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List of works by Christoph Springfeld

A Tupaia paramyxovirus vector system for targeting and transgene expression

scientific article published on 15 August 2017

A ferret model of canine distemper virus virulence and immunosuppression.

scientific article published on December 2003

A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol.

scientific article

Advanced-stage pancreatic cancer: therapy options

scientific article published on 30 April 2013

An immunocompetent murine model for oncolysis with an armed and targeted measles virus.

scientific article published on 21 August 2007

An undifferentiated carcinoma at Klatskin-position with long-term complete remission after chemotherapy.

scientific article published on 24 April 2018

Anti-angiogenic activity of VXM01, an oral T-cell vaccine against VEGF receptor 2, in patients with advanced pancreatic cancer: A randomized, placebo-controlled, phase 1 trial.

scientific article published on 16 March 2015

Broadly neutralizing immune responses against hepatitis C virus induced by vectored measles viruses and a recombinant envelope protein booster

scientific article

Chemotherapy for advanced pancreatic adenocarcinoma in elderly patients (≥70 years of age): a retrospective cohort study at the National Center for Tumor Diseases Heidelberg.

scientific article published on 18 March 2014

Chemotherapy for pancreatic cancer

scientific article published on 15 March 2019

Chemovirotherapy for head and neck squamous cell carcinoma with EGFR-targeted and CD/UPRT-armed oncolytic measles virus.

scientific article

Durable remission under dual HER2 blockade with Trastuzumab and Pertuzumab in a patient with metastatic gallbladder cancer

scientific article published on 12 May 2016

Enhanced Control of Oncolytic Measles Virus Using MicroRNA Target Sites.

scientific article published on 12 April 2018

Envelope targeting: hemagglutinin attachment specificity rather than fusion protein cleavage-activation restricts Tupaia paramyxovirus tropism.

scientific article

Envelope-chimeric entry-targeted measles virus escapes neutralization and achieves oncolysis.

scientific article

Fatal varicella in an immunocompromised adult associated with a European genotype E2 variant of varicella zoster virus.

scientific article published on 3 December 2008

High prevalence of incidental and symptomatic venous thromboembolic events in patients with advanced pancreatic cancer under palliative chemotherapy: A retrospective cohort study

scientific article published on 22 April 2017

Identification and characterization of the Tupaia herpesvirus DNA polymerase gene.

scientific article published on December 1998

Liver cancers with stem/progenitor-cell features - a rare chemotherapy-sensitive malignancy

scientific article published on 5 June 2017

Locally Advanced Pancreatic Cancer: Neoadjuvant Therapy With Folfirinox Results in Resectability in 60% of the Patients

scientific article published on 28 June 2016

Mismatch repair deficiency is a rare but putative therapeutically relevant finding in non-liver fluke associated cholangiocarcinoma

scientific article published on 31 October 2018

NRG1 Fusions in KRAS Wild-type Pancreatic Cancer.

scientific article

Oncolytic efficacy and enhanced safety of measles virus activated by tumor-secreted matrix metalloproteinases.

scientific article published on August 2006

Palliative chemotherapy for pancreatic adenocarcinoma: a retrospective cohort analysis of efficacy and toxicity of the FOLFIRINOX regimen focusing on the older patient.

scientific article published on 6 December 2017

Pancreatic Cancer Surgery: The New R-status Counts

scientific article

Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response

scientific article published on 3 November 2017

Patients with Advanced Pancreatic Cancer and Hyperbilirubinaemia: Review and German Expert Opinion on Treatment with nab-Paclitaxel plus Gemcitabine

scientific article

Phase II Study of BGJ398 in Patients With FGFR-Altered Advanced Cholangiocarcinoma.

scientific article published on 28 November 2017

Poly(ADP-ribose) polymerase inhibition in pancreatic cancer

scientific article published on 20 December 2020

Prognostic Impact of Carboxylesterase 2 in Cholangiocarcinoma

scientific article published on 13 March 2019

Prognostic impact of lymph node involvement and the extent of lymphadenectomy (LAD) in adenocarcinoma of the esophagogastric junction (AEG)

scientific article published on 26 July 2013

Prognostic significance of microsatellite-instability in gastric and gastroesophageal junction cancer patients undergoing neoadjuvant chemotherapy

scientific article published on 04 January 2019

Programmed cell death ligand 1 (PD-L1, CD274) in cholangiocarcinoma - correlation with clinicopathological data and comparison of antibodies

scientific article published on 15 January 2019

Prostatic metastasis from intrahepatic cholangiocarcinoma

scientific article published on 18 July 2018

Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer.

scientific article published on 15 June 2017

Successful treatment with nab-paclitaxel and gemcitabine after FOLFIRINOX failure in a patient with metastasized pancreatic adenocarcinoma.

scientific article

Surgery in oesophago-gastric cancer with metastatic disease: Treatment, prognosis and preoperative patient selection.

scientific article published on 29 May 2015

Survival of Hepatocellular Carcinoma Patients Treated with Sorafenib beyond Progression

scientific article published on 11 April 2018

Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients

scientific article published on 01 April 2016

Tyrosine 110 in the measles virus phosphoprotein is required to block STAT1 phosphorylation.

scientific article published on 16 November 2006

VIROTHERAPY RESEARCH IN GERMANY - FROM ENGINEERING TO TRANSLATION A Review as contribution to the Combined Annual Meeting of the German and European Societies of Gene (and Cell) Therapy 2017.

scientific article published on 4 September 2017

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