List of works - Patrice G Guyenet

A group of glutamatergic interneurons expressing high levels of both neurokinin-1 receptors and somatostatin identifies the region of the pre-Bötzinger complex

scientific article

Acid sensitivity and ultrastructure of the retrotrapezoid nucleus in Phox2b-EGFP transgenic mice

scientific article

Activation of 5-hydroxytryptamine type 3 receptor-expressing C-fiber vagal afferents inhibits retrotrapezoid nucleus chemoreceptors in rats

scientific article

Activation of the retrotrapezoid nucleus by posterior hypothalamic stimulation

scientific article

Afferent and efferent connections of C1 cells with spinal cord or hypothalamic projections in mice

scientific article

Afferent and efferent connections of the rat retrotrapezoid nucleus

scientific article

Anesthetic activation of central respiratory chemoreceptor neurons involves inhibition of a THIK-1-like background K(+) current

scientific article

Authors' response to G. B. Richerson's commentary

Baro-activated neurons with pulse-modulated activity in the rat caudal ventrolateral medulla express GAD67 mRNA.

scientific article

Blood Pressure Regulation by the Rostral Ventrolateral Medulla in Conscious Rats: Effects of Hypoxia, Hypercapnia, Baroreceptor Denervation, and Anesthesia

scientific article

C1 neurons mediate a stress-induced anti-inflammatory reflex in mice

scientific article

C1 neurons: a nodal point for stress?

scientific article published on 27 October 2017

C1 neurons: the body's EMTs

scientific article

Cardiorespiratory neurons of the rat ventrolateral medulla contain TASK-1 and TASK-3 channel mRNA.

scientific article

Cardiovascular Deficits After Lesions of C1 Adrenergic Neurons With a Saporin-Based Immunotoxin

Central CO2 chemoreception and integrated neural mechanisms of cardiovascular and respiratory control

scientific article

Central Network Dynamics Regulating Visceral and Humoral Functions

scientific article published in November 2017

Central chemoreceptors and sympathetic vasomotor outflow

scientific article

Central respiratory chemoreception

scientific article

Chapter 8 Role of medulla oblongata in generation of sympathetic and vagal outflows

Chemoreception and asphyxia-induced arousal

scientific article

Cholinergic neurons in the mouse rostral ventrolateral medulla target sensory afferent areas

scientific article

Coexpression of vesicular glutamate transporter-3 and gamma-aminobutyric acidergic markers in rat rostral medullary raphe and intermediolateral cell column

scientific article

Control of breathing by raphe obscurus serotonergic neurons in mice

scientific article

Decompensated hemorrhage activates serotonergic neurons in the subependymal parapyramidal region of the rat medulla

scientific article

Depressor and tachypneic responses to chemical stimulation of the ventral respiratory group are reduced by ablation of neurokinin-1 receptor-expressing neurons.

scientific article

Detection of amino acid and peptide transmitters in physiologically identified brainstem cardiorespiratory neurons

scientific article

Fos expression by glutamatergic neurons of the solitary tract nucleus after phenylephrine-induced hypertension in rats

scientific article

GABAergic and glycinergic presympathetic neurons of rat medulla oblongata identified by retrograde transport of pseudorabies virus and in situ hybridization

scientific article

GABAergic pump cells of solitary tract nucleus innervate retrotrapezoid nucleus chemoreceptors

scientific article

Galanin is a selective marker of the retrotrapezoid nucleus in rats

scientific article

Glutamatergic neuronal projections from the marginal layer of the rostral ventral medulla to the respiratory centers in rats

scientific article

Glutamatergic neurotransmission between the C1 neurons and the parasympathetic preganglionic neurons of the dorsal motor nucleus of the vagus

scientific article

How does CO2 activate the neurons of the retrotrapezoid nucleus?

scientific article

Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2.

scientific article

Hypoxia silences retrotrapezoid nucleus respiratory chemoreceptors via alkalosis

scientific article

Inhibitory input from slowly adapting lung stretch receptors to retrotrapezoid nucleus chemoreceptors

scientific article

Inspiratory augmenting bulbospinal neurons express both glutamatergic and enkephalinergic phenotypes

scientific article

Is plasticity within the retrotrapezoid nucleus responsible for the recovery of the PCO2 set-point after carotid body denervation in rats?

