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List of works by Julien Ablain

8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation

scientific article published on 4 February 2013

A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish

scientific article

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation

scientific article published on 28 January 2016

Activation of a promyelocytic leukemia-tumor protein 53 axis underlies acute promyelocytic leukemia cure

scientific article published on 12 January 2014

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

scientific article

Clearance of PML/RARA-bound promoters suffice to initiate APL differentiation

scientific article published on 25 September 2014

Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC

scientific article

Context-selective death of acute myeloid leukemia cells triggered by the novel hybrid retinoid-HDAC inhibitor MC2392.

scientific article published on 24 February 2014

FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity

scientific article published in Journal of Biological Chemistry

How animal models of leukaemias have already benefited patients

scientific article

Human tumor genomics and zebrafish modeling identify loss as a driver of mucosal melanoma

scientific article published in Science

Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma

scientific article published on 01 June 2020

Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion

scientific article published on 05 June 2018

Of fish and men: using zebrafish to fight human diseases.

scientific article published in December 2013

Retinoic acid signaling in cancer: The parable of acute promyelocytic leukemia

scientific article

Revisiting the differentiation paradigm in acute promyelocytic leukemia

scientific article published on 28 March 2011

SPRED1 deletion confers resistance to MAPK inhibition in melanoma

scientific article published on 01 March 2021

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

scientific article published on April 2016

The Drug-Induced Degradation of Oncoproteins: An Unexpected Achilles' Heel of Cancer Cells? ⬇️

scientific article published on July 1, 2011

Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia ⬇️

scientific article

Uncoupling RARA transcriptional activation and degradation clarifies the bases for APL response to therapies

scientific article published on 18 March 2013

Zebrafish patient avatars in cancer biology and precision cancer therapy

scientific article published on 06 April 2020

p53 as an Effector or Inhibitor of Therapy Response

scientific article

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