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List of works by Karl-Ludwig Laugwitz

2-year clinical and angiographic outcomes from a randomized trial of polymer-free dual drug-eluting stents versus polymer-based Cypher and Endeavor [corrected] drug-eluting stents

scientific article published on 22 April 2010

A comparative cohort study on personalised antiplatelet therapy in PCI-treated patients with high on-clopidogrel platelet reactivity

scientific article published on 10 April 2014

A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells

scientific article published on 28 July 2016

A potential life-threatening complication after implantation of a bioresorbable scaffold for coronary stenting within a mechanically stressed region

scientific article published on 20 January 2015

Abciximab and Heparin versus Bivalirudin for Non–ST-Elevation Myocardial Infarction ⬇️

scientific article published on November 13, 2011

Accuracy of Calcium Scoring calculated from contrast-enhanced Coronary Computed Tomography Angiography using a dual-layer spectral CT: A comparison of Calcium Scoring from real and virtual non-contrast data

scientific article published in PLoS ONE

Angiographic and clinical outcomes of patients treated with drug-coated balloon angioplasty for in-stent restenosis after coronary bifurcation stenting with a two-stent technique

scientific article published on 6 December 2016

Aspirin treatment and outcomes after percutaneous coronary intervention: results of the ISAR-ASPI registry

scientific article

Assessment of mean respiratory rate from ECG recordings for risk stratification after myocardial infarction

scientific article published on 4 May 2014

Association of Toll-like receptor 4 polymorphism with age-dependent systolic blood pressure increase in patients with coronary artery disease

scientific article published on 20 May 2015

Association of increased CD8+ and persisting C-reactive protein levels with restenosis in HIV patients after coronary stenting

scientific article

Association of progression or regression of coronary artery atherosclerosis with long-term prognosis

scientific article published on 6 May 2016

Balloon angioplasty versus stenting for pulmonary vein stenosis after pulmonary vein isolation for atrial fibrillation: A meta-analysis

scientific article published on 6 December 2017

Bare metal vs. drug-eluting stents for extracranial vertebral artery disease: a meta-analysis of nonrandomized comparative studies

scientific article published on October 2014

Biodegradable polymer versus permanent polymer drug-eluting stents and everolimus- versus sirolimus-eluting stents in patients with coronary artery disease: 3-year outcomes from a randomized clinical trial

scientific article published in September 2011

Bleeding after percutaneous coronary intervention in women and men matched for age, body mass index, and type of antithrombotic therapy

scientific article published on 6 August 2013

Bleeding after percutaneous coronary intervention with Bivalirudin or unfractionated Heparin and one-year mortality

scientific article published on 14 November 2009

Cardiac MOLLI T1 mapping at 3.0 T: comparison of patient-adaptive dual-source RF and conventional RF transmission

scientific article published on 30 January 2017

Cardiac development: from current understanding to new regenerative concepts

scientific article published on March 2017

Clinical outcomes of patients treated with Nobori biolimus-eluting stent: Meta-analysis of randomized trials

scientific article published on 28 June 2014

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

scientific article published on 2 March 2016

Combination of factor Xa inhibition and antiplatelet therapy after stenting in patients with iliofemoral post-thrombotic venous obstruction

scientific article

Comparative efficacy of two paclitaxel-coated balloons with different excipient coatings in patients with coronary in-stent restenosis: A pooled analysis of the Intracoronary Stenting and Angiographic Results: Optimizing Treatment of Drug Eluting St

scientific article published on 28 November 2017

Comparative prognostic value of postprocedural creatine kinase myocardial band and high-sensitivity troponin T in patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention

scientific article

Comparison of Delay Times Between Symptom Onset of an Acute ST-elevation Myocardial Infarction and Hospital Arrival in Men and Women <65 Years Versus ≥65 Years of Age.: Findings From the Multicenter Munich Examination of Delay in Patients Experienci

scientific article published on 18 September 2017

Comparison of prasugrel and bivalirudin vs clopidogrel and heparin in patients with ST-segment elevation myocardial infarction: Design and rationale of the Bavarian Reperfusion Alternatives Evaluation (BRAVE) 4 trial

scientific article published on 14 March 2014

Comparison of vascular closure devices vs manual compression after femoral artery puncture: the ISAR-CLOSURE randomized clinical trial

scientific article

Comprehensive endovascular treatment of multiple arterial emboli involving LIMA graft, distal aorta and upper and lower extremities in a patient with subacute cerebral hemorrhage

scientific article published on 10 November 2016

Correlates of poor outcome among patients with bleeding after coronary interventions.

