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List of works by Sarah H Lockie

A new glucagon and GLP-1 co-agonist eliminates obesity in rodents

scientific article

A stereological analysis of NPY, POMC, Orexin, GFAP astrocyte, and Iba1 microglia cell number and volume in diet-induced obese male mice.

scientific article published on 5 March 2015

Activation of thermogenesis in brown adipose tissue and dysregulated lipid metabolism associated with cancer cachexia in mice.

scientific article published on 19 June 2012

Acyl ghrelin acts in the brain to control liver function and peripheral glucose homeostasis in male mice

scientific article published on 23 December 2014

AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning

scientific article published in February 2018

Anti-obesity effects of the combined administration of CB1 receptor antagonist rimonabant and melanin-concentrating hormone antagonist SNAP-94847 in diet-induced obese mice.

scientific article published on 3 April 2012

Brown adipose tissue thermogenesis in the resistance to and reversal of obesity: A potential new mechanism contributing to the metabolic benefits of proglucagon-derived peptides.

scientific article

CNS opioid signaling separates cannabinoid receptor 1-mediated effects on body weight and mood-related behavior in mice.

scientific article published on 2 August 2011

Carnitine acetyltransferase (Crat) in hunger-sensing AgRP neurons permits adaptation to calorie restriction

scientific article published on 22 June 2018

Carnitine acetyltransferase in Agrp neurons is required for the homeostatic adaptation to restricted feeding in male mice.

scientific article

Combination cannabinoid and opioid receptor antagonists improves metabolic outcomes in obese mice.

scientific article published on 7 September 2015

Des-Acyl Ghrelin and Ghrelin O-Acyltransferase Regulate Hypothalamic-Pituitary-Adrenal Axis Activation and Anxiety in Response to Acute Stress

scientific article published on 4 August 2016

Diet-induced obesity causes ghrelin resistance in reward processing tasks

scientific article published on 11 August 2015

Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling

scientific article

Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice

scientific article published on 17 April 2014

Food Seeking in a Risky Environment: A Method for Evaluating Risk and Reward Value in Food Seeking and Consumption in Mice

scientific article

Ghrelin-induced adiposity is independent of orexigenic effects

scientific article

Glucagon-like peptide-1 receptor in the brain: role in neuroendocrine control of energy metabolism and treatment target for obesity.

scientific article published on July 2013

Glucose Availability Predicts the Feeding Response to Ghrelin in Male Mice, an Effect Dependent on AMPK in AgRP Neurons

scientific article published on 01 November 2018

Glucose availability regulates ghrelin-induced food intake in the ventral tegmental area

scientific article published on 06 March 2019

Neonatal ghrelin programs development of hypothalamic feeding circuits

scientific article

Neural and humoral changes associated with the adjustable gastric band: insights from a rodent model ⬇️

scientific article published on March 27, 2012

The endocannabinoid system: role in glucose and energy metabolism

scientific article published on 14 April 2009

The hormonal signature of energy deficit: Increasing the value of food reward.

scientific article published on 19 August 2013

The temporal pattern of cfos activation in hypothalamic, cortical, and brainstem nuclei in response to fasting and refeeding in male mice.

scientific article published on 9 January 2014

Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans.

scientific article published in October 2013

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