List of works by John R. Mascola

1272. Feasibility and Successful Enrollment in Proof-of-Concept Trials to Assess Safety and Efficacy of a Broadly Neutralizing Monoclonal Antibody, VRC01, to Prevent HIV-1 Acquisitionin in Uninfected Individuals

454 pyrosequencing and bioinformatics analysis of the lineage of the broad and potent gp41-directed antibody 10e8.

scientific article published on 13 September 2012

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

scientific article (publication date: 2015)

A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge

scientific article published on 01 September 2019

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.

scientific article published on 7 March 2018

A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial

scientific article published on 26 September 2008

A Virus-Like Particle Vaccine Elicits Broad Neutralizing Antibody Responses in Humans to All Chikungunya Virus Genotypes

scientific article published on 21 September 2016

A West Nile Virus DNA Vaccine Induces Neutralizing Antibody in Healthy Adults during a Phase 1 Clinical Trial

scientific article (publication date: 15 December 2007)

A West Nile virus DNA vaccine utilizing a modified promoter induces neutralizing antibody in younger and older healthy adults in a phase I clinical trial

scientific article

A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice

scientific article published on 26 January 2022

A computational framework for the analysis of peptide microarray antibody binding data with application to HIV vaccine profiling

scientific article published on 13 June 2013

A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates

scientific article

A human monoclonal antibody specific for the V3 loop of HIV type 1 clade E cross-reacts with other HIV type 1 clades.

scientific article

A human monoclonal antibody to a complex epitope in the V3 region of gp120 of human immunodeficiency virus type 1 has broad reactivity within and outside clade B.

scientific article published in January 1995

A method for identification of HIV gp140 binding memory B cells in human blood

scientific article

A pH-dependent switch mediates conformational masking of SARS-CoV-2 spike

scientific article published on 04 July 2020

A phase I/II trial of HIV SF2 gp120/MF59 vaccine in seronegative Thais

article

A platform incorporating trimeric antigens into self-assembling nanoparticles reveals SARS-CoV-2-spike nanoparticles to elicit substantially higher neutralizing responses than spike alone

scientific article published on 23 October 2020

A proof of concept for structure-based vaccine design targeting RSV in humans

scientific article published on 01 August 2019

A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults

scientific article published on 27 October 2010

A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies.

scientific article published on 13 September 2012

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies

scientific article

A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

scientific article published on 27 April 2016

A strategic approach to COVID-19 vaccine R&D

scientific article published on 11 May 2020

A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates

scientific article published on 01 May 2019

A1 The role of virus-antibody co-evolution in the development of a V3-glycan-directed HIV-1 broadly neutralizing antibody lineage

AIDS vaccines. Are we ready for human efficacy trials?

scientific article published on 01 August 1994

Accumulation of follicular CD8+ T cells in pathogenic SIV infection.

scientific article

Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates

scientific article published on 11 October 2019

Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin

scientific article published on 23 July 2019

Activation and lysis of human CD4 cells latently infected with HIV-1

scientific article

Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus

scientific article published on 26 October 2017

An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes.

scientific article published on 10 October 2016

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

scientific article published on 10 March 2014

An avian influenza H7 DNA priming vaccine is safe and immunogenic in a randomized phase I clinical trial

scientific article published in June 2017

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

scientific article published on 14 July 2020

Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trial

scientific article

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

scientific article

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

scientific article

Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals

scientific article

Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles

scientific article published on 26 December 2007

Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.

scientific article published in January 2005

Anti-HIV B Cell lines as candidate vaccine biosensors

scientific article published on 12 October 2012

Anti-HIV-1 response elicited in rabbits by anti-idiotype monoclonal antibodies mimicking the CD4-binding site

scientific article

Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline

scientific article

Antibodies with specificity to native gp120 and neutralization activity against primary human immunodeficiency virus type 1 isolates elicited by immunization with oligomeric gp160.

