List of works by Dana Crawford

A Social Determinant of Health May Modify Genetic Associations for Blood Pressure: Evidence From a SNP by Education Interaction in an African American Population

A common VLDLR polymorphism interacts with APOE genotype in the prediction of carotid artery disease risk

scientific article

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

scientific article

A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes

scientific article published on 18 November 2011

A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans

scientific article published on 31 December 2019

A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study.

scientific article

Accuracy of administratively-assigned ancestry for diverse populations in an electronic medical record-linked biobank ⬇️

scientific article

Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans

scientific article

Allelic spectrum of the natural variation in CRP.

scientific article

Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records

scientific article

Assessment of a pharmacogenomic marker panel in a polypharmacy population identified from electronic medical records

scientific article published on May 2013

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

scientific article published on 23 December 2011

Association of cancer susceptibility variants with risk of multiple primary cancers: The population architecture using genomics and epidemiology study

scientific article

Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study

scientific article

Association of the FTO obesity risk variant rs8050136 with percentage of energy intake from fat in multiple racial/ethnic populations: the PAGE study

scientific article published on 02 July 2013

Atopy history and the genomics of wheezing after influenza vaccination in children 6-59 months of age.

scientific article published on 9 March 2011

Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network

scientific article

CRP polymorphisms and chronic kidney disease in the third national health and nutrition examination survey.

scientific article

CRP polymorphisms and progression of chronic kidney disease in African Americans

scientific article

Characterization of beta-globin haplotypes using blood spots from a population-based cohort of newborns with homozygous HbS.

scientific article published in September 2002

Characterization of genome-wide association-identified variants for atrial fibrillation in African Americans

scientific article published on 23 February 2012

Characterization of mitochondrial haplogroups in a large population-based sample from the United States

scientific article

Characterization of the Metabochip in diverse populations from the International HapMap Project in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project

scientific article published on January 2013

Conference Scene: Lessons learned from the 5th Statistical Analysis Workshop of the Pharmacogenetics Research Network

scientific article published on 01 March 2010

Consistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) Consortium

scientific article

Controlling for population structure and genotyping platform bias in the eMERGE multi-institutional biobank linked to electronic health records

scientific article

Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia

scientific article

Cryptic relatedness in epidemiologic collections accessed for genetic association studies: experiences from the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) study and the National Health and Nutrition Examination Surveys (NHANE

scientific article

DEVELOPMENT AND PERFORMANCE OF TEXT-MINING ALGORITHMS TO EXTRACT SOCIOECONOMIC STATUS FROM DE-IDENTIFIED ELECTRONIC HEALTH RECORDS.

scientific article published on January 2016

DRUG-DRUG INTERACTION PROFILES OF MEDICATION REGIMENS EXTRACTED FROM A DE-IDENTIFIED ELECTRONIC MEDICAL RECORDS SYSTEM

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Definition and clinical importance of haplotypes

scientific article

Detecting and Characterizing Pleiotropy: New Methods for Uncovering the Connection Between the Complexity of Genomic Architecture and Multiple phenotypes

scientific article published on January 2014

Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study

scientific article

Development of a data-mining algorithm to identify ages at reproductive milestones in electronic medical records

scientific article

Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study

scientific article published on 01 August 2018

Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study

scientific article

Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study

scientific article (publication date: 2013)

Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank

scientific article

Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study

scientific article

Evidence for age as a modifier of genetic associations for lipid levels

scientific article

Evidence for extensive pleiotropy among pharmacogenes

scientific article published on June 2016

Evidence for substantial fine-scale variation in recombination rates across the human genome

scientific article published on 06 June 2004

Extracting Country-of-Origin from Electronic Health Records for Gene- Environment Studies as Part of the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) Study

scientific article

Extracting Primary Open-Angle Glaucoma from Electronic Medical Records for Genetic Association Studies

scientific article published on 10 June 2015

Extraction of echocardiographic data from the electronic medical record is a rapid and efficient method for study of cardiac structure and function

scientific article

FMR1 and the fragile X syndrome: human genome epidemiology review

scientific article

Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin

scientific article published on July 2011

Factors involved in the initial mutation of the fragile X CGG repeat as determined by sperm small pool PCR

scientific article published on 01 November 2000

Fine Mapping and Identification of BMI Loci in African Americans

scientific article published on October 2013

Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations

scientific article

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

scientific article

Frequency and phenotype consequence of APOC3 rare variants in patients with very low triglyceride levels

