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List of works by Karl Ekwall

'Arc' escorts siRNAs in heterochromatin assembly

scientific article published on 01 March 2007

A DNA microarray for fission yeast: minimal changes in global gene expression after temperature shift.

scientific article published in January 2004

A NASP (N1/N2)-related protein, Sim3, binds CENP-A and is required for its deposition at fission yeast centromeres.

scientific article

A chromatin-remodeling protein is a component of fission yeast mediator

scientific article published on 9 July 2010

A genome-wide role for CHD remodelling factors and Nap1 in nucleosome disassembly

scientific article published on 17 May 2007

A new member of the Sin3 family of corepressors is essential for cell viability and required for retroelement propagation in fission yeast

scientific article

A new role for the transcriptional corepressor SIN3; regulation of centromeres.

scientific article published in January 2003

A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe.

scientific article published on 18 August 2004

A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin.

scientific article

A promoter-level mammalian expression atlas

scientific article

A second Wpl1 anti-cohesion pathway requires dephosphorylation of fission yeast kleisin Rad21 by PP4.

scientific article published on 24 April 2017

A snapshot of Snf2 enzymes in fission yeast.

scientific article published on December 2013

ABCE1 is a highly conserved RNA silencing suppressor

scientific article published on 6 February 2015

AML Displays Increased CTCF Occupancy Associated to Aberrant Gene Expression and Transcription Factor Binding

scientific article published on 31 March 2020

Abo1 is required for the H3K9me2 to H3K9me3 transition in heterochromatin

scientific article published on 08 April 2020

Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity

scientific article

An inventory of the P-type ATPases in the fission yeast Schizosaccharomyces pombe

scientific article published on 18 April 2003

Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA

scientific article

Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation

scientific article published on 26 March 2014

Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation

scientific article published on 12 September 2013

CHD1 remodelers regulate nucleosome spacing in vitro and align nucleosomal arrays over gene coding regions in S. pombe.

scientific article

CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression.

scientific article published on 17 February 2017

Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia

scientific article published on 21 December 2016

Cell-cycle regulation of cohesin stability along fission yeast chromosomes

scientific article

Centromere domain organization and histone modifications.

scientific article

Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity

scientific article published on 16 February 2014

Chd1 remodelers maintain open chromatin and regulate the epigenetics of differentiation.

scientific article published on 06 March 2010

Chromatin immunoprecipitation using microarrays

scientific article published in January 2009

Chromatin remodeler Fft3 plays a dual role at blocked DNA replication forks

scientific article published on 01 October 2019

Comparative functional genomics of the fission yeasts

scientific article

Comprehensive mapping of the effects of azacitidine on DNA methylation, repressive/permissive histone marks and gene expression in primary cells from patients with MDS and MDS-related disease

scientific article

Comprehensive profiling of the fission yeast transcription start site activity during stress and media response

scientific article published on 01 February 2019

Copy number of 8q24.3 drives HSF1 expression and patient outcome in cancer: an individual patient data meta-analysis

scientific article published on 07 November 2019

Correction: Telomeric Repeats Facilitate CENP-ACnp1Incorporation via Telomere Binding Proteins

scientific article published in PLoS ONE

DNA topoisomerase III localizes to centromeres and affects centromeric CENP-A levels in fission yeast.

scientific article

Dicer is required for chromosome segregation and gene silencing in fission yeast cells.

scientific article

Distinct centromere domain structures with separate functions demonstrated in live fission yeast cells

scientific article published on 19 August 2003

Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe

scientific article published on July 2015

Epigenetic activation and inactivation of centromeres

scientific article published on 01 January 2014

Epigenetic control of centromere behavior

scientific article published on January 2007

Epigenetics, chromatin and genome organization: recent advances from the ENCODE project

scientific article

Epigenetics: heterochromatin meets RNAi.

