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List of works by Mark S Moehle

Abrogation of α-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats

scientific article

Activation of the mGlu1 metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M4 muscarinic receptor allosteric modulators

scientific article published on 16 August 2018

Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice.

scientific article

Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M4 Muscarinic Receptor.

scientific article published in December 2017

Co-Activation of Metabotropic Glutamate Receptor 3 and Beta-Adrenergic Receptors Modulates Cyclic-AMP, Long-Term Potentiation, and Disrupts Memory Reconsolidation

scientific article

Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents

scientific article

LRRK2 inhibition attenuates microglial inflammatory responses

scientific article

LRRK2 secretion in exosomes is regulated by 14-3-3.

scientific article published on 25 July 2013

Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration

scientific article published on 15 June 2015

Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury.

scientific article published on 22 April 2015

M1 and M2 immune activation in Parkinson's Disease: Foe and ally?

scientific article

Roles of the M4 acetylcholine receptor in the basal ganglia and the treatment of movement disorders

scientific article published on 18 June 2019

T227. THE METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1 REGULATES STRIATAL DOPAMINE RELEASE VIA AN ENDOCANNABINOID-DEPENDENT MECHANISM: IMPLICATIONS FOR THE TREATMENT OF SCHIZOPHRENIA.

scientific article published in April 2018

The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.

scientific article published on 29 April 2015

Unique functional and structural properties of the LRRK2 protein ATP-binding pocket

scientific article

Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.

scientific article published on 10 February 2016

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