List of works by Karin Scharffetter-Kochanek

A 9-centimorgan interval of chromosome 10 controls the T cell-dependent psoriasiform skin disease and arthritis in a murine psoriasis model.

scientific article

A Novel S100A8/A9 Induced Fingerprint of Mesenchymal Stem Cells associated with Enhanced Wound Healing.

scientific article published on 18 April 2018

A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.

scientific article

A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence

scientific article published on 4 December 2017

A neurofibroma-like tumor in a giant congenital nevus

scientific article published on 01 October 2018

A novel activity enhances promoter escape of RNA polymerase I.

scientific article

ABCB5 Identifies Immunoregulatory Dermal Cells

scientific article

ATM is required for SOD2 expression and homeostasis within the mammary gland.

scientific article

Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue

Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue

Acral erythrodysesthesia syndrome caused by intravenous infusion of docetaxel in breast cancer

scientific article published in December 2002

Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation

scientific article published on August 2006

Activation of protein kinase CK2 is an early step in the ultraviolet B-mediated increase in interstitial collagenase (matrix metalloproteinase-1; MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts

scientific article published on July 2002

Adaptive cellular protection against UVA-1-induced lipid peroxidation in human dermal fibroblasts shows donor-to-donor variability and is glutathione dependent

scientific article published on 18 November 2005

Adaptive immune response to model antigens is impaired in murine leukocyte-adhesion deficiency-1 revealing elevated activation thresholds in vivo

scientific article published on 4 March 2012

Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction

scientific article published on 11 April 2017

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

scientific article

Artefactual effects of oxygen on cell culture models of cellular senescence and stem cell biology

scientific article published on February 2011

Author Correction: A Novel S100A8/A9 Induced Fingerprint of Mesenchymal Stem Cells associated with Enhanced Wound Healing.

scientific article published on 2 July 2018

Beta(2) integrin deficiency yields unconventional double-negative T cells distinct from mature classical natural killer T cells in mice

scientific article published in October 2009

Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells

scientific article

Beta2 integrins separate graft-versus-host disease and graft-versus-leukemia effects

scientific article

Bexarotene monotherapy for patients with refractory Sézary syndrome.

scientific article published in January 2008

CD18 in monogenic and polygenic inflammatory processes of the skin

scientific article published on September 2006

CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks

scientific article

CD4+ T cell-associated pathophysiology critically depends on CD18 gene dose effects in a murine model of psoriasis

scientific article published in December 2003

CD5+ B cells from individuals with systemic lupus erythematosus express granzyme B.

scientific article published in July 2010

Calcinosis of the cutis and subcutis: an unusual nonimmunologic adverse reaction to subcutaneous injections of low-molecular-weight calcium-containing heparins

scientific article published in February 2004

Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation

scientific article

Cellular sensitivity to UV-irradiation is mediated by RNA polymerase I transcription

scientific article

Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to Aspergillus fumigatus hyphae

scientific article published on 21 January 2011

Cockayne syndrome protein A is a transcription factor of RNA polymerase I and stimulates ribosomal biogenesis and growth

scientific article

Corrigendum to “Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo” [Free Radic. Biol. Med. 38:1458–1470; 2005]

scholarly article published in Free Radical Biology and Medicine

Cutting edge: egress of newly generated plasma cells from peripheral lymph nodes depends on beta 2 integrin

scientific article published in June 2005

Dermatologic surgery in children: an update on indication, anesthesia, analgesia and potential perioperative complications

scientific article published on 12 February 2018

Direct comparison of [18F]FDG PET/CT with PET alone and with side-by-side PET and CT in patients with malignant melanoma.

scientific article published on 13 February 2007

Disclosure of the Culprits: Macrophages-Versatile Regulators of Wound Healing

scientific article published on September 2013

Effect of exercise on bone and articular cartilage in heterozygous manganese superoxide dismutase (SOD2) deficient mice

scientific article published on 4 February 2011

Empfehlung: Täglicher Lichtschutz in der Prävention chronischer UV-Schäden der Haut

Essential role of an activator protein-2 (AP-2)/specificity protein 1 (Sp1) cluster in the UVB-mediated induction of the human vascular endothelial growth factor in HaCaT keratinocytes

scientific article published on January 2003

Expression of stromal cell markers in distinct compartments of human skin cancers

scientific article published on February 2006

German guidelines for the diagnosis and therapy of localized scleroderma

scientific article published on February 2016

Giant cell arteritis with extensive scalp necrosis: A diagnostic and therapeutic challenge.

scientific article

Hematopoietic stem/progenitor cells directly contribute to arteriosclerotic progression via integrin β2

scientific article published on April 2015

Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation.

scientific article

Heterozygous deficiency of manganese superoxide dismutase in mice (Mn-SOD+/-): a novel approach to assess the role of oxidative stress for the development of nitrate tolerance

scientific article published on 2 June 2005

Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo

scientific article published in June 2005

Human dermal fibroblasts escape from the long-term phenocopy of senescence induced by psoralen photoactivation

scientific article published on April 2002

JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin

scientific article published in Nature Communications

Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein

scientific article

Key role of macrophages in the pathogenesis of CD18 hypomorphic murine model of psoriasis

scientific article published on 26 February 2009

Linking neuron and skin: matrix metalloproteinases in amyotrophic lateral sclerosis (ALS).

scientific article

Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome

MMP-2 and MMP-9 are elevated in spinal cord and skin in a mouse model of ALS.

