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List of works by Jean-Luc Puel

A computational model of the primary auditory neuron activity.

scientific article published in January 2010

A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice

scientific article published on 14 June 2022

A new hope: restoration of auditory evoked responses

scientific article published on 28 February 2013

A novel dual inhibitor of calpains and lipid peroxidation (BN82270) rescues the cochlea from sound trauma.

scientific article published on 7 March 2007

A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss.

scientific article

AMPA-preferring glutamate receptors in cochlear physiology of adult guinea-pig.

scientific article published in August 1999

Actin Filaments Regulate Exocytosis at the Hair Cell Ribbon Synapse.

scientific article

Age-related Changes in Auditory Cortex Without Detectable Peripheral Alterations: A Multi-level Study in Sprague-Dawley Rats

scientific article published on 12 February 2019

Alterations in Regional Homogeneity in Patients With Unilateral Chronic Tinnitus

scientific article published on 01 January 2019

Antisense oligonucleotides to the GluR2 AMPA receptor subunit modify excitatory synaptic transmission in vivo ⬇️

scientific article published on March 30, 1998

Assessment of cochlear effects and extra-auditory disorders in male rats exposed repetitively to low noise

scientific article published in December 2015

Benefit of Preoperative Temporal Bone CT for Atraumatic Cochlear Implantation.

scientific article published on 16 January 2018

Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity.

scientific article published on 13 November 2006

Caspase inhibitors, but not c-Jun NH2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss.

scientific article published in December 2004

Changes in 2f1-f2 distortion product otoacoustic emissions following alterations of cochlear metabolism.

scientific article published in April 1993

Characteristics of tinnitus and etiology of associated hearing loss: a study of 123 patients.

scientific article

Clinical and angiographic outcome of paclitaxel-eluting stent implantation for unprotected left main coronary artery bifurcation narrowing.

scientific article published in February 2006

Cochlear NMDA receptor blockade prevents salicylate-induced tinnitus.

scientific article published on January 2007

Cochlear efferents in developing adult and pathological conditions.

scientific article published on 26 March 2015

Cochlear neuropathy in the rat exposed for a long period to moderate-intensity noises

scientific article published on 3 February 2015

Cochlear origin of 2f1-f2 distortion products assessed by using 2 types of mutant mice

scientific article published on 01 March 1991

Comparison of three spike detectors dedicated to single unit action potentials of the auditory nerve.

scientific article published in January 2007

Contribution of auditory nerve fibers to compound action potential of the auditory nerve

scientific article published on 21 May 2014

Control of hair cell excitability by vestibular primary sensory neurons

scientific article

Correlative development of cochlear action potential sensitivity, latency, and frequency selectivity.

scientific article

Coxsackie adenovirus receptor and alpha nu beta3/alpha nu beta5 integrins in adenovirus gene transfer of rat cochlea.

scientific article published on 3 August 2006

Deafness and cochlear fibrocyte alterations in mice deficient for the inner ear protein otospiralin.

scientific article

Degeneration of sensory outer hair cells following pharmacological blockade of cochlear KCNQ channels in the adult guinea pig.

scientific article

Development of 2f1-f2 otoacoustic emissions in the rat

scientific article published on 01 January 1987

Differential expression of PKC beta II in the rat organ of Corti.

scientific article

Dopamine inhibition of auditory nerve activity in the adult mammalian cochlea.

scientific article

Dopamine transporter is essential for the maintenance of spontaneous activity of auditory nerve neurones and their responsiveness to sound stimulation.

scientific article published on 8 March 2006

Dose-dependent changes in the rat cochlea following aminoglycoside intoxication. II. Histological study.

scientific article

Downregulation of otospiralin, a novel inner ear protein, causes hair cell degeneration and deafness

scientific journal article

Drug-eluting or bare-metal stents in subjects over 75 years of age: what is the best therapeutic strategy? Data from 460 consecutive patients with 1-year outcome.

