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List of works by Derek N Woolfson

"Belt and braces": a peptide-based linker system of de novo design.

scientific article published in August 2003

A Modular Vaccine Platform Combining Self-Assembled Peptide Cages and Immunogenic Peptides

scientific article published on 11 January 2019

A basis set of de novo coiled-coil peptide oligomers for rational protein design and synthetic biology

scientific article

A de novo peptide hexamer with a mutable channel

scientific article

A designed system for assessing how sequence affects alpha to beta conformational transitions in proteins

scientific article published on 21 December 2001

A monodisperse transmembrane α-helical peptide barrel

scientific article published on 14 November 2016

A set of de novo designed parallel heterodimeric coiled coils with quantified dissociation constants in the micromolar to sub-nanomolar regime

scientific article published on 19 March 2013

Accessibility, reactivity, and selectivity of side chains within a channel of de novo peptide assembly

scientific article

Applying graph theory to protein structures: an atlas of coiled coils.

scientific article

Assembly pathway of a designed alpha-helical protein fiber.

scientific article

Assessing cellular response to functionalized α-helical peptide hydrogels.

scientific article published on 24 March 2014

Atypical bZIP domain of viral transcription factor contributes to stability of dimer formation and transcriptional function

scientific article published on 25 April 2007

Automated solid-phase concatenation of Aib residues to form long, water-soluble, helical peptides

scientific article published on 09 September 2020

Beyond icosahedral symmetry in packings of proteins in spherical shells

scientific article published on 8 August 2017

Bioinspired Silicification Reveals Structural Detail in Self-Assembled Peptide Cages. ⬇️

scientific article

Bioorthogonal dual functionalization of self-assembling peptide fibers

scientific article published on 24 February 2011

BrisSynBio: a BBSRC/EPSRC-funded Synthetic Biology Research Centre

scientific article

CCBuilder 2.0: Powerful and accessible coiled-coil modeling

scientific article published on 24 August 2017

CCBuilder: an interactive web-based tool for building, designing and assessing coiled-coil protein assemblies.

scientific article

Carbohydrate-Aromatic Interactions in Proteins

scientific article

Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability ⬇️

scientific article published on 13 March 2017

Coiled-Coil Design: Updated and Upgraded

scientific article published on January 2017

Computational design of water-soluble α-helical barrels

scientific article

Conformational Dynamics of Asparagine at Coiled-Coil Interfaces.

scientific article published on 22 November 2017

Constructing ion channels from water-soluble α-helical barrels

scientific article published on 10 May 2021

Construction and characterization of kilobasepair densely labeled peptide-DNA.

scientific article published on 7 October 2014

Construction of a Chassis for a Tripartite Protein-Based Molecular Motor.

scientific article published on 21 February 2017

Controlled microfluidic switching in arbitrary time-sequences with low drag

scientific article published on 8 May 2013

Controlling the Assembly of Coiled-Coil Peptide Nanotubes.

scientific article published on 14 December 2015

Correction to Modifying Self-Assembled Peptide Cages To Control Internalization into Mammalian Cells

scientific article published on 11 April 2019

Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design.

scientific article

De Novo-Designed α-Helical Barrels as Receptors for Small Molecules

scientific article published on 10 July 2018

De novo designed peptides for biological applications.

scientific article published on 04 March 2011

De novo protein design: how do we expand into the universe of possible protein structures?

scientific article

De novo targeting to the cytoplasmic and luminal side of bacterial microcompartments

scientific article published in Nature Communications

Decorating Self-Assembled Peptide Cages with Proteins.

scientific article published on 7 July 2017

Design and Construction of a One-Dimensional DNA Track for an Artificial Molecular Motor

Designed alpha-helical tectons for constructing multicomponent synthetic biological systems.

scientific article published in January 2009

Differential sensing with arrays of de novo designed peptide assemblies

scientific article published in 2023

Electrostatic control of thickness and stiffness in a designed protein fiber.

scientific article

Engineered and designed peptide-based fibrous biomaterials

Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm

scientific article published on 11 December 2017

Engineering nanoscale order into a designed protein fiber

scholarly article

Engineering protein stability with atomic precision in a monomeric miniprotein.

scientific article

Engineering the morphology of a self-assembling protein fibre

scientific article published on 01 May 2003

Erratum: Corrigendum: Local and macroscopic electrostatic interactions in single α-helices

article

Evaluation and deployment of isotype-specific salivary antibody assays for detecting previous SARS-CoV-2 infection in children and adults

scientific article published on 15 March 2023

Exploring sequence/folding space: folding studies on multiple hydrophobic core mutants of ubiquitin.

scientific article

Extended knobs-into-holes packing in classical and complex coiled-coil assemblies.

scientific article published in December 2003

Flow linear dichroism of some prototypical proteins.

scientific article published in September 2009

Functionalized α-Helical Peptide Hydrogels for Neural Tissue Engineering

scientific article published on 28 April 2015

Generalized Born Implicit Solvent Models Do Not Reproduce Secondary Structures of <i>De Novo</i> Designed Glu/Lys Peptides

scientific article published on 10 June 2022

Guiding Biomolecular Interactions in Cells Using de Novo Protein-Protein Interfaces

scientific article published on 14 May 2019

Hydra Mesoglea Proteome Identifies Thrombospondin as a Conserved Component Active in Head Organizer Restriction

scientific article published in Scientific Reports

ISAMBARD: an open-source computational environment for biomolecular analysis, modelling and design

scientific article

Installing hydrolytic activity into a completely de novo protein framework

scientific article

Interplay of hydrogen bonds and n→π* interactions in proteins

scientific article

Introducing branches into a self-assembling peptide fiber

scientific article published on 01 July 2003

Labile assembly of a tardigrade protein induces biostasis

scientific article published in 2024

Local and macroscopic electrostatic interactions in single α-helices.

