List of works by David Capper

2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size

scientific article published on 2 November 2011

A 49-year old female with multiple extra-axial tumors

scientific article published in March 2017

A Phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma

scientific article published on 21 February 2016

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

scientific article

A single-arm phase II Austrian/German multicenter trial on continuous daily sunitinib in primary glioblastoma at first recurrence (SURGE 01-07).

scientific article

ACTH- and prolactin-producing pituitary gland microadenoma with biphasic features of atypia and intermediate filament expression

scientific article published in February 2006

ACTR-05. THE RANDOMIZED PHASE II ARTE TRIAL: BEVACIZUMAB PLUS HYPOFRACTIONATED RADIOTHERAPY VERSUS RADIOTHERAPY ALONE IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA.

scientific article published on 6 November 2017

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry

scientific article published on 6 October 2013

AT-10ATYPICAL TERATOID RHABDOID TUMORS AND POORLY DIFFERENTIATED CHORDOMAS: DISTINCT MOLECULAR ENTITIES WITH SMARCB1/INI1 LOSS AND DISMAL PROGNOSIS.

scientific article published on 30 May 2016

AT-11CRIBRIFORM NEUROEPITHELIAL TUMOR (CRINET): MOLECULAR CHARACTERIZATION OF A SMARCB1-DEFICIENT NON-RHABDOID TUMOR WITH FAVORABLE LONG-TERM OUTCOME.

scientific article published on 30 May 2016

ATNT-07FAVORABLE RESPONSE OF PATIENTS WITH GLIOBLASTOMA AT SECOND OR THIRD RECURRENCE TO REPEATED INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN COMBINATION WITH BEVACICUMAB.

scientific article published on 9 November 2015

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma

scientific article published on 27 November 2014

ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis

scientific article

Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups

Abstract LB-172: Novel candidate oncogenic drivers in pineoblastoma

Accurate calling of KIAA1549-BRAF fusions from DNA of human brain tumours using methylation array-based copy number and gene panel sequencing data

scientific article published on 17 December 2020

Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 19 December 2018

Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles

scientific article published on 29 February 2016

Addressing diffuse glioma as a systemic brain disease with single-cell analysis

scientific article published on 12 December 2011

Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities

scientific article published on 19 June 2015

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

scientific article published on 29 January 2011

Analysis of IDH mutation, 1p/19q deletion, and PTEN loss delineates prognosis in clinical low-grade diffuse gliomas

scientific article

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.

scientific article published on 21 March 2018

Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy

scientific article

Anti-tissue factor (TF9-10H10) treatment reduces tumor cell invasiveness in a novel migratory glioma model

scientific article published on 5 February 2013

Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes

scientific article published on August 2010

Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial

scientific article

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody

scientific article (publication date: July 2011)

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes

scientific article

BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum

scientific article

BRAF V600E analysis for the differentiation of papillary craniopharyngiomas and Rathke's cleft cysts.

scientific article published on 2 May 2015

BRAF V600E mutation is associated with mTOR signaling activation in glioneuronal tumors

scientific article published on 11 September 2013

BRAF V600E-specific immunohistochemistry reveals low mutation rates in biliary tract cancer and restriction to intrahepatic cholangiocarcinoma

scientific article published on 6 December 2013

BRAF-mutated pleomorphic xanthoastrocytoma is associated with temporal location, reticulin fiber deposition and CD34 expression.

scientific article

BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome

scientific article

BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis.

scientific article

Bevacizumab plus hypofractionated radiotherapy versus radiotherapy alone in elderly patients with glioblastoma: the randomized, open-label, phase II ARTE trial.

