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List of works by Theresa M. Reineke

A beta-cyclodextrin "click cluster" decorated with seven paramagnetic chelates containing two water exchange sites

scientific article

A polycation scaffold presenting tunable "click" sites: conjugation to carbohydrate ligands and examination of hepatocyte-targeted pDNA delivery

scientific article

Acrylic Triblock Copolymers Incorporating Isosorbide for Pressure Sensitive Adhesives

Advances in Polymer Design for Enhancing Oral Drug Solubility and Delivery.

scientific article published on 10 January 2018

Advancing polymeric delivery systems amidst a nucleic acid therapy renaissance

scientific article published on October 2013

Aggregated Solution Morphology of Poly(acrylic acid)-Poly(styrene) Block Copolymers Improves Drug Supersaturation Maintenance and Caco-2 Cell Membrane Permeation

scientific article published on 21 October 2019

Amide spacing influences pDNA binding of poly(amidoamine)s

scientific article

Architectural Control of Isosorbide-Based Polyethers via Ring-Opening Polymerization

scientific article published on 19 March 2019

Carbohydrate polymers for nonviral nucleic acid delivery

scientific article

Cationic glycopolymers for the delivery of pDNA to human dermal fibroblasts and rat mesenchymal stem cells ⬇️

scientific article published on December 3, 2011

Cell Penetrating Polymers Containing Guanidinium Trigger Apoptosis in Human Hepatocellular Carcinoma Cells unless Conjugated to a Targeting N-Acetyl-Galactosamine Block.

scientific article

Comparison of a tartaric acid derived polymeric MRI contrast agent to a small molecule model chelate

scientific article

Complexation between DNA and Hydrophilic-Cationic Diblock Copolymers.

scientific article

Complexation of Linear DNA and Poly(styrenesulfonate) with Cationic Copolymer Micelles: Effect of Polyanion Flexibility

scientific article

Computational Prediction and Experimental Verification of ε-Caprolactone Ring-Opening Polymerization Activity by an Aluminum Complex of an Indolide/Schiff-Base Ligand

scientific article published on 31 December 2018

Correlation of amine number and pDNA binding mechanism for trehalose-based polycations

scientific article

Crosslinker Chemistry Determines the Uptake Potential of Perfluorinated Alkyl Substances by β-Cyclodextrin Polymers

DNA delivery in vitro via surface release from multilayer assemblies with poly(glycoamidoamine)s

scientific article

Deciphering the role of hydrogen bonding in enhancing pDNA-polycation interactions

scientific article published on 18 August 2007

Degradable Thermosets from Sugar-Derived Dilactones

article by James J. Gallagher et al published 10 January 2014 in Macromolecules

Degradation of poly(glycoamidoamine) DNA delivery vehicles: polyamide hydrolysis at physiological conditions promotes DNA release

scientific article published in February 2010

Delivery of Proteins and Nucleic Acids: Achievements and Challenges

scientific article published on 01 February 2019

Design of Tunable Multicomponent Polymers as Modular Vehicles To Solubilize Highly Lipophilic Drugs

Diblock Terpolymers Are Tunable and pH Responsive Vehicles To Increase Hydrophobic Drug Solubility for Oral Administration

scientific article

Diblock glycopolymers promote colloidal stability of polyplexes and effective pDNA and siRNA delivery under physiological salt and serum conditions.

scientific article published on 15 July 2011

Diffusion of Drug Delivery Nanoparticles into Biogels Using Time-Resolved MicroMRI.

scientific article

Direct Observation of Nanostructures during Aqueous Dissolution of Polymer/Drug Particles

article published in 2017

Dissolution and Solubility Enhancement of the Highly Lipophilic Drug Phenytoin via Interaction with Poly(N-isopropylacrylamide-co-vinylpyrrolidone) Excipients

Effects of Hydrophobic Tail Length Variation on Surfactant-Mediated Protein Stabilization

scientific article published on 15 October 2020

Effects of Trehalose Polycation End-Group Functionalization on Plasmid DNA Uptake and Transfection ⬇️

scientific article published on July 18, 2012

Effects of trehalose click polymer length on pDNA complex stability and delivery efficacy

scientific article published on 07 February 2007

Efficient Polymer-Mediated Delivery of Gene-Editing Ribonucleoprotein Payloads through Combinatorial Design, Parallelized Experimentation, and Machine Learning

scientific article published on 23 November 2020

Equilibration of Micelle-Polyelectrolyte Complexes: Mechanistic Differences between Static and Annealed Charge Distributions.

