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List of works by Christoph Arenz

A Fast and Easy Method for Specific Detection of Circular RNA by Rolling-Circle Amplification

scientific article published on 27 November 2019

A Rapid Assay for miRNA Maturation by Using Unmodified pre‐miRNA

scientific article published on August 18, 2011

A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones

scientific article published on 01 May 2010

A chemo-enzymatic approach to specifically click-modified RNA.

scientific article published on 11 March 2013

A photocaged inhibitor of acid sphingomyelinase

scientific article published on 12 November 2020

A series of ceramide analogs modified at the 1-position with potent activity against the intracellular growth of Chlamydia trachomatis

scientific article published on 23 October 2015

Amplification of a FRET Probe by Lipid-Water Partition for the Detection of Acid Sphingomyelinase in Live Cells.

scientific article published on 3 February 2017

Assaying Dicer-mediated miRNA maturation by means of fluorescent substrates.

scientific article published in January 2014

CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction

scientific article

DNA made of purines only.

scientific article published in May 2007

Detection of microRNA maturation using unmodified pre-microRNA and branched rolling circle amplification.

scientific article published in January 2014

Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein

article

Development of carbohydrate-derived inhibitors of acid sphingomyelinase.

scientific article

Differences and Similarities in TRAIL- and Tumor Necrosis Factor-Mediated Necroptotic Signaling in Cancer Cells

scientific article published on 15 August 2016

Differential-Mobility Spectrometry of 1-Deoxysphingosine Isomers: New Insights into the Gas Phase Structures of Ionized Lipids.

scientific article published on 2 April 2018

Elemental labelling and mass spectrometry for the specific detection of sulfenic acid groups in model peptides: a proof of concept

scientific article published on 17 January 2017

FRET probes for measuring sphingolipid metabolizing enzyme activity

scholarly article by Zainelabdeen H Mohamed published in September 2018

Facile synthesis of the CERT inhibitor HPA-12 and some novel derivatives

scientific article published on 2 June 2014

Heat shock protein-based therapy as a potential candidate for treating the sphingolipidoses.

scientific article

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

scientific article

Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening

scientific article published on 31 July 2020

Improved plaque assay identifies a novel anti-Chlamydia ceramide derivative with altered intracellular localization

scientific article

Inhibitors of Ceramidases

scientific article published on 25 July 2015

Labeled chemical biology tools for investigating sphingolipid metabolism, trafficking and interaction with lipids and proteins.

scientific article published on 28 December 2013

Long endogenous dsRNAs can induce complete gene silencing in mammalian cells and primary cultures.

scientific article published on January 2003

Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6.

scientific article published in January 2012

Manumycin A and its analogues are irreversible inhibitors of neutral sphingomyelinase

scientific article published on 01 February 2001

MicroRNA maturation and human disease.

scientific article published on January 2014

MicroRNA-145-targeted drug and its preventive effect on pulmonary arterial hypertension (patent WO2012153135 A1).

scientific article published on 18 March 2015

Perspectives in targeting miRNA function.

scientific article published on 02 April 2013

Phosphatidylinositol-3,5-Bisphosphate Is a Potent and Selective Inhibitor of Acid Sphingomyelinase

scientific article published on September 1, 2003

Potent and selective inhibition of acid sphingomyelinase by bisphosphonates

scientific article published on 01 January 2009

Potent inhibition of acid sphingomyelinase by phosphoinositide analogues.

scientific article

RNA Interference: Analyzing the Function of Glycoproteins and Glycosylating Proteins in Mammalian Cells

scientific article published on January 1, 2003

RNA interference: from an ancient mechanism to a state of the art therapeutic application?

scientific article published on 23 July 2003

Recent advances and novel treatments for sphingolipidoses

scientific article published on 31 August 2017

Regioselective Diazo-Transfer Reaction at the C3-Position of the 2-Desoxystreptamine Ring of Neamine Antibiotics

scientific article published on 27 May 2013

Rolling-circle amplification: unshared advantages in miRNA detection.

scientific article published in May 2009

SERS and Cryo-EM Directly Reveal Different Liposome Structures during Interaction with Gold Nanoparticles

scientific article published on 15 November 2018

Small molecule inhibitors of acid sphingomyelinase.

scientific article published on 18 May 2010

Small molecule inhibitors of ceramidases.

scientific article

Sphingolipid-Transporting Proteins as Cancer Therapeutic Targets

scientific article published on 20 July 2019

Structural insights into adiponectin receptors suggest ceramidase activity.

scientific article published on 22 March 2017

Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy

scientific article published in Nature Communications

Subunit composition of the mammalian serine-palmitoyltransferase defines the spectrum of straight and methyl-branched long-chain bases

scientific article published on 23 June 2020

Synthesis and biochemical investigation of scyphostatin analogues as inhibitors of neutral sphingomyelinase.

scientific article

Synthesis and characterization of some atypical sphingoid bases

scientific article published on 23 June 2018

Synthesis of the First Selective Irreversible Inhibitor of Neutral Sphingomyelinase This work was supported by grants from the Fonds der Chemischen Industrie. C.A. is grateful to the Land of Baden-Württemberg for a scholarship from the Landesgraduie

scientific article published on 01 April 2000

The cellular ceramide transport protein CERT promotes Chlamydia psittaci infection and controls bacterial sphingolipid uptake.

scientific article published on 19 May 2017

Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase

scientific article published on September 2013

Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway

scientific article published on 28 August 2018

miRNAs as novel therapeutic targets and diagnostic biomarkers for Parkinson's disease: a patent evaluation of WO2014018650.

scientific article