scientific article

Biomarker and Histopathology Evaluation of Patients with Recurrent Glioblastoma Treated with Galunisertib, Lomustine, or the Combination of Galunisertib and Lomustine

scientific article

Brain metastases of gastro-oesophageal cancer: evaluation of molecules with relevance for targeted therapies

scientific article published in March 2013

CASP9 germline mutation in a family with multiple brain tumors

scientific article

Challenges in the histopathological classification of ganglioglioma and DNT: microscopic agreement studies and a preliminary genotype-phenotype analysis

scientific article published on 09 December 2018

Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors

scientific article published on 27 October 2009

Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients

scientific article published in January 2015

Chromogenic in situ hybridization is a reliable alternative to fluorescence in situ hybridization for diagnostic testing of 1p and 19q loss in paraffin-embedded gliomas

scientific article

Classification of gliomas. Current progress and perspectives

scientific article published on 21 May 2015

Clinical neuropathology practice news 2-2012: BRAF V600E testing

scientific article published on March 2012

Coincidence of semilobar holoprosencephaly and Chiari II malformation: correlation of prenatal diagnostics and neuropathologic findings

scientific article published in May 2006

Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma.

scientific article published on 19 June 2009

Comparative integrated molecular analysis of intraocular medulloepitheliomas and central nervous system embryonal tumors with multilayered rosettes confirms that they are distinct nosologic entities

scientific article

Confirmation of R132H mutation of isocitrate dehydrogenase 1 as an independent prognostic factor in anaplastic astrocytoma

scientific article published on 8 October 2011

Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia

scientific article

Correction to: DNA methylation-based reclassification of olfactory neuroblastoma

scientific article published on 01 September 2018

Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1-deficient non-rhabdoid tumor with favorable long-term outcome

scientific article published on 6 July 2016

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas

scientific article published in 2021

DNA methylation profiling identifies two distinct subgroups in breast cancers with low hormone receptor expression, mainly associated with HER2 amplification status

scientific article published on 03 October 2021

DNA methylation profiling reliably distinguishes pulmonary enteric adenocarcinoma from metastatic colorectal cancer

scientific article published on 05 February 2019

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

scientific article published on 14 March 2017

DNA methylation-based classification of central nervous system tumours.

scientific article published on 14 March 2018

DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment

scientific article published on 01 November 2018

DNA methylation-based reclassification of olfactory neuroblastoma

scientific article published on 05 May 2018

Defective p53 antiangiogenic signaling in glioblastoma

scientific article

Desmoplastic Infantile Ganglioglioma/Astrocytoma (DIG/DIA) Are Distinct Entities with Frequent BRAFV600 Mutations

article

Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry

scientific article published on 16 August 2011

Detection of BRAF p.V600E Mutations in Melanoma by Immunohistochemistry Has a Good Interobserver Reproducibility

scientific article

Detection of isocitrate dehydrogenase 1 mutation R132H in myelodysplastic syndrome by mutation-specific antibody and direct sequencing

scientific article published on 12 March 2010

Detection of the BRAF V600E mutation in serous ovarian tumors: a comparative analysis of immunohistochemistry with a mutation-specific monoclonal antibody and allele-specific PCR.

scientific article published on 22 October 2012

Development, characterization, and reversal of acquired resistance to the MEK1 inhibitor selumetinib (AZD6244) in an in vivo model of childhood astrocytoma

scientific article

Diagnostics of Paediatric Supratentorial RELA Ependymomas: Integration of information from Histopathology, Genetics, DNA Methylation and Imaging

article

Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation

scientific article published in October 2013

Disseminating anaplastic brainstem oligodendroglioma associated with allelic loss in the tumor suppressor candidate region D19S246 of chromosome 19 mimicking an inflammatory central nervous system disease in a 9-year-old boy.

scientific article published in July 2005

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling

scientific article

Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma

scientific article published on 05 September 2018

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system

scientific article published on 24 October 2013

EGR-1 is regulated by N-methyl-D-aspartate-receptor stimulation and associated with patient survival in human high grade astrocytomas

scientific article

EMBR-01. MOLECULAR AND CLINICAL HETEROGENEITY IN HISTOLOGICALLY-DIAGNOSED CNS-PNET PATIENTS PROSPECTIVELY TREATED AS A SINGLE ENTITY: A REPORT FROM THE CHILDREN’S ONCOLOGY GROUP ACNS0332 TRIAL.

scientific article

EMBR-02. RECURRENT HOMOZYGOUS DELETION OF DROSHA AND MICRODUPLICATION OF PDE4DIP CONTAINING THE ANCESTRAL DUF1220 DOMAIN IN PINEOBLASTOMA

