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List of works by Diana C Spierings

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

scientific article published on 13 February 2020

Abstracts from the 3rd Conference on Aneuploidy and Cancer: Clinical and Experimental Aspects: Berkeley, CA, USA. 26 - 29 January 2017.

scientific article

Altering microtubule dynamics is synergistically toxic with spindle assembly checkpoint inhibition

scientific article published on 24 January 2020

Analysis of Released Circulating Tumor Cells During Surgery for Non-Small Cell Lung Cancer

scientific article published on 26 November 2019

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

scientific article published on 27 January 2021

BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes

scientific article published on 18 January 2018

Caspase-7 deficiency protects from endotoxin-induced lymphocyte apoptosis and improves survival.

scientific article published on 23 January 2009

Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice

scientific article published on 13 March 2019

Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals

scientific article

Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum

scientific article published in 2022

Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis

scientific article published in October 2005

Construction of Strand-seq libraries in open nanoliter arrays

publication published on 24 January 2022

Copy number alterations assessed at the single-cell level revealed mono- and polyclonal seeding patterns of distant metastasis in a small cell lung cancer patient.

scientific article

Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

scientific article

Detection of Circulating Tumor Cells in the Diagnostic Leukapheresis Product of Non-Small-Cell Lung Cancer Patients Comparing CellSearch® and ISET

scientific article published on 07 April 2020

Direct chromosome-length haplotyping by single-cell sequencing.

scientific article published on 19 September 2016

Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines ⬇️

scientific article published on October 1, 2010

Erratum to: Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.

scientific article published on 30 June 2016

Extensive Clonal Branching Shapes the Evolutionary History of High-Risk Pediatric Cancers

scientific article published on 10 February 2020

Genetic instability from a single S phase after whole-genome duplication

scientific article published on 30 March 2022

Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq

scientific article published on 12 December 2017

Interaction of tumour cells with cultured stromal cells from human bone marrow

scientific article published on 01 January 1994

InvertypeR: Bayesian inversion genotyping with Strand-seq data

scientific article published on 31 July 2021

Loss of drug-induced activation of the CD95 apoptotic pathway in a cisplatin-resistant testicular germ cell tumor cell line.

scientific article

Low p21Waf1/Cip1 protein level sensitizes testicular germ cell tumor cells to Fas-mediated apoptosis.

scientific article published on June 2004

Multi-platform discovery of haplotype-resolved structural variation in human genomes

Non-random Mis-segregation of Human Chromosomes.

scientific article published in June 2018

Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage

scientific article

Quantification of Aneuploidy in Mammalian Systems

scientific article published on 01 January 2019

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

scientific article (publication date: 2016)

Single-cell sequencing to quantify genomic integrity in cancer

scientific article published on 23 September 2017

Single-cell template strand sequencing by Strand-seq enables the characterization of individual homologs.

scientific article

Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons

scientific article published on 31 May 2016

Sperm DNA damage causes genomic instability in early embryonic development

scientific article published on 15 April 2020

TP53 loss initiates chromosomal instability in fallopian tube epithelial cells

scientific article published on 30 November 2021

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

scientific article published on 03 September 2018

The attractive Achilles heel of germ cell tumours: an inherent sensitivity to apoptosis-inducing stimuli.

scientific article

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α

scientific article published on 01 October 2018

Tissue distribution of the death ligand TRAIL and its receptors.

scientific article published in June 2004

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer

scientific article published on 27 May 2020

p53 Prohibits Propagation of Chromosome Segregation Errors that Produce Structural Aneuploidies

scientific article published in June 2017

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