.

scientific article

Transport of tyrosine, phenylalanine, tryptophan and glycine in neuroblastoma clones

scientific article published on 01 January 1977

Treatment of Schwannomas with an Oncolytic Recombinant Herpes Simplex Virus in Murine Models of Neurofibromatosis Type 2

Treatment of implantable NF2 schwannoma tumor models with oncolytic herpes simplex virus G47Delta.

scientific article published on 16 February 2007

Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2.

scientific article

Tumor cell endocytosis imaging facilitates delineation of the glioma-brain interface.

scientific article published on January 1997

Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

scientific article

Tyrosine-dependent increase of tyrosine hydroxylase in neuroblastoma cells

scientific article published on 01 December 1974

Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunction

scientific article

Update from the 2013 International Neurofibromatosis Conference

scientific article published on 24 September 2014

Update on herpesvirus amplicon vectors

scientific article published in October 2004

Uptake and binding of dopamine and 6-hydroxydopamine in murine neuroblastoma and fibroblast cells

scientific article published on February 15, 1976

Vaccination for experimental gliomas using GM-CSF-transduced glioma cells

scientific article published on November 1, 1997

Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation

scientific article

Viral vectors for gene delivery to the nervous system ⬇️

scientific article published on May 1, 2003

Viral vectors for therapy of neurologic diseases

scientific article published on 20 February 2016

Virus vectors for gene delivery to the nervous system

scientific article published in January 1995

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

scientific article

Voltage-sensitive calcium channels regulate guanosine 3',5'-cyclic monophosphate levels in neuroblastoma cells ⬇️

scientific article published on December 1, 1978

[18F]-Dopa positron emission tomography imaging in early-stage, non-parkin juvenile parkinsonism

scientific article

[Genetics of dystonia]

scientific article published on 01 June 2000

beta-Galactosidase gene mutations in patients with slowly progressive GM1 gangliosidosis

scientific article (publication date: June 1997)

dtorsin, the Drosophila Ortholog of the Early-Onset Dystonia TOR1A (DYT1), Plays a Novel Role in Dopamine Metabolism ⬇️

scientific article published on October 12, 2011

miR-1289 and "Zipcode"-like Sequence Enrich mRNAs in Microvesicles

scientific article

miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells

scientific article

miRNA signature of schwannomas: possible role(s) of "tumor suppressor" miRNAs in benign tumors

scientific article

miRNA-7 Attenuation in Schwannoma Tumors Stimulates Growth by Upregulating Three Oncogenic Signaling Pathways ⬇️

scientific article published on December 13, 2010

siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells

scientific article published on 7 February 2008

α-Synuclein in Extracellular Vesicles: Functional Implications and Diagnostic Opportunities

scientific article published on 18 March 2016

Paulina is supported by:

About Paulina

Help