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List of works by Alastair Stewart

1-O-hexadecyl-2-acetyl-sn-glycero-3-phospho (N,N,N trimethyl) hexanolamine: an analogue of platelet-activating factor with partial agonist activity.

scientific article published in September 1991

2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition.

scientific article

2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer.

scientific article

A model of bridging angiogenesis in the rat.

scientific article

A randomized phase II trial of granulocyte-macrophage colony-stimulating factor therapy in severe sepsis with respiratory dysfunction.

scientific article published in July 2002

Airway remodelling in asthma: current understanding and implications for future therapies.

scientific article

Airway smooth muscle remodels pericellular collagen fibrils: implications for proliferation

scientific article published on 15 January 2010

Airway vascularity in asthma

scientific article published on 01 October 1999

Airway wall remodelling and hyperresponsiveness: modelling remodelling in vitro and in vivo.

scientific article

Airways smooth muscle: the next generation

scientific article published on 18 May 2009

Albumin inhibits platelet-activating factor (PAF)-induced responses in platelets and macrophages: implications for the biologically active form of PAF ⬇️

scientific article published on September 1, 1992

Altered activation of the L-arginine nitric oxide pathway during and after cardiopulmonary bypass.

scientific article published in November 1997

Annexin A1 influences in breast cancer: Controversies on contributions to tumour, host and immunoediting processes

scientific article published on 14 February 2017

Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.

scientific article

Antagonism of vasoconstriction induced by platelet-activating factor in guinea-pig perfused hearts by selective platelet-activating factor receptor antagonists

scientific article published on April 1987

Anti-remodelling drugs for the treatment of asthma: requirement for animal models of airway wall remodelling.

scientific article

Antigen-induced airway inflammation in the Brown Norway rat results in airway smooth muscle hyperplasia.

scientific article published in November 2002

Attenuation of antigen-induced bronchospasm by fenoterol in the guinea-pig ⬇️

scientific article published on January 1, 1984

Beta 2-adrenoceptor agonist-mediated inhibition of human airway smooth muscle cell proliferation: importance of the duration of beta 2-adrenoceptor stimulation.

scientific article

Beta2-adrenergic receptor agonists and cAMP arrest human cultured airway smooth muscle cells in the G(1) phase of the cell cycle: role of proteasome degradation of cyclin D1

scientific article published on 01 November 1999

Biased signalling from the glucocorticoid receptor: Renewed opportunity for tailoring glucocorticoid activity.

scientific article published on 17 February 2016

Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-β1.

scientific article

CD151, a laminin receptor showing increased expression in asthmatic patients, contributes to airway hyperresponsiveness through calcium signaling.

scientific article published on 27 April 2016

Can we differentiate between airway and vascular smooth muscle?

scientific article

Cardioprotective potential of annexin-A1 mimetics in myocardial infarction

scientific article

Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis

scientific article published on 10 July 2018

Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology

scientific article

Coal mine dust lung disease in the modern era.

scientific article published on 30 March 2017

Collagen impairs glucocorticoid actions in airway smooth muscle through integrin signalling.

scientific article published on 11 September 2006

Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group

scientific article published on 01 October 1999

Contribution of the p38MAPK signalling pathway to proliferation in human cultured airway smooth muscle cells is mitogen-specific.

scientific article published on 12 July 2004

Cool perfusion solutions for skin flaps: a new mixture of pharmacological agents which improves skin flap viability

scientific article published on 01 April 1995

Cortisol limits selected actions of synthetic glucocorticoids in the airway epithelium

scientific article published on 22 November 2017

Differential inhibition of thrombin- and EGF-stimulated human cultured airway smooth muscle proliferation by glucocorticoids.

scientific article published in January 2003

Do inflammatory mediators influence the contribution of airway smooth muscle contraction to airway hyperresponsiveness in asthma?

scientific article

Dual modes of action for disodium cromoglycate in inhibition of antigen-induced contractions of guinea-pig isolated airways smooth muscle.

scientific article

Effects of low dose intra-arterial monoclonal antibodies to ICAM-1 and CD11/CD18 on local and systemic consequences of ischaemia-reperfusion injury in skeletal muscle

scientific article published on 01 June 1996

Evidence for an intracellular action of platelet-activating factor in bovine cultured aortic endothelial cells

scientific article published on March 1989

Extracellular matrix, integrins, and mesenchymal cell function in the airways.

scientific article

Factors controlling airway smooth muscle proliferation in asthma.

scientific article published on March 2004

Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer.

scientific article published on 30 April 2018

Functional expression of IgG-Fc receptors in human airway smooth muscle cells.

