Search filters

List of works by Robert Sebra

A Complete Genome Screening Program of Clinical Methicillin-Resistant Staphylococcus aureus Isolates Identifies the Origin and Progression of a Neonatal Intensive Care Unit Outbreak

scientific article published on 22 November 2019

A Novel Framework for Characterizing Genomic Haplotype Diversity in the Human Immunoglobulin Heavy Chain Locus

scientific article published on 23 September 2020

A hybrid approach for the automated finishing of bacterial genomes

scientific article

A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells

scientific article published on 22 December 2017

A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer

scientific article published on 22 May 2019

A physical and genetic map of identifies extensive rearrangement at the THC/CBD acid synthase locus

scientific article published on 08 November 2018

An integrated map of structural variation in 2,504 human genomes

scientific article

Analysis of the Aedes albopictus C6/36 genome provides insight into cell line utility for viral propagation

scientific article published on 10 January 2018

Application of Single-Cell Sequencing to Immunotherapy

scientific article published on 09 September 2020

Assembly and diploid architecture of an individual human genome via single-molecule technologies

scientific article published on 29 June 2015

Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege

scientific article published on 21 August 2020

Blurred Molecular Epidemiological Lines Between the Two Dominant Methicillin-Resistant Staphylococcus aureus Clones

scientific article published on 27 June 2019

COVID-19: Staging of a New Disease

scientific article published on 10 October 2020

Capturing pairwise and multi-way chromosomal conformations using chromosomal walks.

scientific article published on 30 November 2016

Cell-to-Cell Variation in Defective Virus Expression and Effects on Host Responses during Influenza Virus Infection

scientific article published on 14 January 2020

Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397

scientific article published on 6 April 2015

Chromosomal Integration of the Klebsiella pneumoniae Carbapenemase Gene, blaKPC, in Klebsiella Species Is Elusive but Not Rare

scientific article

Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution

scientific article (publication date: 30 January 2013)

Comparative genomic analysis of driver mutations in matched primary and recurrent meningiomas.

scientific article published on 28 May 2019

Complete Genome Sequence of KPC-Producing Klebsiella pneumoniae Strain CAV1193.

scientific article

Complete Sequencing of Plasmids Containing blaOXA-163 and blaOXA-48 in Escherichia coli Sequence Type 131.

scientific article published on 06 September 2016

Cytogenomic identification and long-read single molecule real-time (SMRT) sequencing of a Bardet-Biedl Syndrome 9 (BBS9) deletion

scientific article

Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children

scientific article published on 02 September 2020

DNA sequencing at ultra-high fidelity

scientific article published on 6 November 2017

Detection of endometrial precancer by a targeted gynecologic cancer liquid biopsy

Development and clinical application of an integrative genomic approach to personalized cancer therapy

scientific article published on June 2016

Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing

scientific article published on 01 April 2020

Don't overlook the little guy: An evaluation of the frequency of small plasmids co-conjugating with larger carbapenemase gene containing plasmids

scientific article published on 27 March 2019

Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

scientific article published on 01 November 2019

Emergence and Evolution of Multidrug-Resistant Klebsiella pneumoniae with both blaKPC and blaCTX-M Integrated in Chromosome

scientific article

Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae.

scientific article

Epigenetic preconditioning with decitabine sensitizes glioblastoma to temozolomide via induction of MLH1

scientific article published on 19 March 2020

Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis

scientific article published on 25 November 2019

Evolution and Transmission of Carbapenem-Resistant Klebsiella pneumoniae Expressing the blaOXA-232 Gene During an Institutional Outbreak Associated With Endoscopic Retrograde Cholangiopancreatography

scientific article published on April 2017

Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element

scientific article

Evolutionary History of the Global Emergence of the Escherichia coli Epidemic Clone ST131

scientific article published on 22 March 2016

Evolutionary history of the global emergence of the Escherichia coli epidemic clone ST131

scholarly article published 6 November 2015

Ex vivo human HSC expansion requires coordination of cellular reprogramming with mitochondrial remodeling and p53 activation

Extensive sequencing of seven human genomes to characterize benchmark reference materials

scientific article

Familial Hypercholesterolemia in a Healthy Elderly Population

scientific article published on 10 June 2020

First Report of blaIMP-14 on a Plasmid Harboring Multiple Drug Resistance Genes in Escherichia coli Sequence Type 131.

