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List of works by Giovanni Grignani

A phase 2 trial of imatinib mesylate in patients with recurrent nonresectable chondrosarcomas expressing platelet-derived growth factor receptor-α or -β: An Italian Sarcoma Group study.

scientific article

A phase II randomised (calibrated design) study on the activity of the single-agent trabectedin in metastatic or locally relapsed uterine leiomyosarcoma.

scientific article published on 30 July 2018

A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study

scientific article published on April 28, 2011

Activity of Eribulin in Patients With Advanced Liposarcoma Demonstrated in a Subgroup Analysis From a Randomized Phase III Study of Eribulin Versus Dacarbazine.

scientific article

Activity of cytokine-induced killer cells against bone and soft tissue sarcoma

scientific article published on 17 March 2014

Adoptive immunotherapy against sarcomas.

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Alpha-fetoprotein elevation in NUT midline carcinoma: a case report

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An acute hepatitis resembling autoimmune hepatitis occurring during imatinib therapy in a gastrointestinal stromal tumor patient.

scientific article published in December 2009

Analytic and Dynamic Secretory Profile of Patient-Derived Cytokine-Induced Killer Cells.

scientific article published on 9 August 2017

Anthracycline, Gemcitabine, and Pazopanib in Epithelioid Sarcoma: A Multi-institutional Case Series

scientific article published on 13 September 2018

Anticoagulation for central venous catheters in patients with cancer

scientific article published in October 2014

CD44v6 as innovative sarcoma target for CAR-redirected CIK cells.

scientific article published on 15 February 2018

Cabozantinib Affects Osteosarcoma Growth Through A Direct Effect On Tumor Cells and Modifications In Bone Microenvironment.

scientific article published on 8 March 2018

Complete remission of paraneoplastic vanishing bile duct syndrome after the successful treatment of Hodgkin's lymphoma: a case report and review of the literature.

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Complete resolution of life-threatening bleomycin-induced pneumonitis after treatment with imatinib mesylate in a patient with Hodgkin's lymphoma: hope for severe chemotherapy-induced toxicity?

scientific article published on 27 June 2011

Confirmed Activity and Tolerability of Weekly Paclitaxel in the Treatment of Advanced Angiosarcoma

scientific article published on 25 February 2016

Cytokine Induced Killer cells are effective against sarcoma cancer stem cells spared by chemotherapy and target therapy

scientific article published on 06 August 2018

Cytokine-Induced Killer Cells Kill Chemo-surviving Melanoma Cancer Stem Cells.

scientific article published on 4 November 2016

Cytokine-induced killer cells eradicate bone and soft-tissue sarcomas.

scientific article published on 19 December 2013

Defining the role of neoadjuvant systemic therapy in high-risk retroperitoneal sarcoma: A multi - institutional study from the Transatlantic Australasian Retroperitoneal Sarcoma Working Group

scientific article published on 18 November 2020

Delving into PARP inhibition from bench to bedside and back

scientific article published on 19 November 2019

Doxorubicin plus dacarbazine, doxorubicin plus ifosfamide, or doxorubicin alone as a first-line treatment for advanced leiomyosarcoma: A propensity score matching analysis from the European Organization for Research and Treatment of Cancer Soft Tiss

scientific article published on 04 March 2020

EURO-B.O.S.S.: A European study on chemotherapy in bone-sarcoma patients aged over 40: Outcome in primary high-grade osteosarcoma.

scientific article

Effective activity of cytokine-induced killer cells against autologous metastatic melanoma including cells with stemness features.

scientific article published on 21 June 2013

Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial.

scientific article published on 10 February 2016

Ex vivo allogeneic stimulation significantly improves expansion of cytokine-induced killer cells without increasing their alloreactivity across HLA barriers

scientific article published on 01 September 2012

Extraskeletal osteosarcoma: A European Musculoskeletal Oncology Society study on 266 patients.

scientific article

Front-line window therapy with cisplatin in patients with primary disseminated Ewing sarcoma: A study by the Associazione Italiana di Ematologia ed Oncologia Pediatrica and Italian Sarcoma Group.

scientific article published on 14 June 2017

Gain of FGF4 is a frequent event in KIT/PDGFRA/SDH/RAS-P WT GIST

scientific article published on 16 April 2019

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published in October 2018

Gemcitabine and docetaxel in relapsed and unresectable high-grade osteosarcoma and spindle cell sarcoma of bone

scientific article

Genome-Wide Analysis Identifies MEN1 and MAX Mutations and a Neuroendocrine-Like Molecular Heterogeneity in Quadruple WT GIST.

scientific article published on 27 January 2017

Gingival metastasis of a radiotherapy-induced breast angiosarcoma: diagnosis and multidisciplinary treatment achieving a prolonged complete remission

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High Dose Ifosfamide in Relapsed and Unresectable High-Grade Osteosarcoma Patients: A Retrospective Series

scientific article published on 31 October 2020

High-risk soft tissue sarcomas treated with perioperative chemotherapy: Improving prognostic classification in a randomised clinical trial

scientific article published on 21 February 2018

Imatinib rechallenge in patients with advanced gastrointestinal stromal tumors following progression with imatinib, sunitinib and regorafenib

scientific article published on 29 August 2018

Impact of a risk-based follow-up in patients affected by gastrointestinal stromal tumour.

scientific article published on 24 April 2017

Irinotecan and temozolomide in recurrent Ewing sarcoma: an analysis in 51 adult and pediatric patients.

scientific article published on 13 March 2018

Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity

scientific article published on 5 May 2016

MOPP/EBV/CAD hybrid chemotherapy with or without limited radiotherapy in advanced or unfavorably presenting Hodgkin's disease: a report from the Italian Lymphoma Study Group

scientific article published on 01 April 1993

Next generation immune-checkpoints for cancer therapy.

