List of works by Clara Ràfols

A comparison between different approaches to estimate the aqueous pKa values of several non-steroidal anti-inflammatory drugs

article

A fast high throughput method for the determination of acidity constants by capillary electrophoresis. 3. Basic internal standards.

scientific article published on 27 April 2011

A fast method for pKa determination by capillary electrophoresis.

scientific article published in November 2009

A potentially simpler approach to measure aqueous pKa of insoluble basic drugs containing amino groups.

scientific article

Acidity and Hydrophobicity of Several New Potential Antitubercular Drugs: Isoniazid and Benzimidazole Derivatives

Acidity of several polyprotic acids, amiodarone and quetiapine hemifumarate in pure methanol

scientific article

Acid−Base Dissociation Constants ofo-Phthalic Acid in Acetonitrile/Water Mixtures over the (15 to 50) °C Temperature Range and Related Thermodynamic Quantities

Autoprotolysis in aqueous organic solvent mixtures. Water/alcohol binary systems

Autoprotolysis in aqueous organic solvent mixtures. Water/dipolar protophilic solvent binary systems

Binding thermodynamics of paromomycin, neomycin, neomycin-dinucleotide and -diPNA conjugates to bacterial and human rRNA.

scientific article published on 4 November 2015

Characterization of the Solvation Properties of Sodiumn-Dodecyl Sulfate Micelles in Buffered and Unbuffered Aqueous Phases by Solvatochromic Indicators

Chromatographic determination of aqueous dissociation constants of some water-insoluble nonsteroidal antiinflammatory drugs.

scientific article published in April 2002

Chromatographic hydrophobicity index: pH profile for polyprotic compounds

scientific article published on 17 September 2009

Critical comparison of shake-flask, potentiometric and chromatographic methods for lipophilicity evaluation (log P o/w ) of neutral, acidic, basic, amphoteric, and zwitterionic drugs

scientific article published on 10 July 2018

Critical micelle concentration of surfactants in aqueous buffered and unbuffered systems

Critical validation of a new simpler approach to estimate aqueous pKa of drugs sparingly soluble in water

article

Determination of acidity constants by the capillary electrophoresis internal standard method. IV. Polyprotic compounds

scientific article published on 10 January 2013

Determination of mono- and disulphonated azo dyes by liquid chromatography–atmospheric pressure ionization mass spectrometry

scientific article

Determination of sulphonated azo dyes in water and wastewater

article by J Riu et al published August 1997 in Trends in Analytical Chemistry

Effect of temperature on pH measurements and acid-base equilibria in methanol-water mixtures

scientific article published in June 2003

Effect of temperature on the chromatographic retention of ionizable compounds. I. Methanol-water mobile phases

scientific article

Effect of temperature on the chromatographic retention of ionizable compounds. II. Acetonitrile-water mobile phases

scientific article published in June 2005

Effect of temperature on the chromatographic retention of ionizable compounds. III. Modeling retention of pharmaceuticals as a function of eluent pH and column temperature in RPLC.

scientific article published in April 2008

Effect of vinylpyrrolidone polymers on the solubility and supersaturation of drugs; a study using the Cheqsol method.

scientific article published on 23 February 2018

Erratum to “Solute–solvent interactions in micellar electrokinetic chromatography. III. Characterization of the selectivity of micellar electrokinetic chromatography systems” [J. Chromatogr. A 942 (2002) 237–248]

scholarly article published in Journal of Chromatography

Extension of the liquid chromatography/quantitative structure–property relationship method to assess the lipophilicity of neutral, acidic, basic and amphotheric drugs

scientific article published on 05 April 2012

Hydrophobic and cation exchange mechanisms in the retention of basic compounds in a polymeric column

scientific article published in February 2004

Ionic equilibria in aqueous organic solvent mixtures The equilibria of HF in an ethanol + water mixture used for cleaning up semiconductors

Ionic equilibria in aqueous organic solvent mixtures the dissociation constants of acids and salts in tetrahydrofuran/water mixtures

Lipophilicity assessment of basic drugs (logPo/w determination) by a chromatographic method

scientific article published on 08 July 2011

Lipophilicity of amphoteric and zwitterionic compounds: A comparative study of determination methods

scientific article published on 10 October 2016

Micellar electrokinetic chromatography estimation of size and composition of procyanidins after thiolysis with cysteine

scientific article published in May 2003

Mixed micellar electrokinetic capillary chromatography separation of depolymerized grape procyanidins

scientific article published in February 2003

Molecular details of INH-C10 binding to wt KatG and Its S315T mutant.

scientific article published on 3 February 2015

Molecular interactions between some non-steroidal anti-inflammatory drugs (NSAID׳s) and bovine (BSA) or human (HSA) serum albumin estimated by means of isothermal titration calorimetry (ITC) and frontal analysis capillary electrophoresis (FA/CE)

article

Molecular interactions between warfarin and human (HSA) or bovine (BSA) serum albumin evaluated by isothermal titration calorimetry (ITC), fluorescence spectrometry (FS) and frontal analysis capillary electrophoresis (FA/CE).

scientific article published on 18 December 2017

Phenothiazines solution complexity - Determination of pKa and solubility-pH profiles exhibiting sub-micellar aggregation at 25 and 37°C.

scientific article published on 20 July 2016

Poly(2-Ethyl-2-Oxazoline) as an Alternative to Poly(Vinylpyrrolidone) in Solid Dispersions for Solubility and Dissolution Rate Enhancement of Drugs

scientific article published on 31 May 2018

Potentiometric CheqSol and standardized shake-flask solubility methods are complimentary tools in physicochemical profiling

scientific article published on 14 March 2020

Prediction of retention in reversed-phase liquid chromatography by means of the polarity parameter model.

scientific article published on 13 May 2009

Selectivity of single, mixed, and modified pseudostationary phases in electrokinetic chromatography.

scientific article published in May 2006

Setup and validation of shake-flask procedures for the determination of partition coefficients (logD) from low drug amounts

scientific article

Solubility-pH profiles of some acidic, basic and amphoteric drugs.

scientific article

Solute-solvent interactions in micellar electrokinetic chromatography. 6. Optimization of the selectivity of lithium dodecyl sulfate-lithium perfluorooctanesulfonate mixed micellar buffers

scientific article published in September 2002

Solute-solvent interactions in micellar electrokinetic chromatography. Characterization of sodium dodecyl sulfate-Brij 35 micellar systems for quantitative structure-activity relationship modelling.

scientific article published in June 1999

Solute-solvent interactions in micellar electrokinetic chromatography: V. Factors that produce peak splitting

scientific article published in August 2002

Static Dielectric Constants of Acetonitrile/Water Mixtures at Different Temperatures and Debye−HückelAanda0BParameters for Activity Coefficients

Temperature variation effects on the determination of acidity constants through the internal standard-capillary electrophoresis method.

scientific article published on 8 April 2013

The Ca2+–EDTA chelation as standard reaction to validate Isothermal Titration Calorimeter measurements (ITC)

scientific article published on 25 March 2016

The contribution of the hydrogen bond acidity on the lipophilicity of drugs estimated from chromatographic measurements

scientific article

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