scientific article published in June 1997

Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk

scientific article published on 01 November 2019

Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization

scientific article published on 01 July 2019

Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

scholarly article by Nicole Doria-Rose published in 2021

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

scientific article published on 8 March 2021

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

Antibody responses to envelope glycoproteins in HIV-1 infection

scientific article

Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors

scientific article published on 24 June 2009

Antibody-based HIV-1 vaccines: recent developments and future directions

scientific article published on December 2007

Antibody-dependent cell-mediated cytotoxicity in simian immunodeficiency virus-infected rhesus monkeys

scientific article

Antibody-dependent cell-mediated viral inhibition emerges after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys coincident with gp140-binding antibodies and is effective against neutralization-resistant viruses

scientific article

Antibody-dependent cellular cytotoxicity against primary HIV-infected CD4+ T cells is directly associated with the magnitude of surface IgG binding

scientific article

Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.

scientific article published in January 2017

Antigen detection in neutralization assays: high levels of interfering anti-p24 antibodies in some plasma

scientific article published on 01 December 1993

As antibody findings mount, what comes next? Interview by Kristen Jill Kresge and Regina McEnery.

scientific article published in January 2011

Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial

scientific article published on 26 November 2020

Assessing the safety and pharmacokinetics of the monoclonal antibodies, VRC07-523LS and PGT121 in HIV negative women in South Africa: study protocol for the CAPRISA 012A randomised controlled phase I trial

scientific article published on 03 July 2019

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

scientific article published on 01 June 2019

Author Correction: Next-generation influenza vaccines: opportunities and challenges

scientific article published on 01 June 2020

B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.

scientific article

BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses

scientific article

Basis and Statistical Design of the Passive HIV-1 Antibody Mediated Prevention (AMP) Test-of-Concept Efficacy Trials

scientific article

Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by semliki forest virus

scientific article

Biochemically defined HIV-1 envelope glycoprotein variant immunogens display differential binding and neutralizing specificities to the CD4-binding site

scientific article published on 13 December 2011

Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization.

scientific article

Breadth of cellular and humoral immune responses elicited in rhesus monkeys by multi-valent mosaic and consensus immunogens

scientific article published on 21 April 2012

Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

scientific article

Brief Report: Prediction of Serum HIV-1 Neutralization Titers After Passive Administration of VRC01

scientific article published on 01 April 2020

Broad HIV-1 neutralization mediated by CD4-binding site antibodies

scientific article published on 26 August 2007

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope

scientific article published on 21 May 2019

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

scientific article

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

scientific article

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

scientific article

Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region

scientific article published on 19 August 2009

Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype ⬇️

scientific article

Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

scientific article published on 3 June 2015

Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning

scientific article published in September 2013

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

scientific article published on September 2017

CD4-binding-Site Recognition by VH1-46 Germline-derived HIV-1 Neutralizers.

scientific article published in October 2014

CD8β Depletion Does Not Prevent Control of Viral Replication or Protection from Challenge in Macaques Chronically Infected with a Live Attenuated Simian Immunodeficiency Virus

scientific article published on 17 July 2019

Canarypox virus-induced maturation of dendritic cells is mediated by apoptotic cell death and tumor necrosis factor alpha secretion

scientific article published on December 2000

Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies

scientific article published on October 2003

Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote.

scientific article

Characteristics of HIV-1 gp120 molecules that bind ancestor, intermediate and mature forms of VRC01-like antibodies

article

Characterization of a human monoclonal antibody generated from a B-cell specific for a prefusion-stabilized spike protein of Middle East respiratory syndrome coronavirus

scientific article published on 08 May 2020

Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants

scientific article

Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors.

