Search filters

List of works by Yongyuth Yuthavong

A genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates

scientific article

A simple dual selection for functionally active mutants of Plasmodium falciparum dihydrofolate reductase with improved solubility.

scientific article published on 24 August 2005

Alterations in membrane proteins of mouse erythrocytes infected with different species and strains of malaria parasites

scientific article published on January 1, 1979

An Examination of Complement Proteins on Membranes of Paroxysmal Nocturnal Haemoglobinuria (PNH) and PNH-like Red Cells ⬇️

scientific article published on March 1, 1979

An antimalarial peroxide from Amomum krervanh Pierre

An overview of chemotherapeutic targets for antimalarial drug discovery

scientific article

Anticancer properties of distinct antimalarial drug classes

scientific article (publication date: 2013)

Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase

scientific article

Antimalarial principles from Artemisia indica

scientific article published on 01 September 1998

Antimalarial sesquiterpenes from tubers of Cyperus rotundus: structure of 10,12-peroxycalamenene, a sesquiterpene endoperoxide

scientific article published on 01 September 1995

Application of loop-mediated isothermal amplification assay combined with lateral flow dipstick for detection of Plasmodium falciparum and Plasmodium vivax

scientific article published on 17 July 2014

Avian influenza A/H5N1 neuraminidase expressed in yeast with a functional head domain.

scientific article published on 11 December 2008

Basis for antifolate action and resistance in malaria.

scientific article published in February 2002

Binding of dihydroartemisinin to hemoglobin H: role in drug accumulation and host-induced antimalarial ineffectiveness of alpha-thalassemic erythrocytes

scientific article published on 01 March 1998

Binding of haemoglobin to spectrin of human erythrocytes

scientific article published on 01 January 1977

Biochemical and functional characterization of Plasmodium falciparum GTP cyclohydrolase I

scientific article (publication date: 19 April 2014)

C-16 artemisinin derivatives and their antimalarial and cytotoxic activities: syntheses of artemisinin monomers, dimers, trimers, and tetramers by nucleophilic additions to artemisitene.

scientific article

Characterization of Plasmodium falciparum serine hydroxymethyltransferase-A potential antimalarial target

scientific article (publication date: November 2009)

Characterization of Plasmodium knowlesi dihydrofolate reductase-thymidylate synthase and sensitivity to antifolates

scientific article published on 14 August 2018

Characterization of cobalamin-dependent methionine synthase purified from the human malarial parasite, Plasmodium falciparum

scientific article published on 01 January 1989

Characterization, crystallization and preliminary X-ray analysis of bifunctional dihydrofolate reductase-thymidylate synthase from Plasmodium falciparum

scientific article published on 23 March 2004

Cloning and heterologous expression of Plasmodium ovale dihydrofolate reductase-thymidylate synthase gene ⬇️

scientific article published on January 2, 2012

Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil

scientific article

Conflicting requirements of Plasmodium falciparum dihydrofolate reductase mutations conferring resistance to pyrimethamine-WR99210 combination.

scientific article

Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrin IX

scientific article published on 01 February 1997

Crystal structure of dihydrofolate reductase from Plasmodium vivax: pyrimethamine displacement linked with mutation-induced resistance

scientific article

Crystallization and preliminary crystallographic studies of dihydrofolate reductase-thymidylate synthase from Trypanosoma cruzi, the Chagas disease pathogen.

scientific article published on 30 October 2009

Decreased sensitivity of artesunate and chloroquine of Plasmodium falciparum infecting hemoglobin H and/or hemoglobin constant spring erythrocytes.

scientific article published on February 1989

Depression of Plasmodium falciparum dihydroorotate dehydrogenase activity in in vitro culture by tetracycline

scientific article published on 01 January 1988

Different states of sarcoplasmic reticulum membrane in the presence of acetyl phosphate and adenosine triphosphate ⬇️

scientific article published on September 1, 1977

Distinct biochemical properties of human serine hydroxymethyltransferase compared with the Plasmodium enzyme: implications for selective inhibition

scientific article

Effect of N-terminal truncation of Plasmodium falciparum dihydrofolate reductase on dihydrofolate reductase and thymidylate synthase activity.