scientific article

Cryoballoon vs. radiofrequency ablation for paroxysmal atrial fibrillation: an updated meta-analysis of randomized and observational studies

scientific article

Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia

scientific article

Detection of acute inflammatory myocarditis in Epstein Barr virus infection using hybrid 18F-fluoro-deoxyglucose-positron emission tomography/magnetic resonance imaging

scientific article published on September 2014

Development. ES cells to the rescue

scientific article

Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium

scientific article published on January 2017

Drug-Coated Balloons for Revascularization of Infrapopliteal Arteries: A Meta-Analysis of Randomized Trials

scientific article published on 18 April 2016

Drug-coated balloon angioplasty for in-stent restenosis of femoropopliteal arteries: a meta-analysis

scientific article

Drug-eluting versus bare-metal stents in saphenous vein graft lesions (ISAR-CABG): a randomised controlled superiority trial

scientific article

Dual-source RF transmission in cardiac SSFP imaging at 3 T: systematic spatial evaluation of image quality improvement compared to conventional RF transmission

scientific article

Effect of Erythropoietin in patients with acute myocardial infarction: five-year results of the REVIVAL-3 trial

scientific article

Embryonic heart progenitors and cardiogenesis

scientific article published on October 2013

Emergency treatment of decompensated aortic stenosis

scientific article published on 31 May 2017

Endothelial RAGE exacerbates acute postischaemic cardiac inflammation

scientific article published on 2 June 2016

Endovascular Treatment for Steno-Occlusive Iliac Artery Disease: Safety and Long-Term Outcome

scientific article

Erythropoietin in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomized, double-blind trial

scientific article published on 24 August 2010

Essential myosin light chain as a target for caspase-3 in failing myocardium

scientific article

Everolimus-eluting versus sirolimus-eluting stents: a meta-analysis of randomized trials

scientific article published on 26 July 2011

Expiration-Triggered Sinus Arrhythmia Predicts Outcome in Survivors of Acute Myocardial Infarction

scientific article published on May 2016

Extending human induced pluripotent stem cell technology to infectious diseases: new model for viral myocarditis

scientific article published in August 2014

Five-year clinical outcomes in patients with diabetes mellitus treated with polymer-free sirolimus- and probucol-eluting stents versus second-generation zotarolimus-eluting stents: a subgroup analysis of a randomized controlled trial

scientific article published on September 2016

Five-year follow-up of polymer-free sirolimus- and probucol-eluting stents versus new generation zotarolimus-eluting stents in patients presenting with st-elevation myocardial infarction

scientific article published on 05 July 2016

Five-year outcomes from a trial of three limus-eluting stents with different polymer coatings in patients with coronary artery disease: final results from the ISAR-TEST 4 randomised trial

scientific article

Force-interval relationship predicts mortality in survivors of myocardial infarction with atrial fibrillation

scientific article published on 6 January 2015

Functional comparison of induced pluripotent stem cell- and blood-derived GPIIbIIIa deficient platelets

scientific article

Gene transfer of the pancaspase inhibitor P35 reduces myocardial infarct size and improves cardiac function

scientific article published on 21 June 2005

Genetic risk of restenosis after percutaneous coronary interventions in the era of drug-eluting stents

scientific article

High on-treatment platelet reactivity and outcomes after percutaneous endovascular procedures in patients with peripheral artery disease

scientific article published on April 2016

High-Sensitivity Troponin T and Mortality After Elective Percutaneous Coronary Intervention.

scientific article published on November 2016

ISAR-PEBIS (Paclitaxel-Eluting Balloon Versus Conventional Balloon Angioplasty for In-Stent Restenosis of Superficial Femoral Artery): A Randomized Trial

scientific article

ISAR-REACT 3A: a study of reduced dose of unfractionated heparin in biomarker negative patients undergoing percutaneous coronary intervention

scientific article published on 30 August 2010

ISAR-SAFE: a randomized, double-blind, placebo-controlled trial of 6 vs. 12 months of clopidogrel therapy after drug-eluting stenting

scientific article published on 23 January 2015

Immature platelets as a novel biomarker for adverse cardiovascular events in patients after non-cardiac surgery

scientific article published on 10 August 2017

Impact of bivalirudin on post-procedural epicardial blood flow, risk of stent thrombosis and mortality after percutaneous coronary intervention

scientific article

Impact of coronary anatomy and stenting technique on long-term outcome after drug-eluting stent implantation for unprotected left main coronary artery disease.

