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List of works by Lai-Xi Wang

4-Methylumbelliferyl glycosides of N-acetyl 4-thiochito-oligosaccharides as fluorogenic substrates for chitodextrinase from Vibrio furnissii ⬇️

scientific article published on 01 September 1997

A facile synthesis of a complex type N-glycan thiazoline as an effective inhibitor against the antibody-deactivating endo-β-N-acetylglucosaminidases

scientific article published on 07 December 2017

A two-step enzymatic glycosylation of polypeptides with complex N -glycans ⬇️

scientific article published on February 18, 2013

An Fc domain protein-small molecule conjugate as an enhanced immunomodulator

scientific article

Characterizing human α-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases

scientific article published on 01 October 2020

Chemoenzymatic Glycan Remodeling of Natural and Recombinant Glycoproteins

scientific article

Chemoenzymatic Methods for the Synthesis of Glycoproteins

scientific article published on 24 August 2018

Chemoenzymatic Synthesis and Receptor Binding of Mannose-6-Phosphate (M6P)-Containing Glycoprotein Ligands Reveal Unusual Structural Requirements for M6P Receptor Recognition

scientific article

Chemoenzymatic synthesis and lectin recognition of a selectively fluorinated glycoprotein ⬇️

scientific article published on March 21, 2013

Cholic acid as template for multivalent peptide assembly ⬇️

scientific article published on October 21, 2003

Conformational Heterogeneity of the HIV Envelope Glycan Shield

scientific article published on 30 June 2017

Convergent Synthesis of Homogeneous Glc1Man9GlcNAc2-Protein and Derivatives as Ligands of Molecular Chaperones in Protein Quality Control ⬇️

scientific article published on August 19, 2011

Designer α1,6-Fucosidase Mutants Enable Direct Core Fucosylation of Intact N-Glycopeptides and N-Glycoproteins.

scientific article published on 9 October 2017

Efficient glycosynthase mutant derived from Mucor hiemalis endo-beta-N-acetylglucosaminidase capable of transferring oligosaccharide from both sugar oxazoline and natural N-glycan

scientific article

Emerging Technologies for Making Glycan-Defined Glycoproteins ⬇️

scientific article published on December 14, 2011

FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies

scientific article published on 27 May 2020

Forces and dynamics of glucose and inhibitor binding to sodium glucose co-transporter SGLT1 studied by single molecule force spectroscopy

scientific article

Generation and Comparative Kinetic Analysis of New Glycosynthase Mutants from Streptococcus pyogenes Endoglycosidases for Antibody Glycoengineering

scientific article published on 22 August 2018

Glycan Remodeling of Human Erythropoietin (EPO) Through Combined Mammalian Cell Engineering and Chemoenzymatic Transglycosylation.

scientific article

Glycosylation-dependent opsonophagocytic activity of staphylococcal protein A antibodies

scientific article published on 27 August 2020

Glycosynthase Mutants of Endoglycosidase S2 Show Potent Transglycosylation Activity and Remarkably Relaxed Substrate Specificity for Antibody Glycosylation Remodeling

scientific article published on 10 June 2016

Human airway epithelia express catalytically active NEU3 sialidase

scientific article

Liquid-liquid diffusion crystallization improves the X-ray diffraction of EndoS, an endo-β-N-acetylglucosaminidase from Streptococcus pyogenes with activity on human IgG

scientific article

NEU1 Sialidase Expressed in Human Airway Epithelia Regulates Epidermal Growth Factor Receptor (EGFR) and MUC1 Protein Signaling ⬇️

scientific article published on January 13, 2012

Peracetylated laminaribiose: preparation by specific degradation of curdlan and its chemical conversion into N-acetylhyalobiuronic acid ⬇️

scientific article published on October 14, 1991

Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques

scientific article published in 2021

Realizing the promise of chemical glycobiology ⬇️

scientific article published on September 1, 2013

Revisiting the substrate specificity of mammalian α1,6-fucosyltransferase (FUT8) reveals that it catalyzes core fucosylation of N-glycans lacking α1,3-arm GlcNAc

scientific article

Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity

scientific article

Site-selective chemoenzymatic glycoengineering of Fab and Fc glycans of a therapeutic antibody

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins

scientific article

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

scientific article

Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S.

scientific article

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

scientific article

Synthesis of 1d-(1,3,5/2,4)-4-acetamido-5-amino-1,2,3-cyclohexanetriol and its incorporation into a pseudo-disaccharide ⬇️

scientific article published on September 15, 1995

Synthesis of aryl 3′-sulfo-β-lactosides as fluorogenic and chromogenic substrates for ceramide glycanases ⬇️

scientific article published on January 1, 1998

Synthetic HIV V3 Glycopeptide Immunogen Carrying a N334 N-Glycan Induces Glycan-Dependent Antibodies with Promiscuous Site Recognition

scientific article published on 08 November 2018

Synthetic carbohydrate antigens for HIV vaccine design

scientific article

Synthetic multivalent V3 glycopeptides display enhanced recognition by glycan-dependent HIV-1 broadly neutralizing antibodies

scientific article published on 3 May 2017

Systematic Synthesis and Binding Study of HIV V3 Glycopeptides Reveal the Fine Epitopes of Several Broadly Neutralizing Antibodies.

scientific article published on 17 April 2017

Targeting of the Purine Biosynthesis Host Cell Pathway Enhances the Activity of Tenofovir Against Sensitive and Drug-Resistant HIV-1 ⬇️

scientific article published on 06 August 2013

Top-Down Chemoenzymatic Approach to Synthesizing Diverse High-Mannose N-Glycans and Related Neoglycoproteins for Carbohydrate Microarray Analysis.

scientific article

Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE).

scientific article

α-KDOase Activity in Oyster and Synthesis of α- and β-4-Methylumbelliferyl Ketosides of 3-Deoxy-d-manno-octulosonic Acid (KDO) ⬇️

scientific article published on October 17, 1997

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