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Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial

scientific article published on 01 November 2020

Olaratumab: PDGFR-α inhibition as a novel tool in the treatment of advanced soft tissue sarcomas

scientific article published on 15 July 2017

PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models

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Painful pathologic fracture of the humerus: percutaneous osteoplasty with bone marrow nails under hybrid computed tomography and fluoroscopic guidance.

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Pancreaticoduodenectomy in the surgical management of primary retroperitoneal sarcoma.

scientific article published on 5 February 2018

Patterns of recurrence and survival probability after second recurrence of retroperitoneal sarcoma: A study from TARPSWG

scientific article published on 14 August 2020

Pazopanib for treatment of advanced extraskeletal myxoid chondrosarcoma: a multicentre, single-arm, phase 2 trial

scientific article published on 19 July 2019

Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial

scientific article published on 18 December 2018

Pazopanib in advanced vascular sarcomas: an EORTC Soft Tissue and Bone Sarcoma Group (STBSG) retrospective analysis

scientific article published on 14 November 2016

Pharmacokinetics, safety, and activity of trabectedin as first-line treatment in elderly patients who are affected by advanced sarcoma and are unfit to receive standard chemotherapy: A phase 2 study (TR1US Study) from the Italian Sarcoma Group

scientific article published on 04 August 2020

Post-Transplant Cyclophosphamide and Tacrolimus-Mycophenolate Mofetil Combination Prevents Graft-versus-Host Disease in Allogeneic Peripheral Blood Hematopoietic Cell Transplantation from HLA-Matched Donors.

scientific article

Preclinical and clinical evidence of activity of pazopanib in solitary fibrous tumour

scientific article published on 27 September 2014

Predicting Survival in Patients Undergoing Resection for Locally Recurrent Retroperitoneal Sarcoma: A Study and Novel Nomogram from TARPSWG

scientific article published on 05 February 2019

Preoperative chemo-radiation therapy for localised retroperitoneal sarcoma: a phase I-II study from the Italian Sarcoma Group.

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Primary metastatic Ewing's family tumors: results of the Italian Sarcoma Group and Scandinavian Sarcoma Group ISG/SSG IV Study including myeloablative chemotherapy and total-lung irradiation

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Progressive necrotic myelopathy as a paraneoplastic syndrome: report of a case and some pathogenetic considerations

scientific article published on January 1, 1992

Prolonged disease stability with trabectedin in a heavily pretreated elderly patient with metastatic leiomyosarcoma of the thigh and renal failure: a case report and review of the literature.

scientific article published on January 2013

Quality of surgery and neoadjuvant combined therapy in the ISG-GEIS trial on soft tissue sarcomas of limbs and trunk wall.

scientific article published on 30 October 2012

Response to eribulin in a patient with metastatic uterine leiomyosarcoma: a case report

scientific article published on 09 January 2020

Short, full-dose adjuvant chemotherapy (CT) in high-risk adult soft tissue sarcomas (STS): long-term follow-up of a randomized clinical trial from the Italian Sarcoma Group and the Spanish Sarcoma Group

scientific article published on 11 October 2016

Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Soft tissue sarcoma in Italy: From epidemiological data to clinical networking to improve patient care and outcomes

scientific article published on 11 March 2019

Sorafenib and everolimus for patients with unresectable high-grade osteosarcoma progressing after standard treatment: a non-randomised phase 2 clinical trial.

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Sporadic desmoid-type fibromatosis: a stepwise approach to a non-metastasising neoplasm--a position paper from the Italian and the French Sarcoma Group

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Successful treatment of gemcitabine-induced acute interstitial pneumonia with imatinib mesylate: a case report

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Telomere loss in Philadelphia-negative hematopoiesis after successful treatment of chronic myeloid leukemia: evidence for premature aging of the myeloid compartment.

scientific article published on 9 June 2012

The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 upregulation in osteosarcoma preclinical models.

scientific article published on 22 February 2013

The combination of sorafenib and everolimus shows antitumor activity in preclinical models of malignant pleural mesothelioma

scientific article published on 8 May 2015

Trabectedin and olaparib in patients with advanced and non-resectable bone and soft-tissue sarcomas (TOMAS): an open-label, phase 1b study from the Italian Sarcoma Group

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Trabectedin clinical cases: use according to indication in diverse clinical scenarios

scientific article published on January 2015

Treatment patterns and clinical outcomes with pazopanib in patients with advanced soft tissue sarcomas in a compassionate use setting: results of the SPIRE study().

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Tumor response assessment by modified Choi criteria in localized high-risk soft tissue sarcoma treated with chemotherapy

scientific article published on 17 May 2012