scientific article published on 11 December 2013

Impact of immature platelets on platelet response to ticagrelor and prasugrel in patients with acute coronary syndrome

scientific article published on 27 July 2015

Impact of inhospital stent thrombosis and cerebrovascular accidents on long-term prognosis after percutaneous coronary intervention

scientific article published on 16 September 2014

Impact of stent size on angiographic and clinical outcomes after implantation of everolimus-eluting bioresorbable scaffolds in daily practice: insights from the ISAR-ABSORB registry

scientific article published on 17 June 2015

Impaired platelet function reduces myocardial infarct size in Galphaq knock-out mice in vivo

scientific article published on 12 October 2007

Inactivating mutations in NPC1L1 and protection from coronary heart disease

scientific article

Incidence and impact on prognosis of bleeding during percutaneous coronary interventions in patients with chronic kidney disease

scientific article published on 4 October 2013

Incidence and predictors of restenosis after coronary stenting in 10 004 patients with surveillance angiography

scientific article published on 22 November 2013

Incidence and prognostic value of bleeding after percutaneous coronary intervention in patients older than 75 years of age.

scientific article published on 19 October 2013

Increased bleeding risk during percutaneous coronary interventions by arterial hypertension

scientific article published on 3 November 2015

Induced pluripotent stem cell-derived cardiomyocytes: a versatile tool for arrhythmia research

scientific article published on March 2013

Induced pluripotent stem cells in cardiovascular research

scientific article published on January 2012

Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity.

scientific article

Intraindividual Comparison of Everolimus-Eluting Bioresorbable Vascular Scaffolds Versus Drug-Eluting Metallic Stents

scientific article

Islet1 cardiovascular progenitors: a single source for heart lineages?

scientific article published on January 2008

Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome

scientific article

Live fluorescent RNA-based detection of pluripotency gene expression in embryonic and induced pluripotent stem cells of different species

scientific article published in February 2015

Long-Term Clinical Outcomes of Patients Treated With Everolimus-Eluting Bioresorbable Stents in Routine Practice: 2-Year Results of the ISAR-ABSORB Registry

scientific article published on June 2017

Long-Term Efficacy and Safety of Paclitaxel-Eluting Balloon for the Treatment of Drug-Eluting Stent Restenosis: 3-Year Results of a Randomized Controlled Trial

scientific article published on 20 May 2015

Malabsorption of a Bioresorbable Vascular Scaffold System Leading to Very Late In-Scaffold Restenosis More Than 3.5 Years After Implantation: Assessment by Optical Coherence Tomography.

scientific article

Measurement of extracellular volume and transit time heterogeneity using contrast-enhanced myocardial perfusion MRI in patients after acute myocardial infarction

scientific article published on July 2016

MicroRNAs in a Cardiac Loop: Progenitor or Myocyte? ⬇️

scientific article published on December 14, 2010

Microvascular obstruction in patients with non-ST-elevation myocardial infarction: a contrast-enhanced cardiac magnetic resonance study.

scientific article

Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors

scientific article published on 12 May 2022

Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel

scientific article

Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors

scientific article published on 22 October 2009

Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification

scientific article

Mutational analysis of the human MESP1 gene in patients with congenital heart disease reveals a highly variable sequence in exon 1.

scientific article published on 19 September 2013

Negating the dominant-negative allele: a new treatment paradigm for arrhythmias explored in human induced pluripotent stem cell-derived cardiomyocytes

scientific article published on 12 April 2013

Neointimal Modification With Scoring Balloon and Efficacy of Drug-Coated Balloon Therapy in Patients With Restenosis in Drug-Eluting Coronary Stents: A Randomized Controlled Trial

scientific article

Obesity-associated hypertension is ameliorated in patients with TLR4 single nucleotide polymorphism (SNP) rs4986790.

scientific article

One-year outcomes with abciximab and unfractionated heparin versus bivalirudin during percutaneous coronary interventions in patients with non-ST-segment elevation myocardial infarction: updated results from the ISAR-REACT 4 trial

scientific article published on August 2013

Outcomes of patients treated with durable polymer platinum-chromium everolimus-eluting stents: a meta-analysis of randomised trials

scientific article published in October 2017

Paclitaxel- versus sirolimus-eluting stents for unprotected left main coronary artery disease.

