Search filters

List of works by Kohsuke Tsuchiya

A human pathogenic bacterial infection model using the two-spotted cricket, Gryllus bimaculatus.

scientific article published on 3 July 2016

ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism

scientific article published on 05 July 2019

Caspase-1 initiates apoptosis in the absence of gasdermin D

scientific article published on 07 May 2019

Caspase-7 mediates caspase-1-induced apoptosis independently of Bid

scientific article published on 20 November 2019

Characterization of Innate and Adaptive Immune Responses in PYNOD-Deficient Mice

scientific article published on 30 April 2018

Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation

scientific article published on 14 January 2008

Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.

scientific article

Cutting edge: nitric oxide inhibits the NLRP3 inflammasome

scientific article published on 24 October 2012

Cytolysin-dependent escape of the bacterium from the phagosome is required but not sufficient for induction of the Th1 immune response against Listeria monocytogenes infection: distinct role of Listeriolysin O determined by cytolysin gene replacement

scientific article

Dependency of caspase-1 activation induced in macrophages by Listeria monocytogenes on cytolysin, listeriolysin O, after evasion from phagosome into the cytoplasm

scientific article published on 01 June 2008

Differences in gamma interferon production induced by listeriolysin O and ivanolysin O result in different levels of protective immunity in mice infected with Listeria monocytogenes and Listeria ivanovii

scientific article

Essential role of interleukin-12 (IL-12) and IL-18 for gamma interferon production induced by listeriolysin O in mouse spleen cells

scientific article

Expression of the Mycobacterium tuberculosis PPE37 protein in Mycobacterium smegmatis induces low tumour necrosis factor alpha and interleukin 6 production in murine macrophages

scientific article published on 13 January 2011

Inactivation of the MAPK signaling pathway by Listeria monocytogenes infection promotes trophoblast giant cell death

scientific article

Inflammasome-associated cell death: Pyroptosis, apoptosis, and physiological implications

scientific article published on 07 January 2020

Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes.

scientific article published on 21 June 2010

Involvement of caspase-9 in the inhibition of necrosis of RAW 264 cells infected with Mycobacterium tuberculosis.

scientific article published on 2 April 2007

Listeria monocytogenes Strain-Specific Impairment of the TetR Regulator Underlies the Drastic Increase in Cyclic di-AMP Secretion and Beta Interferon-Inducing Ability ⬇️

scientific article published on April 16, 2012

Listeriolysin O-induced membrane permeation mediates persistent interleukin-6 production in Caco-2 cells during Listeria monocytogenes infection in vitro.

scientific article published on July 2005

PD-1-PD-L1 pathway impairs T(h)1 immune response in the late stage of infection with Mycobacterium bovis bacillus Calmette-Guérin

article

Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity

scientific article published on 3 November 2013

Pneumolysin-Dependent Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Streptococcus pneumoniae.

scientific article published on 19 June 2017

Seeligeriolysin O, a protein toxin of Listeria seeligeri, stimulates macrophage cytokine production via Toll-like receptors in a profile different from that induced by other bacterial ligands.

scientific article published on 15 November 2005

Serum Syndecan-4 as a Possible Biomarker in Patients With Acute Pneumonia.

scientific article published on 20 April 2015

The RD1 locus in the Mycobacterium tuberculosis genome contributes to activation of caspase-1 via induction of potassium ion efflux in infected macrophages.

scientific article published on 13 July 2009

The RD1 locus in theMycobacterium tuberculosisgenome contributes to the maturation and secretion of IL-1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation ⬇️

scientific article published on August 23, 2013

The adaptor ASC exacerbates lethal Listeria monocytogenes infection by mediating IL-18 production in an inflammasome-dependent and -independent manner.

scientific article published on 22 October 2014

The inflammasome and its regulation

scientific article published on January 2014

Toll-like receptor 2- and MyD88-dependent phosphatidylinositol 3-kinase and Rac1 activation facilitates the phagocytosis of Listeria monocytogenes by murine macrophages.

scientific article

Type I interferon signaling regulates activation of the absent in melanoma 2 inflammasome during Streptococcus pneumoniae infection

scientific article

Vitamin B6 Prevents IL-1β Protein Production by Inhibiting NLRP3 Inflammasome Activation

scientific article published on 12 October 2016

Paulina is supported by:

About Paulina

Help