scientific article published on 4 May 2010

MSCs rescue impaired wound healing in a murine LAD1 model by adaptive responses to low TGF-β1 levels

scientific article published on 21 February 2020

Management of refractory early-stage cutaneous T-cell lymphoma

scientific article

Management of refractory early-stage cutaneous T-cell lymphoma (mycosis fungoides) with a combination of oral bexarotene and psoralen plus ultraviolet bath therapy

scientific article published in March 2004

Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction

scientific article published on 02 July 2008

Mitochondrial oxidative stress and nitrate tolerance--comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SOD+/- mice

scientific article

Myiasis after study trip to French Guiana

scientific article

Neuronal redox imbalance results in altered energy homeostasis and early postnatal lethality

scientific article

Neutrophil primary granule proteins HBP and HNP1-3 boost bacterial phagocytosis by human and murine macrophages

scientific article

Osteopontin deficiency affects imiquimod-induced psoriasis-like murine skin inflammation and lymphocyte distribution in skin, draining lymph nodes and spleen.

scientific article

Overexpression of manganese superoxide dismutase in human dermal fibroblasts enhances the contraction of free floating collagen lattice: implications for ageing and hyperplastic scar formation

scientific article published on 22 March 2009

Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide-m

scientific article published on 10 August 2004

Oxidative stress in chronic venous leg ulcers

scientific article

Panniculitis induced by specific venom immunotherapy.

scientific article published in January 2004

Pathogenese von Wundheilungsstörungen bei älteren Patienten

scientific article published in March 2017

Pathogenesis of wound healing disorders in the elderly

scientific article published in March 2017

Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation

scientific article published on August 2006

Photoaging as a consequence of natural and therapeutic ultraviolet irradiation--studies on PUVA-induced senescence-like growth arrest of human dermal fibroblasts

scientific article published on November 2003

Photodamage and photoaging--prevention and treatment

scientific article published in September 2005

Pincer nail: aesthetic concept in surgery

scientific article

Psoralen plus UVA (PUVA) induced premature senescence as a model for stress-induced premature senescence

scientific article

Reactive oxygen intermediate-induced pathomechanisms contribute to immunosenescence, chronic inflammation and autoimmunity

scientific article published on 24 July 2009

Recommendation: daily sun protection in the prevention of chronic UV-induced skin damage

scientific article published in February 2007

Reduced CD18 levels drive regulatory T cell conversion into Th17 cells in the CD18hypo PL/J mouse model of psoriasis

scientific article

Reduction of CD18 promotes expansion of inflammatory γδ T cells collaborating with CD4+ T cells in chronic murine psoriasiform dermatitis

scientific article published on 4 November 2013

RhoH is important for positive thymocyte selection and T-cell receptor signaling

scientific journal article

Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington's disease

scientific article published on 17 August 2017

Role of beta2-integrins for homing and neovascularization capacity of endothelial progenitor cells

scientific article

S1-Guidelines on UV phototherapy and photochemotherapy

scientific article published in August 2016

Self-detection frequency and recognition patterns in medium to high-risk cutaneous melanoma patients

scientific article published on January 2017

Senescent BALB/c mice are able to develop resistance to Leishmania major infection

scientific article published on September 2004

Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration

scientific article published on 18 November 2016

Site of blood vessel damage and relevance of CD18 in a murine model of immune complex-mediated vasculitis.

scientific article published on 28 September 2006

Small molecular antioxidants effectively protect from PUVA-induced oxidative stress responses underlying fibroblast senescence and photoaging

scientific article published on 17 May 2008

Special section: Replication stress, a threat to the nuclear and mitochondrial genome

scientific article published on 5 January 2018

Spina Bifida

Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN.

scientific article

Suppression of Neutrophil-Mediated Tissue Damage-A Novel Skill of Mesenchymal Stem Cells

scientific article published on 14 June 2016

Syk-mediated translocation of PI3Kdelta to the leading edge controls lamellipodium formation and migration of leukocytes

scientific article (publication date: 2007)

T-cell plasticity in inflammatory skin diseases--the good, the bad, and the chameleons

scientific article published on 08 June 2015

TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis

scientific article

TLR4-dependent shaping of the wound site by MSCs accelerates wound healing

scientific article published on 12 March 2020

TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fibrosis in murine full-thickness skin wounds

scientific article

Telomerase stimulates ribosomal DNA transcription under hyperproliferative conditions

scientific article published on 13 August 2014

The cerebro-morphological fingerprint of a progeroid syndrome: white matter changes correlate with neurological symptoms in xeroderma pigmentosum

scientific article (publication date: 2012)

The effect of adipose tissue derived MSCs delivered by a chemically defined carrier on full-thickness cutaneous wound healing.

scientific article

The role of manganese superoxide dismutase in skin aging

scientific article published on July 2012

The role of vitamin C in pushing back the boundaries of skin aging: an ultrasonographic approach

scientific article

Therapierefraktäre Schwellung und Rötung der Bauchdecke.

scientific article

Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model

scientific article published on March 2013

Truncated Cockayne syndrome B protein represses elongation by RNA polymerase I.

scientific article

Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice

scientific article published on 5 April 2012

UVA-1 exposure in vivo leads to an IL-6 surge within the skin

scientific article published on 17 January 2017

Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events

scientific article

Uncoupling protein 2 protects mice from aging

scientific article published on 27 June 2016

Wound healing defect of Vav3-/- mice due to impaired {beta}2-integrin-dependent macrophage phagocytosis of apoptotic neutrophils.

scientific article published on 15 January 2009

Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiation

scientific article

[Early detection of skin cancer].

scientific article published in March 2014

p16INK4A is a robust in vivo biomarker of cellular aging in human skin.

scientific article

β2 integrin mediates hantavirus-induced release of neutrophil extracellular traps

scientific article

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