Gene-carbohydrate and gene-fiber interactions and type 2 diabetes in diverse populations from the National Health and Nutrition Examination Surveys (NHANES) as part of the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) study

scientific article

Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study

scientific article

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans

scientific article published on 28 March 2013

Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study

scientific article

Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study

scientific article

Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium

scientific article published on 2 February 2012

Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study

scientific article

Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network

scientific article

Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network

scientific article published on 30 October 2011

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

scientific article published on 05 June 2013

Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study

scientific article published on 08 July 2013

Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study

scientific article

Genetic variation associated with circulating monocyte count in the eMERGE Network

scientific article published on 12 January 2013

Genetic variation in donor CTLA-4 regulatory region is a strong predictor of outcome after allogeneic hematopoietic cell transplantation for hematologic malignancies

article

Genetic variation in recipient B-cell activating factor modulates phenotype of GVHD.

scientific article published on 31 May 2011

Genetic variation in the HLA region is associated with susceptibility to herpes zoster

scientific article

Genetic variation in the rhythmonome: ethnic variation and haplotype structure in candidate genes for arrhythmias

scientific article

Genetic variation in the β1-adrenergic receptor is associated with the risk of atrial fibrillation after cardiac surgery.

scientific article

Genetic variation is associated with C-reactive protein levels in the Third National Health and Nutrition Examination Survey

scientific article

Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes

scientific article (publication date: 2013)

Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk

scientific article published on 05 March 2013

Genome-Wide Association Study of Serum Creatinine Levels during Vancomycin Therapy

scientific article published on June 2015

Genome-wide association analysis of common genetic variants of resistant hypertension

scientific article published on 20 September 2018

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide study of resistant hypertension identified from electronic health records

scientific article

Genotype imputation of Metabochip SNPs using a study-specific reference panel of ~4,000 haplotypes in African Americans from the Women's Health Initiative

scientific article

Germline Genetic Variants and Lung Cancer Survival in African Americans

scientific article published on 15 June 2017

Glutathione-S-transferase A3 knockout mice are sensitive to acute cytotoxic and genotoxic effects of aflatoxin B1

scientific journal article

Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations

scientific article

Hi-MC: a novel method for high-throughput mitochondrial haplogroup classification.

scientific article

High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE

scientific article

INTEGRATING COMMUNITY-LEVEL DATA RESOURCES FOR PRECISION MEDICINE RESEARCH.

scientific article published in January 2018

Identification of gene-gene and gene-environment interactions within the fibrinogen gene cluster for fibrinogen levels in three ethnically diverse populations

scientific article

Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science

scientific article

Identifying host genetic risk factors in the context of public health surveillance for invasive pneumococcal disease

scientific article

Identifying the genotype behind the phenotype: a role model found in VKORC1 and its association with warfarin dosing

scientific article

Imputation and quality control steps for combining multiple genome-wide datasets

scientific article

Imputation of coding variants in African Americans: better performance using data from the exome sequencing project

scientific article

Integrating host genomics with surveillance for invasive bacterial diseases

scientific article published on July 2008

Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies

scientific article

Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study

scientific article published in May 2013

KIDNEY DISEASE GENETICS AND THE IMPORTANCE OF DIVERSITY IN PRECISION MEDICINE.

scientific article

Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks

scientific article

LPA and PLG sequence variation and kringle IV-2 copy number in two populations

scientific article

Lack of associations of ten candidate coronary heart disease risk genetic variants and subclinical atherosclerosis in four US populations: the Population Architecture using Genomics and Epidemiology (PAGE) study

scientific article published on 13 March 2013

Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits

scientific article published on 28 July 2015

Lipid trait-associated genetic variation is associated with gallstone disease in the diverse Third National Health and Nutrition Examination Survey (NHANES III).

