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List of works by Ursula Rinas

A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs

scientific article published on 8 February 2013

Analysis and Design of Stimulus Response Curves of E. coli

scientific article published on 12 November 2012

Application of an SPR-based receptor assay for the determination of biologically active recombinant bone morphogenetic protein-2.

scientific article published on 3 March 2005

Assessing stability and assembly of the hepatitis B surface antigen into virus-like particles during down-stream processing

scientific article published on 12 June 2015

Bacterial Inclusion Bodies: Discovering Their Better Half

scientific article published on 26 February 2017

Bacterial inclusion bodies are industrially exploitable amyloids

scientific article published in 2018

Biphasic modulation of Wnt signaling supports efficient foregut endoderm formation from human pluripotent stem cells

scientific article

Change of extracellular cAMP concentration is a sensitive reporter for bacterial fitness in high-cell-density cultures of Escherichia coli

scientific article published in September 2004

Characterization of recombinant factor XIIIa produced in Saccharomyces cerevisiae

scientific article published on 01 June 1990

Conformational and functional variants of CD44-targeted protein nanoparticles bio-produced in bacteria

scientific article published on 14 April 2016

Cultivation of recombinant E. coli and production of fusion protein in 60-1 bubble column and airlift tower loop reactors

scientific article published on July 1, 1991

Decrease of UPR- and ERAD-related proteins in Pichia pastoris during methanol-induced secretory insulin precursor production in controlled fed-batch cultures

scientific article published on 13 February 2014

Dengue-specific subviral nanoparticles: design, creation and characterization

scientific article published on 25 May 2013

Expression and purification of bioactive soluble murine stem cell factor from recombinant Escherichia coli using thioredoxin as fusion partner

scientific article published on 22 January 2011

Expression of intracellular hemoglobin improves protein synthesis in oxygen-limited Escherichia coli

scientific article published on September 1, 1990

Fate of the UPR marker protein Kar2/Bip and autophagic processes in fed-batch cultures of secretory insulin precursor producing Pichia pastoris

article

Folding and dimerization kinetics of bone morphogenetic protein-2, a member of the transforming growth factor-β family

scientific article published on 22 November 2012

Global proteome response of Escherichia coli BL21 to production of human basic fibroblast growth factor in complex and defined medium

scientific article published on 20 June 2017

Heparin: role in protein purification and substitution with animal-component free material

scientific article published in 2018

Improving protein delivery of fibroblast growth factor-2 from bacterial inclusion bodies used as cell culture substrates

scientific article published on 19 December 2013

In situ multi-wavelength fluorescence spectroscopy as effective tool to simultaneously monitor spore germination, metabolic activity and quantitative protein production in recombinant Aspergillus niger fed-batch cultures

scientific article

In-depth analysis of the Aspergillus niger glucoamylase (glaA) promoter performance using high-throughput screening and controlled bioreactor cultivation techniques

scientific article published on 22 May 2008

Inclusion bodies of fuculose-1-phosphate aldolase as stable and reusable biocatalysts.

scientific article

Inclusion body anatomy and functioning of chaperone-mediated in vivo inclusion body disassembly during high-level recombinant protein production in Escherichia coli

scientific article

Is energy excess the initial trigger of carbon overflow metabolism? Transcriptional network response of carbon-limited Escherichia coli to transient carbon excess

scientific article published on 21 April 2022

Kinetics control preferential heterodimer formation of platelet-derived growth factor from unfolded A- and B-chains

scientific article

Metabolic adaptation of Escherichia coli during temperature-induced recombinant protein production: 1. Readjustment of metabolic enzyme synthesis

scientific article published in November 2002

Metabolic adaptation of Escherichia coli during temperature-induced recombinant protein production: 2. Redirection of metabolic fluxes

scientific article published in November 2002

Metabolic costs of amino acid and protein production in Escherichia coli

scientific article published on 15 July 2013

Metabolic flux analysis of Escherichia coli in glucose-limited continuous culture. I. Growth-rate-dependent metabolic efficiency at steady state

scientific article

Metabolic flux analysis of Escherichia coli in glucose-limited continuous culture. II. Dynamic response to famine and feast, activation of the methylglyoxal pathway and oscillatory behaviour