scientific article

Characterization of complete HIV type 1 genomes from non-B subtype infections in U.S. military personnel

scientific article

Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity ⬇️

scientific article published on 14 March 2007

Characterization of the Neutralizing Antibody Response in a Case of Genetically Linked HIV Superinfection

article

Characterizing the fitness cost of viral escape from the HIV-1 broadly neutralizing monoclonal antibody VRC01

article

Chimpanzee Adenovirus Vector Ebola Vaccine — Preliminary Report

scientific article

Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge

scientific article

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

scientific article

Combination recombinant simian or chimpanzee adenoviral vectors for vaccine development

scientific article published on 26 October 2015

Comparative evaluation of three different intramuscular delivery methods for DNA immunization in a nonhuman primate animal model

scientific article published on 9 August 2005

Comparison of adjuvants to optimize influenza neutralizing antibody responses

scientific article published on 05 September 2019

Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV

article

Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting

article

Construction and biological characterization of infectious molecular clones of HIV-1 subtypes B and E (CRF01_AE) generated by the polymerase chain reaction

scientific article published on 01 December 2000

Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor

scientific article published on 29 June 2020

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

scientific article

Correction for Acharya et al., Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

article

Correction for Chakrabarti et al., Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates.

scientific article published on 16 December 2014

Correction for Hraber et al., "Panels of HIV-1 Subtype C Env Reference Strains for Standardized Neutralization Assessments".

scientific article

Correction for Ingale et al., Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies

scientific article published on June 2015

Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies

article

Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

scientific article published on 02 December 2019

Correction: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

scientific article published on 24 May 2016

Correlation between humoral responses to human immunodeficiency virus type 1 envelope and disease progression in early-stage infection

scientific article published in November 1998

Cross-Reactive HIV-1-Neutralizing Human Monoclonal Antibodies Identified from a Patient with 2F5-Like Antibodies

Cross-clade recognition and neutralization by the V3 region from clade C human immunodeficiency virus-1 envelope

scientific article published on 18 April 2006

Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies

scientific article

Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens

scientific article published on 14 May 2008

Cross-subtype neutralizing antibodies induced in baboons by a subtype E gp120 immunogen based on an R5 primary human immunodeficiency virus type 1 envelope

scientific article

Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

scientific article published on 17 November 2020

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

scientific article published on 11 December 2019

Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

scientific article

Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

scientific article

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

scientific article

Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.

scientific article

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials

scientific article published on 03 October 2011

DNA vaccine delivered by a needle-free injection device improves potency of priming for antibody and CD8+ T-cell responses after rAd5 boost in a randomized clinical trial

scientific article

De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts

scientific article published on 08 October 2013

Deep sequencing with longitudinal sampling of a VRC01-like-antibody response in a chronically infected individual

scientific article published on 13 September 2012

Defining the Protective Antibody Response for HIV-1 ⬇️

scientific article published on May 1, 2003

Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques

scientific article published on 13 May 2019

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

scientific article

Demonstration of de novo HIV type 1 production by detection of multiply spliced and unspliced HIV type 1 RNA in paraffin-embedded tonsils

scientific article published on July 2002

Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection

scientific article

Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages

scientific article published on 26 February 2019

Design of an HIV Env antigen that binds with high affinity to antibodies against linear, conformational and broadly neutralizing epitopes within V1/V2.

scientific article published on 13 September 2012

Design of epitope-specific probes for sera analysis and antibody isolation

scientific article (publication date: 2012)

Detection of Broadly Neutralizing Activity within the First Months of HIV-1 Infection.

scientific article published on 16 March 2016

Detection of diverse HIV-1 genetic subtypes in the USA

scientific article published on 01 November 1995

Determination of HIV-1 Chemokine Coreceptor Tropism Using Transduced Human Osteosarcoma (HOS) Cells

scientific article published on January 1999

Determination of Syncytium-Inducing Phenotype of Primary HIV-1 Isolates Using MT-2 cells

scientific article published on January 1999

Development of a 3Mut-Apex-Stabilized Envelope Trimer that Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses

scientific article published on 15 April 2020

Development of a potent Zika virus vaccine using self-amplifying messenger RNA

scientific article published on 07 August 2020

Development of calibrated viral load standards for group M subtypes of human immunodeficiency virus type 1 and performance of an improved AMPLICOR HIV-1 MONITOR test with isolates of diverse subtypes

scientific article

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

scientific article

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

scientific article

Differential susceptibility to human immunodeficiency virus type 1 infection of myeloid and plasmacytoid dendritic cells

scientific article

Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations

scientific article published on 01 July 2019

Disseminated gonococcal infection.