scientific article

Local ancestry transitions modify snp-trait associations

scientific article published in January 2018

Local genetic ancestry in CDKN2B-AS1 is associated with primary open-angle glaucoma in an African American cohort extracted from de-identified electronic health records

article

Maturation and application of phenome-wide association studies

scientific article published on 03 January 2022

Measures of exposure impact genetic association studies: an example in vitamin K levels and VKORC1.

scientific article

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

scientific article

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes

scientific article

Methods for optimizing statistical analyses in pharmacogenomics research

scientific article published on September 2009

Mind the gap: resources required to receive, process and interpret research-returned whole genome data

scientific article published on 03 June 2019

Mitochondrial variation and the risk of age-related macular degeneration across diverse populations

scientific article

Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project

scientific article published on 16 September 2020

Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study

scientific article

Mutations at the Ser50 residue of translation factor eIF-2alpha dominantly affect developmental rate, body weight, and viability of Drosophila melanogaster.

scientific article published in January 1997

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population

scientific article published on 08 October 2013

Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project.

scientific article published on 16 May 2012

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

scientific article published in Nature Communications

PRECISION MEDICINE: DATA AND DISCOVERY FOR IMPROVED HEALTH AND THERAPY.

scientific article

PRECISION MEDICINE: FROM DIPLOTYPES TO DISPARITIES TOWARDS IMPROVED HEALTH AND THERAPIES.

scientific article published in January 2018

Paternally transmitted FMR1 alleles are less stable than maternally transmitted alleles in the common and intermediate size range

scientific article published on 03 May 2002

Pattern of sequence variation across 213 environmental response genes

scientific article published on 13 September 2004

Peptide tyrosine tyrosine levels are increased in patients with urea cycle disorders.

scientific article published on 22 February 2012

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

scientific article

Phenome-Wide Association Studies: Embracing Complexity for Discovery

scientific article (publication date: 2015)

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

scientific article

Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network

scientific article

Pitfalls of merging GWAS data: lessons learned in the eMERGE network and quality control procedures to maintain high data quality

scientific article

Pleiotropic and sex-specific effects of cancer GWAS SNPs on melanoma risk in the population architecture using genomics and epidemiology (PAGE) study

scientific article

Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia

scientific article

Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia

scientific article published on 09 August 2013

Population Stratification in the Context of Diverse Epidemiologic Surveys Sans Genome-Wide Data

scientific article

Population differences in genetic risk for age-related macular degeneration and implications for genetic testing

scientific article published in January 2012

Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study

scientific article published on 28 June 2013

Precision Medicine: Improving health through high-resolution analysis of personal data

scientific article published on 01 January 2019

Predicting Incident Coronary Heart Disease Many Markers at a Time

scientific article published in December 2016

Predicting clopidogrel response using DNA samples linked to an electronic health record.

scientific article published on 21 December 2011

Predicting warfarin dosage in European-Americans and African-Americans using DNA samples linked to an electronic health record

scientific article

Prevalence of the fragile X syndrome in African-Americans

scientific article published in July 2002

Problems with genome-wide association studies

scientific article published on 01 June 2007

Quality control procedures for genome-wide association studies

scientific article published in 2011

Racial Disparities in Lung Cancer Survival: The Contribution of Stage, Treatment, and Ancestry

scientific article published on 06 June 2018

Rare variant APOC3 R19X is associated with cardio-protective profiles in a diverse population-based survey as part of the Epidemiologic Architecture for Genes Linked to Environment Study

scientific article

Reducing Clinical Noise for Body Mass Index Measures Due to Unit and Transcription Errors in the Electronic Health Record

scientific article

Replication and characterisation of genetic variants in the fibrinogen gene cluster with plasma fibrinogen levels and haematological traits in the Third National Health and Nutrition Examination Survey

scientific article

Replication of Associations with Electrocardio-graphic Traits in African Americans from Clinical and Epidemiologic Studies

article

Replication of associations between GWAS SNPs and melanoma risk in the Population Architecture Using Genomics and Epidemiology (PAGE) Study.