scientific article published on 31 May 2016

GENE-20. USE OF DECITABINE TO ALTER PATTERNS OF TREATMENT-INDUCED MUTAGENESIS IN GLIOBLASTOMA

scientific article published on 6 November 2017

Gaining comprehensive biological insight into the transcriptome by performing a broad-spectrum RNA-seq analysis

scientific article

Genetic associations with clozapine-induced myocarditis in patients with schizophrenia

scientific article published on 27 January 2020

Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review

scientific article published on 07 September 2019

Genome Plasticity of -Defective Staphylococcus aureus during Clinical Infection

scholarly article published by Deena R Altman in 2018

Genome Sequence of Bacterial Interference Strain Staphylococcus aureus 502A.

scientific article published on 10 April 2014

Genome-Wide Biases in the Rate and Molecular Spectrum of Spontaneous Mutations in Vibrio cholerae and Vibrio fischeri

scientific article published on 15 October 2016

Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study.

scientific article

Genomic confirmation of vancomycin-resistant Enterococcus transmission from deceased donor to liver transplant recipient

scientific article

Genomic epidemiology of complex, multi-species, plasmid-borne bla KPC carbapenemase in Enterobacterales in the UK, 2009-2014

scientific article published on 24 February 2020

Genomic epidemiology of global Klebsiella pneumoniae carbapenemase (KPC)-producing E. coli

Genomic profiling reveals mutational landscape in parathyroid carcinomas

scientific article

HIV-1 Infection of Primary CD4+ T Cells Regulates the Expression of Specific Human Endogenous Retrovirus HERV-K (HML-2) Elements

scientific article published on 18 October 2017

HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes

scientific article

High-coverage, long-read sequencing of Han Chinese trio reference samples.

scientific article

High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma

scientific article published on 01 August 2018

IMMU-60. MAPPING TUMORAL AND IMMUNE HETEROGENEITY IN PD-1 RESPONSIVE GLIOBLASTOMA

Identification of a novel RASD1 somatic mutation in a USP8-mutated corticotroph adenoma.

scientific article

In Reply: Retention of ATRX and DAXX Expression in Meningiomas

scientific article published on 01 February 2020

Influenza virus infection causes global RNAPII termination defects

Inhibition of the Nuclear Export Receptor XPO1 as a Therapeutic Target for Platinum-Resistant Ovarian Cancer

scientific article published on 20 September 2016

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis

scientific article published on 01 July 2020

Interpretable and context-free deconvolution of multi-scale whole transcriptomic data with UniCell deconvolve

scientific article published in 2023

Intrahost dynamics of antiviral resistance in influenza A virus reflect complex patterns of segment linkage, reassortment, and natural selection

scientific article published on 7 April 2015

Intratumoral heterogeneity and clonal evolution in liver cancer

scientific article published on 15 January 2020

Introductions and early spread of SARS-CoV-2 in the New York City area

scientific article published on 11 April 2020

Introductions and early spread of SARS-CoV-2 in the New York City area

scientific article published on 29 May 2020

Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae at a single institution: insights into endemicity from whole-genome sequencing

scientific article

Klebsiella quasipneumoniae Provides a Window into Carbapenemase Gene Transfer, Plasmid Rearrangements, and Patient Interactions with the Hospital Environment.

scientific article published on 24 May 2019

Limited Mitochondrial Activity Coupled With Strong Expression of CD34, CD90 and EPCR Determines the Functional Fitness of <i>ex vivo</i> Expanded Human Hematopoietic Stem Cells

scientific article published on 15 December 2020

Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.

scientific article

Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing

Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities

scientific article published on 03 May 2019

Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals

scientific article published on 01 July 2020

Metagenomic binning and association of plasmids with bacterial host genomes using DNA methylation.