scientific article

Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality

scientific article published on 01 June 2020

Diverse HIV-1 subtypes and clinical, laboratory and behavioral factors in a recently infected US military cohort ⬇️

scientific article published on November 21, 2003

Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization

scientific article published on 11 May 2015

Diversity of the envelope glycoprotein among human immunodeficiency virus type 1 isolates of clade E from Asia and Africa

scientific article published in June 1996

Drug resistance patterns, genetic subtypes, clinical features, and risk factors in military personnel with HIV-1 seroconversion

scientific article published on October 1999

Dual infection with human immunodeficiency virus type 1 of distinct envelope subtypes in humans

scientific article

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination

scientific article published on 03 December 2020

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

scientific article

Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants

scientific article

Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes.

scientific article

Early short-term antiretroviral therapy is associated with a reduced prevalence of CD8(+)FoxP3(+) T cells in simian immunodeficiency virus-infected controller rhesus macaques

scientific article

Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques

scientific article published on 21 March 2016

Editorial overview: Vaccines: Vaccines for cancer and infectious diseases

scientific article published on 11 August 2015

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

scientific article

Effect of a Chikungunya Virus-Like Particle Vaccine on Safety and Tolerability Outcomes: A Randomized Clinical Trial

scientific article published on 01 April 2020

Effect of rAd5-Vector HIV-1 Preventive Vaccines on HIV-1 Acquisition: A Participant-Level Meta-Analysis of Randomized Trials

scientific article published on 2 September 2015

Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection

scientific article

Effects of antibody on viral kinetics in simian/human immunodeficiency virus infection: implications for vaccination

scientific article published on May 2004

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

scientific article published on 30 December 2020

Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase

scientific article

Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine

scientific article

Efficient protein boosting after plasmid DNA or recombinant adenovirus immunization with HIV-1 vaccine constructs

scientific article published on 7 November 2006

Elicitation of simian immunodeficiency virus-specific cytotoxic T lymphocytes in mucosal compartments of rhesus monkeys by systemic vaccination

scientific article

Eliminating antibody polyreactivity through addition of N-linked glycosylation

scientific article published on 12 May 2015

Engineered mice and B cell lines expressing broadly neutralizing antibodies and their unmutated precursors: tools for HIV vaccinology.

scientific article published on 13 September 2012

Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain

scientific article published on 04 March 2009

Enhanced neonatal Fc receptor function improves protection against primate SHIV infection

scientific article published on 13 August 2014

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

scientific article

Enhancing the Solubility of HIV-1-neutralizing Antibody 10E8.

scientific article published in October 2014

Envelope vaccination shapes viral envelope evolution following simian immunodeficiency virus infection in rhesus monkeys

scientific article

Envelope variable region 4 is the first target of neutralizing antibodies in early simian immunodeficiency virus mac251 infection of rhesus monkeys

scientific article

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

scientific article published on 04 June 2018

Evaluation of candidate vaccine approaches for MERS-CoV.

scientific article published on 28 July 2015

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

scientific article published on 28 July 2020

Exclusive and persistent use of the entry coreceptor CXCR4 by human immunodeficiency virus type 1 from a subject homozygous for CCR5 delta32.

scientific article

Expanded breadth of virus neutralization after immunization with a multiclade envelope HIV vaccine candidate

scientific article

Exploiting glycan topography for computational design of Env glycoprotein antigenicity.

scientific article published on 20 April 2018

Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies

scientific article published on December 1994

Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses

scientific article published on 01 February 2020

Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody

scientific article published on 20 July 2020

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

scientific article

Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies

scientific article published on January 2017

Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

scientific article published on 15 October 2008

Functional Profiling of Antibody Immune Repertoires in Convalescent Zika Virus Disease Patients

scientific article

Functional interrogation and mining of natively paired human VH:VL antibody repertoires

scientific article published on 8 January 2018

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

scientific article

Gene transfer in humans using a conditionally replicating lentiviral vector

scientific article

Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation

scientific article

Gene-based vaccination with a mismatched envelope protects against simian immunodeficiency virus infection in nonhuman primates