scientific article

Exploring the mechanism of plasmid DNA nuclear internalization with polymer-based vehicles ⬇️

scientific article published on July 9, 2012

Facially amphiphilic polyionene biocidal polymers derived from lithocholic acid.

scientific article published on 23 February 2018

Fast, Efficient, and Gentle Transfection of Human Adherent Cells in Suspension

scientific article published in April 2016

From Condensed Lanthanide Coordination Solids to Microporous Frameworks Having Accessible Metal Sites

scientific article published in 1999

From Order to Disorder: Computational Design of Triblock Amphiphiles with 1 nm Domains

scientific article published on 11 May 2020

General structure-activity relationship for poly(glycoamidoamine)s: the effect of amine density on cytotoxicity and DNA delivery efficiency

scientific article

Glucose-Functionalized, Serum-Stable Polymeric Micelles from the Combination of Anionic and RAFT Polymerizations

Glucose-containing diblock polycations exhibit molecular weight, charge, and cell-type dependence for pDNA delivery.

scientific article

Glycopolycation-DNA Polyplex Formulation N/P Ratio Affects Stability, Hemocompatibility, and in Vivo Biodistribution

scientific article published on 28 March 2019

Heparin Enhances Transfection in Concert with a Trehalose-Based Polycation with Challenging Cell Types.

scientific article published on 19 December 2016

High-Throughput Excipient Discovery Enables Oral Delivery of Poorly Soluble Pharmaceuticals

scientific article (publication date: 26 October 2016)

Highlighting the role of polymer length, carbohydrate size, and nucleic acid type in potency of glycopolycation agents for pDNA and siRNA delivery

scientific article published on 16 October 2013

Hydroxyl stereochemistry and amine number within poly(glycoamidoamine)s affect intracellular DNA delivery

scientific article

In Vivo Delivery of Nucleic Acids via Glycopolymer Vehicles Affords Therapeutic Infarct Size Reduction In Vivo ⬇️

scientific article published on December 20, 2011

Interaction of Poly(ethylenimine)–DNA Polyplexes with Mitochondria: Implications for a Mechanism of Cytotoxicity ⬇️

scientific article published on July 18, 2011

Interaction of poly(glycoamidoamine) DNA delivery vehicles with cell-surface glycosaminoglycans leads to polyplex internalization in a manner not solely dependent on charge

scientific article

Interpolyelectrolyte Complexes of Polycationic Micelles and Linear Polyanions: Structural Stability and Temporal Evolution

scientific article

Investigating the effects of block versus statistical glycopolycations containing primary and tertiary amines for plasmid DNA delivery

scientific article

Isosorbide-based Polymethacrylates

Isothermal Titration Calorimetry for the Screening of Aflatoxin B1 Surface-enhanced Raman Scattering Sensor Affinity Agents

article

Lanthanide-containing polycations for monitoring polyplex dynamics via lanthanide resonance energy transfer

scientific article

Large Free Volume in Maximally Interpenetrating Networks: The Role of Secondary Building Units Exemplified by Tb2(ADB)3[(CH3)2SO]4·16[(CH3)2SO]1

article by Theresa M. Reineke et al published May 2000 in Journal of the American Chemical Society

Lipophilic Polycation Vehicles Display High Plasmid DNA Delivery to Multiple Cell Types

scientific article

Macrocyclic Eu3+ chelates show selective luminescence responses to anions

scientific article published on 8 February 2008

Macromolecular Imaging Agents Containing Lanthanides: Can Conceptual Promise Lead to Clinical Potential?

scientific article

Membrane and nuclear permeabilization by polymeric pDNA vehicles: efficient method for gene delivery or mechanism of cytotoxicity?

scientific article

Molecular Additives Significantly Enhance Glycopolymer-Mediated Transfection of Large Plasmids and Functional CRISPR-Cas9 Transcription Activation Ex Vivo in Primary Human Fibroblasts and Induced Pluripotent Stem Cells

scientific article published on 10 December 2018

Molecular Affinity Agents for Intrinsic Surface-Enhanced Raman Scattering (SERS) Sensors

