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List of works by Raimund J. Ober

3D RESOLUTION MEASURE FOR MULTIFOCAL PLANE MICROSCOPY.

scientific article

3D single molecule tracking and superresolution microscopy using multifocal plane microscopy

scientific article published on December 2012

3D single molecule tracking of quantum-dot labeled antibody molecules using multifocal plane microscopy

scientific article

3D single molecule tracking with multifocal plane microscopy reveals rapid intercellular transferrin transport at epithelial cell barriers

scientific article

A 3D Resolution Measure for Optical Microscopy

scientific article

A comparative study of high resolution microscopy imaging modalities using a three-dimensional resolution measure.

scientific article

A resolution measure for three-dimensional microscopy.

scientific article

A software framework for the analysis of complex microscopy image data.

scientific article

A state space based approach to localizing single molecules from multi-emitter images.

scientific article published in January 2017

A stochastic analysis of distance estimation approaches in single molecule microscopy - quantifying the resolution limits of photon-limited imaging systems.

scientific article published in September 2013

A two-stage method for automated detection of ring-like endosomes in fluorescent microscopy images

scientific article published on 27 June 2019

Achievable accuracy of parameter estimation for multidimensional NMR experiments.

scientific article published in July 2002

An information-theoretic approach to designing the plane spacing for multifocal plane microscopy.

scientific article published on February 2015

Analyses of TCR clustering at the T cell-antigen-presenting cell interface and its impact on the activation of naive CD4+ T cells

scientific article published on 27 September 2006

Analyses of the recycling receptor, FcRn, in live cells reveal novel pathways for lysosomal delivery.

scientific article

Analysis of Point Based Image Registration Errors With Applications in Single Molecule Microscopy.

scientific article published on December 2013

Analysis of exponential data using a noniterative technique: application to surface plasmon experiments.

scientific article

Antibody targeting of HER2/HER3 signaling overcomes heregulin-induced resistance to PI3K inhibition in prostate cancer

scientific article

Antigen dynamics govern the induction of CD4(+) T cell tolerance during autoimmunity.

scientific article published on 25 May 2016

Autoantibody depletion ameliorates disease in murine experimental autoimmune encephalomyelitis

scientific article published on 19 June 2013

Automatic Endosomal Structure Detection And Localization in Fluorescence Microscopic Images.

scientific article

Beyond Rayleigh's criterion: a resolution measure with application to single-molecule microscopy.

scientific article

Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.

scientific article published on January 2009

Commentary: "There's been a Flaw in Our Thinking".

scientific article published on 16 July 2015

Comparison of estimation algorithms in single-molecule localization.

scientific article published on February 2010

Compensation for loss of ligand activity in surface plasmon resonance experiments.

scientific article published in July 2002

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

scholarly article

Conferring the binding properties of the mouse MHC class I-related receptor, FcRn, onto the human ortholog by sequential rounds of site-directed mutagenesis

scientific article published on 16 December 2004

Cramér-Rao Lower Bound for Point Based Image Registration With Heteroscedastic Error Model for Application in Single Molecule Microscopy.

scientific article

Designing the focal plane spacing for multifocal plane microscopy

scientific article

Determination of localization accuracy based on experimentally acquired image sets: applications to single molecule microscopy.

scientific article published on March 2015

Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies

scholarly article

Dual objective fluorescence microscopy for single molecule imaging applications

scientific article

Effect of Time Discretization on the Limit of the Accuracy of Parameter Estimation for Moving Single Molecules Imaged by Fluorescence Microscopy

scientific article published on May 2012

Effect of time discretization of the imaging process on the accuracy of trajectory estimation in fluorescence microscopy

scientific article

Elucidation of intracellular recycling pathways leading to exocytosis of the Fc receptor, FcRn, by using multifocal plane microscopy

scientific article

Engineered clearing agents for the selective depletion of antigen-specific antibodies

scientific article

Engineering a HER2-specific antibody-drug conjugate to increase lysosomal delivery and therapeutic efficacy

scientific article published on 01 April 2019

Engineering multivalent antibodies to target heregulin-induced HER3 signaling in breast cancer cells

scientific article published on 26 December 2013

Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels

scientific article published on 25 September 2005

Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans

scientific article published on 01 February 2003

Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level

scientific article

FISHER INFORMATION FOR EMCCD IMAGING WITH APPLICATION TO SINGLE MOLECULE MICROSCOPY

scientific article

FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions

scientific article published on January 2014

Fisher information matrix for branching processes with application to electron-multiplying charge-coupled devices

scientific article

Fisher information theory for parameter estimation in single molecule microscopy: tutorial

scientific article published on July 2016

Fluorescent Microspheres as Point Sources: A Localization Study.

scientific article published on 28 July 2015

From sorting endosomes to exocytosis: association of Rab4 and Rab11 GTPases with the Fc receptor, FcRn, during recycling.

scientific article

Generation of mutated variants of the human form of the MHC class I-related receptor, FcRn, with increased affinity for mouse immunoglobulin G.

scientific article published in September 2003

Hepatic function of FcRn revealed: Implications for overcoming drug-mediated hepatotoxicity.