scientific article

Return of individual research results from genome-wide association studies: experience of the Electronic Medical Records and Genomics (eMERGE) Network

scientific article (publication date: April 2012)

Robust Replication of Genotype-Phenotype Associations across Multiple Diseases in an Electronic Medical Record

Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record

scientific article

SCN5A variation is associated with electrocardiographic traits in the Jackson Heart Study.

scientific article

Searching in the Dark: Phenotyping Diabetic Retinopathy in a De-Identified Electronic Medical Record Sample of African Americans

scientific article published on 20 July 2016

SecureMA: protecting participant privacy in genetic association meta-analysis

scientific article

Sequential sib-pair and association studies to detect genes in quantitative traits

scientific article published on 01 January 1997

Serum vitamins A and E as modifiers of lipid trait genetics in the National Health and Nutrition Examination Surveys as part of the Population Architecture using Genomics and Epidemiology (PAGE) study

scientific article

Shared Genetic Etiology of Autoimmune Diseases in Patients from a Biorepository Linked to De-identified Electronic Health Records

scientific article published on 20 October 2016

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms

scientific article published on 14 July 2016

Single nucleotide polymorphism discovery in TBX1 in individuals with and without 22q11.2 deletion syndrome.

scientific article

Somatic T-cell Receptor Diversity in a Chronic Kidney Disease PatientPopulation Linked to Electronic Health Records.

scientific article

Strategies for genotyping

scientific article published in January 2011

Surveillance for anthrax cases associated with contaminated letters, New Jersey, Delaware, and Pennsylvania, 2001.

scientific article published on October 2002

Synthesis-View: visualization and interpretation of SNP association results for multi-cohort, multi-phenotype data and meta-analysis

scientific article

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

scientific article

TESTING POPULATION-SPECIFIC QUANTITATIVE TRAIT ASSOCIATIONS FOR CLINICAL OUTCOME RELEVANCE IN A BIOREPOSITORY LINKED TO ELECTRONIC HEALTH RECORDS: LPA AND MYOCARDIAL INFARCTION IN AFRICAN AMERICANS.

scientific article

THE CHALLENGES IN USING ELECTRONIC HEALTH RECORDS FOR PHARMACOGENOMICS AND PRECISION MEDICINE RESEARCH

scientific article

The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study

scientific article

The detection and characterization of pleiotropy: discovery, progress, and promise

scientific article published on 28 July 2015

The effects of electronic medical record phenotyping details on genetic association studies: HDL-C as a case study

scientific article published on 6 May 2015

The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis

scientific article published in PLoS ONE

The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study

scientific article published on 8 January 2013

The patterns of natural variation in human genes

scientific article

Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry.

scientific article

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

scientific article

Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci

scientific article published on 8 April 2017

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained

scientific article

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

scientific article published in August 2017

Unravelling the human genome-phenome relationship using phenome-wide association studies.

scientific article published on 15 February 2016

Using Electronic Health Records To Generate Phenotypes For Research

scientific article published on 05 December 2018

Utilization of an EMR-biorepository to identify the genetic predictors of calcineurin-inhibitor toxicity in heart transplant recipients

scientific article published on January 2014

VKORC1 common variation and bone mineral density in the Third National Health and Nutrition Examination Survey

scientific article

Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies

scientific article

Variation in LPA is associated with Lp(a) levels in three populations from the Third National Health and Nutrition Examination Survey

scientific article

Visual integration of results from a large DNA biobank (BioVU) using synthesis-view

scientific article published on January 2011

Visually integrating and exploring high throughput Phenome-Wide Association Study (PheWAS) results using PheWAS-View

scientific article

Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups

scientific article

Willingness to Participate in a National Precision Medicine Cohort: Attitudes of Chronic Kidney Disease Patients at a Cleveland Public Hospital

scientific article published on 26 June 2018

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants

scientific article

eMERGEing progress in genomics-the first seven years

scientific article

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