List of works - Ben Luisi

1.8 Å resolution crystal structure of the carbapenem intrinsic resistance protein CarF.

scientific article published on 22 June 2017

A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation

scientific article published on 21 June 2021

A critical role of a carboxylate in proton conduction by the ATP-binding cassette multidrug transporter LmrA.

scientific article published on 22 July 2005

A model of a transmembrane drug-efflux pump from Gram-negative bacteria

scientific article published in December 2004

A processed noncoding RNA regulates an altruistic bacterial antiviral system

scientific article

Allosteric mutants show that PrfA activation is dispensable for vacuole escape but required for efficient spread and Listeria survival in vivo

scientific article

Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation

scientific article published on 13 November 2003

An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump

scientific article

An ancient anion-binding structural module in RNA and DNA helicases

scientific article

Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes ⬇️

scientific article

Architectural principles for Hfq/Crc-mediated regulation of gene expression

article

Assembly and Channel Opening in a Bacterial Drug Efflux Machine

scientific article

BM0701: Antibiotic Transport and Efflux: New Strategies to Combat Bacterial Resistance (ATENS)

scholarly article by Jean-Marie Pages et al published 1 February 2011 in Letters in drug design & discovery

Balancing at survival's edge: the structure and adaptive benefits of prokaryotic toxin-antitoxin partners.

scientific article published on February 2011

Central dogma alchemy

scientific article published on April 2015

Computational design of transmembrane pores

scientific article published on 26 August 2020

Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction

scientific article published on 31 March 2022

Crystal Structure of Escherichia coli Polynucleotide Phosphorylase Core Bound to RNase E, RNA and Manganese: Implications for Catalytic Mechanism and RNA Degradosome Assembly

scientific article

Crystal structure of Caulobacter crescentus polynucleotide phosphorylase reveals a mechanism of RNA substrate channelling and RNA degradosome assembly ⬇️

scientific article published on April 1, 2012

Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex

scientific article

Crystal structures of engrailed homeodomain mutants: implications for stability and dynamics

scientific article

Cytochrome c6A: discovery, structure and properties responsible for its low haem redox potential

scientific article published on December 2008

Direct observation of processive exoribonuclease motion using optical tweezers

scientific article

Dymer, dymer binding tight

scientific article published in Nature

Endonucleolytic initiation of mRNA decay in Escherichia coli

scientific article published on January 2009

From conformational chaos to robust regulation: the structure and function of the multi-enzyme RNA degradosome

scientific article (publication date: 14 December 2011)

Hfq and its constellation of RNA

scientific article (publication date: 15 August 2011)

High thermodynamic stability of parametrically designed helical bundles

scientific article published on October 2014

Identification and classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes.

scientific article

In situ structure and assembly of the multidrug efflux pump AcrAB-TolC.

scientific article published on 14 June 2019

Information available at cut rates: structure and mechanism of ribonucleases

scientific article published on 26 December 2006

Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis

scientific article published on 05 March 2014

In Vivo Cleavage Map Illuminates the Central Role of RNase E in Coding and Non-coding RNA Pathways

scientific article

Kiyoshi Nagai (1949-2019)

scientific article published on 01 January 2020

Licensing and due process in the turnover of bacterial RNA.

scientific article published on April 2013

Membrane recognition and dynamics of the RNA degradosome

scientific article

Metal-dependent folding and stability of nuclear hormone receptor DNA-binding domains

scientific article

Modulation of heme redox potential in the cytochrome c6 family

scientific article

Molecular recognition betweenEscherichia colienolase and ribonuclease E

scientific article

Multidrug efflux pumps: structure, function and regulation

scientific article published on 01 September 2018

Nanopore-based identification of individual nucleotides for direct RNA sequencing ⬇️

scientific article

Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli.

scientific article

Potential Regulatory Interactions of Escherichia coli RraA Protein with DEAD-box Helicases

scientific article

Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation

scientific article

Quaternary structure and catalytic activity of the Escherichia coli ribonuclease E amino-terminal catalytic domain.

scientific article

RNA lifetime control, from stereochemistry to gene expression

scientific article published on 21 December 2019

RNase E and the High-Fidelity Orchestration of RNA Metabolism

scientific article published on 01 April 2018

Rarely at rest: RNA helicases and their busy contributions to RNA degradation, regulation and quality control

scientific article published on 12 October 2012

Recognition of the small regulatory RNA RydC by the bacterial Hfq protein

scientific article

Running rings around RNA: a superfamily of phosphate-dependent RNases.

scientific article

Selectivity and self-assembly in the control of a bacterial toxin by an antitoxic noncoding RNA pseudoknot

scientific article

Snapshots of Catalysis in the E1 Subunit of the Pyruvate Dehydrogenase Multienzyme Complex

scientific article

Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46

scientific article

Structural Insights into the Prereaction State of Pyruvate Decarboxylase from Zymomonas mobilis ,

scientific article

Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5

scientific article published on 06 September 2021

Structure and mechanism of bacterial tripartite efflux pumps

scientific article published on 19 May 2018

Structure and mechanism of drug efflux machinery in Gram negative bacteria

scientific article published on September 2008

Structure of the AcrAB–TolC multidrug efflux pump

scientific article

Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII

scientific article

Structure of the periplasmic domain of Pseudomonas aeruginosa TolA: evidence for an evolutionary relationship with the TonB transporter protein

scientific article

Structure, mechanism and cooperation of bacterial multidrug transporters

scientific article

Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E.