scientific article published in May 2009

Paclitaxel-eluting balloons, paclitaxel-eluting stents, and balloon angioplasty in patients with restenosis after implantation of a drug-eluting stent (ISAR-DESIRE 3): a randomised, open-label trial

scientific article

Pluripotent stem cell models of human heart disease

scientific article

Polymer-free sirolimus- and probucol-eluting versus new generation zotarolimus-eluting stents in coronary artery disease: the Intracoronary Stenting and Angiographic Results: Test Efficacy of Sirolimus- and Probucol-Eluting versus Zotarolimus-elutin

scientific article published on 18 July 2011

Postextrasystolic blood pressure potentiation predicts poor outcome of cardiac patients

scientific article

Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages

scientific article

Prasugrel plus bivalirudin vs. clopidogrel plus heparin in patients with ST-segment elevation myocardial infarction

scientific article published on 09 May 2014

Predictors of antiplatelet response to prasugrel during maintenance treatment

scientific article published on 16 January 2014

Prognostic Value of Access and Non–Access Sites Bleeding After Percutaneous Coronary Intervention

scientific article published on 23 July 2013

Prognostic Value of High-sensitivity Troponin T After Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease

scientific article published on 24 May 2016

Prognostic role of restenosis in 10 004 patients undergoing routine control angiography after coronary stenting

scientific article published on 8 October 2014

Prognostic value of alkaline phosphatase in patients with acute coronary syndromes

scientific article published on June 2017

Prognostic value of bleeding after percutaneous coronary intervention in patients with diabetes

scientific article published in May 2014

Prognostic value of thyroid-stimulating hormone within reference range in patients with coronary artery disease

scientific article published on 18 July 2015

Prospective Evaluation of 18F-Fluorodeoxyglucose Uptake in Postischemic Myocardium by Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging as a Prognostic Marker of Functional Outcome

scientific article published on April 2016

Quantitative analysis of apoptotic markers in human end-stage heart failure

scientific article published in February 2008

Quantitative cardiovascular magnetic resonance: extracellular volume, native T1 and 18F-FDG PET/CMR imaging in patients after revascularized myocardial infarction and association with markers of myocardial damage and systemic inflammation.

scientific article

Radial artery applanation tonometry for continuous noninvasive arterial blood pressure monitoring in the cardiac intensive care unit

scientific article

Randomised comparison of vascular response to biodegradable polymer sirolimus eluting and permanent polymer everolimus eluting stents: An optical coherence tomography study

scientific article published in May 2018

Randomised, double-blind trial on the value of tapered discontinuation of clopidogrel maintenance therapy after drug-eluting stent implantation. Intracoronary Stenting and Antithrombotic Regimen: CAUTION in Discontinuing Clopidogrel Therapy--ISAR-CA

scientific article

Randomized Comparison of Paclitaxel-Eluting Balloon and Stenting Versus Plain Balloon Plus Stenting Versus Directional Atherectomy for Femoral Artery Disease (ISAR-STATH).

scientific article published on 19 April 2017

Randomized comparison of ticagrelor versus prasugrel in patients with acute coronary syndrome and planned invasive strategy--design and rationale of the iNtracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment (IS

scientific article published on 27 December 2013

Randomized trial of paclitaxel- versus sirolimus-eluting stents for treatment of coronary restenosis in sirolimus-eluting stents: the ISAR-DESIRE 2 (Intracoronary Stenting and Angiographic Results: Drug Eluting Stents for In-Stent Restenosis 2) stud

scientific article published on 11 March 2010

Randomized, non-inferiority trial of three limus agent-eluting stents with different polymer coatings: the Intracoronary Stenting and Angiographic Results: Test Efficacy of 3 Limus-Eluting Stents (ISAR-TEST-4) Trial

scientific article published on 30 August 2009

Rationale and design of a randomised clinical trial comparing vascular closure device and manual compression to achieve haemostasis after diagnostic coronary angiography: the Instrumental Sealing of ARterial puncture site - CLOSURE device versus man

scientific article published on June 2014

Recapitulating long-QT syndrome using induced pluripotent stem cell technology

scientific article published on 13 March 2012

Relation of Gamma-Glutamyl Transferase to Cardiovascular Events in Patients With Acute Coronary Syndromes

scientific article published on 17 February 2016

Renal failure after renal sympathetic ablation in a patient with chronic kidney disease — Which came first, the chicken or the egg? ⬇️

scientific article published on May 4, 2013

Reply

Reply: Duration of Triple Therapy in Patients Requiring Oral Anticoagulation After Drug-Eluting Stent Implantation

scientific article published in September 2015

Reply: Duration of Triple Therapy: A Clinical Question Yet to Be Answered

scientific article published in November 2015

Response to Letter Regarding Article, “Validation of the Bleeding Academic Research Consortium Definition of Bleeding in Patients With Coronary Artery Disease Undergoing Percutaneous Coronary Intervention”

scholarly article by Gjin Ndrepepa et al published 23 October 2012 in Circulation

