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List of works by Meredith L Jenkins

An intrinsic lipid-binding interface controls sphingosine kinase 1 function

scientific article published on 11 January 2018

An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery

scientific article published on 3 August 2017

Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1.

scientific article published on 6 February 2017

Dissecting the molecular assembly of the Toxoplasma gondii MyoA motility complex

scientific article published on 25 September 2017

Expanding the Scope of Electrophiles Capable of Targeting K-Ras Oncogenes.

scientific article published on 16 June 2017

Molecular basis for recognition of the cancer glycobiomarker LacdiNAc (GalNAc(β1-4)GlcNAc) by Wisteria floribunda agglutinin

scientific article

Molecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11

scientific article published in 2023

Molecular mechanism of activation of class IA phosphoinositide 3-kinases (PI3Ks) by membrane-localized HRas

scientific article published on 17 May 2017

Novel K-Ras G12C Switch-II covalent binders destabilize Ras and accelerate nucleotide exchange

scientific article published on 10 January 2018

Novel PIK3CD mutations affecting N-terminal residues of p110δ cause activated PI3Kδ syndrome (APDS) in humans

scientific article published on 13 April 2017

Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States

scientific article published on 19 September 2017

Recognition of protein-linked glycans as a determinant of peptidase activity

scientific article published on 17 January 2017

Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5

scientific article published in Nature Communications

The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3.

scientific article published on 7 December 2016

Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIIIβ with Rab11

scientific article