scientific article published on March 2009

Ethyl Methanesulfonate Mutagenesis in Schizosaccharomyces pombe

scientific article published on 01 August 2017

FANTOM5 CAGE profiles of human and mouse samples

scientific article published on 29 August 2017

Factors that promote H3 chromatin integrity during transcription prevent promiscuous deposition of CENP-A(Cnp1) in fission yeast

scientific article

Fission yeast Iec1-ino80-mediated nucleosome eviction regulates nucleotide and phosphate metabolism

scientific article published on 23 November 2009

Fission yeast hrp1, a chromodomain ATPase, is required for proper chromosome segregation and its overexpression interferes with chromatin condensation

scientific article

Functional Divergence between Histone Deacetylases in Fission Yeast by Distinct Cellular Localization and In Vivo Specificity.

scientific article published in July 2002

Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity

scientific article published on April 2002

Genetic Analysis of Schizosaccharomyces pombe

scientific article published on 01 August 2017

Genetic characterisation of hda1+, a putative fission yeast histone deacetylase gene

scientific article published on July 1998

Genome-wide analysis of HDAC function

scientific article

Genome-wide mapping of histone modifications and mass spectrometry reveal H4 acetylation bias and H3K36 methylation at gene promoters in fission yeast

scientific article published on June 2010

Genome-wide mapping of nucleosome positions in Schizosaccharomyces pombe.

scientific article published on 20 February 2009

Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions

scientific article published on April 2006

Genome-wide patterns of histone modifications in fission yeast

scientific article published on 01 January 2006

Genome-wide studies of histone demethylation catalysed by the fission yeast homologues of mammalian LSD1

scientific article published on 18 April 2007

Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast

scientific article

H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly

scientific article published on 29 August 2019

HAT-HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress

scientific article published on 24 July 2009

Heterochromatin tells CENP-A where to go.

scientific article published on June 2008

High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence

scientific article published on 27 November 2020

High-throughput transcription profiling identifies putative epigenetic regulators of hematopoiesis.

scientific article published on 26 March 2014

Histone H2B Ubiquitylation Regulates Histone Gene Expression by Suppressing Antisense Transcription in Fission Yeast

scientific article published on 25 July 2019

Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes

scientific article published on 20 August 2021

Histone modification patterns and epigenetic codes.

scientific article published on 08 January 2009

Hrp3, a chromodomain helicase/ATPase DNA binding protein, is required for heterochromatin silencing in fission yeast

scientific article published on 01 July 2002

Identification of noncoding transcripts from within CENP-A chromatin at fission yeast centromeres.

scientific article

Individual subunits of the Ssn6-Tup11/12 corepressor are selectively required for repression of different target genes.

scientific article published on 13 November 2006

Interaction of Epe1 with the heterochromatin assembly pathway in Schizosaccharomyces pombe

scientific article published on April 2007

Leo1 is essential for the dynamic regulation of heterochromatin and gene expression during cellular quiescence

scientific article published on 17 July 2019

Mating-Type Determination in Schizosaccharomyces pombe

scientific article published on 01 August 2017

Mediator Promotes CENP-A Incorporation at Fission Yeast Centromeres.

scientific article published in December 2012

Mediator promotes CENP-a incorporation at fission yeast centromeres.

scientific article

Molecular biology. The paradox of silent heterochromatin

scientific article published on 01 May 2008

Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation.

scientific article

Mutations in histone modulators are associated with prolonged survival during azacitidine therapy

scientific article published on 03 March 2016

Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function

scientific article published on 01 November 1996

New insights into how chromatin remodellers direct CENP-A to centromeres.

scientific article published on May 2011

Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing

scientific article

Physical mapping of the Schizosaccharomyces pombe histone genes.

scientific article published on November 1994

Podbat: a novel genomic tool reveals Swr1-independent H2A.Z incorporation at gene coding sequences through epigenetic meta-analysis

scientific article

Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks

scientific article published on 29 September 2011

RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing

scientific article

RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription

retracted paper

RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe

scientific article published on 23 January 2014

Regulating retrotransposon activity through the use of alternative transcription start sites

scientific article published on 22 February 2016

Repression of Cell Differentiation by a cis-Acting lincRNA in Fission Yeast.

