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List of works by Xiaofeng Zhu

A Generalized Sequential Bonferroni Procedure for GWAS in Admixed Populations Incorporating Admixture Mapping Information into Association Tests

scientific article published on 13 June 2015

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A candidate gene study of obstructive sleep apnea in European Americans and African Americans

scientific article

A classical likelihood based approach for admixture mapping using EM algorithm.

scientific article published on 5 August 2006

A combinatorial searching method for detecting a set of interacting loci associated with complex traits.

scientific article published in September 2006

A combined analysis of genomewide linkage scans for body mass index from the National Heart, Lung, and Blood Institute Family Blood Pressure Program

scientific article published on 28 March 2002

A common genetic variant is associated with adult and childhood obesity

scientific article

A genome scan among Nigerians linking resting energy expenditure to chromosome 16.

scientific article

A genome-wide linkage and association study using COGA data.

scientific article

A genome-wide linkage study of GAW15 gene expression data.

scientific article

A genome-wide scan for body mass index among Nigerian families

scientific article published in February 2003

A genome-wide scan of loci linked to serum adiponectin in two populations of African descent

scientific article published in May 2007

A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE) unlinked to the ACE gene

scientific article published on 10 June 2008

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

scientific article

A novel method to detect rare variants using both family and unrelated case-control data ⬇️

scientific article published on November 29, 2011

A test of transmission/disequilibrium for quantitative traits in pedigree data, by multiple regression

scientific article

A unified GMDR method for detecting gene-gene interactions in family and unrelated samples with application to nicotine dependence

scientific article published on 21 September 2013

A unified association analysis approach for family and unrelated samples correcting for stratification.

scientific article published on February 2008

A variance component based multi-marker association test using family and unrelated data.

scientific article

Adjustment for covariates using summary statistics of genome-wide association studies

scientific article published on 20 September 2018

Adjustment for local ancestry in genetic association analysis of admixed populations ⬇️

scientific article published on December 17, 2010

Admixture mapping for hypertension loci with genome-scan markers

scientific article

Admixture mapping identifies novel loci for obstructive sleep apnea in hispanic/latino americans

scientific article published on 01 February 2019

Admixture mapping provides evidence of association of the VNN1 gene with hypertension

scientific article

Allowing for Population Stratification in Association Analysis ⬇️

scientific article published on January 1, 2012

An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group

scientific article published on 27 May 2016

An association study of angiotensinogen polymorphisms with serum level and hypertension in an African-American population

scientific article published on 01 October 2003

Analysis of exome sequences with and without incorporating prior biological knowledge.

scientific article published on January 2011

Analytical correction for multiple testing in admixture mapping.

scientific article published on 12 October 2006

Angiotensin I-converting enzyme polymorphisms, ACE level and blood pressure among Nigerians, Jamaicans and African-Americans

scientific article

Angiotensin-converting enzyme gene polymorphisms and obesity: an examination of three black populations

scientific article published in May 2005

Association Studies of BMI and Type 2 Diabetes in the Neuropeptide Y Pathway: A Possible Role for NPY2R as a Candidate Gene for Type 2 Diabetes in Men

article

Association between evolutionary history of angiotensinogen haplotypes and plasma levels

scientific article published in September 2004

Association mapping, using a mixture model for complex traits

scientific article published on 01 August 2002

Association of genetic loci with sleep apnea in European Americans and African-Americans: the Candidate Gene Association Resource (CARe).

scientific article

Association of genetic variation with blood pressure traits among East Africans.

scientific article published on 20 January 2017

Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study

scientific article

Association of regions on chromosomes 6 and 7 with blood pressure in Nigerian families

scientific article published on 23 January 2009

Associations between hypertension and genes in the renin-angiotensin system.

scientific article published on 14 April 2003

Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep

scientific article published on 16 April 2019

Calibrating Population Stratification in Association Analysis.

scientific article

Capability of common SNPs to tag rare variants.

scientific article

Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium

scientific article

Combined analysis of genomewide scans for adult height: results from the NHLBI Family Blood Pressure Program

scientific article published on March 2003

Combined linkage and association analysis identifies rare and low frequency variants for blood pressure at 1q31

scientific article published on 27 September 2018

Common Variants in the ENPP1 Gene Are Not Reproducibly Associated With Diabetes or Obesity

article

Comparison of Heritability Estimation and Linkage Analysis for Multiple Traits Using Principal Component Analyses

scientific article published on April 2016

Correction: Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry.

scientific article published on 21 November 2011

Cross-Phenotype Association Analysis Using Summary Statistics from GWAS.

scientific article published in January 2017

De novo mutations discovered in 8 Mexican American families through whole genome sequencing

scientific article

Detecting Multiethnic Rare Variants.

scientific article published in January 2017

Detecting fitness epistasis in recently admixed populations with genome-wide data

scientific article published on 11 July 2020

Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS).

scientific article

Detecting rare variants.

scientific article published on January 2012

Determinants of hypertension in a young adult Ugandan population in epidemiological transition-the MEPI-CVD survey

scientific article published on 28 August 2015

Diminished induction of skin fibrosis in mice with MCP-1 deficiency

scientific article published on 11 May 2006

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

scientific article

Discovery of common sequences absent in the human reference genome using pooled samples from next generation sequencing

scientific article

EINVis: a visualization tool for analyzing and exploring genetic interactions in large-scale association studies

scientific article published on 11 August 2013

Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium

scientific article

Erythrocyte sodium-lithium countertransport and blood pressure: a genome-wide linkage study

scientific article published on 23 December 2002

Evaluation of a LASSO regression approach on the unrelated samples of Genetic Analysis Workshop 17.