scientific article

Effect of membrane modification on cell fusion of hen erythrocytes induced by dimethyl sulfoxide

scientific article published on 01 June 1978

Enhanced Ca2+ uptake by mouse erythrocytes in malarial (Plasmodium berghei) infection.

scientific article published in March 1983

Enhanced fusion capacity of malaria (Plasmodium berghei)-infected mouse red cells.

scientific article published in October 1980

Estimating mRNA lengths from Plasmodium falciparum genes by Virtual Northern RNA-seq analysis.

scientific article published on 5 November 2015

Evaluation of the activities of pyrimethamine analogs against Plasmodium vivax and Plasmodium falciparum dihydrofolate reductase-thymidylate synthase using in vitro enzyme inhibition and bacterial complementation assays.

scientific article

Flow cytometric enumeration of Plasmodium berghei-infected red blood cells stained with SYBR Green I.

scientific article published on 29 December 2011

Folate metabolism as a source of molecular targets for antimalarials.

scientific article published on June 2006

Heterogeneity in filterability of erythrocytes from malaria (Plasmodium berghei)-infected blood.

scientific article published in May 1982

High-performance liquid chromatographic assay for pteroylpolyglutamate hydrolase

scientific article published on 01 June 1987

High-performance liquid chromatographic assay for thymidylate synthase from the human malaria parasite, Plasmodium falciparum

scientific article published on 01 January 1989

High-performance liquid chromatographic determination of dihydroorotate dehydrogenase of Plasmodium falciparum and effects of antimalarials on enzyme activity

scientific article published on 01 November 1992

Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance

scientific article published on 07 November 2018

Immobilization of malarial (Plasmodium falciparum) dihydrofolate reductase for the selection of tight-binding inhibitors from combinatorial library.

scientific article

Inducible knockdown of Plasmodium gene expression using the glmS ribozyme

scientific article (publication date: 2013)

Inhibitors of multiple mutants of Plasmodium falciparum dihydrofolate reductase and their antimalarial activities.

scientific article published on January 2004

Insights into antifolate resistance from malarial DHFR-TS structures

scientific article (publication date: May 2003)

Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: structural basis of antifolate resistance

scientific article published on 01 May 2000

Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu).

scientific article published on May 1993

Key problems in science and technology in Thailand.

scientific article published in March 1985

Kinetic and molecular properties of dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium chabaudi

scientific article published on 01 March 1984

Kinetic mechanism and the rate-limiting step of Plasmodium vivax serine hydroxymethyltransferase

scientific article

Kinetic specificity in papain-catalysed hydrolyses ⬇️

scientific article published on August 1, 1971

Kinetics of the reaction of the masked sulphydryl groups of haemoglobins A, E and New York with p-chloromercuribenzoate.

scientific article published in March 1973

Mechanism-based development of new antimalarials: synthesis of derivatives of artemisinin attached to iron chelators

scientific article published on 01 June 1995

Molecular characterization of Plasmodium falciparum Bruno/CELF RNA binding proteins

scientific article (publication date: November 2014)

Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding.

scientific article published in May 2002

Particular interaction between pyrimethamine derivatives and quadruple mutant type dihydrofolate reductase of Plasmodium falciparum: CoMFA and quantum chemical calculations studies

scientific article published in April 2009

Phosphorylation of membrane proteins from Plasmodium berghei-infected red cells ⬇️

scientific article published on April 13, 1979

Plasmodium falciparum: asparagine mutant at residue 108 of dihydrofolate reductase is an optimal antifolate-resistant single mutant

scientific article published on 01 November 1997

Plasmodium serine hydroxymethyltransferase: indispensability and display of distinct localization

scientific article

Possible modes of action of the artemisinin-type compounds.

