List of works - Sabina Halappanavar

21st Century Tools for Nanotoxicology: Transcriptomic Biomarker Panel and Precision-Cut Lung Slice Organ Mimic System for the Assessment of Nanomaterial-Induced Lung Fibrosis

scientific article published on 29 April 2020

A framework for the use of single-chemical transcriptomics data in predicting the hazards associated with complex mixtures of polycyclic aromatic hydrocarbons

scientific article

Advances in gene delivery systems

scientific article published on 30 March 2015

Application of bi-clustering of gene expression data and gene set enrichment analysis methods to identify potentially disease causing nanomaterials

scientific article

Application of biclustering of gene expression data and gene set enrichment analysis methods to identify potentially disease causing nanomaterials

scientific article

Carbon black nanoparticle intratracheal instillation does not alter cardiac gene expression

scientific article published in December 2013

Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation

scientific article published on 6 November 2015

Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease

scientific article published on 22 January 2015

Characterization of in vitro genotoxic, cytotoxic and transcriptomic responses following exposures to amorphous silica of different sizes

scientific article

Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water

scientific article

Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials

scientific article

Exposure of pregnant mice to carbon black by intratracheal instillation: toxicogenomic effects in dams and offspring

scientific article published on 6 October 2011

Gender differences in murine pulmonary responses elicited by cellulose nanocrystals

journal article published in 2016

Genetic toxicology and toxicogenomic analysis of three cigarette smoke condensates in vitro reveals few differences among full‐flavor, blonde, and light products ⬇️

scientific article published on March 19, 2012

Hepatic and pulmonary toxicogenomic profiles in mice intratracheally instilled with carbon black nanoparticles reveal pulmonary inflammation, acute phase response, and alterations in lipid homeostasis

scientific article

IL-1 receptor regulates microRNA-135b expression in a negative feedback mechanism during cigarette smoke-induced inflammation

scientific article published on 25 February 2013

Identification of Gene Transcription Start Sites and Enhancers Responding to Pulmonary Carbon Nanotube Exposure in Vivo

scientific article published on 27 March 2017

Immunomodulation by gastrointestinal carbon black nanoparticle exposure in ovalbumin T cell receptor transgenic mice

scientific article published on 18 August 2016

Impact of cigarette smoke on the human and mouse lungs: a gene-expression comparison study

scientific article

Induction of the interleukin 6/ signal transducer and activator of transcription pathway in the lungs of mice sub-chronically exposed to mainstream tobacco smoke

scientific article published on 21 August 2009

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

scientific article published on 29 December 2014

Mapping Indicators of Toxicity for Polycyclic Aromatic Compounds in the Atmosphere of the Athabasca Oil Sands Region

scientific article

Maternal inhalation of surface-coated nanosized titanium dioxide (UV-Titan) in C57BL/6 mice: effects in prenatally exposed offspring on hepatic DNA damage and gene expression

scientific article published on 28 November 2011

Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials

scientific article

Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis

scientific article

Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes

scientific article

Predicting pulmonary fibrosis in humans after exposure to multi-walled carbon nanotubes (MWCNTs).

scientific article published on 23 May 2016

Promise and peril in nanomedicine: the challenges and needs for integrated systems biology approaches to define health risk

scientific article published on 15 March 2017

Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage ⬇️

scientific article published on April 30, 2011

Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation

scientific article published on April 2013

Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework

scientific article published on 13 September 2017

Subchronic oral exposure to benzo(a)pyrene leads to distinct transcriptomic changes in the lungs that are related to carcinogenesis

scientific article published on 18 May 2012

Time-dependent subcellular distribution and effects of carbon nanotubes in lungs of mice

scientific article

Toxicogenomic outcomes predictive of forestomach carcinogenesis following exposure to benzo(a)pyrene: relevance to human cancer risk

scientific article published on 02 June 2013

Toxicogenomics analysis of mouse lung responses following exposure to titanium dioxide nanomaterials reveal their disease potential at high doses

scientific article

Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response

scientific article published on 11 December 2014

Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles

scientific article published on 2 November 2017

Ubiquitin-dependent distribution of the transcriptional coactivator p300 in cytoplasmic inclusion bodies

scientific article published on 23 April 2007

List of works by Sabina Halappanavar

21st Century Tools for Nanotoxicology: Transcriptomic Biomarker Panel and Precision-Cut Lung Slice Organ Mimic System for the Assessment of Nanomaterial-Induced Lung Fibrosis

A framework for the use of single-chemical transcriptomics data in predicting the hazards associated with complex mixtures of polycyclic aromatic hydrocarbons

Advances in gene delivery systems

Application of bi-clustering of gene expression data and gene set enrichment analysis methods to identify potentially disease causing nanomaterials

Application of biclustering of gene expression data and gene set enrichment analysis methods to identify potentially disease causing nanomaterials

Carbon black nanoparticle intratracheal instillation does not alter cardiac gene expression

Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation

Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease

Characterization of in vitro genotoxic, cytotoxic and transcriptomic responses following exposures to amorphous silica of different sizes

Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water

Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials

Exposure of pregnant mice to carbon black by intratracheal instillation: toxicogenomic effects in dams and offspring

Gender differences in murine pulmonary responses elicited by cellulose nanocrystals

Genetic toxicology and toxicogenomic analysis of three cigarette smoke condensates in vitro reveals few differences among full‐flavor, blonde, and light products ⬇️

Hepatic and pulmonary toxicogenomic profiles in mice intratracheally instilled with carbon black nanoparticles reveal pulmonary inflammation, acute phase response, and alterations in lipid homeostasis

IL-1 receptor regulates microRNA-135b expression in a negative feedback mechanism during cigarette smoke-induced inflammation

Identification of Gene Transcription Start Sites and Enhancers Responding to Pulmonary Carbon Nanotube Exposure in Vivo

Immunomodulation by gastrointestinal carbon black nanoparticle exposure in ovalbumin T cell receptor transgenic mice

Impact of cigarette smoke on the human and mouse lungs: a gene-expression comparison study

Induction of the interleukin 6/ signal transducer and activator of transcription pathway in the lungs of mice sub-chronically exposed to mainstream tobacco smoke

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

Mapping Indicators of Toxicity for Polycyclic Aromatic Compounds in the Atmosphere of the Athabasca Oil Sands Region

Maternal inhalation of surface-coated nanosized titanium dioxide (UV-Titan) in C57BL/6 mice: effects in prenatally exposed offspring on hepatic DNA damage and gene expression

Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials

Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis

Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes

Predicting pulmonary fibrosis in humans after exposure to multi-walled carbon nanotubes (MWCNTs).

Promise and peril in nanomedicine: the challenges and needs for integrated systems biology approaches to define health risk

Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage ⬇️

Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation

Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework

Subchronic oral exposure to benzo(a)pyrene leads to distinct transcriptomic changes in the lungs that are related to carcinogenesis

Time-dependent subcellular distribution and effects of carbon nanotubes in lungs of mice

Toxicogenomic outcomes predictive of forestomach carcinogenesis following exposure to benzo(a)pyrene: relevance to human cancer risk

Toxicogenomics analysis of mouse lung responses following exposure to titanium dioxide nanomaterials reveal their disease potential at high doses

Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response

Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles

Ubiquitin-dependent distribution of the transcriptional coactivator p300 in cytoplasmic inclusion bodies