scientific article

Methicillin-Susceptible, Vancomycin-Resistant Staphylococcus aureus, Brazil

scientific article

NF2 mutation status and tumor mutational burden correlate with immune cell infiltration in meningiomas

scientific article published on 13 July 2020

Negative feedback control of neuronal activity by microglia

scientific article published on 30 September 2020

Nested Russian Doll-Like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance Gene blaKPC

scientific article published on 11 April 2016

Nested Russian Doll-like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance GeneblaKPC

article

Neuronal impact of patient-specific aberrant NRXN1α splicing

scientific article published on 29 November 2019

ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms

scientific article published on 11 May 2020

Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany

scientific article

Parallel Epidemics of Community-Associated Methicillin-Resistant Staphylococcus aureus USA300 Infection in North and South America

scientific article published on 5 June 2015

PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks

scientific article published on 16 November 2020

Pathophysiology of SARS-CoV-2: targeting of endothelial cells renders a complex disease with thrombotic microangiopathy and aberrant immune response. The Mount Sinai COVID-19 autopsy experience

scientific article published on 22 May 2020

Peritumoral edema correlates with mutational burden in meningiomas

scientific article published on 12 August 2020

Personalized Circulating Tumor DNA Biomarkers Dynamically Predict Treatment Response and Survival In Gynecologic Cancers

scientific article published on 30 December 2015

Prevalence and disease predisposition of p.A91V perforin in an aged population of European ancestry

scientific article published on 01 February 2020

Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties

scientific article published on 19 April 2017

Quantifying influenza virus diversity and transmission in humans

scientific article

Quantitative and multiplexed DNA methylation analysis using long-read single-molecule real-time bisulfite sequencing (SMRT-BS).

scientific article

Real Time Investigation of a large Nosocomial Influenza A Outbreak Informed by Genomic Epidemiology

scientific article published on 15 May 2020

Real-Time Investigation of a Large Nosocomial Influenza A Outbreak Informed by Genomic Epidemiology

scientific article published on 30 November 2020

Real-time DNA sequencing from single polymerase molecules

scientific article

Recurrent IDH Mutations in High-Grade Meningioma

scientific article published on 17 March 2020

Resistance to Ceftazidime-Avibactam Is Due to Transposition of KPC in a Porin-Deficient Strain of Klebsiella pneumoniae with Increased Efflux Activity

scientific article published on 24 July 2017

SARS-CoV-2 Transmission among Marine Recruits during Quarantine

scientific article published on 11 November 2020

STK11 mutation status is associated with decreased survival in meningiomas

scientific article published on 07 April 2020

Sampling the host response to SARS-CoV-2 in hospitals under siege

scientific article published on 27 July 2020

Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant

scientific article

Single cell profiling of peanut-responsive T cells in peanut allergic subjects reveals heterogeneous effector Th2 subsets

scientific article published on 30 January 2018

Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes

scientific article published on 15 June 2015

Single-Molecule Real-Time (SMRT) Full-Length RNA-Sequencing Reveals Novel and Distinct mRNA Isoforms in Human Bone Marrow Cell Subpopulations.

scientific article published on 27 March 2019

The Complete Genome Sequence of the Emerging Pathogen Mycobacterium haemophilum Explains Its Unique Culture Requirements

scientific article

The Mce3R stress-resistance pathway is vulnerable to small-molecule targeting that improves tuberculosis drug activities

The Mce3R stress-resistance pathway is vulnerable to small-molecule targeting that improves tuberculosis drug activities

The PsychENCODE project

scientific article

The genetic basis of emerging vancomycin, linezolid, and daptomycin heteroresistance in a case of persistent Enterococcus faecium bacteremia

scientific article published on 16 January 2018

The genome of a subterrestrial nematode reveals adaptations to heat

scientific article published on 21 November 2019

Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models

scientific article published on 01 December 2020

Treatment-associated TP53 DNA-binding domain missense mutations in the pathogenesis of secondary gliosarcoma

scientific article published on 20 December 2017

Tumoral and immune heterogeneity in an anti-PD-1-responsive glioblastoma: a case study

scientific article published on 01 April 2020

USP8 and TP53 drivers are associated with CNV in a corticotroph adenoma cohort enriched for aggressive tumors

scientific article published on 21 November 2020

Use of Multiple Sequencing Technologies To Produce a High-Quality Genome of the Fungus Pseudogymnoascus destructans, the Causative Agent of Bat White-Nose Syndrome

scientific article published on 30 June 2016

Using single-cell multiple omics approaches to resolve tumor heterogeneity

scientific article published on 28 December 2017

Whole-genome sequencing identifies emergence of a quinolone resistance mutation in a case of Stenotrophomonas maltophilia bacteremia.

scientific article

Paulina is supported by:

About Paulina

Help