List of works - Sovan Sarkar

A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.

scientific article

Amino acids and autophagy: cross-talk and co-operation to control cellular homeostasis.

scientific article published on 26 June 2014

Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

scientific article published on 21 June 2010

Autophagic clearance of aggregate-prone proteins associated with neurodegeneration.

scientific article

Autophagy researchers: Fu-Cheng Lin, Dalibor Mijaljica, Sovan Sarkar, Teresa Zoladek

scientific article published on 31 January 2014

Autophagy, lipophagy and lysosomal lipid storage disorders

scientific article

Chemical Screening Approaches Enabling Drug Discovery of Autophagy Modulators for Biomedical Applications in Human Diseases

scientific article published on 19 March 2019

Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases.

scientific article

Chemical screening platforms for autophagy drug discovery to identify therapeutic candidates for Huntington's disease and other neurodegenerative disorders.

scientific article

Clearance of mutant aggregate-prone proteins by autophagy.

scientific article

Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

scientific article

Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

scientific article published on 16 December 2020

Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.

scientific article

Direct Reprogramming of Fibroblasts into Embryonic Sertoli-like Cells by Defined Factors ⬇️

scientific article published on September 7, 2012

Direct lineage conversion of adult mouse liver cells and B lymphocytes to neural stem cells

scientific article

Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic kingdoms

scientific article

Dysregulation of autophagy as a common mechanism in lysosomal storage diseases.

scientific article published on 12 December 2017

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

scientific article published on 23 June 2013

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Hydrophilic protein associated with desiccation tolerance exhibits broad protein stabilization function

scholarly article

Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease

scientific article

In Vitro Screening Platforms for Identifying Autophagy Modulators in Mammalian Cells

scientific article published on 01 January 2019

In search of an "autophagomometer".

scientific article published on 23 July 2009

Inositol and IP3 levels regulate autophagy: biology and therapeutic speculations.

scientific article

Laforin, the most common protein mutated in Lafora disease, regulates autophagy

scientific article

Lithium induces autophagy by inhibiting inositol monophosphatase

scientific article

Lysosomal positioning coordinates cellular nutrient responses.

scientific article published on 13 March 2011

N-acetyl-serotonin offers neuroprotection through inhibiting mitochondrial death pathways and autophagic activation in experimental models of ischemic injury.

scientific article published on February 2014

PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder

scientific article published on 30 August 2016

Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.

scientific article

Regulation of mammalian autophagy in physiology and pathophysiology.

scientific article published on October 2010

Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle

scientific article published on 10 July 2017

Restarting stalled autophagy a potential therapeutic approach for the lipid storage disorder, Niemann-Pick type C1 disease.

scientific article published on June 2014

Selective Autophagy and Xenophagy in Infection and Disease

scientific article published on 13 November 2018

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

scientific article

The developmental potential of iPSCs is greatly influenced by reprogramming factor selection

scientific article

The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias

scientific article

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

scientific article

Wild-type PABPN1 is anti-apoptotic and reduces toxicity of the oculopharyngeal muscular dystrophy mutation.

scientific article published on 4 January 2008

List of works by Sovan Sarkar

A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.

Amino acids and autophagy: cross-talk and co-operation to control cellular homeostasis.

Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

Autophagic clearance of aggregate-prone proteins associated with neurodegeneration.

Autophagy researchers: Fu-Cheng Lin, Dalibor Mijaljica, Sovan Sarkar, Teresa Zoladek

Autophagy, lipophagy and lysosomal lipid storage disorders

Chemical Screening Approaches Enabling Drug Discovery of Autophagy Modulators for Biomedical Applications in Human Diseases

Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases.

Chemical screening platforms for autophagy drug discovery to identify therapeutic candidates for Huntington's disease and other neurodegenerative disorders.

Clearance of mutant aggregate-prone proteins by autophagy.

Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.

Direct Reprogramming of Fibroblasts into Embryonic Sertoli-like Cells by Defined Factors ⬇️

Direct lineage conversion of adult mouse liver cells and B lymphocytes to neural stem cells

Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic kingdoms

Dysregulation of autophagy as a common mechanism in lysosomal storage diseases.

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Hydrophilic protein associated with desiccation tolerance exhibits broad protein stabilization function

Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease

In Vitro Screening Platforms for Identifying Autophagy Modulators in Mammalian Cells

In search of an "autophagomometer".

Inositol and IP3 levels regulate autophagy: biology and therapeutic speculations.

Laforin, the most common protein mutated in Lafora disease, regulates autophagy

Lithium induces autophagy by inhibiting inositol monophosphatase

Lysosomal positioning coordinates cellular nutrient responses.

N-acetyl-serotonin offers neuroprotection through inhibiting mitochondrial death pathways and autophagic activation in experimental models of ischemic injury.

PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder

Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.

Regulation of mammalian autophagy in physiology and pathophysiology.

Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle

Restarting stalled autophagy a potential therapeutic approach for the lipid storage disorder, Niemann-Pick type C1 disease.

Selective Autophagy and Xenophagy in Infection and Disease

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

The developmental potential of iPSCs is greatly influenced by reprogramming factor selection

The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

Wild-type PABPN1 is anti-apoptotic and reduces toxicity of the oculopharyngeal muscular dystrophy mutation.