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List of works by Elias Lolis

A Model of GAG/MIP-2/CXCR2 Interfaces and Its Functional Effects ⬇️

scientific article published on July 2, 2012

A Novel, Macrophage Migration Inhibitory Factor Suicide Substrate Inhibits Motility and Growth of Lung Cancer Cells

scientific article

A Plasmodium-encoded cytokine suppresses T-cell immunity during malaria

scientific article

A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity

scientific article published on 02 October 2019

A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice.

scientific article

Accessibility of selenomethionine proteins by total chemical synthesis: structural studies of human herpesvirus-8 MIP-II

scientific article published on 01 December 1998

Allosteric peptide regulators of chemokine receptors CXCR4 and CXCR7

scientific article published on 22 August 2013

An Analysis of MIF Structural Features that Control Functional Activation of CD74.

scientific article

An allosteric site on MKP5 reveals a strategy for small-molecule inhibition

scientific article published on 25 August 2020

CD74 is a novel transcription regulator

scientific article published on 28 December 2016

Characterization, Dynamics, and Mechanism of CXCR4 Antagonists on a Constitutively Active Mutant

scientific article published on 28 February 2019

Conformational dynamics of Ca2+-dependent responses in the polycystin-2 C-terminal tail.

scientific article published on 16 November 2015

Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor

scientific article

Crystal structure of chemically synthesized [N33A] stromal cell-derived factor 1α, a potent ligand for the HIV-1 “fusin” coreceptor ⬇️

scientific article published on June 9, 1998

Crystallographic and receptor binding characterization of Plasmodium falciparum macrophage migration inhibitory factor complexed to two potent inhibitors

scientific article published on 8 October 2014

Crystallographic studies of phosphonate-based alpha-reaction transition-state analogues complexed to tryptophan synthase

scientific article

Crystallography and site-directed mutagenesis of yeast triosephosphate isomerase: what can we learn about catalysis from a "simple" enzyme?

scientific article published on 01 January 1987

Development of chronic colitis is dependent on the cytokine MIF

scientific article published on 01 November 2001

Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition

scientific article

Direct link between cytokine activity and a catalytic site for macrophage migration inhibitory factor ⬇️

scientific article published on July 1, 1998

Expression, purification and crystallization of the novel Xenopus tropicalis ALDH16B1, a homologue of human ALDH16A1

scientific article published on 17 March 2019

Functional and receptor binding characterization of recombinant murine macrophage inflammatory protein 2: sequence analysis and mutagenesis identify receptor binding epitopes.

scientific article

Glucocorticoid counter regulation: macrophage migration inhibitory factor as a target for drug discovery

scientific article

Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family

scientific article

ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models

scientific article

Identification of allosteric peptide agonists of CXCR4.

scientific article

Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4.

scientific article published on 26 March 2018

Inhibition of MIF bioactivity by rational design of pharmacological inhibitors of MIF tautomerase activity.

scientific article published in June 2002

Inhibition of Paclitaxel-induced Decreases in Calcium Signaling ⬇️

scientific article published on September 17, 2012

Insights into Binding of Single-Stranded Viral RNA Template to the Replication-Transcription Complex of SARS-CoV-2 for the Priming Reaction from Molecular Dynamics Simulations

scientific article published on 24 February 2022

Interaction of MIF Family Proteins in Myocardial Ischemia/Reperfusion Damage and Their Influence on Clinical Outcome of Cardiac Surgery Patients

scientific article

MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations

scientific article

Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: EVIDENCE FOR PARTIAL ALLOSTERIC AGONISM IN COMPARISON WITH CXCL12 CHEMOKINE.

scientific article published on 19 May 2016

Macrophage migration inhibitory factor

Macrophage migration inhibitory factor interactions with glutathione and S-hexylglutathione.

scientific article published in June 1998

Macrophage migration inhibitory factor promotes intestinal tumorigenesis

scientific article

Macrophage migration inhibitory factor: a critical component of autoimmune inflammatory diseases.

scientific article

Modeling of both shared and distinct interactions between MIF and its homologue D-DT with their common receptor CD74.

scientific article published on 26 August 2016

Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.

scientific article published on 18 April 2018

Oligomerization of the polycystin-2 C-terminal tail and effects on its Ca2+-binding properties

scientific article

Orthologs of macrophage migration inhibitory factor from parasitic nematodes

scientific article published on 4 July 2008

PAK1 kinase is required for CXCL1-induced chemotaxis.

scientific article

Preliminary crystallographic analysis of murine macrophage inflammatory protein 2

scientific article published on 01 June 1992

Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity

scientific article

Protein crystallization facilitated by molecularly imprinted polymers ⬇️

scientific article published on June 20, 2011

Solution structure of murine macrophage inflammatory protein-2

scientific article

Structural Interactions Dictate the Kinetics of Macrophage Migration Inhibitory Factor Inhibition by Different Cancer-Preventive Isothiocyanates

scientific article

Structural Plasticity in the C-Terminal Region of Macrophage Migration Inhibitory Factor-2 Is Associated with an Induced Fit Mechanism for a Selective Inhibitor

scientific article published on 12 June 2018

Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1 ) Binding to Heparin

scientific article

Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating

scientific article

Tertiary structure of thiopurine methyltransferase from Pseudomonas syringae, a bacterial orthologue of a polymorphic, drug-metabolizing enzyme

scientific article

The D -dopachrome tautomerase ( DDT ) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF) ⬇️

scientific article published on August 4, 2011

The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity

scientific article published on 25 September 2020

The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents

scientific article

Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation

scientific article

When anti-CCR2 treatment for arthritis strikes out

scientific article published on 01 January 2011

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