scientific article

Effect of contralateral sound stimulation on the distortion product 2F1-F2: evidence that the medial efferent system is involved.

scientific article published on April 1990

Effects of a dopaminergic agonist in the guinea pig cochlea

scientific article published on 01 October 1995

Efficient and specific transduction of cochlear supporting cells by adeno-associated virus serotype 5.

scientific article published on 26 June 2008

Electrical stimulation activates two different sites within the guinea pig cochlea.

scientific article published in October 1996

Electrophysiological evidence for the presence of NMDA receptors in the guinea pig cochlea ⬇️

scientific article published on February 1, 1991

Epithelial-mesenchymal transition, and collective and individual cell migration regulate epithelial changes in the amikacin-damaged organ of Corti

scientific article published in April 2017

Evaluation of otoscopy simulation as a training tool for real-time remote otoscopy.

scientific article published on 19 December 2017

Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity.

scientific article published in March 1994

Excitotoxicity and repair of cochlear synapses after noise-trauma induced hearing loss.

scientific article published in June 1998

FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear.

scientific article published on 5 January 2007

From cochlear cell death pathways to new pharmacological therapies.

scientific article published on September 2008

Functional properties of the crossed part of the medial olivo-cochlear bundle

scientific article published on 01 January 1987

Glutamate transporters in the guinea-pig cochlea: partial mRNA sequences, cellular expression and functional implications.

scientific article

High mobility group box 1 (HMGB1): dual functions in the cochlear auditory neurons in response to stress?

scientific article published on 4 October 2016

Identification and modelling of fast and slow Ih current components in vestibular ganglion neurons.

scientific article

Impairment of SLC17A8 encoding vesicular glutamate transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice.

scientific article

Implication of nmda type glutamate receptors in neural regeneration and neoformation of synapses after excitotoxic injury in the guinea pig cochlea ⬇️

scientific article published on July 1, 1997

Impulse Noise Induced Hidden Hearing Loss, Hair Cell Ciliary Changes and Oxidative Stress in Mice

scientific article published in 2021

Inhibition of the c-Jun N-terminal kinase-mediated mitochondrial cell death pathway restores auditory function in sound-exposed animals.

scientific article published on 28 November 2006

Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing

scientific journal article

Loss of function of Ywhah in mice induces deafness and cochlear outer hair cells' degeneration.

scientific article

Macrophage contribution to the response of the rat organ of Corti to amikacin.

scientific article published in July 2007

Mass Potentials Recorded at the Round Window Enable the Detection of Low Spontaneous Rate Fibers in Gerbil Auditory Nerve.

scientific article

Medial olivocochlear efferent activity in awake guinea pigs.

scientific article

Microtubule-associated protein 2 (MAP2) expression during synaptic plasticity in the guinea pig cochlea.

scientific article

Molecular and cellular mechanisms of loss of residual hearing after cochlear implantation.

scientific article published on January 2013

Neuroprotective effect of riluzole in acute noise-induced hearing loss.

scientific article published in July 2005

New pharmacological strategies to restore hearing and treat tinnitus.

scientific article published in May 2004

OPA1 R445H mutation in optic atrophy associated with sensorineural deafness.

scientific article published in December 2005

Oxidative stress, inflammation, and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse Cochlea.

scientific article published in December 2011

Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.

scientific article published on 16 February 2017

Peristimulus Time Responses Predict Adaptation and Spontaneous Firing of Auditory-Nerve Fibers: From Rodents Data to Humans

scientific article published in 2022

Pharmacological strategies for preventing cochlear damage induced by noise trauma.

scientific article

Presbycusis: An Update on Cochlear Mechanisms and Therapies

scientific article published on 14 January 2020

Prevention of trauma-induced cochlear fibrosis using intracochlear application of anti-inflammatory and antiproliferative drugs.