scientific article

Genetic diversity of the envelope glycoprotein from human immunodeficiency virus type 1 isolates of African origin

scientific article published in January 1995

Genetic, antigenic and serologic characterization of human immunodeficiency virus type 1 from Indonesia

scientific article published on January 1997

Genital tract sequestration of SIV following acute infection

scientific article

Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies

scientific article

Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies

scientific article published on 31 July 2018

Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses

scientific article published on 07 February 2020

Glycan-dependent HIV-specific neutralizing antibodies bind to cells of uninfected individuals

scientific article published on 01 November 2019

Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.

scientific article published on 2 May 2018

Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity

scientific article

HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces Gp41 Antibody Immunodominance in Rhesus Macaques

scientific article published on 09 August 2017

HIV Immunology Goes Out On a Limb

scientific article published on May 2016

HIV and peacekeeping operations in Cambodia

scientific article published in November 1995

HIV type 1 Env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies

scientific article

HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate

scientific article

HIV-1 Envelope Glycan Modifications that Permit Neutralization by Germline-Reverted VRC01-Class Broadly Neutralizing Antibodies

article

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

article

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

scientific article published on 01 August 2019

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

scientific article published on 30 July 2015

HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation

scientific article published on 16 February 2016

HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure.

scientific article

HIV-1 entry at the mucosal surface: role of antibodies in protection.

scientific article

HIV-1 envelope glycoprotein trimer immunogenicity elicited in the presence of human CD4 alters the neutralization profile

scientific article

HIV-1 envelope pseudotyped viral vectors and infectious molecular clones expressing the same envelope glycoprotein have a similar neutralization phenotype, but culture in peripheral blood mononuclear cells is associated with decreased neutralization

scientific article published in September 2005

HIV-1 fitness cost associated with escape from the VRC01 class of CD4 binding site neutralizing antibodies

scientific article published on 28 January 2015

HIV-1 gp120-CD4-Induced Antibody Complex Elicits CD4 Binding Site-Specific Antibody Response in Mice

scientific article published on 17 February 2020

HIV-1 neutralization coverage is improved by combining monoclonal antibodies that target independent epitopes

scientific article published on 18 January 2012

HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins

scientific article

HIV-1 neutralizing antibodies display dual specificity for the primary and coreceptor binding sites and preferential recognition of fully-cleaved Env.

scientific article published on 13 September 2012

HIV-1 neutralizing antibodies in the genital and respiratory tracts of mice intranasally immunized with oligomeric gp160.

scientific article

HIV-1 neutralizing antibodies: understanding nature's pathways

scientific article

HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization

scientific article

HIV-1: nature's master of disguise

scientific article

HIV. The modern era of HIV-1 vaccine development

scientific article published on July 2015

HIV/AIDS: Allied responses

scientific article published in Nature

Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

scientific article

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

scientific article

Herpes simplex virus vaccines--why don't antibodies protect?

scientific article published in July 1999

Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys

scientific article

High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence.

scientific article published on 21 March 2016

High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site

scientific article published on July 2012

Homologous boosting with adenoviral serotype 5 HIV vaccine (rAd5) vector can boost antibody responses despite preexisting vector-specific immunity in a randomized phase I clinical trial

scientific article

Human Immunodeficiency Virus Type 1 Candidate Vaccine Breakthrough Infection ⬇️

scientific article published on December 1, 1995

Human Immunodeficiency Virus Type 1 Monoclonal Antibodies Suppress Acute Simian-Human Immunodeficiency Virus Viremia and Limit Seeding of Cell-Associated Viral Reservoirs

scientific article

Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies

scientific article

Human dendritic cells as targets of dengue virus infection

scientific article published on December 2001

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

scientific article (publication date: August 2005)

Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein.

scientific article

Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells

scientific article

Human immunodeficiency virus type 1 neutralizing antibody serotyping using serum pools and an infectivity reduction assay

scientific article published in September 1996

Human immunodeficiency virus type 1 strains of subtypes B and E replicate in cutaneous dendritic cell-T-cell mixtures without displaying subtype-specific tropism

scientific article published in October 1997

Human skin Langerhans cells are targets of dengue virus infection

scientific article (publication date: July 2000)

Humoral response to oligomeric human immunodeficiency virus type 1 envelope protein.

scientific article published in February 1996

Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site

Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies

scientific article

Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation

scientific article published on 01 September 2020

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Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields

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Modeling cumulative overall prevention efficacy for the VRC01 phase 2b efficacy trials.