EMBR-15. DIAGNOSTIC RE-EVALUATION AND POOLED CLINICAL DATA ANALYSIS OF PATIENTS WITH PREVIOUS DIAGNOSIS OF CNS-PNET

EPEN-24. YAP1 FUSION PROTEINS MEDIATE ONCOGENIC ACTIVITY IN EPENDYMOMA VIA INTERACTION WITH TEAD TRANSCRIPTION FACTORS.

scientific article published on 22 June 2018

EPN-12PEDIATRIC SUPRATENTORIAL EPENDYMOMA: COMPARISON BETWEEN IMMUNOHISTOCHEMISTRY, FISH AND DNA METHYLATION ANALYSIS FOR RELA REARRANGEMENT AND HISTOLOGICAL CORRELATION.

scientific article published on 30 May 2016

EPN-30YAP1-MAMLD1 FUSIONS ALONE ARE SUFFICIENT TO FORM SUPRATENTORIAL EPENDYMOMA-LIKE TUMORS IN MICE.

scientific article published on 30 May 2016

EPND-13. YAP1-MAMLD1 FUSIONS ALONE ARE SUFFICIENT TO FORM SUPRATENTORIAL EPENDYMOMA-LIKE TUMORS IN MICE.

scientific article

Elevated HLA-E levels in human glioblastomas but not in grade I to III astrocytomas correlate with infiltrating CD8+ cells.

scientific article

Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.

scientific article

Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity

scientific article published on 7 January 2016

Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing

scientific article published on 17 December 2016

Evidence of H3 K27M mutations in posterior fossa ependymomas

scientific article

Expression pattern of the water channel aquaporin-4 in human gliomas is associated with blood-brain barrier disturbance but not with patient survival

scientific article published in May 2007

Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial

scientific article published on 17 October 2018

FGFR3 overexpression is a useful detection tool for FGFR3 fusions and sequence variations in glioma

scientific article published on 20 November 2020

Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma

scientific article published on 21 August 2014

Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter-hypermethylation - the NCT Neuro Master Match (N2M2) pilot study

scientific article published on 18 November 2017

GENE-13. PEDIATRIC MENINGIOMAS ARE CHARACTERIZED BY DISTINCT METHYLATION PROFILES DIFFERENT FROM ADULT MENINGIOMAS

scientific article published on 23 April 2019

GENO-20NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA.

scientific article

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.

scientific article published on 13 January 2014

Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas

scientific article published on 20 December 2016

Genetic Alterations in Gliosarcoma and Giant Cell Glioblastoma.

scientific article published on 7 October 2015

Genetic and epigenetic characterization of posterior pituitary tumors

scientific article published on 18 October 2021

Glial papillary tumour of the spinal cord with SMARCB1/INI1-loss and favourable long-term outcome

scientific article

Gliomatosis cerebri: no evidence for a separate brain tumor entity

scientific article published on 22 October 2015

H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers

scientific article published on 11 April 2017

HG-68COMBINED ALTERATIONS IN MAPK PATHWAY GENES, CDKN2A/B AND ATRX CHARACTERIZE ANAPLASTIC PILOCYTIC ASTROCYTOMA.

scientific article published on 30 May 2016

HGG-24. MOLECULAR, PATHOLOGICAL, RADIOLOGICAL AND IMMUNE PROFILING OF NON-BRAINSTEM PAEDIATRIC HIGH GRADE GLIOMA FROM THE HERBY PHASE II RANDOMISED TRIAL

scientific article published on 22 June 2018

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

scientific article published on 19 October 2015

Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases

scientific article

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.

scientific article published on 12 May 2015

IDH1 R132H mutation is a rare event in myeloproliferative neoplasms as determined by a mutation specific antibody

scientific article published on 9 June 2010

Immunohistochemical analysis of 1844 human epithelial and haematopoietic tumours and sarcomas for IDH1R132H mutation.

scientific article

Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma.

scientific article

Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases

scientific article

Immunohistochemistry is highly sensitive and specific for the detection of V600E BRAF mutation in melanoma.

scientific article

Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E.