scientific article

Glucocorticoid Insensitivity in Virally Infected Airway Epithelial Cells Is Dependent on Transforming Growth Factor-β Activity.

scientific article

Glucocorticoid resistance of migration and gene expression in a daughter MDA-MB-231 breast tumour cell line selected for high metastatic potential

scientific article published on 06 March 2017

Glucocorticoid-resistant asthma and novel anti-inflammatory drugs.

scientific article published on 31 May 2012

Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle

scientific article published on 01 July 1999

Heterogeneity in mechanisms influencing glucocorticoid sensitivity: the need for a systems biology approach to treatment of glucocorticoid-resistant inflammation.

scientific article

Human monocytes maintained in culture acquire functional responsiveness to platelet-activating factor that is independent of increases in protein tyrosine phosphorylation

scientific article published on 01 August 1997

Impact of extracellular matrix and strain on proliferation of bovine airway smooth muscle.

scientific article

Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival

scientific article

Inflammation: maladies, models, mechanisms and molecules

scientific article published on February 2016

Inhibition by salbutamol of the proliferation of human airway smooth muscle cells grown in culture

scientific article

Interaction of leukotriene D4 and histamine on bronchomotor tone, in the guinea-pig.

scientific article

Interleukin-1alpha and tumour necrosis factor-alpha modulate airway smooth muscle DNA synthesis by induction of cyclo-oxygenase-2: inhibition by dexamethasone and fluticasone propionate

scientific article

Involvement of capsaicin-sensitive afferent neurones in a vagal-dependent interaction between leukotriene D4 and histamine on bronchomotor tone ⬇️

scientific article published on December 1, 1984

Ischaemia-reperfusion injury in mouse skeletal muscle is reduced by N omega-nitro-L-arginine methyl ester and dexamethasone

scientific article published on 01 August 1997

Leukotriene D4 potentiates histamine-induced bronchoconstriction in guinea-pigs.

scientific article published on October 1984

Lipopolysaccharide-induced cell cycle arrest in macrophages occurs independently of nitric oxide synthase II induction.

scientific article published in May 2001

Localization of inducible nitric oxide synthase to mast cells during ischemia/reperfusion injury of skeletal muscle

scientific article published on 01 March 2000

Macrophage activation reduces mobilization of arachidonic acid by guinea-pig and rat peritoneal macrophages in vitro

scientific article published on 01 November 1990

Mitogenic actions of endothelin-1 and epidermal growth factor in cultured airway smooth muscle.

scientific article published in April 1994

Molecular and cellular targets in tissue remodelling

scientific article published on 01 January 2006

More muscle in asthma, but where did it come from?

scientific article published on 01 May 2012

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

scientific article published on 4 March 2016

Neutrophil-independent protective effect of r-metHuG-CSF in ischaemia-reperfusion injury in rat skeletal muscle

scientific article published on 01 February 2000

Nitric oxide synthase inhibitor, nitro-iminoethyl-L-ornithine, reduces ischemia-reperfusion injury in rabbit skeletal muscle

scientific article published on 01 January 1994

Nitric oxide synthase inhibitors improve skin flap survival in the rat

scientific article published on 01 January 1994

Nitric oxide synthase-independent generation of nitric oxide in rat skeletal muscle ischemia-reperfusion injury

scientific article published on 01 January 1999

Nitrite is produced by elicited but not by circulating neutrophils.

scientific article published on January 1993

Non-steroidal anti-inflammatory drugs, tumour immunity and immunotherapy ⬇️

scientific article published on February 21, 2012

On the terminology for describing the length-force relationship and its changes in airway smooth muscle

scientific article published in December 2004

On-chip surface acoustic wave and micropipette aspiration techniques to assess cell elastic properties

scientific article published on 01 January 2020

PPAR gamma ligands, 15-deoxy-delta12,14-prostaglandin J2 and rosiglitazone regulate human cultured airway smooth muscle proliferation through different mechanisms

scientific article

Plasminogen activation by airway smooth muscle is regulated by type I collagen

scientific article published on 06 August 2010

Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling.

scientific article published on December 2013

Plasminogen-stimulated inflammatory cytokine production by airway smooth muscle cells is regulated by annexin A2.

scientific article published in November 2013

Platelet serotonin release in rheumatoid arthritis: a study in food-intolerant patients

scientific article published on 01 August 1983

Platelet-activating factor and WEB-2086 directly modulate rat cardiomyocyte contractility

scientific article published on 01 February 1994

Platelet-activating factor biosynthesis in rat vascular smooth muscle cells

scientific article published on 01 May 1994

Platelet-activating factor may participate in signal transduction processes in rabbit leukocytes.