scientific article

Metabolic peculiarities of Aspergillus niger disclosed by comparative metabolic genomics

scientific article

More than just a metabolic regulator--elucidation and validation of new targets of PdhR in Escherichia coli

scientific article

On-line determination of intracellular beta-galactosidase activity in recombinant Escherichia coli using flow injection analysis (FIA)

scientific article published on August 1, 1991

Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress

scientific article published on 20 January 2014

Optimized procedure for renaturation of recombinant human bone morphogenetic protein-2 at high protein concentration

scientific article published in March 2004

Optimized procedure to generate heavy isotope and selenomethionine-labeled proteins for structure determination using Escherichia coli-based expression systems

scientific article

Packaging protein drugs as bacterial inclusion bodies for therapeutic applications

scientific article published on 11 June 2012

Physiological response of Pichia pastoris GS115 to methanol-induced high level production of the Hepatitis B surface antigen: catabolic adaptation, stress responses, and autophagic processes

scientific article published on 8 August 2012

Preparation of bioactive soluble human leukemia inhibitory factor from recombinant Escherichia coli using thioredoxin as fusion partner

scientific article published on 8 April 2010

Protein compositional analysis of inclusion bodies produced in recombinant Escherichia coli

scientific article published on August 1, 1992

Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview

scientific article published on 4 April 2008

Proteolytic response to the expression of an abnormal beta-galactosidase in Escherichia coli

scientific article published on June 1, 1992

Purification of bone morphogenetic protein-2 from refolding mixtures using mixed-mode membrane chromatography

scientific article published on 20 August 2016

Purification of hepatitis B surface antigen virus-like particles from recombinant Pichia pastoris and in vivo analysis of their immunogenic properties

scientific article published on 27 September 2013

Recombinant protein production associated growth inhibition results mainly from transcription and not from translation

scientific article published on 06 April 2020

Recombinant protein production associated metabolic burden reflects anabolic constraints and reveals similarities to a carbon overfeeding response

scientific article published on 03 September 2020

Renaturation and purification of bone morphogenetic protein-2 produced as inclusion bodies in high-cell-density cultures of recombinant Escherichia coli.

scientific article

Response of fluxome and metabolome to temperature-induced recombinant protein synthesis in Escherichia coli

scientific article published on 10 July 2007

Roles of heat-shock chaperones in the production of recombinant proteins in Escherichia coli.

scientific article published in January 2004

Selective leakage of host-cell proteins during high-cell-density cultivation of recombinant and non-recombinant Escherichia coli

scientific article published in May 2004

Side effects of chaperone gene co-expression in recombinant protein production

scientific article

Simple defined autoinduction medium for high-level recombinant protein production using T7-based Escherichia coli expression systems.

scientific article

Simple high-cell density fed-batch technique for high-level recombinant protein production with Pichia pastoris: Application to intracellular production of Hepatitis B surface antigen

scientific article published on 10 February 2009

Simulation of cell growth, substrate consumption and product formation with recombinant Escherichia coli

scientific article published on May 1, 1991

Smart sustainable bottle (SSB) system for E. coli based recombinant protein production

scientific article

Solubilization and renaturation of biologically active human bone morphogenetic protein-4 from inclusion bodies.

scientific article published on 4 April 2018

Strategies for the recovery of active proteins through refolding of bacterial inclusion body proteins

scientific article

Stress induced by recombinant protein production in Escherichia coli

scientific article published in January 2004

Structured model for cell growth and enzyme production by recombinant Escherichia coli

scientific article published on May 1, 1991

Susceptibility towards intramolecular disulphide-bond formation affects conformational stability and folding of human basic fibroblast growth factor

scientific article published on October 15, 1998

Systems-Level Analysis of Protein Quality in Inclusion Body-Forming Escherichia coli Cells

scholarly article published 2009

The intra- and extracellular proteome of Aspergillus niger growing on defined medium with xylose or maltose as carbon substrate

scientific article published on 20 April 2010

The metabolic potential of Escherichia coli BL21 in defined and rich medium

scientific article published on 23 March 2014

Virus-like particle production with yeast: ultrastructural and immunocytochemical insights into Pichia pastoris producing high levels of the hepatitis B surface antigen

scientific article