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List of works by Suzanne Lesage

A Novel Nonsense Mutation in DNAJC6 Expands the Phenotype of Autosomal-Recessive Juvenile-Onset Parkinson's Disease

scientific article

A clinical, neuropsychological and olfactory evaluation of a large family with LRRK2 mutations

scientific article

A comprehensive screening of copy number variability in dementia with Lewy bodies

scientific article published on 24 October 2018

A deleterious mutation in DNAJC6 encoding the neuronal-specific clathrin-uncoating co-chaperone auxilin, is associated with juvenile parkinsonism

scientific article

A genetic cluster of early onset Parkinson's disease in a Colombian population

scientific article published on December 2006

A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease

scientific article

A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants

scientific article

A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies

scientific article published on June 2013

A multitracer dopaminergic PET study of young-onset parkinsonian patients with and without parkin gene mutations.

scientific article published on 17 July 2009

A new F-box protein 7 gene mutation causing typical Parkinson's disease

scientific article published on 23 May 2015

A systematic screening to identify de novo mutations causing sporadic early-onset Parkinson's disease

scientific article

Additional rare variant analysis in Parkinson's disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance

scientific article

Alpha-synuclein gene rearrangements in dominantly inherited parkinsonism: frequency, phenotype, and mechanisms

scientific article published in January 2009

Alpha-synuclein repeat variants and survival in Parkinson's disease

scientific article

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

scientific article

Analysis of blood-based gene expression in idiopathic Parkinson disease

scientific article published on 15 September 2017

Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies

scientific article published on 29 January 2020

Assessing the prevalence of PINK1 genetic variants in South African patients diagnosed with early- and late-onset Parkinson's disease

scientific article published on 15 June 2010

Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study ⬇️

scientific article published on 30 August 2011

Autosomal recessive cortical myoclonic tremor and epilepsy: association with a mutation in the potassium channel associated gene CNTN2

scientific article

Biological effects of the PINK1 c.1366C>T mutation: implications in Parkinson disease pathogenesis.

scientific article published on 12 January 2007

C9orf72 repeat expansions are a rare genetic cause of parkinsonism

scientific article

CHCHD2 and Parkinson's disease.

scientific article published in July 2015

Characterization of recessive Parkinson's disease in a large multicenter study

scientific article published on 30 May 2020

Clinical features of Parkinson disease patients with homozygous leucine-rich repeat kinase 2 G2019S mutations

scientific article published in September 2006

Construction and validation of a Parkinson's disease mutation genotyping array for the Parkin gene

scientific article published in May 2007

DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study

scientific article

De novo mutations in HCN1 cause early infantile epileptic encephalopathy

scientific article

Deletion of the parkin and PACRG gene promoter in early-onset parkinsonism

scientific article

Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data

scientific article

Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study

scientific article

Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing

scientific article published on 30 January 2017

EIF4G1 in familial Parkinson's disease: pathogenic mutations or rare benign variants? ⬇️

scientific article published on June 1, 2012

EIF4G1 mutations do not cause Parkinson's disease

scientific article published on 9 May 2015

Editorial: Celebrating the Diversity of Genetic Research to Dissect the Pathogenesis of Parkinson's Disease

scientific article

Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study

scientific article

Familial Parkinson's disease/parkinsonism

scientific article published on 19 April 2015

Fine-mapping, gene expression and splicing analysis of the disease associated LRRK2 locus

scientific article

Frequency of the LRRK2 G2019S mutation in siblings with Parkinson's disease

scientific article

From genes to proteins in mendelian Parkinson's disease: an overview

scientific article published on December 2009

G2019S LRRK2 mutation in French and North African families with Parkinson's disease

scientific article published on November 2005

G51D α‐synuclein mutation causes a novel Parkinsonian–pyramidal syndrome ⬇️

scientific article published on April 1, 2013

Genetic characteristics of leucine-rich repeat kinase 2 (LRRK2) associated Parkinson's disease

scientific article published on August 2011

Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases

scientific article published on 05 June 2017

Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population

scientific article published on 17 November 2010

Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease

scientific article

Greater improvement in LRRK2 G2019S patients undergoing Subthalamic Nucleus Deep Brain Stimulation compared to non-mutation carriers

scientific article published in February 2016

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

scientific article

Insufficient evidence for pathogenicity of SNCA His50Gln (H50Q) in Parkinson's disease

scientific article published on 20 December 2017

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

scientific article published on 16 December 2017

LRRK2 G2019S mutation in Parkinson's disease: a neuropsychological and neuropsychiatric study in a large Algerian cohort

scientific article

LRRK2 G2019S mutation: frequency and haplotype data in South African Parkinson's disease patients

scientific article

LRRK2 exon 41 mutations in sporadic Parkinson disease in Europeans

scientific article published on March 2007

LRRK2 haplotype analyses in European and North African families with Parkinson disease: a common founder for the G2019S mutation dating from the 13th century

scientific article published in August 2005

LRRK2 is a major gene in North African parkinsonism

scientific article published in May 2006

Lack of evidence for a role of genetic variation in TMEM230 in the risk for Parkinson's disease in the Caucasian population

scientific article published on 11 October 2016

Large-scale assessment of polyglutamine repeat expansions in Parkinson disease

scientific article

Large-scale replication and heterogeneity in Parkinson disease genetic loci

scientific article

Large-scale screening of the Gaucher's disease-related glucocerebrosidase gene in Europeans with Parkinson's disease

scientific article published on 14 October 2010

Leucine-rich repeat kinase 2 is associated with the endoplasmic reticulum in dopaminergic neurons and accumulates in the core of Lewy bodies in Parkinson disease

scientific article published on September 2010

Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

scientific journal article

Loss-of-function mutations in RAB39B are associated with typical early-onset Parkinson disease

scientific article

Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines

scientific article

Mutation Analysis of Consanguineous Moroccan Patients with Parkinson's Disease Combining Microarray and Gene Panel

scientific article published on 31 October 2017

Mutation analysis of Parkinson's disease genes in a Russian data set

scientific article published on 09 July 2018

NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases

scientific article published on 17 May 2017

Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study

scientific article

PARKIN Inactivation Links Parkinson's Disease to Melanoma

scientific article published on 17 December 2015

PINK1 and FLNA mutations association: A role for atypical parkinsonism?

scientific article

Parkinson's disease in GTP cyclohydrolase 1 mutation carriers

scientific article

Parkinson's disease-related LRRK2 G2019S mutation results from independent mutational events in humans

scientific article

Penetrance estimate of LRRK2 p.G2019S mutation in individuals of non-Ashkenazi Jewish ancestry.

scientific article

Population-specific frequencies for LRRK2 susceptibility variants in the Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium

scientific article

Role of mendelian genes in "sporadic" Parkinson's disease

scientific article

Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease

scientific article published on 22 July 2011

Subthalamic nucleus stimulation is efficacious in patients with Parkinsonism and LRRK2 mutations

scientific article published in January 2007

Suggestive association between OPRM1 and impulse control disorders in Parkinson's disease.

scientific article published on 16 November 2018

The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism

scientific article published on 13 February 2013

The normal parkin sequence ⬇️

scientific article published on November 16, 2011

Use of support vector machines for disease risk prediction in genome-wide association studies: concerns and opportunities

scientific article published on 3 August 2012

What genetics tells us about the causes and mechanisms of Parkinson's disease

scientific article published on October 2011

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