scientific article published on 26 July 2013

Increased levels of 2-hydroxyglutarate in AML patients with IDH1-R132H and IDH2-R140Q mutations

scientific article published on November 2010

Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

scientific article published on 01 April 2020

Infratentorial IDH-mutant astrocytoma is a distinct subtype

scientific article published on 10 August 2020

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma

scientific article published on 10 July 2014

Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers

scientific article published on 10 March 2015

Integrated molecular characterization of IDH-mutant glioblastomas

scientific article published on 15 November 2018

Intramedullary Solitary Fibrous Tumor--A Benign Form of Hemangiopericytoma? Case Report and Review of the Literature

scientific article

Invited Review: DNA methylation-based classification of paediatric brain tumours

scientific article published on 19 January 2020

Isocitrate dehydrogenase 1 mutant R132H sensitizes glioma cells to BCNU-induced oxidative stress and cell death

scientific article published on November 2013

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course

scientific article published on 28 September 2019

LGG-11. REGULATION OF ONCOGENE-INDUCED SENESCENCE IN PILOCYTIC ASTROCYTOMA.

scientific article published on 22 June 2018

LGG-20. MOLECULARLY-DEFINED DIFFUSE LEPTOMENINGEAL GLIONEURONAL TUMOR (DLGNT) COMPRISES TWO SUBGROUPS WITH DISTINCT CLINICAL AND GENETIC FEATURES

LOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients

scientific article

Lack of BRAF V600E protein expression in primary central nervous system lymphoma

scientific article published in July 2013

Location-Dependent Patient Outcome and Recurrence Patterns in IDH1-Wildtype Glioblastoma

Low-grade epilepsy-associated neuroepithelial tumours - the 2016 WHO classification

scientific article published on 18 November 2016

MAP kinase activity supported by BRAF (V600E) mutation rather than gene amplification is associated with ETV1 expression in melanoma brain metastases

scientific article

MB-17NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA.

scientific article

MB-26SHH DESMOPLASTIC/NODULAR MEDULLOBLASTOMA AND GORLIN SYNDROME IN THE SETTING OF DOWN SYNDROME: CASE REPORT WITH MOLECULAR PROFILING.

scientific article published on 30 May 2016

MB-30OUTCOME OF CLINICAL “STANDARD RISK” MEDULLOBLASTOMA WITH CMYC AMPLIFICATION: A CASE REPORT AND ASSESSMENT OF THE LITERATURE.

scientific article published on 30 May 2016

MEDU-38. NEXT GENERATION MOLECULAR CHARACTERIZATION OF LOCALLY RECURRENT WNT PATHWAY MEDULLOBLASTOMA: A CASE REPORT.

scientific article published on 31 May 2017

MPTH-15MOLECULAR RECLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS INTO WELL-KNOWN AND NOVEL TUMOR ENTITIES.

scientific article

MRI Features of Histologically Diagnosed Supratentorial Primitive Neuroectodermal Tumors and Pineoblastomas in Correlation with Molecular Diagnoses and Outcomes: A Report from the Children's Oncology Group ACNS0332 Trial

scientific article published on 10 October 2019

Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases

scientific article published on 01 September 2019

Malignant Transformation of a Dysembryoplastic Neuroepithelial Tumor (DNET) Characterized by Genome-Wide Methylation Analysis

scientific article

Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective

scientific article published on 17 April 2013

Melanotic tumors of the nervous system are characterized by distinct mutational, chromosomal and epigenomic profiles

scientific article published on 15 December 2014

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein

scientific article published on 11 April 2013

Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups

scientific article published on 28 January 2016

Methylation-based classification of benign and malignant peripheral nerve sheath tumors

scientific article published on 8 February 2016

Modulation of TGF-beta activity by latent TGF-beta-binding protein 1 in human malignant glioma cells

scientific article

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

scientific article

Molecular Transition of an Adult Low-Grade Brain Tumor to an Atypical Teratoid/Rhabdoid Tumor Over a Time-Course of 14 Years

scientific article published on August 2017

Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain

scientific article published on May 2015

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial.

scientific article published in May 2018

Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features.

scientific article

Monoclonal antibody specific for IDH1 R132H mutation

scientific article

Multiple thromboembolic events in fetofetal transfusion syndrome in triplets contributing to the understanding of pathogenesis of hydranencephaly in combination with polymicrogyria

scientific article published on 25 September 2006

Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells

scientific article published on 24 February 2013

Mutation specific antibodies: tool or dinosaur?