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Monoclonal Antibodies for Prevention and Treatment of COVID-19

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Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding

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Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs.

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Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

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Neutralizing antibody quantification by flow cytometry

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New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

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Newcastle Disease Virus-Like Particles Displaying Prefusion-Stabilized SARS-CoV-2 Spikes Elicit Potent Neutralizing Responses

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Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1.

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Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

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Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04

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Partial germline reversions can increase VRC07 potency and breadth.

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Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach

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Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

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Passive transfer studies to elucidate the role of antibody-mediated protection against HIV-1.

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Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies

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Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses

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Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 DNA candidate vaccine

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Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector

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Phase 1 study of pandemic H1 DNA vaccine in healthy adults

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Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine

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Phase I clinical evaluation of seasonal influenza hemagglutinin (HA) DNA vaccine prime followed by trivalent influenza inactivated vaccine (IIV3) boost

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Phase I randomized clinical trial of VRC DNA and rAd5 HIV-1 vaccine delivery by intramuscular (i.m.), subcutaneous (s.c.) and intradermal (i.d.) administration (VRC 011)

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Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals

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Polyvalent DNA prime and envelope protein boost HIV-1 vaccine elicits humoral and cellular responses and controls plasma viremia in rhesus macaques following rectal challenge with an R5 SHIV isolate

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Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and E.

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Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections.

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Power to detect the effects of HIV vaccination in repeated low-dose challenge experiments

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Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

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Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans

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Preparation of clinical-grade recombinant canarypox-human immunodeficiency virus vaccine-loaded human dendritic cells

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Priming with DNA encoding functional trimers and boosting with soluble trimeric protein elicited tier 2 neutralizing antibodies in non-human primates

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Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.

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Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

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Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles

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Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth

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Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region

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Removal of variable domain N-linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies

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Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates

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Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains

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Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis

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Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial

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Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults.

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Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial

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Safety, Tolerability, and Pharmacokinetics of the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 in HIV-Exposed Newborn Infants

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Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults

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Safety, pharmacokinetics, and immunological activities of multiple intravenous or subcutaneous doses of an anti-HIV monoclonal antibody, VRC01, administered to HIV-uninfected adults: Results of a phase 1 randomized trial.

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Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

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Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study

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Selective Increases in HIV-Specific Neutralizing Antibody and Partial Reconstitution of Cellular Immune Responses during Prolonged, Successful Drug Therapy of HIV Infection

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Selective modification of variable loops alters tropism and enhances immunogenicity of human immunodeficiency virus type 1 envelope

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Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies

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Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses

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Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation

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Serotyping of primary human immunodeficiency virus type 1 isolates from diverse geographic locations by flow cytometry.

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Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120.

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Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

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Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization

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Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity

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Soluble CD4 broadens neutralization of V3-directed monoclonal antibodies and guinea pig vaccine sera against HIV-1 subtype B and C reference viruses

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Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

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Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

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Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies

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Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

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Specific Antibody Responses to Vaccination with Bivalent CM235/SF2 gp120: Detection of Homologous and Heterologous Neutralizing Antibody to Subtype E (CRF01.AE) HIV Type 1 ⬇️

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Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

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Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6

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Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation

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Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition

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Structural definition for a new modality of broad and potent antibody neutralization at the CD4-binding site on HIV-1 gp120.

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Structural definition of a novel CD4-induced epitope that is targeted by a single-headed immunoglobulin to effect broad and potent HIV neutralization

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Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

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Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

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Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

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Structure of BMS-806, a Small-molecule HIV-1 Entry Inhibitor, Bound to BG505 SOSIP.664 HIV-1 Env Trimer.