Multiplex surface-enhanced Raman scattering detection of deoxynivalenol and ochratoxin A with a linear polymer affinity agent

scientific article published in 2020

N-Acetylgalactosamine Block-co-Polycations Form Stable Polyplexes with Plasmids and Promote Liver-Targeted Delivery

scientific article

New Insights into Quinine-DNA Binding Using Raman Spectroscopy and Molecular Dynamics Simulations

article

New poly(d-glucaramidoamine)s induce DNA nanoparticle formation and efficient gene delivery into mammalian cells

scientific article

Nonviral Gene Delivery with Cationic Glycopolymers

scientific article published on 17 April 2019

Optimization of film over nanosphere substrate fabrication for SERS sensing of the allergen soybean agglutinin

scientific article published on 4 November 2020

Optimizing linear polymer affinity agent properties for surface-enhanced Raman scattering detection of aflatoxin B1

scientific article published in 2019

Packaging pDNA by Polymeric ABC Micelles Simultaneously Achieves Colloidal Stability and Structural Control

scientific article published on 23 August 2018

Peptide-functionalized poly(ethylene glycol) star polymers: DNA delivery vehicles with multivalent molecular architecture

scientific article published on 04 October 2007

Poly(2 deoxy 2 methacrylamido glucopyranose) b Poly(methacrylate amine)s: Optimization of Diblock Glycopol ycations for Nucleic Acid Delivery

scientific article published on March 2013

Poly(glycoamidoamine) vehicles promote pDNA uptake through multiple routes and efficient gene expression via caveolae-mediated endocytosis

scientific article published in June 2010

Poly(glycoamidoamine)s for gene delivery. structural effects on cellular internalization, buffering capacity, and gene expression

scientific article published on January 2007

Poly(glycoamidoamine)s for gene delivery: stability of polyplexes and efficacy with cardiomyoblast cells

scientific article

Poly(glycoamidoamine)s: a broad class of carbohydrate-containing polycations for nucleic acid delivery ⬇️

scientific article published on June 24, 2011

Poly(trehalose): sugar-coated nanocomplexes promote stabilization and effective polyplex-mediated siRNA delivery.

scientific article published on October 2013

Polycation Architecture and Assembly Direct Successful Gene Delivery: Micelleplexes Outperform Polyplexes via Optimal DNA Packaging

scientific article published on 25 September 2019

Polycationic beta-cyclodextrin "click clusters": monodisperse and versatile scaffolds for nucleic acid delivery

scientific article

Polymer Day: Outreach Experiments for High School Students

Polymer beacons for luminescence and magnetic resonance imaging of DNA delivery

scientific article

Polymeric nanocylinders by combining block copolymer self-assembly and nanoskiving

scientific article

Polymeric nucleic acid vehicles exploit active interorganelle trafficking mechanisms

scientific article

Polyplexes Are Endocytosed by and Trafficked within Filopodia

scientific article published on 02 March 2020

Precise Compositional Control and Systematic Preparation of Multimonomeric Statistical Copolymers

article

Predictable Heating and Positive MRI Contrast from a Mesoporous Silica-Coated Iron Oxide Nanoparticle

scientific article published on 18 March 2016

SERS Detection of Ricin B-Chain via N-Acetyl-Galactosamine Glycopolymers

Solution-state polymer assemblies influence BCS class II drug dissolution and supersaturation maintenance

scientific article published on 03 January 2014

Spatiotemporal cellular imaging of polymer-pDNA nanocomplexes affords in situ morphology and trafficking trends

scientific article published on 30 September 2013

Stimuli-Responsive Polymers for Biological Detection and Delivery

article published in 2015

Structural effects of carbohydrate-containing polycations on gene delivery. 1. Carbohydrate size and its distance from charge centers

scientific article published on January 2003

Structural effects of carbohydrate-containing polycations on gene delivery. 2. Charge center type

scientific article published on January 2003

Structures and Protonation States of Hydrophilic-Cationic Diblock Copolymers and Their Binding with Plasmid DNA.

scientific article published on 23 February 2018

Structure–Activity Examination of Poly(glycoamidoguanidine)s: Glycopolycations Containing Guanidine Units for Nucleic Acid Delivery ⬇️

scientific article published on May 12, 2011

Synthesis, characterization, and luminescence properties of a new series of Eu3+-containing macrocycles

scientific article published in December 2005

Theranostics: Combining Imaging and Therapy ⬇️

scientific article published on August 29, 2011

Toward targeting RNA structure: branched peptides as cell-permeable ligands to TAR RNA.

scientific article published on 28 October 2011

Trehalose click polymers inhibit nanoparticle aggregation and promote pDNA delivery in serum

scientific article published on June 2006

Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery

scientific article

Tuning Cationic Block Copolymer Micelle Size by pH and Ionic Strength

scientific article published on 3 August 2016

Versatile supramolecular pDNA vehicles via "click polymerization" of beta-cyclodextrin with oligoethyleneamines

article published in 2009

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