scientific article published on 9 February 2015

MaP peptides: programming the self-assembly of peptide-based mesoscopic matrices

scientific article published on 01 September 2005

Maintaining and breaking symmetry in homomeric coiled-coil assemblies

scientific article published in Nature Communications

Membrane-spanning α-helical barrels as tractable protein-design targets.

scientific article published on August 2017

Metal binding to a zinc-finger peptide: a comparison between solution and the gas phase

scientific article published on 20 September 2010

Metallopolymer-Peptide Hybrid Materials: Synthesis and Self-Assembly of Functional, Polyferrocenylsilane-Tetrapeptide Conjugates

scientific article published on 19 January 2012

Microwave enhanced palladium catalysed coupling reactions: a diversity-oriented synthesis approach to functionalised flavones

scientific article published on 01 December 2006

Miniprotein Design: Past, Present, and Prospects.

scientific article

Modifying Self-Assembled Peptide Cages To Control Internalization into Mammalian Cells

scientific article published on 08 August 2018

Modular Design of Self-Assembling Peptide-Based Nanotubes

scientific article published on 28 July 2015

Modular design of peptide fibrillar nano- to microstructures

scientific article published on 01 September 2009

More than just bare scaffolds: towards multi-component and decorated fibrous biomaterials.

scientific article published on 02 August 2010

N@a and N@d: Oligomer and Partner Specification by Asparagine in Coiled-Coil Interfaces.

scientific article

Navigating the structural landscape of de novo α-helical bundles

scientific article published on 22 May 2019

New currency for old rope: from coiled-coil assemblies to α-helical barrels.

scientific article

On the satisfaction of backbone-carbonyl lone pairs of electrons in protein structures.

scientific article

Peptide Assembly Directed and Quantified Using Megadalton DNA Nanostructures

scientific article published on 08 August 2019

Peptide and protein based materials in 2010: from design and structure to function and application

scientific article published on 30 July 2010

Peptide and protein building blocks for synthetic biology: from programming biomolecules to self-organized biomolecular systems.

scientific article

Peptide-based fibrous biomaterials: Some things old, new and borrowed.

scientific article published on 9 October 2006

Polar assembly in a designed protein fiber

scientific article published on 01 December 2004

Polyelectrolyte–surfactant nanocomposite membranes formed at a liquid–liquid interface

article published in 2011

Predicting and Experimentally Validating Hot-Spot Residues at Protein-Protein Interfaces

scientific article published on 27 September 2019

Preferred side-chain constellations at antiparallel coiled-coil interfaces

scholarly article

Protein-small molecule interactions in neocarzinostatin, the prototypical enediyne chromoprotein antibiotic.

scientific article published in May 2007

Random-coil:α-helix equilibria as a reporter for the Lewis(X)-Lewis(X) interaction.

scientific article

Rational design and application of responsive alpha-helical peptide hydrogels

scientific article published on July 2009

Rational design of peptide-based building blocks for nanoscience and synthetic biology

scientific article

Robust De Novo-Designed Homotetrameric Coiled Coils

scientific article published on 09 March 2020

Self-assembled templates for polypeptide synthesis.

scientific article published on 20 October 2007

Self-assembling cages from coiled-coil peptide modules.

scientific article

Sequence and structural duality: designing peptides to adopt two stable conformations.

scientific article published in December 2004

Signatures of n→π* interactions in proteins.

scientific article

Socket: a program for identifying and analysing coiled-coil motifs within protein structures.

scientific article

Squaring the Circle in Peptide Assembly: From Fibers to Discrete Nanostructures by de Novo Design

scientific article published on 06 September 2012

Stabilizing and Understanding a Miniprotein by Rational Redesign

scientific article published on 08 July 2019

Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils.

scientific article published on 13 September 2012

Structural insights into quinolone antibiotic resistance mediated by pentapeptide repeat proteins: conserved surface loops direct the activity of a Qnr protein from a Gram-negative bacterium

scientific article

Structural resolution of switchable states of a de novo peptide assembly

scientific article published on 09 March 2021

Synthetic biology through biomolecular design and engineering.

scientific article

Synthetic ligands for apo-neocarzinostatin

scientific article published on 01 April 2006

Templating silica nanostructures on rationally designed self-assembled peptide fibers

scientific article published on 30 August 2008

The Tumbleweed: towards a synthetic proteinmotor.

scientific article published on 28 April 2009

The d'--d--d' vertical triad is less discriminating than the a'--a--a' vertical triad in the antiparallel coiled-coil dimer motif.

scientific article published on 31 January 2012

The dynamical interplay between a megadalton peptide nanocage and solutes probed by microsecond atomistic MD; implications for design

scientific article published on 01 December 2018

The non-covalent decoration of self-assembling protein fibers.

scientific article

Toward a Soluble Model System for the Amyloid State

scientific article published on 8 November 2017

Towards functional de novo designed proteins

scientific article published on 20 July 2019

Tuning the performance of an artificial protein motor

scientific article published on 21 September 2011

coiled-coil peptides as scaffolds for disrupting protein-protein interactions ⬇️

scientific article published on 07 August 2018

n-->pi* interactions in proteins

scientific article

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