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List of works by Sunil Pancholi

A simple organ culture model for assessing the effects of growth factors on corneal re-epithelialization

scientific article published on 01 May 1996

ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942

scientific article published on 17 September 2019

AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo.

scientific article

Abiraterone shows alternate activity in models of endocrine resistant and sensitive disease

scientific article published on 11 July 2018

Amino acid depletion modulates vascular endothelial growth factor production during the life span of human vascular smooth muscle cells ⬇️

scientific article published on August 1, 1998

Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer

scientific article

Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer

scientific article published on 04 December 2019

Correction to: Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer

scientific article published on 31 January 2020

Detection of ESR1 Mutations in Single Circulating Tumor Cells on Estrogen Deprivation Therapy but Not in Primary Tumors from Metastatic Luminal Breast Cancer Patients

scientific article published on 24 October 2019

Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer

scientific article published on 10 July 2018

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

scientific article published on 30 November 2017

ESR1 is co-expressed with closely adjacent uncharacterised genes spanning a breast cancer susceptibility locus at 6q25.1

scientific article

Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor-Positive Breast Cancer

scientific article

Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo ⬇️

scientific article published on October 17, 2012

GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors

scientific article published on 06 May 2013

Identification of chemokine receptors as potential modulators of endocrine resistance in oestrogen receptor-positive breast cancers.

scientific article

PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance

scientific article published on 13 August 2020

Pattern of angiogenic cytokine release from human vascular smooth muscle cells programmed by amino acid deprivation

scientific article published on 01 September 2000

Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer.

scientific article

Src Is a Potential Therapeutic Target in Endocrine-Resistant Breast Cancer Exhibiting Low Estrogen Receptor-Mediated Transactivation

scientific article

Targeting the receptor tyrosine kinase RET sensitizes breast cancer cells to tamoxifen treatment and reveals a role for RET in endocrine resistance.

scientific article

Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer.

scientific article published on 8 June 2018

The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer

scientific article published on 01 October 2019

The anti-estrogen ICI 182,780, but not tamoxifen, inhibits the growth of MCF7 breast cancer cells refractory to long-term estrogen deprivation through downregulation of ER and IGF signalling

The anti-oestrogen ICI 182,780, but not tamoxifen, inhibits the growth of MCF-7 breast cancer cells refractory to long-term oestrogen deprivation through down-regulation of oestrogen receptor and IGF signalling.

scientific article published in December 2005

The effects of growth factors and conditioned media on the proliferation of human corneal epithelial cells and keratocytes

scientific article published on 01 January 1998

The interaction of the ER with ERBB2 and PI3K results in elevated levels of AKT and p90RSK in tamoxifen-resistant MCF-7 cells

scientific article published on 17 June 2005

Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities

scientific article published on 19 April 2020

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