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List of works by Masahiko Negishi

A role of Lys614 in the sulfotransferase activity of human heparan sulfate N‐deacetylase/N‐sulfotransferase

scientific article published on August 21, 1998

Activation by Diverse Xenochemicals of the 51-Base Pair Phenobarbital-Responsive Enhancer Module in theCYP2B10Gene

scientific article published on April 1, 1998

Active ERK1/2 Protein Interacts with the Phosphorylated Nuclear Constitutive Active/Androstane Receptor (CAR; NR1I3), Repressing Dephosphorylation and Sequestering CAR in the Cytoplasm

scientific article published on August 26, 2011

Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: Steroid-binding site and orientation

scientific article published on December 1, 1992

Are estrogens carcinogenic during development of the testes?

scientific article published on January 1, 1998

Biosynthesis of cytochrome P-450 on membrane-bound ribosomes and its subsequent incorporation into rough and smooth microsomes in rat hepatocytes

scientific article published on June 1, 1979

Conserved structural motifs in the sulfotransferase family

scientific article published on 01 April 1998

Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system

scientific article

Crystal structure of estrogen sulphotransferase

scientific article published on November 1, 1997

Cytoplasmic Accumulation of the Nuclear Receptor CAR by a Tetratricopeptide Repeat Protein in HepG2 Cells

scientific article published on November 1, 2003

Distribution and induction of cytochrome P-450 in rat liver nuclear envelope

scientific article published on October 1, 1981

Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity

scientific article

Expression and subcellular distribution of mouse cytochrome P1-450 mRNA as determined by molecular hybridization with cloned P1-450 DNA

scientific article published on January 29, 1982

Garlic Extract Diallyl Sulfide (DAS) Activates Nuclear Receptor CAR to Induce the Sult1e1 Gene in Mouse Liver

scientific article published on June 15, 2011

Genetic regulation of testosterone 15 alpha-hydroxylase (cytochrome P-450(15)alpha) in renal microsomes of female mice

scientific article published in August 1986

Induction of Human CYP2C9 by Rifampicin, Hyperforin, and Phenobarbital Is Mediated by the Pregnane X Receptor

scientific article published on November 4, 2003

Isolation and characterization of a cloned DNA sequence associated with the murine Ah locus and a 3-methylcholanthrene-induced form of cytochrome P -450

scientific article published on February 1, 1981

Liganded pregnane X receptor represses the human sulfotransferase SULT1E1 promoter through disrupting its chromatin structure

scientific article published on July 14, 2011

Localization of nascent NADPH-cytochrome c reductase in rat liver microsomes

scientific article published on January 13, 1975

Molecular Cloning and Characterization of a Novel Nuclear Protein Kinase in Mice

scientific article published on April 1, 1998

Molecular characterization of the murine Coh locus: an amino acid difference at position 117 confers high and low coumarin 7-hydroxylase activity in P450coh

scientific article published on 01 February 1992

Mouse Glycine N-Methyltransferase is Sexually Dimorphic and Regulated by Growth Hormone

scientific article published on December 1, 1997

Mouse pulmonary cytochrome P-450 naphthalene hydroxylase: cDNA cloning, sequence, and expression in Saccharomyces cerevisiae

scientific article published on December 3, 1991

Multiple forms of cytochrome P-450 and the importance of molecular biology and evolution

scientific article published on July 15, 1982

Nuclear Receptor CAR Specifically Activates the Two-Pore K+ Channel Kcnk1 Gene in Male Mouse Livers, Which Attenuates Phenobarbital-Induced Hepatic Hyperplasia

scientific article published on January 4, 2013

Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver

scientific article published on August 8, 2011

Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B

scientific article

Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors

scientific article published on March 17, 2011

Phenobarbital Meets Phosphorylation of Nuclear Receptors

scientific article

Pregnane X receptor regulates drug metabolism and transport in the vasculature and protects from oxidative stress

scientific article published on 13 December 2011

Presence of Apo-cytochrome b5 in Microsomes from Rat Liver*

scientific article published on 01 May 1970

Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes

scientific article published on March 1, 1998

Purification and Partial Characterization of Hepatic Microsomal Cytochrome P-450s from Phenobarbital-and 3-Methylcholanthrene-Treated Rats1

scientific article published on November 1, 1979

Regulatory DNA elements of phenobarbital-responsive cytochrome P450 CYP2B genes

scientific article published on January 1, 1998

Role of a novel CAR-induced gene, TUBA8, in hepatocellular carcinoma cell lines

scientific article published on July 1, 2011

Roles of residues 129 and 209 in the alteration by cytochrome b5 of hydroxylase activities in mouse 2A P450S

scientific article published on November 24, 1992

Separation of acetanilide and its hydroxylated metabolites and quantitative determination of "acetanilide 4-hydroxylase activity" by high-pressure liquid chromatography

scientific article published on July 1, 1979

Steroid hormone-dependent overexpression of cytochromes P450 2A in liver tumors of TGFα transgenic male mice

scientific article published on October 1, 1997

The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA

scientific article published on 01 November 1982

The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the CYP2B Gene

scientific article published on October 1, 1998

The Structural Basis for a Coordinated Reaction Catalyzed by a Bifunctional Glycosyltransferase in Chondroitin Biosynthesis

scientific article published on August 30, 2012

The Structure, Function, and Regulation of Cytochrome P450 2A Enzymes

scientific article published on November 1, 1997

Transcriptional regulation by HNF-4 of the steroid 15α-hydroxylase P450 (Cyp2a-4) gene in mouse liver

scientific article published on July 1, 1997