scientific article

Location and properties of respiratory neurones with putative intrinsic bursting properties in the rat in situ

scientific article published on 5 May 2009

Loss of brainstem serotonergic neurons impairs autoresuscitation in neonate rats: is this relevant to the sudden infant death syndrome? ⬇️

scientific article published on November 15, 2011

Monosynaptic glutamatergic activation of locus coeruleus and other lower brainstem noradrenergic neurons by the C1 cells in mice

scientific article

Neural Control of Breathing and CO2 Homeostasis

scientific article

Neurokinin-1 receptor-expressing cells of the ventral respiratory group are functionally heterogeneous and predominantly glutamatergic.

scientific article

Neurokinin-1 receptor-expressing cells regulate depressor region of rat ventrolateral medulla

scientific article

Nonradioactive In Situ Hybridization in Combination with Tract-Tracing

Novel two-rhythm generator theory of breathing in mammals

scientific article

Opioid signalling in the rat rostral ventrolateral medulla

scientific article

Optogenetic stimulation of adrenergic C1 neurons causes sleep state-dependent cardiorespiratory stimulation and arousal with sighs in rats

scientific article

Optogenetic stimulation of c1 and retrotrapezoid nucleus neurons causes sleep state-dependent cardiorespiratory stimulation and arousal in rats

scientific article

Orexin A activates retrotrapezoid neurons in mice

scientific article

PHYSIOLOGY. Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons

scientific article

Peripheral chemoreceptor inputs to retrotrapezoid nucleus (RTN) CO2-sensitive neurons in rats

scientific article

Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats

scientific article

Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats

scientific article

Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats

scientific article

Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats

scientific article

Phox2b-expressing retrotrapezoid neurons are intrinsically responsive to H+ and CO2.

scientific article

Pre-Bötzinger complex receives glutamatergic innervation from galaninergic and other retrotrapezoid nucleus neurons

scientific article

Proton detection and breathing regulation by the retrotrapezoid nucleus

scientific article

Putative Mechanism of Salt-Dependent Neurogenic Hypertension: Cell-Autonomous Activation of Organum Vasculosum Laminae Terminalis Neurons by Hypernatremia

scientific article published on 28 November 2016

Re: Homing in on the specific phenotype(s) of central respiratory chemoreceptors

Regulation of breathing and autonomic outflows by chemoreceptors

scientific article

Regulation of visceral sympathetic tone by A5 noradrenergic neurons in rodents

scientific article

Respiratory control by ventral surface chemoreceptor neurons in rats

scientific article

Retrotrapezoid nucleus and central chemoreception

scientific article

Retrotrapezoid nucleus and parafacial respiratory group

scientific article

Retrotrapezoid nucleus, respiratory chemosensitivity and breathing automaticity

scientific article

Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors

scientific article

Rostral Ventrolateral Medulla and Hypertension

scientific article published on 01 September 2018

Sciatic nerve stimulation activates the retrotrapezoid nucleus in anesthetized rats

scientific article

Selective lesion of retrotrapezoid Phox2b-expressing neurons raises the apnoeic threshold in rats

scientific article

Selective optogenetic activation of rostral ventrolateral medullary catecholaminergic neurons produces cardiorespiratory stimulation in conscious mice

scientific article

Selective optogenetic stimulation of the retrotrapezoid nucleus in sleeping rats activates breathing without changing blood pressure or causing arousal or sighs

scientific article

Serotonergic raphe neurons express TASK channel transcripts and a TASK-like pH- and halothane-sensitive K+ conductance.

scientific article

State-dependent control of breathing by the retrotrapezoid nucleus

scientific article

TASK-2 channels contribute to pH sensitivity of retrotrapezoid nucleus chemoreceptor neurons

scientific article

The 2008 Carl Ludwig Lecture: retrotrapezoid nucleus, CO2 homeostasis, and breathing automaticity

scientific article

The Presympathetic Cells of the Rostral Ventrolateral Medulla (RVLM): Anatomy, Physiology and Role in the Control of Circulation

scholarly article published 2004

The Retrotrapezoid Nucleus and Central Chemoreception

The baroreflex and beyond: control of sympathetic vasomotor tone by GABAergic neurons in the ventrolateral medulla

scientific article

The orexinergic neurons receive synaptic input from C1 cells in rats.