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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

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Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)

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Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition

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Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site

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Structure of unbound MERS-CoV spike receptor-binding domain (England1 strain)

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Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization

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Structure-Based Design of Nipah Virus Vaccines: A Generalizable Approach to Paramyxovirus Immunogen Development

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Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes ⬇️

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Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors

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Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4

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Structure-guided modification and optimization of antibody VRC07.

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Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

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Summary report: workshop on the potential risks of antibody-dependent enhancement in human HIV vaccine trials

scientific article published on 01 December 1993

Summit proceedings: Biomedical countermeasure development for emerging vector-borne viral diseases

scientific article published on 06 September 2019

Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody

scientific article published in February 2018

Sustained Delivery of a Broadly Neutralizing Antibody in Nonhuman Primates Confers Long-Term Protection against Simian/Human Immunodeficiency Virus Infection

scientific article published on 18 March 2015

Systemic and mucosal T-lymphocyte activation induced by recombinant adenovirus vaccines in rhesus monkeys

scientific article published on 05 August 2009

T-cell vaccination reduces simian immunodeficiency virus levels in semen

scientific article published on 29 July 2009

Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

scientific article

The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys

scientific article

The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120.

scientific article

The ability of an oligomeric human immunodeficiency virus type 1 (HIV-1) envelope antigen to elicit neutralizing antibodies against primary HIV-1 isolates is improved following partial deletion of the second hypervariable region

scientific article published on June 2001

The cat and mouse of HIV-1 antibody escape

scientific article

The changing face of HIV vaccine research

scientific article

The development of CD4 binding site antibodies during HIV-1 infection

scientific article

The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes

scientific article

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

scientific article

The quest for an antibody-based HIV vaccine

scientific article published on January 2017

The role of antibodies in HIV vaccines

scientific article published on January 2010

The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression

scientific article

The v3 loop is accessible on the surface of most human immunodeficiency virus type 1 primary isolates and serves as a neutralization epitope.

scientific article published on March 2004

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

scientific article

Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

scientific article

Transmission of HIV-1 subtype E in the united states

scientific article published on 01 July 1996

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

scientific article

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

scientific article

Two antigenically distinct subtypes of human immunodeficiency virus type 1: viral genotype predicts neutralization serotype

scientific article published on January 1994

Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design

scientific article published in February 2012

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

scientific article published on 16 February 2018

Uncleaved Soluble gp140 Constructs with Retained Native-like Trimer Conformation and Antigenicity.

scientific article published in October 2014

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

scientific article

Use of Enzyme-digested Virus-like Particles as Probes for Flow Cytometric Sorting of HIV-specific Neutralizing Ab-producing B-cells.

scientific article published in October 2014

Use of broadly neutralizing antibodies for HIV-1 prevention

scientific article published on January 2017

VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage

scientific article published on 03 March 2020

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

scientific article published on 12 November 2019

Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses

scientific article

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

scientific article

Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models

scientific article published in December 2017

Vaccine reactions

scientific article published on 01 July 1998

Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site

scientific article

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

scientific article

Vaccine-elicited memory cytotoxic T lymphocytes contribute to Mamu-A*01-associated control of simian/human immunodeficiency virus 89.6P replication in rhesus monkeys

scientific article

Vaccines for the prevention of HIV-1 disease

scientific article

Vaccines: engineering immune evasion

scientific article published in May 2006

Variable Dependence on Glycan Recognition within a Lineage of V1V2-directed HIV Neutralizing Antibodies.

scientific article published in October 2014

Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge

scientific article published on 05 December 2018

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

scientific article

Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection

scientific article published on December 2015

Virological Control by the CD4-Binding Site Antibody N6 in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys

scientific article published on 24 May 2017

Virus-Like Particle Based Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide

scientific article published on 15 December 2020

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

scientific article published on May 2017

Virus-specific cellular immune correlates of survival in vaccinated monkeys after simian immunodeficiency virus challenge

scientific article

Which New Health Technologies Do We Need to Achieve an End to HIV/AIDS?

scientific article

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