scientific article published in September 2012

Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology.

scientific article

NEXT-GENERATION NEUROPATHOLOGY - IMPROVING DIAGNOSTIC ACCURACY FOR BRAIN TUMORS USING DNA METHYLATION ARRAY-BASED MOLECULAR PROFILING.

scientific article published in July 2014

NFM-11. PEDIATRIC MENINGIOMAS ARE MOLECULARLY DISTINCT FROM ADULT COUNTERPARTS

article published in 2018

Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms

scientific article published on 25 January 2014

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

scientific article

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study

scientific article published on 28 July 2016

Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets

scientific article published on 15 December 2015

No evidence for BRAF-V600E mutations in gastroeosophageal tumors: results from a high-throughput analysis of 534 cases using a mutation-specific antibody

scientific article published in October 2013

No prognostic value of IDH1 mutations in a series of 100 WHO grade II astrocytomas

scientific article published on 19 April 2012

Novel, improved grading system(s) for IDH-mutant astrocytic gliomas.

scientific article published on 23 April 2018

Nuclear relocation of STAT6 reliably predicts NAB2-STAT6 fusion for the diagnosis of solitary fibrous tumour

scientific article

PCR- and restriction endonuclease-based detection of IDH1 mutations

scientific article published on 18 August 2009

PDCT-05. MOLECULAR DIAGNOSTICS REVEAL 60% HIGHER SURVIVAL FOR MOLECULARLY-VERIFIED VERSUS HISTOPATHOLOGICALLY-DIAGNOSED PEDIATRIC SUPRATENTORIAL CENTRAL NERVOUS SYSTEM EMBRYONAL TUMORS AND PINEOBLASTOMAS; A REPORT FROM THE CHILDREN’S ONCOLOGY GROUP

PDTM-38. PEDIATRIC MENINGIOMAS ARE CHARACTERIZED BY DISTINCT METHYLATION PROFILES DIFFERENT FROM ADULT MENINGIOMAS

PDTM-47. CHARACTERIZATION OF THE SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE IN PILOCYTIC ASTROCYTOMA AND ITS ROLE IN ONCOGENE-INDUCED SENESCENCE

PNR-21FOUR NEW BRAIN TUMOR ENTITIES EMERGE FROM MOLECULAR CLASSIFICATION OF CNS PNETs

scientific article published on 30 May 2016

PNR-33MOLECULAR RE-EVALUATION OF INSTITUTIONALLY DIAGNOSED CNS-PNETS: CLINICAL CONSEQUENCES OF CONFINED DIAGNOSTIC GROUPS.

scientific article published on 30 May 2016

PROGNOSTIC AND PREDICTIVE BIOMARKER-BASED SUBGROUPS IN THE NOA-04 TRIAL.

scientific article published in July 2014

Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo

scientific article published on 25 January 2017

Papillary Tumor of the Pineal Region: A Distinct Molecular Entity

scientific article

Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA

scientific article published on 13 February 2019

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

scientific article

Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors.

scientific article published on 7 October 2015

Pediatric atypical choroid plexus papilloma reconsidered: increased mitotic activity is prognostic only in older children

Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma.

scientific article

Pitfalls in the assessment of MGMT expression and in its correlation with survival in diffuse astrocytomas: proposal of a feasible immunohistochemical approach.

scientific article

Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis.

scientific article published on 11 April 2016

Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience.

scientific article

Preoperative assessment of haemostasis in patients undergoing stereotactic brain biopsy.

scientific article

Primary glioblastoma cultures: can profiling of stem cell markers predict radiotherapy sensitivity?