scientific article published on 21 December 2015

Protein kinase C may be involved in synaptic repair of auditory neuron dendrites after AMPA injury in the cochlea.

scientific article published in February 1997

ROS-Induced Activation of DNA Damage Responses Drives Senescence-Like State in Postmitotic Cochlear Cells: Implication for Hearing Preservation

scientific article published on 28 January 2019

Recovery of auditory-nerve-fiber spike amplitude under natural excitation conditions

scientific article published on 25 August 2018

Remodeling of the Inner Hair Cell Microtubule Meshwork in a Mouse Model of Auditory Neuropathy AUNA1.

scientific article

Reversible p53 inhibition prevents cisplatin ototoxicity without blocking chemotherapeutic efficacy

scientific article

Riluzole rescues cochlear sensory cells from acoustic trauma in the guinea-pig.

scientific article published in January 2002

Salicylate enables cochlear arachidonic-acid-sensitive NMDA receptor responses.

scientific article published in July 2008

Salicylate induces tinnitus through activation of cochlear NMDA receptors

scientific article (publication date: May 2003)

Salicylate-induced tinnitus: molecular mechanisms and modulation by anxiety.

scientific article published on January 2007

Selective attention modifies the active micromechanical properties of the cochlea

scientific article published on 01 May 1988

Sound Coding in the Auditory Nerve: From Single Fiber Activity to Cochlear Mass Potentials in Gerbils

scientific article published on 17 October 2018

Sound coding in the auditory nerve of gerbils.

scientific article published on 21 May 2016

Spatiotemporal pattern of action potential firing in developing inner hair cells of the mouse cochlea

scientific article

Spiking Pattern of the Mouse Developing Inner Hair Cells Is Mostly Invariant Along the Tonotopic Axis

scientific article published on 14 November 2018

Supporting cells regulate the remodelling of aminoglycoside-injured organ of Corti, through the release of high mobility group box 1.

scientific article published on 8 July 2013

Suppression of auditory nerve activity in the guinea pig cochlea by 1-(p-bromobenzoyl)-piperazine-2,3-dicarboxylic acid.

scientific article

Synaptic connections and putative functions of the dopaminergic innervation of the guinea pig cochlea.

scientific article

Synaptic regeneration and functional recovery after excitotoxic injury in the guinea pig cochlea

scientific article published on 01 January 1995

Synaptic repair mechanisms responsible for functional recovery in various cochlear pathologies.

scientific article

The Interplay Between Spike-Time and Spike-Rate Modes in the Auditory Nerve Encodes Tone-In-Noise Threshold

scientific article published on 23 May 2018

The human OPA1delTTAG mutation induces premature age-related systemic neurodegeneration in mouse.

scientific article published in December 2012

The inner hair cell synaptic complex: physiology, pharmacology and new therapeutic strategies.

scientific article published on January 2002

The risks of amplified music for disc-jockeys working in nightclubs.

scientific article

Tmprss3 loss of function impairs cochlear inner hair cell Kcnma1 channel membrane expression

scientific article

Tmprss3, a transmembrane serine protease deficient in human DFNB8/10 deafness, is critical for cochlear hair cell survival at the onset of hearing

scientific article

Toward Cochlear Therapies

scientific article published on 01 October 2018

Transient Ca2+-permeable AMPA receptors in postnatal rat primary auditory neurons.

scientific article published in December 2004

Ultrastructure of the Odontocete organ of Corti: scanning and transmission electron microscopy

scientific article

Validation of the French-language version of the OTOSPEECH automated scoring software package for speech audiometry.

scientific article published on 12 February 2016

[Treatment of tinnitus. New perspectives]

scientific article published on 01 July 2002

m-Chlorophenylpiperazine exacerbates perception of salicylate-induced tinnitus in rats.

scientific article published in November 2005

rAAV-Mediated Cochlear Gene Therapy: Prospects and Challenges for Clinical Application

scientific article published on 21 February 2020

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