scientific article

Potentiating effect of pyrimethamine and sulfadoxine against dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium chabaudi

scientific article

Preclinical Evaluation of the Antifolate QN254, 5-Chloro- N'6'-(2,5-Dimethoxy-Benzyl)-Quinazoline-2,4,6-Triamine, as an Antimalarial Drug Candidate

scientific article

Protection against malaria by thalassaemia and haemoglobin variants.

scientific article published in July 1993

Rate constants of individual steps in papain-catalysed reactions ⬇️

scientific article published on March 14, 1978

Rational drug design approach for overcoming drug resistance: application to pyrimethamine resistance in malaria.

scientific article published in April 1998

Relation between Low Erythrocyte Acetylcholinesterase Activity and Membrane Lipids in Paroxysmal Noctural Haemoglobinuria ⬇️

scientific article published on March 1, 1979

Resistance to artemisinin of malaria parasites (Plasmodium falciparum) infecting alpha-thalassemic erythrocytes in vitro. Competition in drug accumulation with uninfected erythrocytes.

scientific article published on February 1994

Role of Plasmodium vivax Dihydropteroate Synthase Polymorphisms in Sulfa Drug Resistance.

scientific article published on 09 May 2016

Selection of drug resistant mutants from random library of Plasmodium falciparum dihydrofolate reductase in Plasmodium berghei model ⬇️

scientific article

Serine hydroxymethyltransferase from Plasmodium vivax is different in substrate specificity from its homologues.

scientific article published on 22 June 2009

Small-scale in vitro culture and purification of Plasmodium berghei for transfection experiment.

scientific article published in February 2011

Some chemical characteristics of dimethylsuberimidate and its effect on sarcoplasmic reticulum vesicles

scientific article published on 01 February 1975

Stimulation of Ca2+ uptake in the human liver fluke Opisthorchis viverrini by praziquantel

scientific article published on 01 May 1983

Stoichiometric selection of tight-binding inhibitors by wild-type and mutant forms of malarial (Plasmodium falciparum) dihydrofolate reductase.

scientific article published in March 2005

Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control.

scientific article

Subunit complementation of thymidylate synthase

scientific article published on October 27, 1992

Synthesis of solution-phase combinatorial library of 4,6-diamino-1,2-dihydro-1,3,5-triazine and identification of new leads against A16V+S108T mutant dihydrofolate reductase of Plasmodium falciparum.

scientific article

Target guided synthesis of 5-benzyl-2,4-diamonopyrimidines: their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from Plasmodium falciparum

scientific article (publication date: 15 January 2004)

The antimalarial action on Plasmodium falciparum of qinghaosu and artesunate in combination with agents which modulate oxidant stress

scientific article published on 01 January 1987

The relationship of phosphorylation of membrane proteins with the osmotic fragility and filterability of Plasmodium berghei-infected mouse erythrocytes.

scientific article published in July 1987

The role of tryptophan-48 in catalysis and binding of inhibitors of Plasmodium falciparum dihydrofolate reductase.

scientific article published on 14 January 2007

The structure of Plasmodium falciparum serine hydroxymethyltransferase reveals a novel redox switch that regulates its activities.

scientific article

Transgenic Plasmodium parasites stably expressing Plasmodium vivax dihydrofolate reductase-thymidylate synthase as in vitro and in vivo models for antifolate screening

scientific article

Trypanosomal Dihydrofolate Reductase Reveals Natural Antifolate Resistance ⬇️

scientific article published on June 16, 2011

Use of bacterial surrogates as a tool to explore antimalarial drug interaction: Synergism between inhibitors of malarial dihydrofolate reductase and dihydropteroate synthase.

scientific article published on 18 May 2015

pH-dependence and structure-activity relationships in the papain-catalysed hydrolysis of anilides.

scientific article published on August 1971

Paulina is supported by:

About Paulina

Help