scientific article published on 18 July 2014

Printed peptide arrays identify prognostic TNC serumantibodies in glioblastoma patients

scientific article

Prognostic value of the extent of resection in supratentorial WHO grade II astrocytomas stratified for IDH1 mutation status: a single-center volumetric analysis

scientific article published on 25 June 2016

Proximity ligation assay evaluates IDH1R132H presentation in gliomas

scientific article

Radiogenomics of Glioblastoma: Machine Learning-based Classification of Molecular Characteristics by Using Multiparametric and Multiregional MR Imaging Features

scientific article

Radiomic subtyping improves disease stratification beyond key molecular, clinical and standard imaging characteristics in patients with glioblastoma

scientific article published on 28 September 2017

Rathke's cleft cyst rupture as potential initial event of a secondary perifocal lymphocytic hypophysitis: proposal of an unusual pathogenetic event and review of the literature

scientific article

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

scientific article published on 05 August 2021

Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma

scientific article published in Nature Communications

Response to trametinib treatment in progressive pediatric low-grade glioma patients

scientific article published on 07 October 2020

Risk factors for glioblastoma therapy associated complications

scientific article

Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1

scientific article published on 27 June 2019

SHH desmoplastic/nodular medulloblastoma and Gorlin syndrome in the setting of Down syndrome: case report, molecular profiling, and review of the literature

scientific article

Sarcoma classification by DNA methylation profiling

scientific article published on 21 January 2021

Satisfying your neuro-oncologist: a fast approach to routine molecular glioma diagnostics

scientific article published on 01 November 2018

Secondary hematoma expansion in intracerebral hemorrhage during rivaroxaban therapy.

scientific article published on 3 February 2014

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations

scientific article

Sellar Region Atypical Teratoid/Rhabdoid Tumors (ATRT) in Adults Display DNA Methylation Profiles of the ATRT-MYC Subgroup

scientific article published on 10 January 2018

Severe hypoxia and multiple infarctions resembling Creutzfeldt-Jakob disease.

scientific article published in January 2008

Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.

scientific article

Spatial transcriptome analysis reveals Notch pathway-associated prognostic markers in IDH1 wild-type glioblastoma involving the subventricular zone

scientific article

Spinal metastasis of gliosarcoma: array-based comparative genomic hybridization for confirmation of metastatic spread

scientific article published on 22 July 2014

Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation

scientific article published on 12 February 2009

Survival according to BRAF-V600 tumor mutations--an analysis of 437 patients with primary melanoma

scientific article published on 24 January 2014

Synchronous pituitary adenoma and pituicytoma.

scientific article published on 16 September 2015

TERT Promoter Mutations and Risk of Recurrence in Meningioma

scientific article published on 13 December 2015

TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma

scientific article published on 23 March 2021

Tall cell papillary thyroid carcinoma: new diagnostic criteria and mutations in BRAF and TERT.

scientific article published on 13 April 2015

Targeting the BRAF V600E mutation in multiple myeloma

scientific article

Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

scientific article published on 26 September 2016

The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

scientific article published on 07 December 2018

The case for DNA methylation based molecular profiling to improve diagnostic accuracy for central nervous system embryonal tumors (not otherwise specified) in adults

scientific article published on 6 October 2017

The embryonic stem cell factor UTF1 serves as a reliable diagnostic marker for germinomas

scientific article

The evolution of the anaplastic cerebellar liponeurocytoma: case report and review of the literature

scientific article published on January 2015

The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling.

scientific article published on 25 February 2018

The whole-genome landscape of medulloblastoma subtypes

scientific article published in July 2017

Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities

scientific article published on 28 October 2019

Tumour necrosis factor receptor superfamily member 9 (TNFRSF9) is up-regulated in reactive astrocytes in human gliomas

scientific article published in February 2015

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

scientific article published on 25 June 2009

VE1 immunohistochemistry in pituitary adenomas is not associated with BRAF V600E mutation

scientific article published on 16 April 2013

Validation of a Manual Protocol for BRAF V600E Mutation-specific Immunohistochemistry.

scientific article published in May 2015

Voxel-wise radiogenomic mapping of tumor location with key molecular alterations in patients with glioma

scientific article published on 01 October 2018

WHO 2016 Classification of gliomas

scientific article published on 16 August 2017

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

scientific article published on 02 September 2019

cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification

scientific article published on 20 December 2016

cIMPACT-NOW update 1: Not Otherwise Specified (NOS) and Not Elsewhere Classified (NEC).

scientific article

cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant.

scientific article published in March 2018

p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer.

scientific article published in June 2016

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