scientific article

GEE-based SNP set association test for continuous and discrete traits in family-based association studies

scientific article

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

Gene Mapping in Admixed Families: A Cautionary Note on the Interpretation of the Transmission Disequilibrium Test and a Possible Solution

scientific article published on 12 January 2017

Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data.

scientific article

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Gene-gene and gene-environment interactions in ulcerative colitis.

scientific article

Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans

scientific article

Genetic effects on blood pressure localized to chromosomes 6 and 7.

scientific article published in July 2005

Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genome scan among Nigerians linking blood pressure to chromosomes 2, 3, and 19.

scientific article published in November 2002

Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits

scientific article published on 19 December 2016

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations

scientific article

Genome-wide association analysis of excessive daytime sleepiness identifies 42 loci that suggest phenotypic subgroups

Genome-wide association of anthropometric traits in African- and African-derived populations

scientific article

Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection

scientific article

Genome-wide distribution of ancestry in Mexican Americans.

scientific article

Genomic regions associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma in African Americans: The cross BETRNet admixture study.

scientific article published on 26 October 2017

Haplotypes produced from rare variants in the promoter and coding regions of angiotensinogen contribute to variation in angiotensinogen levels

article published in 2005

Height associated variants demonstrate assortative mating in human populations.

scientific article published on 16 November 2017

Heritability of obesity-related traits among Nigerians, Jamaicans and US black people

scientific article

Heterogeneity in older people: examining physiologic failure, age, and comorbidity

scientific article published on 01 December 2002

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry

scientific article

Identifying Rare Variant Associations in Admixed Populations

scientific article published on 01 April 2019

Identifying rare variants from exome scans: the GAW17 experience

scientific article

Improving power in contrasting linkage-disequilibrium patterns between cases and controls.

scientific article published on 28 March 2007

Interrogating local population structure for fine mapping in genome-wide association studies.

scientific article

Interrogating population structure and its impact on association tests ⬇️

scientific article published on November 29, 2011

Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data

scientific article published on 22 January 2019

Linkage analysis of a complex disease through use of admixed populations.

scientific article

Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure

scientific article

Linkage disequilibrium analysis of the renin-angiotensin system genes.

scientific article

Linkage for BMI at 3q27 region confirmed in an African-American population.

scientific article published in May 2003

Linkage-Disequilibrium-Based Binning Misleads the Interpretation of Genome-wide Association Studies ⬇️

scientific article published on November 2, 2012

Loci influencing blood pressure identified using a cardiovascular gene-centric array

scientific article published on 8 January 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

scientific article

Meta-analysis of correlated traits via summary statistics from GWASs with an application in hypertension

scientific article

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

scientific article published in Nature Communications

Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.

scientific article

Multivariate Analysis of Anthropometric Traits Using Summary Statistics of Genome-Wide Association Studies from GIANT Consortium

scientific article

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Pathway-based analysis for genome-wide association studies using supervised principal components.

scientific article

Power comparison of admixture mapping and direct association analysis in genome-wide association studies.

scientific article published on 28 March 2012

Qualitative semi-parametric test for genetic associations in case-control designs under structured populations.

scientific article published in May 2003

Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans.

scientific article published on 5 May 2006

Rare variant density across the genome and across populations ⬇️

scientific article published on November 29, 2011

Rare variants in fox-1 homolog A (RBFOX1) are associated with lower blood pressure.

scientific article

Refinement of the DFNA41 locus and candidate genes analysis.

scientific article published on 30 September 2005

Sequential gene expression profiling in lung transplant recipients with chronic rejection

scientific article published on 01 September 2006

Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

scientific article

Statistical interaction in human genetics: how should we model it if we are looking for biological interaction? ⬇️

scientific article published on November 23, 2010

Study of the relationship between the interleukin-6 gene and obstructive sleep apnea.

scientific article

Testing gene-environment interactions in gene-based association studies ⬇️

scientific article published on November 29, 2011

The Analysis of Ethnic Mixtures

scientific article

The Meaning of Interaction ⬇️

scientific article published on December 8, 2010

The analysis of ethnic mixtures

scientific article published on January 2012

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts

scientific article

The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function

scientific article

The effect of MCP-1 depletion on chemokine and chemokine-related gene expression: evidence for a complex network in acute inflammation

scientific article published on 01 April 2005

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The landscape of recombination in African Americans

scientific article

The power of genetic diversity in genome-wide association studies of lipids

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

scientific article

Transferability of tag SNPs in genetic association studies in multiple populations

scientific article published on 22 October 2006

Two-marker association tests yield new disease associations for coronary artery disease and hypertension ⬇️

scientific article published on May 28, 2011

Using the optimal robust receiver operating characteristic (ROC) curve for predictive genetic tests.

scientific article

VarExp: estimating variance explained by genome-wide GxE summary statistics

scientific article published on 01 October 2018

Variants in angiopoietin-2 (ANGPT2) contribute to variation in nocturnal oxyhaemoglobin saturation level

scientific article

What is the significance of difference in phenotypic variability across SNP genotypes?

scientific article published on August 2013

Whole genome sequencing data from pedigrees suggests linkage disequilibrium among rare variants created by population admixture.

scientific article

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