scientific article

High accuracy 3D quantum dot tracking with multifocal plane microscopy for the study of fast intracellular dynamics in live cells

scientific article

How Accurately Can a Single Molecule be Localized when Imaged Through an Optical Microscope?

scientific article

How accurately can a single molecule be localized in three dimensions using a fluorescence microscope?

scientific article

IMAGE REGISTRATION ERROR ANALYSIS WITH APPLICATIONS IN SINGLE MOLECULE MICROSCOPY.

scientific article published on May 2012

Improved single particle localization accuracy with dual objective multifocal plane microscopy.

scientific article

Increasing the serum persistence of an IgG fragment by random mutagenesis.

scientific article published on July 1997

Influence of Prior Knowledge on the Accuracy Limit of Parameter Estimation in Single-Molecule Fluorescence Microscopy.

scientific article published in May 2013

Intensity-based axial localization approaches for multifocal plane microscopy.

scientific article

Investigating the usage of point spread functions in point source and microsphere localization.

scientific article published on February 2016

Investigation of the numerics of point spread function integration in single molecule localization

scientific article published in June 2015

Limit of the Accuracy of Parameter Estimation for Moving Single Molecules Imaged by Fluorescence Microscopy.

scientific article published on January 2011

Limit of the Accuracy of Parameter Estimation for Two Molecules Moving in Close Proximity.

scientific article published on May 2015

Localization accuracy in single molecule microscopy using electron-multiplying charge-coupled device cameras.

scientific article published on March 2012

Localization accuracy in single-molecule microscopy

scientific article

Localizing single molecules in three dimensions - a brief review

scientific article

Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption

scientific article published on 10 December 2016

Macrophage-Mediated Trogocytosis Leads to Death of Antibody-Opsonized Tumor Cells

scientific article published on 25 May 2016

Measurement Errors in Fluorescence Microscopy Image Registration ⬇️

scientific article published on November 2012

Microscope calibration protocol for single-molecule microscopy

scientific article published on 01 January 2021

Myelin oligodendrocyte glycoprotein-specific antibodies from multiple sclerosis patients exacerbate disease in a humanized mouse model.

scientific article

Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans

scientific article published on 24 July 2018

Neonatal Fc receptor blockade by Fc engineering ameliorates arthritis in a murine model

scientific article

Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis

scientific article published on 30 April 2019

New results on the single molecule localization problem in two and three dimensions

scientific article published on August 2015

Noise suppression of point spread functions and its influence on deconvolution of three-dimensional fluorescence microscopy image sets.

scientific article

Phagocytosis of antibody-opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages.

scientific article published on 13 February 2018

Publisher Correction: Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software

scientific article published on 01 June 2019

Quantitative Aspects of Single Molecule Microscopy

scientific article published in January 2015

Quantitative study of single molecule location estimation techniques

scientific article

Remote focusing multifocal plane microscopy for the imaging of 3D single molecule dynamics with cellular context

scientific article published on January 2017

Resolution limit of image analysis algorithms

scientific article published in Nature Communications

Selective depletion of antigen-specific antibodies for the treatment of demyelinating disease

scientific article published on 16 November 2020

Simultaneous imaging of different focal planes in fluorescence microscopy for the study of cellular dynamics in three dimensions.

scientific article

State space approach to single molecule localization in fluorescence microscopy.

scientific article

Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software

scientific article published on 08 April 2019

Targeting FcRn for the modulation of antibody dynamics

scientific article

Targeting FcRn for therapy: from live cell imaging to in vivo studies in mice.

scientific article

Targeting FcRn to Generate Antibody-Based Therapeutics

scientific article published on 22 August 2018

Targeting Phosphatidylserine with Calcium-Dependent Protein-Drug Conjugates for the Treatment of Cancer

scientific article published on 22 September 2017

Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.

scientific article published on December 2008

The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans

scientific article (publication date: August 2001)

The central residues of a T cell receptor sequence motif are key determinants of autoantigen recognition in murine experimental autoimmune encephalomyelitis.

scientific article published in January 2005

The choice of reference cell in the analysis of kinetic data using BIAcore.

scientific article

The effect of pH dependence of antibody-antigen interactions on subcellular trafficking dynamics

scientific article

The encephalitogenic, human myelin oligodendrocyte glycoprotein-induced antibody repertoire is directed toward multiple epitopes in C57BL/6-immunized mice.

scientific article published in July 2013

The influence of signal noise on the accuracy of kinetic constants measured by surface plasmon resonance experiments

scientific article published on 01 August 1999

The level of HER2 expression is a predictor of antibody-HER2 trafficking behavior in cancer cells

scientific article published on January 2014

Two approximations for the geometric model of signal amplification in an electron-multiplying charge-coupled device detector.

scientific article

Ultrahigh accuracy imaging modality for super-localization microscopy.

scientific article

Use of Fc-Engineered Antibodies as Clearing Agents to Increase Contrast During PET.

scientific article

Using multifocal plane microscopy to reveal novel trafficking processes in the recycling pathway

scientific article

Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn.

scientific article

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