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List of works by Theresa A Guise

A "Connexin" Responsible for the Fatal Attraction of Cancer to Bone

A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases

scientific article

Actions of bisphosphonates in animal models of breast cancer

scientific article

Ad5/48 hexon oncolytic virus expressing sTGFβRIIFc produces reduced hepatic and systemic toxicities and inhibits prostate cancer bone metastases

scientific article published on 5 May 2014

Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis

scientific article

Advances in treating metastatic bone cancer: summary statement for the First Cambridge Conference

scientific article

Advancing treatment for metastatic bone cancer: consensus recommendations from the Second Cambridge Conference

scientific article

Agents targeting prostate cancer bone metastasis

scientific article published on December 2009

Alkaline phosphatase in metastatic castration-resistant prostate cancer: reassessment of an older biomarker

scientific article published on 21 June 2018

Anti-placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation

scientific article published on 3 August 2010

Antitumor effects of bisphosphonates: promising preclinical evidence

scientific article

Aromatase inhibitor-induced bone loss increases the progression of estrogen receptor-negative breast cancer in bone and exacerbates muscle weakness in vivo

scientific article

Assessing new bone formation in neonatal calvarial organ cultures

scientific article

BMP7: a new bone metastases prevention?

scientific article

Basic mechanisms responsible for osteolytic and osteoblastic bone metastases

scientific article

Bisphosphonate-Associated Osteonecrosis of the Jaw: Report of a Task Force of the American Society for Bone and Mineral Research

article

Bone health effects of androgen-deprivation therapy and androgen receptor inhibitors in patients with nonmetastatic castration-resistant prostate cancer

scientific article published on 07 October 2020

Bone loss and fracture risk associated with cancer therapy

scientific article

Bone-Induced Expression of Integrin β3 Enables Targeted Nanotherapy of Breast Cancer Metastases

scientific article published on 30 August 2017

Breaking Down Barriers to Chemoresistance: Role of Chemotherapy-Induced Osteoblastic Jagged1.

scientific article published in December 2017

Breaking down bone: new insight into site-specific mechanisms of breast cancer osteolysis mediated by metalloproteinases

scientific article published on September 2009

Breaking new ground to build bone

scientific article

Breast Cancer Bone Metastases: It’s All about the Neighborhood ⬇️

scientific article published on August 29, 2013

Breast cancer metastasis to bone: mechanisms of osteolysis and implications for therapy

scientific article

Cancer to bone: a fatal attraction ⬇️

scientific article published on May 19, 2011

Cancer treatment-related bone disease

scientific article

Cancer-Associated Osteoclast Differentiation Takes a Good Look in the miR(NA)ror ⬇️

scientific article published on October 14, 2013

Cancer-associated bone disease

scientific article

Cancer-associated muscle weakness: What's bone got to do with it?

scientific article published on 20 May 2015

Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity

scientific article published on 01 June 2019

Corrigendum: Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin

scientific article published on June 2015

Curcuminoids Block TGF-β Signaling in Human Breast Cancer Cells and Limit Osteolysis in a Murine Model of Breast Cancer Bone Metastasis ⬇️

scientific article published on November 12, 2012

Decreased Autocrine EGFR Signaling in Metastatic Breast Cancer Cells Inhibits Tumor Growth in Bone and Mammary Fat Pad ⬇️

scientific article published on January 19, 2012

Development of oncolytic adenovirus armed with a fusion of soluble transforming growth factor-beta receptor II and human immunoglobulin Fc for breast cancer therapy

scientific article published on November 2006

Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formation

scientific article

Differential Bone Loss in Mouse Models of Colon Cancer Cachexia

scientific article

Differential stem- and progenitor-cell trafficking by prostaglandin E2.

scientific article published on 13 March 2013

Do markers of bone turnover predict clinical outcome in patients with bone metastases?

scientific article

Does prostate-specific antigen contribute to bone metastases?

scientific article

Drug insight: the use of bisphosphonates for the prevention and treatment of osteoporosis in men.

scientific article

Dystrophic spinal deformities in a neurofibromatosis type 1 murine model

scientific article

Endothelins in bone cancer metastases

scientific article

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

scientific article published on 30 March 2010

Erratum to: Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

scholarly article published in Breast Cancer Research and Treatment

Estrogenic side effects of androgen deprivation therapy.

scientific article

Examining the Metastatic Niche: Targeting the Microenvironment ⬇️

scientific article published on October 1, 2010

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

scientific article

GLI2-mediated melanoma invasion and metastasis

scientific article

Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo

scientific article

Guide to bone health and disease in cystic fibrosis

scientific article

Halofuginone inhibits TGF-β/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis

scientific article published on 23 September 2017

Halofuginone inhibits the establishment and progression of melanoma bone metastases

scientific article

Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis

scientific article

Hyperactive Transforming Growth Factor-β1 Signaling Potentiates Skeletal Defects in a Neurofibromatosis Type 1 Mouse Model ⬇️

scientific article published on December 1, 2013

Hypercalcemia of Malignancy: A New Twist on an Old Problem

scientific article published on 01 May 2016

Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment

scientific article

Increased S1P expression in osteoclasts enhances bone formation in an animal model of Paget's disease

scientific article published on 27 October 2020

Local effects of malignancy on bone

scientific article

Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cell, Leading to Bohring-Opitz-like Syndrome in Mice

scientific article published on 24 May 2016

LyP-1-modified oncolytic adenoviruses targeting transforming growth factor β inhibit tumor growth and metastases and augment immune checkpoint inhibitor therapy in breast cancer mouse models

scientific article published on 12 May 2020

Measles virus nucleocapsid protein increases osteoblast differentiation in Paget's disease

scientific article published on 15 February 2016

Mechanisms and treatment for bone metastases.

