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List of works by Lochlan Fennell

Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer

scientific article published on 11 January 2020

Copy number profiles of paired primary and metastatic colorectal cancers

scientific article published on 15 December 2017

DNA methylation changes that precede onset of dysplasia in advanced sessile serrated adenomas.

scientific article published on 14 June 2019

Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.

scientific article published on 17 April 2018

Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal Adenocarcinomas

scientific article published on 05 April 2019

MLH1-93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAFV600E mutation.

scientific article published on 5 January 2018

Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia.

scientific article published on 13 December 2017

RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers.

scientific article published on June 2017

The role of APC in WNT pathway activation in serrated neoplasia

scientific article published on 17 November 2017

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