List of works by Patrizia Casaccia

A metabolic perspective on CSF-mediated neurodegeneration in multiple sclerosis

scientific article published on 01 September 2019

An integrated approach to design novel therapeutic interventions for demyelinating disorders

scientific article

Anti-TANKyrase weapons promote myelination

scientific article published on 26 July 2011

Aspartoacylase deficiency affects early postnatal development of oligodendrocytes and myelination

scientific article published on 14 July 2010

Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions

scientific article published on 4 April 2017

Axonal damage in multiple sclerosis.

scientific article

Bioenergetic Failure in Rat Oligodendrocyte Progenitor Cells Treated with Cerebrospinal Fluid Derived from Multiple Sclerosis Patients

scientific article

Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course

scientific article published on 10 April 2019

Brain Cell Type Specific Gene Expression and Co-expression Network Architectures.

scientific article published on 11 June 2018

Bromodomains: Translating the words of lysine acetylation into myelin injury and repair

scientific article

Cell-context specific role of the E2F/Rb pathway in development and disease

scientific article published on March 2010

Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics

scientific article

Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions

scientific article

Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation.

scientific article

Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice.

scientific article

Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination

scientific article

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

scientific article

Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia.

scientific article published on July 2013

Correction: Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination (doi:10.1242/dev.106492)

scientific article published on 13 July 2018

DNA methylation in oligodendroglial cells during developmental myelination and in disease

scientific article published on 31 January 2017

Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression

scientific article

Defining the chromatin landscape in demyelinating disorders

scientific article published on 22 October 2009

Differential modulation of the oligodendrocyte transcriptome by sonic hedgehog and bone morphogenetic protein 4 via opposing effects on histone acetylation

scientific journal article

Disease-modifying therapies alter gut microbial composition in MS

scientific article published on 26 October 2018

Does the gut microbiota contribute to the oligodendrocyte progenitor niche?

scientific article published on 25 October 2019

Dynamic Lamin B1-Gene Association During Oligodendrocyte Progenitor Differentiation

scientific article published on 04 February 2020

E2F1 coregulates cell cycle genes and chromatin components during the transition of oligodendrocyte progenitors from proliferation to differentiation

scientific article published on January 2014

EPIGENETIC MECHANISMS IN MULTIPLE SCLEROSIS

scientific article published on 01 March 2014

Efficient Remyelination Requires DNA Methylation

scientific article published on 30 March 2017

Emerging concepts in neuroscience research: 2019 highlights

scientific article published on 01 January 2020

Epigenetic Modulation of Human Induced Pluripotent Stem Cell Differentiation to Oligodendrocytes

scientific article

Epigenetic control of oligodendrocyte development: adding new players to old keepers

scientific article published on 13 June 2016

Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatment

scientific article published on February 2013

Epigenetic modifications in brain and immune cells of multiple sclerosis patients

scientific article published in January 2018

Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells

scientific article

Epigenetic regulation of oligodendrocyte identity

scientific article published on 12 March 2010

Epigenetics in NG2 glia cells

scientific article published on 17 June 2015

Epigenome-wide differences in pathology-free regions of multiple sclerosis-affected brains

scientific article

Epigenomic signature of adrenoleukodystrophy predicts compromised oligodendrocyte differentiation.

scientific article published on 24 February 2018

Foreword

scientific article published on 20 May 2020

Fumarates target the metabolic-epigenetic interplay of brain-homing T cells in multiple sclerosis

scientific article published on 01 March 2019

Gene expression abnormalities and oligodendrocyte deficits in the internal capsule in schizophrenia

scientific article

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models.

scientific article published on 11 September 2017

Gut-brain communication in demyelinating disorders

scientific article published on 14 February 2020

HDAC inhibitors and neurodegeneration: at the edge between protection and damage

scientific article published on February 2010

HDAC1 in axonal degeneration: A matter of subcellular localization

scientific article

HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage

scientific article

Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation

scholarly article

Identification of a gene regulatory network necessary for the initiation of oligodendrocyte differentiation

scientific article published in 2011

Impaired adult myelination in the prefrontal cortex of socially isolated mice

scientific article

Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease

scientific article

Interplay between transcriptional control and chromatin regulation in the oligodendrocyte lineage

scientific article published on 12 May 2015

Introduction to the special issue on myelin plasticity in the central nervous system

scientific article published in February 2018

Maternal cannabis use alters ventral striatal dopamine D2 gene regulation in the offspring

scientific article

Mechano-modulation of nuclear events regulating oligodendrocyte progenitor gene expression

scientific article published on 08 February 2019

Mechanostimulation Promotes Nuclear and Epigenetic Changes in Oligodendrocytes

scientific article

Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior.

scientific article published on 20 April 2016

Multiple Sclerosis-Associated Changes in the Composition and Immune Functions of Spore-Forming Bacteria

article

Multiple sclerosis patient-derived CSF induces transcriptional changes in proliferating oligodendrocyte progenitors

scientific article published on 6 May 2015

Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease

scientific article published on 6 November 2017

Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination

scientific article published on 23 February 2015

PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination

scientific article published on 01 April 2019

PRMT5-mediated regulation of developmental myelination

scientific article published in Nature Communications

Primary brain tumors, neural stem cell, and brain tumor cancer cells: where is the link?

scientific article

Progressive multiple sclerosis and gray matter pathology: an MRI perspective

scientific article

Promoting return of function in multiple sclerosis: An integrated approach

scientific article published on October 2013

Region-specific myelin differences define behavioral consequences of chronic social defeat stress in mice

scientific article published on 13 August 2019

Retrograde Degenerative Signaling Mediated by the p75 Neurotrophin Receptor Requires p150Glued Deacetylation by Axonal HDAC1

scientific article published on 01 August 2018

Role of Tet1 and 5-hydroxymethylcytosine in cocaine action

scientific article

Roles of p53 and p27(Kip1) in the regulation of neurogenesis in the murine adult subventricular zone

scientific article published on 7 September 2011

Selective Chemical Modulation of Gene Transcription Favors Oligodendrocyte Lineage Progression

scientific article

Shaping the oligodendrocyte identity by epigenetic control

scientific article

Sox2 Sustains Recruitment of Oligodendrocyte Progenitor Cells following CNS Demyelination and Primes Them for Differentiation during Remyelination.

scientific article published on August 2015

Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation.

scientific article

The Chromatin Environment Around Interneuron Genes in Oligodendrocyte Precursor Cells and Their Potential for Interneuron Reprograming

scientific article published on 08 August 2019

The Microbiome-Gut-Behavior Axis: Crosstalk Between the Gut Microbiome and Oligodendrocytes Modulates Behavioral Responses

scientific article

The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination

scientific article (publication date: May 2016)

Two-tier transcriptional control of oligodendrocyte differentiation

scientific article

Wellness and multiple sclerosis: The National MS Society establishes a Wellness Research Working Group and research priorities.

scientific article published on January 2017

Widespread transcriptional alternations in oligodendrocytes in the adult mouse brain following chronic stress.

scientific article published on 8 September 2017

Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination

scientific article

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