scientific article published on 18 January 2018

Repression of a mating type cassette in the fission yeast by four DNA elements

scientific article published on 01 October 1991

Restoration of KMT2C/MLL3 in human colorectal cancer cells reinforces genome-wide H3K4me1 profiles and influences cell growth and gene expression

scientific article published on 29 May 2020

Retraction: RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription

scientific article published on 01 October 2005

Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae

scientific article published on 31 January 2010

Selecting Schizosaccharomyces pombe Diploids

scientific article published on 05 July 2017

Setting up Schizosaccharomyces pombe Crosses/Matings

scientific article published on 05 July 2017

Similar mechanisms drive centromeric silencing and gene repression

scientific article published on 01 March 2003

Sin3: a flexible regulator of global gene expression and genome stability.

scientific article

Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing

scientific article published on 19 April 2007

Splicing factors facilitate RNAi-directed silencing in fission yeast

scientific article

Spore Analysis and Tetrad Dissection of Schizosaccharomyces pombe

scientific article published on 05 July 2017

Telomeric repeats facilitate CENP-A(Cnp1) incorporation via telomere binding proteins

scientific article

The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes

scientific article published on 02 January 2020

The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres

scientific article

The FUN30 chromatin remodeler, Fft3, protects centromeric and subtelomeric domains from euchromatin formation

scientific article

The Fun30 chromatin remodeler Fft3 controls nuclear organization and chromatin structure of insulators and subtelomeres in fission yeast.

scientific article published on 23 March 2015

The NAM8 gene in Saccharomyces cerevisiae encodes a protein with putative RNA binding motifs and acts as a suppressor of mitochondrial splicing deficiencies when overexpressed.

scientific article published in May 1992

The Paf1 complex factors Leo1 and Paf1 promote local histone turnover to modulate chromatin states in fission yeast

scientific article published on 29 October 2015

The RITS complex-A direct link between small RNA and heterochromatin.

scientific article published on February 2004

The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains

scientific article published on 13 November 2009

The binding of Chp2's chromodomain to methylated H3K9 is essential for Chp2's role in heterochromatin assembly in fission yeast

scientific article published in PLoS ONE

The chromatin-remodeling factor FACT contributes to centromeric heterochromatin independently of RNAi.

scientific article

The chromodomain protein Swi6: a key component at fission yeast centromeres.

scientific article

The endoplasmic reticulum cation P-type ATPase Cta4p is required for control of cell shape and microtubule dynamics.

scientific article published on 10 June 2002

The inner nuclear membrane proteins Man1 and Ima1 link to two different types of chromatin at the nuclear periphery in S. pombe

scientific article

The role of MutY homolog (Myh1) in controlling the histone deacetylase Hst4 in the fission yeast Schizosaccharomyces pombe

scientific article

The roles of SNF2/SWI2 nucleosome remodeling enzymes in blood cell differentiation and leukemia

scientific article published on 19 February 2015

The roles of histone modifications and small RNA in centromere function.

scientific article published in January 2004

The silent P mating type locus in fission yeast contains two autonomously replicating sequences

scientific article published on February 1993

Topoisomerase I regulates open chromatin and controls gene expression in vivo

scientific article published on 4 June 2010

Topoisomerases, chromatin and transcription termination.

scientific article published on March 2011

Topokaryotyping demonstrates single cell variability and stress dependent variations in nuclear envelope associated domains

scientific article published on 01 December 2018

Trans-acting factors and properly positioned DNA elements repress mating-type genes in fission yeast

scientific article published on April 1, 1992

Transcription-coupled recruitment of human CHD1 and CHD2 influences chromatin accessibility and histone H3 and H3.3 occupancy at active chromatin regions

scientific article published on 15 January 2015

Transcriptional regulation at the yeast nuclear envelope

scientific article

Transient inhibition of histone deacetylase activity overcomes silencing in the mating-type region in fission yeast

scientific article published on 01 March 1999

Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres.

scientific article published in December 1997

ago1 and dcr1, two core components of the RNA interference pathway, functionally diverge from rdp1 in regulating cell cycle events in Schizosaccharomyces pombe

scientific article published on 29 December 2003

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