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List of works by James Rw Conway

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.

scientific article published in October 2017

Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.

scientific article published on 17 November 2015

Cell matrix adhesion in cell migration

scientific article published on 01 October 2019

Cholesterol regulates Syntaxin 6 trafficking at trans-Golgi network endosomal boundaries.

scientific article published on 17 April 2014

Combating pancreatic cancer with PI3K pathway inhibitors in the era of personalised medicine

scientific article published on 05 November 2018

Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors.

scientific article

Developments in preclinical cancer imaging: innovating the discovery of therapeutics.

scientific article published on 17 April 2014

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells

scientific article (publication date: December 2015)

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism.

scientific article published on 13 April 2018

IGFBP2 secretion by mammary adipocytes limits breast cancer invasion

scientific article published in 2023

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

scientific article published on 22 December 2015

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer.

scientific article

Kinase-Independent Functions of MASTL in Cancer: A New Perspective on MASTL Targeting

scientific article published on 06 July 2020

MASTL overexpression promotes chromosome instability and metastasis in breast cancer.

scientific article

Removing physiological motion from intravital and clinical functional imaging data

scientific article published on 09 July 2018

SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer.

scientific article published on 27 March 2017

The Inositol Polyphosphate 5-Phosphatase PIPP Regulates AKT1-Dependent Breast Cancer Growth and Metastasis

scientific article published on August 2015

The cross-talk of LDL-cholesterol with cell motility: insights from the Niemann Pick Type C1 mutation and altered integrin trafficking.

scientific article published on 14 September 2015

The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment

scientific article

The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking.

scientific article

Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment.

scientific article

Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology.

scientific article published on 4 December 2017

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

scientific article published in April 2017