scientific article published in July 2004

Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E

scholarly article by Katarzyna J Bandyra published in September 2018

Targeting the Conserved Stem Loop 2 Motif in the SARS-CoV-2 Genome

scientific article

The Crystal Structure of the Escherichia coli RNase E Apoprotein and a Mechanism for RNA Degradation

scientific article

The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 A resolution.

scientific article

The export of coat protein from enteroaggregative Escherichia coli by a specific ATP-binding cassette transporter system

scientific article published on 21 August 2003

The regulatory protein RraA modulates RNA-binding and helicase activities of the E. coli RNA degradosome

scientific article

The ribonuclease polynucleotide phosphorylase can interact with small regulatory RNAs in both protective and degradative modes.

scientific article published on 12 January 2016

The seed region of a small RNA drives the controlled destruction of the target mRNA by the endoribonuclease RNase E.

scientific article published on 16 August 2012

The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis

scientific article published on 08 June 2022

Zinc standard for economy

scientific article published in Nature

List of works by Ben Luisi

1.8 Å resolution crystal structure of the carbapenem intrinsic resistance protein CarF.

A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation

A critical role of a carboxylate in proton conduction by the ATP-binding cassette multidrug transporter LmrA.

A model of a transmembrane drug-efflux pump from Gram-negative bacteria

A processed noncoding RNA regulates an altruistic bacterial antiviral system

Allosteric mutants show that PrfA activation is dispensable for vacuole escape but required for efficient spread and Listeria survival in vivo

Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation

An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump

An ancient anion-binding structural module in RNA and DNA helicases

Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes ⬇️

Architectural principles for Hfq/Crc-mediated regulation of gene expression

Assembly and Channel Opening in a Bacterial Drug Efflux Machine

BM0701: Antibiotic Transport and Efflux: New Strategies to Combat Bacterial Resistance (ATENS)

Balancing at survival's edge: the structure and adaptive benefits of prokaryotic toxin-antitoxin partners.

Central dogma alchemy

Computational design of transmembrane pores

Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction

Crystal Structure of Escherichia coli Polynucleotide Phosphorylase Core Bound to RNase E, RNA and Manganese: Implications for Catalytic Mechanism and RNA Degradosome Assembly

Crystal structure of Caulobacter crescentus polynucleotide phosphorylase reveals a mechanism of RNA substrate channelling and RNA degradosome assembly ⬇️

Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex

Crystal structures of engrailed homeodomain mutants: implications for stability and dynamics

Cytochrome c6A: discovery, structure and properties responsible for its low haem redox potential

Direct observation of processive exoribonuclease motion using optical tweezers

Dymer, dymer binding tight

Endonucleolytic initiation of mRNA decay in Escherichia coli

From conformational chaos to robust regulation: the structure and function of the multi-enzyme RNA degradosome

Hfq and its constellation of RNA

High thermodynamic stability of parametrically designed helical bundles

Identification and classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes.

In situ structure and assembly of the multidrug efflux pump AcrAB-TolC.

Information available at cut rates: structure and mechanism of ribonucleases

Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis

In Vivo Cleavage Map Illuminates the Central Role of RNase E in Coding and Non-coding RNA Pathways

Kiyoshi Nagai (1949-2019)

Licensing and due process in the turnover of bacterial RNA.

Membrane recognition and dynamics of the RNA degradosome

Metal-dependent folding and stability of nuclear hormone receptor DNA-binding domains

Modulation of heme redox potential in the cytochrome c6 family

Molecular recognition betweenEscherichia colienolase and ribonuclease E

Multidrug efflux pumps: structure, function and regulation

Nanopore-based identification of individual nucleotides for direct RNA sequencing ⬇️

Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli.

Potential Regulatory Interactions of Escherichia coli RraA Protein with DEAD-box Helicases

Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation

Quaternary structure and catalytic activity of the Escherichia coli ribonuclease E amino-terminal catalytic domain.

RNA lifetime control, from stereochemistry to gene expression

RNase E and the High-Fidelity Orchestration of RNA Metabolism

Rarely at rest: RNA helicases and their busy contributions to RNA degradation, regulation and quality control

Recognition of the small regulatory RNA RydC by the bacterial Hfq protein

Running rings around RNA: a superfamily of phosphate-dependent RNases.

Selectivity and self-assembly in the control of a bacterial toxin by an antitoxic noncoding RNA pseudoknot

Snapshots of Catalysis in the E1 Subunit of the Pyruvate Dehydrogenase Multienzyme Complex

Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46

Structural Insights into the Prereaction State of Pyruvate Decarboxylase from Zymomonas mobilis ,

Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5

Structure and mechanism of bacterial tripartite efflux pumps

Structure and mechanism of drug efflux machinery in Gram negative bacteria

Structure of the AcrAB–TolC multidrug efflux pump

Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII

Structure of the periplasmic domain of Pseudomonas aeruginosa TolA: evidence for an evolutionary relationship with the TonB transporter protein

Structure, mechanism and cooperation of bacterial multidrug transporters

Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E.

Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E

Targeting the Conserved Stem Loop 2 Motif in the SARS-CoV-2 Genome

The Crystal Structure of the Escherichia coli RNase E Apoprotein and a Mechanism for RNA Degradation

The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 A resolution.

The export of coat protein from enteroaggregative Escherichia coli by a specific ATP-binding cassette transporter system

The regulatory protein RraA modulates RNA-binding and helicase activities of the E. coli RNA degradosome

The ribonuclease polynucleotide phosphorylase can interact with small regulatory RNAs in both protective and degradative modes.

The seed region of a small RNA drives the controlled destruction of the target mRNA by the endoribonuclease RNase E.

The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis

Zinc standard for economy