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List of works by Fabrizio d'Adda di Fagagna

A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks

scientific article

A direct role for small non-coding RNAs in DNA damage response

scientific article published on 21 October 2013

A novel single-cell method provides direct evidence of persistent DNA damage in senescent cells and aged mammalian tissues

scientific article

BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment

scientific article published in Nature Communications

Cellular senescence: hot or what?

scientific article published on 30 January 2009

Corrigendum: DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs

scientific article published on 13 April 2017

DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors

scientific article published on 16 February 2016

DNA damage in mammalian neural stem cells leads to astrocytic differentiation mediated by BMP2 signaling through JAK-STAT

scientific article published on 25 July 2013

DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs

scientific article published on 27 February 2017

Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks

scientific article published on 27 November 2017

Detection of Telomeric DNA:RNA Hybrids Using TeloDRIP-qPCR

scientific article published on 21 December 2020

Epigenetic alterations associated with cellular senescence: a barrier against tumorigenesis or a red carpet for cancer?

scientific article published on 16 September 2011

Erratum: Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

article

Express or repress? The transcriptional dilemma of damaged chromatin

scientific article published on 23 February 2017

Faculty of 1000 evaluation for A complex secretory program orchestrated by the inflammasome controls paracrine senescence

From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond

scientific article published on 30 March 2018

Functional links between telomeres and proteins of the DNA-damage response

scientific article published in August 2004

Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors

scientific article published on 30 September 2019

Human nuclear ARGONAUTE 2 interacts in vivo only with small RNAs and not with DNA.

scientific article published on 13 May 2015

Human replication protein Cdc6 is selectively cleaved by caspase 3 during apoptosis

scientific article published on 15 July 2002

Identification of a DNA nonhomologous end-joining complex in bacteria

scientific journal article

Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome

scientific article published on 18 November 2019

Is cellular senescence an example of antagonistic pleiotropy?

scientific article published on 15 March 2012

Living on a break: cellular senescence as a DNA-damage response

scientific article published on July 2008

NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex

scientific article published on 10 August 2016

NOTCH1 modulates activity of DNA-PKcs.

scientific article

Need telomere maintenance? Call 911

scientific article published on 17 January 2007

Neural stem cells exposed to BrdU lose their global DNA methylation and undergo astrocytic differentiation

scientific article published on February 29, 2012

Never-ageing cellular senescence

scientific article published on 09 May 2011

Notch is a direct negative regulator of the DNA-damage response

scientific article

Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

scientific article

PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry

scientific article published on 16 February 2018

Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication

scientific article published on 14 April 2014

RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA

scientific article published on 19 December 2014

RNase A treatment and reconstitution with DNA damage response RNA in living cells as a tool to study the role of non-coding RNA in the formation of DNA damage response foci

scientific article published on 08 April 2019

Recent Advancements in DNA Damage-Transcription Crosstalk and High-Resolution Mapping of DNA Breaks

scientific article published on August 2017

Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae

scientific article published on 31 July 2015

SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence

scientific article published in 2023

SASPense and DDRama in cancer and ageing

scientific article

Site-specific DICER and DROSHA RNA products control the DNA-damage response

scientific article

Stable cellular senescence is associated with persistent DDR activation

scientific article

Target-enrichment sequencing for detailed characterization of small RNAs

scientific article published on 22 March 2018

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

scientific article published on 18 March 2012

The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku.

scientific article published on January 2003

Transcription and DNA Damage: Holding Hands or Crossing Swords?

scientific article published on 5 November 2016

Yeast Nhp6A/B and mammalian Hmgb1 facilitate the maintenance of genome stability

scientific article published in January 2005