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List of works by Brian O'Rourke

Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models

scientific article published on 22 March 2018

An integrated mitochondrial ROS production and scavenging model: implications for heart failure

scientific article published on December 2013

Cardiac mitochondria exhibit dynamic functional clustering

scientific article

Cardiac mitochondrial network excitability: insights from computational analysis ⬇️

scientific article published on March 16, 2012

Cardiac resynchronization therapy restores sympathovagal balance in the failing heart by differential remodeling of cholinergic signaling

scientific article published on 2 March 2015

Dynamic modulation of Ca2+ sparks by mitochondrial oscillations in isolated guinea pig cardiomyocytes under oxidative stress ⬇️

scientific article published on May 27, 2011

From bioblasts to mitochondria: ever expanding roles of mitochondria in cell physiology ⬇️

scientific article published on June 15, 2010

Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative

scientific article

Impaired mitochondrial network excitability in failing guinea-pig cardiomyocytes

scientific article

Inhibiting mitochondrial Na+/Ca2+ exchange prevents sudden death in a Guinea pig model of heart failure

scientific article

Integrative modeling of the cardiac ventricular myocyte ⬇️

scientific article published on September 23, 2010

Metabolic control analysis applied to mitochondrial networks ⬇️

scientific article published on January 1, 2011

Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondria

scientific article published in 2014

Mitochondria are sources of metabolic sink and arrhythmias ⬇️

scientific article published on April 14, 2011

Mitochondrial networks in cardiac myocytes reveal dynamic coupling behavior

scientific article published on April 2015

Myocardial oxidative stress correlates with left ventricular dysfunction on strain echocardiography in a rodent model of sepsis

scientific article

Na+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes

scientific article

Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy ⬇️

scientific article published in January 2017

Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling

scientific article

Parallel proteomics to improve coverage and confidence in the partially annotated Oryctolagus cuniculus mitochondrial proteome ⬇️

scientific article published on October 29, 2010

TNNT2 mutations in the tropomyosin binding region of TNT1 disrupt its role in contractile inhibition and stimulate cardiac dysfunction

scientific article published on 20 July 2020

Wavelet analysis reveals heterogeneous time-dependent oscillations of individual mitochondria ⬇️

scientific article published on September 10, 2010

What yeast and cardiomyocytes share: ultradian oscillatory redox mechanisms of cellular coherence and survival ⬇️

scientific article published on December 5, 2011

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