scientific article

The respiratory chemoreception conundrum: light at the end of the tunnel?

scientific article

The retrotrapezoid nucleus and breathing

scientific article

The retrotrapezoid nucleus and central chemoreception

scientific article

The retrotrapezoid nucleus stimulates breathing by releasing glutamate in adult conscious mice

scientific article

The role of pH-sensitive TASK channels in central respiratory chemoreception

scientific article

The sympathetic control of blood pressure

scientific article

Transneuronal mapping of the CNS network controlling sympathetic outflow to the rat thymus

scientific article

Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+ splenocytes.

scientific article

Vesicular glutamate transporter 2 is required for the respiratory and parasympathetic activation produced by optogenetic stimulation of catecholaminergic neurons in the rostral ventrolateral medulla of mice in vivo

scientific article

Vesicular glutamate transporter DNPI/VGLUT2 is expressed by both C1 adrenergic and nonaminergic presympathetic vasomotor neurons of the rat medulla

scientific article

Vesicular glutamate transporter DNPI/VGLUT2 mRNA is present in C1 and several other groups of brainstem catecholaminergic neurons

scientific article

Water deprivation activates a glutamatergic projection from the hypothalamic paraventricular nucleus to the rostral ventrolateral medulla

scientific article

Wild-type microglia arrest pathology in a mouse model of Rett syndrome ⬇️

scientific article published on March 18, 2012

List of works by Patrice G Guyenet

A group of glutamatergic interneurons expressing high levels of both neurokinin-1 receptors and somatostatin identifies the region of the pre-Bötzinger complex

Acid sensitivity and ultrastructure of the retrotrapezoid nucleus in Phox2b-EGFP transgenic mice

Activation of 5-hydroxytryptamine type 3 receptor-expressing C-fiber vagal afferents inhibits retrotrapezoid nucleus chemoreceptors in rats

Activation of the retrotrapezoid nucleus by posterior hypothalamic stimulation

Afferent and efferent connections of C1 cells with spinal cord or hypothalamic projections in mice

Afferent and efferent connections of the rat retrotrapezoid nucleus

Anesthetic activation of central respiratory chemoreceptor neurons involves inhibition of a THIK-1-like background K(+) current

Authors' response to G. B. Richerson's commentary

Baro-activated neurons with pulse-modulated activity in the rat caudal ventrolateral medulla express GAD67 mRNA.

Blood Pressure Regulation by the Rostral Ventrolateral Medulla in Conscious Rats: Effects of Hypoxia, Hypercapnia, Baroreceptor Denervation, and Anesthesia

C1 neurons mediate a stress-induced anti-inflammatory reflex in mice

C1 neurons: a nodal point for stress?

C1 neurons: the body's EMTs

Cardiorespiratory neurons of the rat ventrolateral medulla contain TASK-1 and TASK-3 channel mRNA.

Cardiovascular Deficits After Lesions of C1 Adrenergic Neurons With a Saporin-Based Immunotoxin

Central CO2 chemoreception and integrated neural mechanisms of cardiovascular and respiratory control

Central Network Dynamics Regulating Visceral and Humoral Functions

Central chemoreceptors and sympathetic vasomotor outflow

Central respiratory chemoreception

Chapter 8 Role of medulla oblongata in generation of sympathetic and vagal outflows

Chemoreception and asphyxia-induced arousal

Cholinergic neurons in the mouse rostral ventrolateral medulla target sensory afferent areas

Coexpression of vesicular glutamate transporter-3 and gamma-aminobutyric acidergic markers in rat rostral medullary raphe and intermediolateral cell column

Control of breathing by raphe obscurus serotonergic neurons in mice

Decompensated hemorrhage activates serotonergic neurons in the subependymal parapyramidal region of the rat medulla

Depressor and tachypneic responses to chemical stimulation of the ventral respiratory group are reduced by ablation of neurokinin-1 receptor-expressing neurons.

Detection of amino acid and peptide transmitters in physiologically identified brainstem cardiorespiratory neurons

Fos expression by glutamatergic neurons of the solitary tract nucleus after phenylephrine-induced hypertension in rats

GABAergic and glycinergic presympathetic neurons of rat medulla oblongata identified by retrograde transport of pseudorabies virus and in situ hybridization

GABAergic pump cells of solitary tract nucleus innervate retrotrapezoid nucleus chemoreceptors

Galanin is a selective marker of the retrotrapezoid nucleus in rats

Glutamatergic neuronal projections from the marginal layer of the rostral ventral medulla to the respiratory centers in rats

Glutamatergic neurotransmission between the C1 neurons and the parasympathetic preganglionic neurons of the dorsal motor nucleus of the vagus

How does CO2 activate the neurons of the retrotrapezoid nucleus?

Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2.

Hypoxia silences retrotrapezoid nucleus respiratory chemoreceptors via alkalosis

Inhibitory input from slowly adapting lung stretch receptors to retrotrapezoid nucleus chemoreceptors

Inspiratory augmenting bulbospinal neurons express both glutamatergic and enkephalinergic phenotypes

Is plasticity within the retrotrapezoid nucleus responsible for the recovery of the PCO2 set-point after carotid body denervation in rats?

Location and properties of respiratory neurones with putative intrinsic bursting properties in the rat in situ

Loss of brainstem serotonergic neurons impairs autoresuscitation in neonate rats: is this relevant to the sudden infant death syndrome? ⬇️

Monosynaptic glutamatergic activation of locus coeruleus and other lower brainstem noradrenergic neurons by the C1 cells in mice

Neural Control of Breathing and CO2 Homeostasis

Neurokinin-1 receptor-expressing cells of the ventral respiratory group are functionally heterogeneous and predominantly glutamatergic.

Neurokinin-1 receptor-expressing cells regulate depressor region of rat ventrolateral medulla

Nonradioactive In Situ Hybridization in Combination with Tract-Tracing

Novel two-rhythm generator theory of breathing in mammals

Opioid signalling in the rat rostral ventrolateral medulla

Optogenetic stimulation of adrenergic C1 neurons causes sleep state-dependent cardiorespiratory stimulation and arousal with sighs in rats

Optogenetic stimulation of c1 and retrotrapezoid nucleus neurons causes sleep state-dependent cardiorespiratory stimulation and arousal in rats

Orexin A activates retrotrapezoid neurons in mice

PHYSIOLOGY. Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons

Peripheral chemoreceptor inputs to retrotrapezoid nucleus (RTN) CO2-sensitive neurons in rats

Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats

Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats

Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats

Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats

Phox2b-expressing retrotrapezoid neurons are intrinsically responsive to H+ and CO2.

Pre-Bötzinger complex receives glutamatergic innervation from galaninergic and other retrotrapezoid nucleus neurons

Proton detection and breathing regulation by the retrotrapezoid nucleus

Putative Mechanism of Salt-Dependent Neurogenic Hypertension: Cell-Autonomous Activation of Organum Vasculosum Laminae Terminalis Neurons by Hypernatremia

Re: Homing in on the specific phenotype(s) of central respiratory chemoreceptors

Regulation of breathing and autonomic outflows by chemoreceptors

Regulation of visceral sympathetic tone by A5 noradrenergic neurons in rodents

Respiratory control by ventral surface chemoreceptor neurons in rats

Retrotrapezoid nucleus and central chemoreception

Retrotrapezoid nucleus and parafacial respiratory group

Retrotrapezoid nucleus, respiratory chemosensitivity and breathing automaticity

Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors

Rostral Ventrolateral Medulla and Hypertension

Sciatic nerve stimulation activates the retrotrapezoid nucleus in anesthetized rats

Selective lesion of retrotrapezoid Phox2b-expressing neurons raises the apnoeic threshold in rats

Selective optogenetic activation of rostral ventrolateral medullary catecholaminergic neurons produces cardiorespiratory stimulation in conscious mice

Selective optogenetic stimulation of the retrotrapezoid nucleus in sleeping rats activates breathing without changing blood pressure or causing arousal or sighs

Serotonergic raphe neurons express TASK channel transcripts and a TASK-like pH- and halothane-sensitive K+ conductance.

State-dependent control of breathing by the retrotrapezoid nucleus

TASK-2 channels contribute to pH sensitivity of retrotrapezoid nucleus chemoreceptor neurons

The 2008 Carl Ludwig Lecture: retrotrapezoid nucleus, CO2 homeostasis, and breathing automaticity

The Presympathetic Cells of the Rostral Ventrolateral Medulla (RVLM): Anatomy, Physiology and Role in the Control of Circulation