Retroviral infection and selection of culture-derived platelets allows study of the effect of transgenes on platelet physiology ex vivo and on thrombus formation in vivo

scientific article published on 2 June 2005

Right ventricular fistula post-TAVR: amenable to interventional closure treatment

scientific article

Risk of stent thrombosis among bare-metal stents, first-generation drug-eluting stents, and second-generation drug-eluting stents: results from a registry of 18,334 patients

scientific article published in December 2013

Safety and efficacy of a potential treatment algorithm by using manual compression repair and ultrasound-guided thrombin injection for the management of iatrogenic femoral artery pseudoaneurysm in a large patient cohort

scientific article published in April 2014

Safety and efficacy of different stent types for the endovascular therapy of extracranial vertebral artery disease

scientific article

Selective attenuation of norepinephrine release and stress-induced heart rate increase by partial adenosine A1 agonism

scientific article (publication date: 28 March 2011)

Sex differences in the non-invasive risk stratification and prognosis after myocardial infarction.

scientific article published on 12 August 2014

Simultaneous positron emission tomography/magnetic resonance imaging identifies sustained regional abnormalities in cardiac metabolism and function in stress-induced transient midventricular ballooning syndrome: a variant of Takotsubo cardiomyopathy

scientific article published in November 2012

Sirolimus-eluting versus paclitaxel-eluting stents in diabetic and non-diabetic patients within sirolimus-eluting stent restenosis: results from the ISAR-DESIRE 2 trial

scientific article published on 15 February 2014

Six Versus Twelve Months Clopidogrel Therapy After Drug-Eluting Stenting in Patients With Acute Coronary Syndrome: An ISAR-SAFE Study Subgroup Analysis

scientific article published on 14 September 2016

Steerable induction of the Thymosin ß4/MRTF-A pathway via AAV-based overexpression induces therapeutic neovascularization

scientific article

Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes

scientific article published in January 2017

Suppression of Arrhythmia by Enhancing Mitochondrial Ca2+ Uptake in Catecholaminergic Ventricular Tachycardia Models

scientific article

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

scientific article published on February 2017

The impact of therapeutic hypothermia on on-treatment platelet reactivity and clinical outcome in cardiogenic shock patients undergoing primary PCI for acute myocardial infarction: Results from the ISAR-SHOCK registry

scientific article published on 30 April 2015

The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway

scientific article published on 14 June 2007

Three-year efficacy and safety of new- versus early-generation drug-eluting stents for unprotected left main coronary artery disease insights from the ISAR-LEFT MAIN and ISAR-LEFT MAIN 2 trials

scientific article published on 22 December 2015

Thymosin β4 Improves Differentiation and Vascularization of EHTs

scientific article

Ticagrelor versus prasugrel in patients with high on-clopidogrel treatment platelet reactivity after PCI: The ISAR-ADAPT-PF study

scientific article published on 8 June 2016

Time does not heal all wounds: very late stent thrombosis eight years after implantation of a sirolimus-eluting stent due to positive remodelling, saccular evaginations and marked vascular inflammation

scientific article published on July 1, 2013

Transcatheter aortic-valve endocarditis confirmed by transesophageal echocardiography

scientific article published in January 2013

Treatment of acute left main occlusion by early revascularization combined with extracorporeal circulation achieves substantial myocardial salvage as assessed by simultaneous positron emission tomography/magnetic resonance imaging

scientific article published on 15 July 2014

Vascular response to percutaneous coronary intervention with biodegradable-polymer vs. new-generation durable-polymer drug-eluting stents: a meta-analysis of optical coherence tomography imaging trials

scientific article published on 2 January 2018

Very late stent thrombosis 42 months after implantation of sirolimus-eluting stent and discontinuation of antiplatelet therapy

scientific article published on 25 March 2009

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