scientific article

Mechanisms of Osteoblastic Metastases: Role of Endothelin-1 ⬇️

scientific article published on October 1, 2003

Modulation of mammalian life span by the short isoform of p53.

scientific article

Molecular Mechanisms of Bone Metastasis and Therapeutic Implications ⬇️

scientific article published on October 1, 2003

Molecular biology and therapeutics in musculoskeletal oncology

scientific article

Molecular biology of bone metastasis

scientific article

Molecular mechanisms and treatment of bone metastasis

scientific article

Molecular mechanisms of bone metastasis and associated muscle weakness

scientific article

Molecular mechanisms of breast cancer metastases to bone

scientific article

Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells

scientific article published on 13 November 2017

New insights into the role of T cells in the vicious cycle of bone metastases

scientific article

Nf1 Haploinsufficiency Alters Myeloid Lineage Commitment and Function, Leading to Deranged Skeletal Homeostasis

scientific article

Optimizing and Profiling Prostaglandin E2 as a Medical Countermeasure for the Hematopoietic Acute Radiation Syndrome

scientific article published on 10 December 2020

Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment

scientific article published in June 2008

Osteolytic Breast Cancer Causes Skeletal Muscle Weakness in an Immunocompetent Syngeneic Mouse Model

scientific article published on 19 December 2017

Osteoporosis in men with prostate carcinoma receiving androgen-deprivation therapy: recommendations for diagnosis and therapies

scientific article published on March 2004

Overexpression of parathyroid hormone-related protein causes hypercalcemia but not bone metastases in a murine model of mammary tumorigenesis

scientific article published in July 2002

Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin

scientific article

Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone

scientific article

Preserving Well-being in Patients With Advanced and Late Prostate Cancer

scientific article published on 26 December 2020

Protein kinase Calpha regulates Ets1 transcriptional activity in invasive breast cancer cells.

scientific article published on April 2003

RANKL/RANK/MMP-1 molecular triad contributes to the metastatic phenotype of breast and prostate cancer cells in vitro

scientific article

Radium-223 mechanism of action: implications for use in treatment combinations

scientific article published on 11 November 2019

Regulation of postnatal trabecular bone formation by the osteoblast endothelin A receptor ⬇️

scientific article published on October 1, 2011

RhoGDI2 is an invasion and metastasis suppressor gene in human cancer

scientific article (publication date: 15 November 2002)

Role of TGF-β in breast cancer bone metastases.

scientific article published on October 2013

Role of bisphosphonates in prostate cancer bone metastases ⬇️

scientific article published on October 1, 2003

Role of endothelin-1 in osteoblastic bone metastases

scientific article

Single-Limb Irradiation Induces Local and Systemic Bone Loss in a Murine Model

scientific article published on 8 June 2015

Skeletal metastases: decreasing tumor burden by targeting the bone microenvironment

scientific article

Skeletal muscle Ca(2+) mishandling: Another effect of bone-to-muscle signaling

scientific article

Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases

scientific article

Systemic delivery of an oncolytic adenovirus expressing soluble transforming growth factor-β receptor II-Fc fusion protein can inhibit breast cancer bone metastasis in a mouse model

scientific article

Systemic delivery of oncolytic adenoviruses targeting transforming growth factor-β inhibits established bone metastasis in a prostate cancer mouse model

scientific article

TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone

scientific article published on 22 March 2019

TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases

scientific article

TGF-β in cancer and bone: implications for treatment of bone metastases

scientific article published on 10 August 2010

TGF-β in the Bone Microenvironment: Role in Breast Cancer Metastases ⬇️

scientific article published on July 12, 2011

TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis

scientific article

TGFβ-Mediated induction of SphK1 as a potential determinant in human MDA-MB-231 breast cancer cell bone metastasis

scientific article published on 8 July 2015

Tgf-Beta pathway as a therapeutic target in bone metastases

scientific article published in January 2010

The Biology of Bone Metastasis

scientific article

The Role of TGFβ in Bone-Muscle Crosstalk

scientific article published on 4 February 2017

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

scientific article

The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone

scientific article

The critical role of the bone microenvironment in cancer metastases

scientific article published on 16 July 2009

The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1

scientific article

The human Cyr61 gene is a transcriptional target of transforming growth factor beta in cancer cells

scientific article

The microenvironment matters: estrogen deficiency fuels cancer bone metastases

scientific article

The reaction of bone to tumor growth from human breast cancer cells in a rat spine single metastasis model

scientific article

The role of TGF-β in bone metastasis: novel therapeutic perspectives

scientific article published on 06 June 2012

The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm

scientific article

Therapeutic Strategies to Target TGF-β in the Treatment of Bone Metastases ⬇️

scientific article published on December 1, 2011

Transforming Growth Factor-Beta in Osteolytic Breast Cancer Bone Metastases ⬇️

scientific article published on October 1, 2003

Transforming growth factor-beta stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways

scientific article

Tumor-Bone Cell Interactions in Bone Metastases

Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-kappaB ligand pathway

scientific article published in December 2005

Tumor-expressed adrenomedullin accelerates breast cancer bone metastasis

scientific article

Tumor–bone interactions: there is no place like bone

Understanding and Optimizing Bone Health in Breast Cancer ⬇️

scientific article published on November 5, 2010

c-Fms Signaling Mediates Neurofibromatosis Type-1 Osteoclast Gain-In-Functions ⬇️

scientific article published on November 7, 2012

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