scientific article published on December 1991

Platelet-activating factor-induced vasoconstriction in rat isolated, perfused hearts: contribution of cyclo-oxygenase and lipoxygenase arachidonic acid metabolites

scientific article published on 01 August 1986

Potential for airway smooth muscle as therapeutic target is reflected in the breadth of expertise of next generation scientists

scientific article published on 24 October 2012

Prior heat stress improves survival of ischemic-reperfused skeletal muscle in vivo

scientific article published on 01 December 2000

Pro-inflammatory mediators increase levels of the noncoding RNA GAS5 in airway smooth muscle and epithelial cells

scientific article

Proliferative aspects of airway smooth muscle.

scientific article published in August 2004

Pulmonary therapeutics: rethinking the regimens and re-imagining the targets.

scientific article

Quantitative phase microscopy: a new tool for measurement of cell culture growth and confluency in situ.

scientific article published on 17 February 2004

R2D(2) for C(4)Eo: an 'alliance' of PGD(2) receptors is required for LTC(4) production by human eosinophils

scientific article published on April 2011

Refractive index measurement in viable cells using quantitative phase-amplitude microscopy and confocal microscopy

scientific article published on 01 May 2005

Regulation of human airway mesenchymal cell proliferation by glucocorticoids and beta2-adrenoceptor agonists.

scientific article published on 25 April 2005

Regulation of lung fibroblast activation by annexin A1.

scientific article

Resistance of fibrogenic responses to glucocorticoid and 2-methoxyestradiol in bleomycin-induced lung fibrosis in miceThis article is one of a selection of papers published in the Special Issue on Recent Advances in Asthma Research

scientific article published in July 2007

Resolvin D2 supports MCF-7 cell proliferation via activation of estrogen receptor

scientific article published on 30 July 2014

Safer approaches to therapeutic modulation of TGF-β signaling for respiratory disease

scientific article published on 17 February 2018

Salbutamol inhibits the proliferation of human airway smooth muscle cells grown in culture: relationship to elevated cAMP levels

scientific article published on 01 June 1995

Secreted factors from human mast cells trigger inflammatory cytokine production by human airway smooth muscle cells.

scientific article published on September 2012

Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice.

scientific article published on 07 February 2017

TGF-β: Master regulator of inflammation and fibrosis

scientific article published on 04 October 2018

Targeted Graphene Oxide Networks: Cytotoxicity and Synergy with Anticancer Agents

scientific article published on 07 December 2018

The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2-Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation.

scientific article

The antimalarial drug artesunate inhibits primary human cultured airway smooth muscle cell proliferation.

scientific article published on February 2014

The effect of glucocorticoids on proliferation of human cultured airway smooth muscle.

scientific article published on December 1995

The fibrogenic actions of lung fibroblast-derived urokinase: a potential drug target in IPF.

scientific article published on 31 January 2017

The influence of nitric oxide synthase 2 on cutaneous wound angiogenesis

scientific article published on 01 December 2011

The role of cellular adhesion molecules in surgery.

scientific article published on December 1995

The role of potassium channels in the inhibitory effects of beta 2-adrenoceptor agonists on DNA synthesis in human cultured airway smooth muscle.

scientific article published in January 1997

The survival of skeletal muscle myoblasts in vitro is sensitive to a donor of nitric oxide and superoxide, SIN-1, but not to nitric oxide or peroxynitrite alone.

scientific article published on August 1999

Thrombin-stimulated DNA synthesis in human cultured airway smooth muscle occurs independently of products of cyclo-oxygenase or 5-lipoxygenase.

scientific article

Timing of Administration of Dexamethasone or the Nitric Oxide Synthase Inhibitor, Nitro-l-Arginine Methyl Ester, is Critical for Effective Treatment of Ischaemia-Reperfusion Injury to Rat Skeletal Muscle ⬇️

scientific article published on August 1, 1997

Total synthesis of the endogenous inflammation resolving lipid resolvin D2 using a common lynchpin.

scientific article published on 3 December 2013

Transforming Growth Factor–β–Induced Differentiation of Airway Smooth Muscle Cells Is Inhibited by Fibroblast Growth Factor–2 ⬇️

scientific article published on December 13, 2012

Transforming growth factor-β impairs glucocorticoid activity in the A549 lung adenocarcinoma cell line.

scientific article

Translational Pharmacology

scientific article published on 19 January 2017

Tumor necrosis factor alpha modulates mitogenic responses of human cultured airway smooth muscle

article by Alastair Stewart et al published 1 January 1995 in American Journal of Respiratory Cell and Molecular Biology

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